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Comorbidities, which are additional health conditions that occur alongside diabetes, can have a significant effect on blood sugar control. These conditions often complicate the management of diabetes and worsen overall health. Malnutrition, on the other hand, is a common concern for people with diabetes due to difficulties with food intake and metabolism. Proper nutrition is crucial for maintaining general health and effectively managing the disease. However, the extent of comorbidities and malnutrition within this group is not well understood in the study area. A cross-sectional study was conducted at Hawassa governmental hospitals between April and May 2023, involving 422 adult outpatients living with diabetes. The study aimed to evaluate their comorbidities, nutritional status, and associated factors. The required data were collected using structured and semi-structured questionnaires. Bivariate and multivariate logistic regression analyses were conducted using SPSS version 25.0. Undernutrition and concordant comorbidities were prevalent in the study population, occurring at rates of 15.2% and 57.8%, respectively. Additionally, 18.5% of participants were classified as overweight and obese with a BMI greater than 25 kg/m2. Three significant predictors of undernutrition among adult outpatients living with diabetes were identified: alcohol intake (P < 0.05), comorbidities (P < 0.01), and educational status (P < 0.05). Concordant comorbidity was notably common in these patients. It is recommended that the healthcare system consider comorbid conditions when managing diabetes. A longitudinal study is suggested to provide stronger evidence on these findings.
We aimed to validate in-body bioelectrical impedance analysis (BIA) measures with dual-energy X-ray absorptiometry (DXA) as reference and describe the body composition (BC) profiling of Tibetan adults.
Design:
This cross-sectional study included 855 participants (391 men and 464 women). Correlation and Bland–Altman analyses were performed for method agreement of in-body BIA and DXA. BC were described by obesity and metabolic status.
Setting:
In-body BIA and DXA have not been employed to characterise the BC of the Tibetan population living in the Qinghai–Tibet Plateau.
Participants:
A total of 855 Tibetan adults, including 391 men and 464 women, were enrolled in the study.
Results:
Concordance correlation coefficient for total fat mass (FM) and total lean mass (LM) between in-body BIA and DXA were 0·91 and 0·89. The bias of in-body BIA for percentages of total FM and total LM was 0·91 % (2·46 %) and –1·74 % (–2·80 %) compared with DXA, respectively. Absolute limits of agreement were wider for total FM in obese men and women and for total LM in overweight men than their counterparts. Gradience in the distribution of total and regional FM content was observed across different BMI categories and its combinations with waist circumference and metabolic status.
Conclusions:
In-body BIA and DXA provided overall good agreement at the group level in Tibetan adults, but the agreement was inferior in participants being overweight or obese.
The association between salt and salted food consumption and oral, pharyngeal, and oesophageal cancers remains inconclusive. To address this, we conducted a large-scale nationwide cohort study in Japan, a region globally recognised for its high-salt consumption. In a baseline survey conducted from 1988 to 1990, salt consumption was evaluated using a self-administered food frequency questionnaire in a sample of 42,535 participants aged 40–79 years. Over a median 14.4-year follow-up period, 145 incident cases of oral (n=43), pharyngeal (n=17), and oesophageal (n=85) cancers were observed. A Cox proportional hazards model was used to estimate the hazard ratio (HR) and 95% confidence interval (CI) after adjusting for age, sex, smoking status, alcohol consumption, and fruit and vegetable consumption. High-salt consumption was associated with a higher risk of oral, pharyngeal, and oesophageal cancers combined; the multivariable HR for the highest versus lowest tertiles of salt consumption was 1.67 (95% CI: 1.08–2.61, P-trend = 0.01). An excess risk was primarily observed for oral and oesophageal cancers. Among the salt sources, miso soup consumption was positively associated with the combined risk of oral, pharyngeal, and oesophageal cancers; however, the consumption of other high-salt foods was not. In conclusion, high-salt consumption was associated with a higher combined risk of oral, pharyngeal, and oesophageal cancers.
American diets are increasingly based on ultra-processed foods (UPF). Current research, particularly on socio-economic differentials, is lacking. This study aimed to provide an updated examination of US household purchases of UPF and how this differs by race–ethnicity, household income and household education.
Design:
The NielsenIQ Consumer Panel 2020 was utilised for analysis. Each food and beverage product purchased by US households was assigned a level of processing under the Nova level of processing classification system. The volume of UPF purchased overall and by food group was determined for each Nova processing group and examined by race–ethnicity, education and income. Results were stratified by race–ethnicity within each income group. A P value < 0·0001 was considered significant.
