In this retrospective case series, we present two patients with primary lateral sclerosis (PLS) and spasticity-related gait impairment. Both patients were assessed with 6-min walk tests (6MWT) and timed up and go (TUG) at baseline and after 4 weeks of oral levetiracetam. Following levetiracetam therapy, Patient 1 improved 27.3% (148.5 to 189 m) on 6MWT and 26.1% (23–17 s) on TUG. Patient 2 improved 18% (90 m in 4:29 min to 112 m in 6 min) on 6MWT and 10% (46–41 s) on TUG. Larger prospective trials of levetiracetam for spasticity and gait may be considered in PLS.

The burden of cancer worldwide is rising, with 20 million new cases diagnosed in 2022. In Europe, 1.2 million women are diagnosed with cancer annually and an estimated 600,000 women die from cancer each year. International research and data from Ireland demonstrate that women with cancer face a particular set of challenges, including increased psychological distress compared to men. As a result, Ireland’s Model of Care for Psycho-Oncology could usefully place greater emphasis on gender-specific provisions which address the increased psychological needs of women. To date, Ireland has made some progress in recognising the physical and mental healthcare needs of women and developing gender-informed policies. It is essential that such policies are implemented fully so as to reduce and eliminate disparities in care. A more tailored, gender-informed approach would also help ensure the provision of gender-aware psycho-oncological care for all women and men as they navigate their cancer journeys.

This study provides the large-scale bibliometric assessment of the Journal of Management & Organization (JMO), offering insights into its intellectual trajectory and positioning within the management field. Covering 1,083 documents published between 1995 and 2024, indexed in Web of Science and Scopus, the analysis applies performance metrics, citation structures, and science mapping using VOSviewer and Bibliometrix. The study is further grounded in institutional and field-theoretic perspectives, interpreting JMO’s evolution as a process of legitimacy-building and scientific capital accumulation within a global knowledge field. The results show that JMO’s growth has been marked by cyclical expansion, with a sharp increase in productivity since the mid-2000s but uneven citation impact, heavily reliant on a small set of landmark articles. Co-citation and bibliographic coupling analyses reveal intellectual roots in organizational behavior, psychology, and strategy, while keyword and thematic mapping highlight enduring strengths in leadership, human resource management, and job satisfaction. At the same time, new research frontiers have emerged in governance, innovation, sustainability, and work-life balance, reflecting JMO’s responsiveness to global challenges such as COVID-19 and digital transformation. Collaboration networks confirm the journal’s Australasian anchoring, yet also demonstrate growing integration into international research systems, particularly through linkages with the United States, China, and Europe. This study contributes to understanding JMO’s evolving role within management and organizational scholarship, identifying both its achievements and challenges. The findings offer insights for scholars, institutions, and editors on how JMO can consolidate high-impact niches, diversify its author base, and strengthen its influence in shaping global management debates.

The Ketton Mosaic depicts the duel between Achilles and Hector, the dragging of Hector’s body and its ransom. Despite initial associations with the Iliad in the press, this article demonstrates that the Ketton mosaic does not illustrate scenes from Homer but an alternative variant of the narrative which originated with Aeschylus and remained popular in Late Antiquity. The composition also reveals its debt to a pattern repertoire shared by artists working in media such as painted pottery, coin dies and silverware, which had been circulating in the ancient Mediterranean for many centuries. Through its textual and visual allusions, the Ketton mosaic makes a strong case for the engagement of fourth-century Roman Britain with the cultural currency of the wider empire.

This article investigates the organization of a transnational criminal enterprise through a detailed case study of Operation Singapore, a network producing and trafficking falsified pharmaceuticals from China to the United Kingdom. Drawing on law enforcement records, court transcripts, digital communications, and expert interviews, the study maps the structure and strategies of this criminal enterprise. It applies Peter Reuter’s theory of criminal organization, and Niles Breuer and Federico Varese’s typology of network forms to show how functional roles shape organizational structure: production was hierarchical and security-driven, while distribution was decentralized and transactional. Trust was not based on kinship or ethnicity but constructed through moral appeals and restricted information flows. The case reveals how criminal actors exploit legal frameworks and commercial infrastructures to mask illegal activity and blur boundaries between legal and illegal markets. These findings challenge static models of organized crime and call for a more dynamic, relational understanding of criminal enterprise.

In a propensity-matched cohort of adult cardiac or neurosurgical procedures (n = 1,342), infection was less frequent with continuous infusion (1.8%) versus intermittent cefazolin (2.4%), though the difference was statistically non-significant (−0.6%, 95% CI−2.3 to 1.1; p = 0.57). The 0% infection rate among cardiac cases receiving continuous cefazolin infusion warrants further investigation.

Analysis of the projectile points from the Arroyo Seco 2 site allows us to evaluate their design and use from the Early to the Late Holocene in the Pampas region. The Arroyo Seco 2 projectile points are associated with events of interpersonal violence as well as hunting. Based on the techno-morphological and typological analysis and the interpretation of weapon systems, it enables us to establish differences and similarities of several point designs. The results are integrated with projectile point information from other sites in the eastern Pampas to develop a chronological sequence from the Late Pleistocene through the Holocene of projectile designs that were used throughout the period.

Shmuel Nili’s Beyond the Law’s Reach? is an inquiry into the moral duties of the world’s established democracies in a world rife with violent and undemocratic states. Nili argues that these “consolidated” democratic states are “entangled” with the leaders of such violent polities—and uses this entanglement to derive an elegant and plausible series of political duties. In response, this essay seeks to undermine the distinction between the established democracies and the violent states, by showing that some democratic states—including, most centrally, the United States—are as violent as those societies considered by Nili as the focus of international moral obligation. This fact, however, does not impugn the moral obligations identified by Nili; instead, it demonstrates that Nili’s duties might demand something like a necessary form of moral hypocrisy—in which a democratic state might be effectively able to undermine violence abroad, even while incapable of effectively eliminating that violence on its own territory.

