Lamotrigine is beneficial in bipolar disorder and is often prescribed to patients during their period of reproductive potential. We summarise aspects of the pharmacology of lamotrigine, highlight its uses in psychiatric practice, drawing attention to recent findings relating to potential hazards arising from lamotrigine exposure in utero, and make some suggestions for clinical management.

Revolutionary exports are essential to studying China’s relations with Southeast Asia during the Cold War, particularly regarding communist parties in neighbouring countries that received substantial logistical support from China, enabling them to sustain armed struggles. However, previous research has been limited due to the topic’s sensitivity and the scarcity of Chinese-language sources. This article seeks to uncover the logistical system centred on Mengla, Yunnan, designed to support Southeast Asian communist parties, mainly in Laos. By examining the development of Chinese logistics units and the extensive clandestine aid networks (including road construction) that linked China with Laos, this article argues that China’s integrated civil-military logistics support was pivotal in sustaining armed resistance in Southeast Asia and countering the influence of the United States in the region. Additionally, the article examines the dimensions of the Cold War in Asia from the perspective of the ordinary individuals who were direct participants.

Reduced access to dementia healthcare services by elders from ethnic minority backgrounds is often a manifestation of underlying systemic disadvantages within dementia assessment and treatment services. In this narrative review of current literature on UK dementia healthcare services we identify risk factors contributing to the inequalities faced by people with dementia from ethnic minorities, point to major knowledge gaps in dementia diagnosis, management and long-term care for these groups and highlight clinical challenges arising in delivering services to them. We describe the inequity in diagnostic rates, their poorer treatment outcomes and the lack of culture-specific support for people from ethnic minority communities. We present proposals for South Asian and the Black ethnic minority groups by which local healthcare systems may minimise some of these disadvantages. This will enhance our understanding of the aetiology and management of long-term conditions such as dementia by improving access to and dialogue with ethnic minority communities and healthcare providers.

Threat sensitivity, an individual difference construct reflecting variation in responsiveness to threats of various types, predicts physiological reactivity to aversive stimuli and shares heritable variance with anxiety disorders in adults. However, no research has been conducted yet with youth to examine the heritability of threat sensitivity or evaluate the role of genetic versus environmental influences in its relations with mental health problems. The current study addressed this gap by evaluating the psychometric properties of a measure of this construct, the 20-item Trait Fear scale (TF-20), and examining its phenotypic and genotypic correlations with different forms of psychopathology in a sample of 346 twin pairs (121 monozygotic), aged 9–14 years. Analyses revealed high internal consistency and test-retest reliability for the TF-20. Evidence was also found for its convergent and discriminant validity in terms of phenotypic and genotypic correlations with measures of fear-related psychopathology. By contrast, the TF-20’s associations with depressive conditions were largely attributable to environmental influences. Extending prior work with adults, current study findings provide support for threat sensitivity as a genetically-influenced liability for phobic fear disorders in youth.

The 1920s to 1950s was a period of significant transformation and conflict in South and East Asia, marked by the forces of (anti-)imperialism, nationalism, and militarism, eventually escalating into the Second Sino-Japanese War and the Second World War. For a long time, internationalist initiatives hoped that de-escalation and peace could be achieved through diplomacy and exchange. Part of this approach included Asian Christians moving in the milieu of Protestant internationalism, a movement long dominated by American organizations and actors, which after the First World War saw a shift towards Asia—both in terms of representation from and interest in the region.

Between the 1920s and the 1950s, numerous international conferences, organized by missionary associations and organizations such as the World Student Christian Federation or the international Young Men’s Christian Association, debated the political future of Asia in a changing and increasingly belligerent world. The period also witnessed numerous exchanges of Christian delegations between individual countries. By analysing the interrelated histories of three Asian Protestant internationalists—T. Z. Koo of China, Kagawa Toyohiko of Japan, and Augustine Ralla Ram of India—the article offers an examination of the mechanics of Christian diplomacy before, during, and after war. It shows that Protestant internationalist diplomacy, fellowship, and solidarity were often overshadowed by national and political ideologies. However, the article further argues that, despite its shortcomings, which challenged transnational solidarity and fellowship, Christian diplomacy was characterized by a resilience and reach that allowed its Asian protagonists a remarkable international operating space by providing useful networks, opportunities, and resources.