Setting:
This study analysed data from the Nielsen IQ Consumer Panel 2020 which recorded household food purchases in the USA.
Participants:
The Nielsen IQ Homescan Consumer Panel is a nationally representative longitudinal survey of around 35 000 and 60 000 US households.
Results:
Of 33 054 687 products purchased by 59 939 US households in 2020, 48 % of foods and 38 % of beverages were considered UPF. Categories with the highest proportion of purchases deriving from UPF included carbonated soft drinks (90 %), mixed dishes and soups (81 %) and sweets and snacks (71 %). Slightly higher but statistically significant proportions of UPF purchases occurred in the lowest income and education groups and among non-Hispanic whites.
Conclusions:
It is concerning that household purchases of UPF in the USA are high. Policies that reduce consumption of UPF may help reduce diet-related health inequalities.
The effect of dietary FODMAP (fermentable oligo-, di- and mono-saccharides and polyols) in healthy adults is poorly documented. This study compared the specific effects of low and moderate FODMAP intake (relative to typical intake) on the faecal microbiome, participant-reported outcomes and gastrointestinal physiology. In a single-blind cross-over study, twenty-five healthy participants were randomised to one of two provided diets, ‘low’ (LFD) <4 g/d or ‘moderate’ (MFD) 14–18 g/d, for 3 weeks each, with ≥ 2-week washout between. Endpoints were assessed in the last week of each diet. The faecal bacterial/archaeal and fungal communities were characterised by eighteen participants from whom high-quality DNA was extracted by 16S rRNA and internal transcribed spacer 2 (ITS2) profiling and metagenomic sequencing. There were no differences in gastrointestinal or behavioural symptoms (fatigue, depression, anxiety) or faecal characteristics and biochemistry (including SCFA). Mean colonic transit time (telemetry) was 23 (95 % CI: 15, 30) h with the MFD compared with 34 (24, 44) h with LFD (n 12; P = 0·009). Fungal diversity (richness) increased in response to MFD, but the bacterial richness was reduced, coincident with the expansion of the relative abundances of Bifidobacterium, Anaerostipes and Eubacterium. Metagenomic analysis showed expansion of polyol-utilising Bifidobacteria and Anaerostipes with MFD. In conclusion, short-term alterations of FODMAP intake are not associated with symptomatic, stool or behavioural manifestations in healthy adults, but remarkable shifts within the bacterial and mycobiome populations were observed. These findings emphasise the need to quantitatively assess all microbial domains and their interrelationships to improve understanding of the consequences of diet on gut function.
The Brazilian Worker’s Food Program (WFP) is a public policy initiative that focuses on nutritional assistance for low-income formal workers (less than five minimum wages). Currently, it serves more than 25 million formal workers (around 54%). This systematic review aimed to assess the nutritional quality of meals offered and/or consumed by beneficiaries of the WFP. Observational studies conducted with workers from companies registered in the programme were eligible, with no restrictions on the period of publication. The nutritional quality was assessed according to the guidelines of the programme (Normative Ordinance No. 66/2006). Twenty cross-sectional studies and one cohort study met the inclusion criteria. Most of the participants were male, from manufacturing industries, and their average age was 35.0 years. The results of the analysis showed that fibre, sodium, calories, and proteins were the nutrients that most exceeded the recommended amounts, whereas carbohydrate was the nutrient that had the least amount. The results showed that the nutritional quality of the food offered to or consumed by workers did not fully meet the required guidelines and, in some companies, did not promote an adequate and healthy diet. The WFP has great potential and needs to be reformulated to make it a programme that contributes to strengthening the realisation of the human right to adequate food.
Childhood obesity is increasing in many countries, including Kuwait. Currently, adiposity is most commonly assessed from simple anthropometric measurements, e.g. height and weight or combined as body mass index (BMI). This is despite these surrogate measurements being poor indices of adiposity. Bioelectrical impedance analysis (BIA) is a popular method for the assessment of body composition providing a measurement of adiposity as absolute fat mass (FM) or FM expressed as a percentage of body weight (%BF). BIA is, however, an indirect predictive method. This study developed a BIA-based prediction equation for body composition assessment in Kuwaiti children and, additionally, a prediction equation for %BF based on sum of skin-fold (SSF) thickness measurements.
Design:
A cross-sectional design was used with primary school recruitment.
Setting:
School population in Kuwait City; in-clinic assessments.
