Stress is a response to external environmental conditions that encourages individuals to pursue changes in their lives. We examine the relationship between stress and federal and provincial political leaders’ approval ratings. We theorize that, as a strategy to cope with the pandemic stresses outside of their direct control, individuals will redirect their frustrations toward incumbents. We hypothesize that greater experiences with stress will negatively correlate with the approval of political incumbents even among members of incumbents’ political in-group. We analyze data from the COVID-19 Monitor survey, a multi-wave, cross-sectional survey of over 56,000 Canadians. On three out of four measures, we find that stress negatively impacted incumbent approval, and that these negative impacts occur among the incumbent’s supporters and non-supporters. On the fourth measure, we find the effect of stress on approval is moderated, positive or negative, by whether regional leaders took action to limit the spread of coronavirus disease 2019.

In 2024, the U.S. Government introduced, and then quickly rescinded, a new policy to oversee Dual Use Research of Concern (DURC) and Pathogens with Enhanced Pandemic Potential (PEPP). This research explores how biosafety practitioners interpreted and assessed the policy itself and discussed challenges to implementation. An inductive, grounded theory approach was used to identify key insights from qualitative data generated at a 2-day deliberative workshop with 45 biosafety officers, compliance professionals and researchers; analysis was supported using NVivo software. Participants described the policy’s ambiguous language, lack of actionable federal guidance, limited legal scope and unfunded administrative burdens as significant barriers to implementation. Although supportive of the policy’s goals, workshop participants stressed the need for more precise definitions, practical examples and practitioner-informed implementation strategies. The findings demonstrate that durable and effective biosafety and biosecurity oversight requires early, substantive engagement with those operationalizing policy.

A novel family of statistical distributions, called enriched truncated exponentiated generalized family, is theoretically developed to model heavy-tailed data. One of the three-parameter sub-models of this family derived from log-logistic distribution is comprehensively studied. The statistical properties are explored, including moments and Fisher information matrix. In addition, tail-heaviness is studied using the tail-index approach. The method of maximum likelihood is used for parameter estimation, and existence and uniqueness of these estimators are shown. The flexibility of the new family is further validated by applying to the Norwegian fire insurance claim dataset. The goodness-of-fit measures are used to illustrate the adequacy of the proposed family of distributions. Furthermore, a backtesting procedure is conducted for well-known risk measures to assess the accuracy of the right tail fit.

United Nations Declaration on the Rights of Indigenous Peoples — status in Canadian law — Indigenous children, youth, and families

The rise of digital money may bring about privately issued money that circulates across borders and coexists with public money. This paper uses an open-economy search model with multiple currencies to study the impact of such global money on monetary autonomy – the capacity of central banks to set a policy instrument. I show that the circulation of global money can entail a loss of monetary autonomy, but it can be preserved if government policy that limits the amount or use of global money for transactions is introduced or if the global currency is subject to the threat of counterfeiting. The result suggests that global digital money and monetary autonomy can be compatible.

This article addresses the questions of when mental health advance planning documents are created, the points when circumstances which they are intended to address arise and what consequences should flow when such a situation does arise. It addresses these points primarily from the perspective of what the law could/should be at a conceptual level. It looks at three stages: (a) creation of the document; (b) the period between the creation of the document and the point at which the intended circumstances arise; and (c) the point at which the intended circumstances arise. It does not purport to provide solutions at each stage, but rather to frame the dilemmas to aid discussion. In similar vein, it draws upon case studies from England & Wales, not to purport to dictate similarities of approach, but to flesh out dilemmas that have arisen to stimulate consideration.

The famous Sidorenko’s conjecture asserts that for every bipartite graph $H$, the number of homomorphisms from $H$ to a graph $G$ with given edge density is minimised when $G$ is pseudorandom. We prove that for any graph $H$, a graph obtained from replacing edges of $H$ by generalised theta graphs consisting of even paths satisfies Sidorenko’s conjecture, provided a certain divisibility condition on the number of paths. To achieve this, we prove unconditionally that bipartite graphs obtained from replacing each edge of a complete graph with a generalised theta graph satisfy Sidorenko’s conjecture, which extends a result of Conlon, Kim, Lee and Lee [J. Lond. Math. Soc., 2018].

The notions of “emergence” and “becoming” have become widely adopted in relational studies in archaeology, but their definition and application remain nebulous. We advocate a middle-range approach to the incorporation of these related concepts into the study of migration and pronounced cultural shifts. Our study relies on the Bayesian modeling of a significant corpus of radiocarbon dates from Mississippian sites in the Tombigbee Valley of southeastern North America. This investigation has identified the likelihood of two broad migration episodes that we hypothesize are related to cultural rephrasings of landscape and temporality.

While the effects of multidisciplinary weight loss (WL) on resting energy expenditure remain unclear in adolescents with obesity, the potential presence of adaptive thermogenesis (AT) has never been explored, which was the objective of the present work. Twenty-six adolescents (14·1 (sd 1·5) years) with severe obesity completed a 9-month inpatient multidisciplinary intervention followed by a 4-month follow-up. Anthropometric measurements, body composition (dual X-ray absorptiometry) and resting energy expenditure (REE, indirect calorimetry) were assessed before (T0) and after 9 months of WL intervention (T1) and after a 4-month follow-up (T2). AT, at the level of REE, was defined as a significantly lower measured v. predicted (using regression models with baseline data) REE. Two pre-cited REE equations were used, using both fat mass and fat-free mass (FFM) (predicted REE using equation 1) or FFM only (predicted REE using equation 2). Measured and predicted REE significantly decreased between T0 and T1 (P < 0·001) and remained lower at T2 compared with T0 (measured REE: P = 0·017; predicted REE: P < 0·001). Predicted REE using equation 2 was significantly higher than measured REE at T1 (P = 0·012), suggesting the presence of AT. FFM at T0 was negatively correlated with ATp1T1 (Rho = –0·428; P = 0·033) and ATp2T1 (Rho = –0·485; P = 0·014). The variation of FFM between T0 and T1 was negatively correlated with AT at T1 and T2. These preliminary results suggest the existence of AT in response to WL in adolescents with obesity, independently of the degree of WL. AT was associated with subsequent body weight and fat regain, suggesting AT may represent a damper to WL attempts while increasing the adolescents’ risks for subsequent weight and adiposity rebounds.

Salmonella enterica serovar Dublin is host-specific to cattle, causing severe symptoms and economically impacting milk herds. Despite an eradication programme in Denmark, levels of infection have not decreased and suspicion has fallen on the common starling Sturnus vulgaris as a potential vector between herds. The number of breeding starlings in Denmark declined by 60% between 1976 and 2015, a trend correlated with decreases in the number of cattle grazing outside. Ironically, more starlings are now coming into Danish cattle sheds to feed on maize silage outside the breeding season, so it is increasingly important to understand the role of starlings in dispersing Salmonella between cattle herds. We caught and tested 394 different starlings at seven separate dairy farms infected with Salmonella Dublin by swabbing breast feathers, legs, feet and undertail coverts as well as taking faecal samples at these and four other infected farms. We found no trace of the pathogen, indicating that starlings are highly unlikely to be significant in spreading Salmonella Dublin between Danish cattle herds. We recommend investigating alternative contacts that may occur between herds as the cause of disease spread.