Bullying among girls is often subtle and relational, which can go unnoticed by parents, teachers and healthcare professionals. This article explores how covert aggression – such as social exclusion, gossip and emotional manipulation – can cause profound psychological harm to targeted girls, many of whom may not even realise they are being bullied. Through an analysis of defining attributes of girl-to-girl bullying and general implications for mental health, this article aims to highlight the importance of early identification and treatment. The article also points out how social patterns of bullying found predominantly in girls’ social circles carry over well into adulthood, emerging in the work environment, social circles and cyberspace. Focused on practical application, this educational paper aims to enhance clinicians’, caregivers’ and teachers’ recognition of relational aggression, develop collaborative approaches to prevention and facilitate useful interventions for those affected. Ultimately, increased sensitivity to subtle bullying has the power to reduce subsequent harm and result in healthier social contexts.

Kwalitatieve interviews onder 100 verdachten in Nederlandse strafzaken bieden inzicht in de vraag of ervaren procedurele rechtvaardigheid ertoe doet voor verdachten en, zo ja, welke componenten van procedurele rechtvaardigheid voor hen van belang zijn. Het epistemologische vertrekpunt van dit onderzoek verschilt van de kwantitatieve studies die het onderzoeksveld domineren, doordat dit onderzoek nagaat welke componenten van procedurele rechtvaardigheid respondenten eventueel zelf ter sprake brengen in plaats van respondenten te vragen naar vooraf bepaalde componenten van procedurele rechtvaardigheid. De grote meerderheid van de respondenten bracht zelf kwesties ter sprake die met procedurele rechtvaardigheid te maken hebben. Zes componenten vormden de kern van hun rechtvaardigheidspercepties: (1) informatie waarop beslissingen zijn gebaseerd, (2) bejegening, (3) gepaste aandacht, (4) neutraliteit, (5) inspraak en (6) zorgvuldigheid. Hoewel deze componenten overeenkomen met de literatuur over procedurele rechtvaardigheid, noemden respondenten sommige componenten vaker – en andere juist minder vaak – dan men op basis van de literatuur zou verwachten. In het bijzonder speelt neutraliteit een belangrijke rol in de Nederlandse rechtbankcontext die hier werd onderzocht.

Appeals to “decolonize” now range widely, from decolonizing the university to decolonizing Russia. This article poses the question of what work the concept of decolonization can and cannot do. It underscores how much can be learned about how decolonization came about if one explores the different goals that activists sought in their time. It suggests that if instead of looking for a colonial “legacy,” we explore historical trajectories of colonization and decolonization, we can reveal how political, economic, and social structures in both ex-colonies and ex-metropoles were shaped and reshaped over time. Finally, it brings into conversation with the literature on the decolonization of the empires of Western European states more recent scholarship on Russia and the Soviet Union, pointing to different forms of imperial rule and imperial collapse and also to the possibility of “reimperialization,” of reconstituting empire in new contexts.

The development of externalizing behavior in young children is shaped by the complex interaction of temperament, neural mechanisms, and environmental factors. This study explored how child frontal alpha asymmetry (FAA) and child negative affect jointly moderate the relationship between mindful parenting and child externalizing behavior. The sample, drawn from families in the Netherlands, included reports from 128 mothers and 103 partners on mindful parenting, and on children’s negative affect and externalizing behavior. FAA was measured in 95 four-year-old children during an EEG session while they watched an animated video. Results indicated that children with high negative affect and greater left-sided FAA displayed the most externalizing behavior when maternal mindful parenting was low, but the least when mindful parenting was high. In contrast, no significant effects were found for children with lower negative affect or in partner-reported data. These findings suggest that children with both high negative affect and greater left-sided FAA are more sensitive to the quality of mindful parenting, particularly from mothers, aligning with the environmental sensitivity framework. Future research should replicate these findings, ideally in a larger sample, and further examine the long-term, cumulative impact of FAA and negative affect on the development of behavioral problems.