Participants:
158 Kuwaiti children aged 7–9 years. Body composition assessed using bioimpedance spectroscopy and skin-folds with prediction equations generate against deuterium dilution measurement of total body water and fat-free mass (FFM) as reference.
Results:
The newly developed and cross-validated BIA equation predicted FFM with minimal bias (< 1%) and acceptable 2 sd limits of agreement (±1·6 kg equivalent to ±10%) improving on the predictive performance of comparable published equations. Similarly, SSF predicted %BF with small bias (0·2 %BF) but relatively wide limits of agreement (±7 %BF).
Conclusions:
These new equations are suitable for practical use for nutritional assessment in Kuwaiti children, particularly in epidemiological or public health settings although their applicability in other populations requires further research.
Understanding country-level nutrition intake is crucial to global nutritional policies that aim to reduce disparities and relevant disease burdens. Still, there are limited numbers of studies using clustering techniques to analyse the recent Global Dietary Database (GDD). This study aims to extend an existing multivariate time series (MTS) clustering algorithm to allow for greater customisability and provide the first cluster analysis of the GDD to explore temporal trends in country-level nutrition profiles (1990–2018).
Design:
Trends in sugar-sweetened beverage intake and nutritional deficiency were explored using the newly developed programme ‘MTSclust’. Time series clustering algorithms are different from simple clustering approaches in their ability to appreciate temporal elements.
Setting:
Nutritional and demographical data from 176 countries were analysed from the GDD.
Participants:
Population representative samples of the 176 in the GDD.
Results:
In a three-class test specific to the domain, the MTSclust programme achieved a mean accuracy of 71·5 % (adjusted Rand Index [ARI] = 0·381) while the mean accuracy of a popular algorithm, DTWclust, was 58 % (ARI = 0·224). The clustering of nutritional deficiency and sugar-sweetened beverage intake identified several common trends among countries and found that these did not change by demographics. MTS clustering demonstrated a global convergence towards a Western diet.
Conclusion:
While global nutrition trends are associated with geography, demographic variables such as sex and age are less influential to the trends of certain nutrition intake. The literature could be further supplemented by applying outcome-guided methods to explore how these trends link to disease burdens.
Increased out-of-home consumption may elevate sodium (Na) intake, but self-reported dietary assessments limit evidence. This study explored associations between neighbourhood exposure to fast-food and sit-down restaurants and estimated 24-hour urinary Na excretion.
Design:
A cross-sectional analysis from the ORISCAV-LUX 2 study (2016–2017). 24-hour urinary Na was estimated from a morning spot urine sample using the INTERSALT formula. Spatial access to fast-food and sit-down restaurants was derived from GIS data around participants’ addresses within 800-m and 1000-m road network buffers by summing up the inverse of the road network distance between their residential address and all restaurants within the corresponding buffer size. Multi-adjusted linear models were used to assess the association between spatial access to restaurants and estimated 24-hour urinary Na excretion.
Setting:
Luxembourg
Participants:
Urban adults age over 18 years (n 464).
Results:
Fast-food and sit-down restaurants accounted for 58·5 % of total food outlets. Mean 24-hour urinary Na excretion was 3564 mg/d for men and 2493 mg/d for women. Health-conscious eating habits moderated associations between spatial access to fast-food and sit-down restaurants and Na excretion. For participants who did not attach great importance to having a balanced diet, greater spatial access to restaurants, combining both density and accessibility, was associated with increased urinary Na excretion at 800 m (βhighvslow = 259, 95 % CI: 47, 488) and 1000 m (βhighvslow = 270, 95 % CI: 21, 520).
Conclusions:
Neighbourhood exposure to fast-food and sit-down restaurants influences Na intake, especially among individuals with less health-conscious eating habits, potentially exacerbating diet-related health disparities.