In this paper, we prove the integrality conjecture for quotient stacks arising from weakly symmetric representations of reductive groups. Our main result is a decomposition of the cohomology of the stack into finite-dimensional components indexed by some equivalence classes of cocharacters of a maximal torus. This decomposition enables the definition of new enumerative invariants associated with the stack, which we begin to explore.

As emerging markets rise, some incumbent firms that once occupied follower positions are now striving for industry leadership, surpassing competitors to become new frontrunners. These firms must overcome both competitive barriers and organizational identity (OI) challenges, constructing a leading organizational identity (LOI) that aligns with their new roles. This study delves into these transformations through the temporality lens of OI, using a comparative analysis of two Chinese firms, and identifies two distinct modes: progressive evolution and radical change. The progressive evolution mode adopts a more gradual, layer-by-layer iterative transition, whereas the radical change mode follows a ‘break and (re)build’ logic to identity structure. Both modes demonstrate a ripple effect of OI’s three structural layers, radiating outward from the core. Temporal dynamics play a pivotal role: the progressive evolution mode aligns with a more stable environment and a future-oriented, long-term temporal perspective, while the radical change mode is linked to a dynamic, unstable environment and a past-oriented, short- and long- term interactive temporal pattern. This study highlights how temporal orientation and temporal horizon shape the construction of an LOI, advancing research on OI construction and its temporal dynamics while providing insights into high-position leaps in emerging markets.

The use of ultrafiltration remains a subject of ongoing debate among pretreatment methods employed in radiocarbon dating of mammalian archaeological bone. However, such discourse had not previously extended to the archaeology of the Canary Islands (Spain), where detailed descriptions of laboratory processing methods for collagen purification often remain absent. Our study presents a case study involving a new set of radiocarbon dates obtained from the remains of ancient natives of Tenerife Island. For the first time in this region, we compared the results of ultrafiltered with non-ultrafiltered collagen from the same individuals, focusing on the method’s implications for dating accuracy in the Canaries. Through an examination of the cleaning protocols of ultrafilters and an assessment of the reliability of radiocarbon dating outcomes, we have found that ultrafiltration may influence the accuracy of results. However, given the additional handling required and the potential risk of contaminating the samples, its application should be carefully considered. In the context of the Canary Islands, ultrafiltration may be most relevant for samples associated with early human occupation, though further research is needed to assess its necessity across different biogeographical contexts. This communication further contributes to a broader understanding of preparation methods for radiocarbon dating bone from various environmental contexts, emphasizing the uniqueness of each case. Furthermore, we discuss the implications of our findings for archaeological research in the Canary Islands, highlighting the methodological gaps that persist in the region and underscoring the importance of ensuring the accuracy and reliability of chronological interpretations in archaeological investigations.

In Beyond the Law’s Reach? Shmuel Nili examines the moral responsibilities of affluent democracies toward poorer countries to whose misfortunes they contributed. Because of their entanglement, Nili argues, affluent democracies are (often, but not always) morally barred from pursuing policies more obviously aligned with their moral preferences when another policy would benefit the weakened state more. In this essay, I discuss some of the challenges of trying to repay a moral debt between states. The affluent democracy has incentives to underestimate the extent of its moral debt, while the weakened state benefits from overestimating the harm it suffered. Moreover, since the state is not a unitary actor, different members of a state might disagree on which actions should count as proper forms of atonement. I argue that moral debts cannot ever be fully repaid, but that such impossibility does not undermine the moral requirement to try to pay them; and, further, that the inability to fully settle a moral debt is not a shortcoming to lament, but closer to a blessing in disguise, because acknowledging past misdeeds and embracing the moral implications of deep entanglement may foster greater reciprocity and solidarity in the international realm.

This article reinterprets Toyotomi Hideyoshi’s invasions of Korea (1592–1598) as a project of revisionist order-building undertaken by a liminal polity situated between two competing systems: the declining Ming-centered Chinese international system and the advancing Spanish–Portuguese imperial order. Rather than viewing the invasions as products of domestic consolidation, megalomania, or simple expansionism, the study situates them within Japan’s systemic dilemma of in-betweenness. From this perspective, Hideyoshi’s campaigns represented an attempt to construct a Japan-centered international system designed to assert autonomy, deter Iberian colonization, and reconfigure regional hierarchy. Drawing on the concept of liminality in international relations (IR), the paper shows how actors at the margins of overlapping systems can exercise strategic agency – not only adapting to dominant orders but seeking to create alternative ones. Hideyoshi’s vision combined elements of the Chinese international system and deterrent signaling aimed at European powers, producing a hybrid order neither Confucian nor colonial. Although the project collapsed after his death, it temporarily deterred European expansion and reshaped East Asian political dynamics. Theoretically, this case extends debates on revisionism and liminality, demonstrating that order-building from the margins can be both creative and destructive, illuminating broader dynamics of plural international orders.

In The Emperor’s New Mind [7], Roger Penrose proves a variant of the halting problem, and uses it to argue that humans have cognitive capacities beyond the computable. In this short note, I explicate his argument, and show how it fails, via a corollary of his result. My response to Penrose is in fact of a kind with a number of prior responses: he assumes human powers, that (as the corollary shows) no computer could have. However, as far as I am aware, no one has previously addressed this specific form of the argument, in the direct way that I will.