Adolescent girls are vulnerable and deserve the utmost attention to complement their nutrition. This scoping review endeavours to identify the determinants of malnutrition among adolescent girls in Pakistan and to comprehend the interventions to improve their health and nutritional status. This review of the literature was conducted using Google Scholar, PubMed/Medline, Scopus and Web of Science for articles published between 2015 and 2024. MeSH terms used for search were as follows: adolescent, youth, health, malnutrition, nutrition interventions, systems approach. In addition, reports from the WHO, the UN, the World Bank, the Government of Pakistan and other organisations were also critically reviewed. Moreover, this paper has used the Pathways framework, which advocates multi-sectoral approaches for poverty reduction. In most developing countries, the compromised nutritional status of adolescent girls, compounded by poverty, has life-long health and economic consequences, as well as their infants having nutritional deficits. They are expected to grow as stunted children. Abundant evidence has shown that nutrition-sensitive and nutrition-specific interventions can improve their nutritional status and that of subsequent generations. There is a dire need to involve key stakeholders from health, education, nutrition, population, women’s development, social welfare and other relevant sectors. It is imperative to design interventions for adolescent girls in each country’s context to break the intergenerational cycle of malnutrition and to improve economic productivity. Political commitment and effective governance along with policy coherence are required for their healthy transitions into adulthood.
The Food Quality Observatory synthetises the nutritional composition of fifteen processed food categories commonly purchased in Québec (Canada). We assessed how the new Canadian front-of-pack (FoP) labelling regulation of a ‘high in’ symbol, to be implemented as of January 1, 2026, would be potentially reflected in these categories and how simulations of reformulation would impact the presence of the symbol.
Design:
Nutritional information was obtained by collecting food products available in supermarkets and grocery stores in the province of Québec (2016–2022). Sales data were obtained from NielsenIQ company. Fifteen food categories have been selected, and three levels of reformulation were simulated.
Setting:
The nutritional values of 5132 products were merged with sales data. 3941 products were successfully cross-referenced.
Results:
Sixty percent of all products sold (n 2336/3941) would carry the ‘high in’ symbol reflecting a high content of Na, saturated fat and/or total sugar (39 %, 16 % and 17 %, respectively). For certain food categories, a slight reduction (5–15 %) in Na, saturated fat or total sugar content would allow removing the ‘high in’ symbol in a large number of products. For example, a 5 % reduction of the Na content in sliced breads would allow 22 percentage point (pp) fewer products to display the symbol.
Conclusions:
This study presents a portrait of processed foods purchased in Québec (Canada) and the distribution of the FOP ‘high in’ symbol. Such a portrait generates important data to monitor the food supply’s nutritional quality, which can ultimately contribute to improving the nutritional quality of processed foods.
The concept of the protein transition represents a shift from a diet rich in animal proteins to one richer in plant-based alternatives, largely in response to environmental sustainability concerns. However, a simple swap by replacing dairy protein with plant protein will lead to lower protein quality and a lower intake of key micronutrients that sit naturally within the dairy matrix. Owing to antagonistic effects within the plant food matrix, micronutrients in plant sources exhibit lower bioavailability which is not reflected in food composition data or dietary guidelines. The dairy matrix effect includes moderation of blood lipid levels in which calcium plays a key role. Protein recommendations often take a muscle-centric approach. Hence, strategies to increase the anabolic potential of plant proteins have focused on increasing total protein intake to counter the suboptimal amino acid composition relative to dairy protein or leucine fortification. However, emerging evidence indicates a role for nutrient interactions and non-nutrient components (milk exosomes, bioactive peptides) of the dairy matrix in modulating postprandial muscle protein synthesis rates. To ensure the food system transformation is environmentally sustainable and optimal from a nutrition perspective, consideration needs to be given to complementary benefits of different food matrices and the holistic evaluation of foods in the protein transition. This narrative review critically examines the role of dairy in the protein transition, emphasising the importance of the food matrix in nutrient bioavailability and muscle health. By considering both nutritional and sustainability perspectives, we provide a holistic evaluation of dairy’s contribution within evolving dietary patterns.
To map out evidence on instruments for evaluating organisational food environments of workplaces and the components and dimensions considered in the identified instruments.
Design:
A scoping review that includes studies published as of January 2005, the year of publication of the model developed by Glanz et al. (2005). The databases consulted were PubMed, Embase, Web of Science, PsycINFO, Scopus and Google Scholar until November 2024, without language restrictions. Studies were included if they evaluated the food environment of workplaces such as companies/factories, universities/post-secondary institutions/technical colleges and hospitals/health care units. The conceptual model of Castro and Canella (2022), considering its components and dimensions, was used to synthesise the data.
Results:
After a full reading, fifty-four articles were selected. Most were conducted in the United States and Brazil, although there were studies from sixteen countries. A total of thirty-six instruments were identified: nineteen were used in universities, eight in hospitals, and eleven in companies. No instrument included all components and dimensions of the conceptual model; however, three instruments included most of them. The most evaluated component was the internal level of eating spaces, and the most evaluated dimensions were the availability and quality of foods/beverages in eating spaces. Of the thirty-six instruments, twenty-nine reported some measure of validity or reproducibility. The limitation most reported by the studies was the non-generaliation of results because samples are limited.
Conclusions:
Evaluations of the organisational food environment of workplaces can be used for monitoring, planning interventions and formulating public policies for such places, thereby enhancing workers’ health.
While the traditional Japanese diet has been suggested to increase blood pressure due to its high Na content, whether the contemporary Japanese diet is associated with blood pressure remains elusive. We developed a traditional Japanese diet score (nine items: white rice, miso soup, soy products, vegetables, mushrooms, seaweeds, fish, salty food and green tea) and a modified version by substituting white rice with whole-grain rice, reverse scoring for salty food and adding fruits, raw vegetables and dairy products using data from 12 213 employees from Japanese companies. Hypertension was defined as a blood pressure of 140/90 mmHg or more or the use of antihypertensive drugs. A multi-level Poisson regression model with a robust variance estimator was used to calculate prevalence ratios (PR) and 95 % CI while adjusting for covariates. The adjusted PR (95 % CI) of hypertension for the lowest through highest quartiles of the traditional Japanese diet score were 1·00 (reference), 0·94 (0·88, 1·02), 0·98 (0·90, 1·06) and 0·96 (0·90, 1·02), respectively (P for trend = 0·29), while those for the modified Japanese diet score were 1·00 (reference), 0·96 (0·94, 0·99), 0·95 (0·85, 1·05) and 0·94 (0·87, 1·01), respectively (P for trend = 0·10). In this cross-sectional study, close adherence to the traditional Japanese diet was not associated with the prevalence of hypertension, whereas there was a suggestion of an inverse association between the modified Japanese diet and the prevalence of hypertension.
To explore the information available in school food purchase data and ascertain the potential to assess pupils’ dietary intakes. The proportion of purchased food and drink items that were linked to (i) an Intake24 food group and (ii) a nutrient code from the UK National Diet and Nutrition Survey (NDNS) Databank was calculated.
Design:
Pupil-level food purchase data covering the whole school day were obtained. Each item purchased was linked to an Intake24 food group and an NDNS Nutrient Databank code. Depending on the level of detail provided, items may have been assigned both a food group and a nutrient code, a food group only or neither for items, which did not contain enough information about the type of food or drink purchased.
Setting:
Five secondary schools in northeast England.
Participants:
Secondary school pupils aged 11–16 years.
Results:
The data captured 119 125 purchases made by 3466 pupils. 92 % of item descriptions were assigned a food group, and this equated to 82 % of total purchases. 70 % were assigned an NDNS Databank nutrient code, which accounted for 60 % of total purchases. 8 % of items had insufficient information and did not have a food group or a nutrient code assigned.
Conclusions:
The methodological challenges of collecting dietary data from pupils in the secondary school setting are significant. Purchase data offers an alternative, objective approach to collecting information on school food choices across the school day and for a large sample of pupils. With further development, the potential to use purchase data to assess intakes could be achieved.
We evaluated the impact of an established nutrition education intervention, ‘PhunkyFoods’ on food literacy, cooking skills and fruit and vegetable intake in primary school aged children.
Design:
A pre-registered cluster randomised controlled trial was used; the intervention group received the ‘PhunkyFoods’ programme and the wait-list control group received the usual school curriculum. Primary outcomes measured were differences in food literacy and cooking skills scores between the intervention and control arms after 12 months adjusted for baseline values.
Setting:
The trial was undertaken in twenty-six primary schools in North Yorkshire, UK.
Participants:
631 children aged 6–9 years participated (intervention n 307, control n 324) through assemblies, classroom activities and after-school clubs.
Results:
There were no significant effects of the intervention compared with control on food literacy, cooking skills, vegetable intake or fruit intake. Adjusting for baseline, the Food Literacy Total Score was 1·13 points lower in the intervention group than the control (95 % CI –2·87, 0·62, P = 0·2). The Cooking Skills Total Score was 0·86 lower in the intervention group compared with the control (95 % CI = –5·17, 3·45, P = 0·69). Girls scored 2·8 points higher than boys in cooking skills across the sample (95 % CI = 0·88, 4·82, P < 0·01).
Conclusion:
The intervention did not result in improved food literacy or cooking skills, though sex effects on these outcomes were observed. More practical food preparation hours are needed in primary schools to improve the likelihood of an effect on outcomes.