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This chapter considers neuroscience translations and attempts to apply our knowledge of the nervous system in practical approaches. I start by discussing the traditional areas of translation, neurology and psychiatry, and the extent to which a focus on neurobiological aspects can help in addressing these conditions. I then turn to more recent claims that neuroscience can inform educational practice, including claims of pharmacological cognitive enhancement, and neurocriminology claims that we will be able to predict and prevent criminal behaviour by identifying the neural mechanisms involved. The discussion covers brain imaging and heritability approaches that try to identify biological bases that can be targeted in translations and interventions, highlighting the caveats associated with these approaches and the claims made from them.
Consultation-liaison psychiatry (CLP) refers to the subspecialty of psychiatry and the specialist clinical services that deliver care at the intersection of mental and physical healthcare. CLP services provide specialist medical and multidisciplinary expertise for managing conditions in these areas of mental and physical healthcare overlap, and comorbidity. The Model of Care for CLP was identified as a key priority in Sharing the Vision, the 2020 national mental health policy in Ireland. Following four years of work by a writing group initiated by the Faculty of Liaison Psychiatry at the College of Psychiatrists of Ireland, the Model of Care for CLP in Ireland was launched in May 2025 (Cpsychi H (2025). Consultation-Liaison Psychiatry: A Model of Care for Ireland. Dublin: HSE.).). Consultation-Liaison Psychiatry: A Model of Care for Ireland. Dublin: HSE.). This reflects the collaborative efforts between the Liaison Faculty and the Irish Health Service Executive (HSE). This Model of Care, developed in collaboration with clinicians and patients, the College of Psychiatrists of Ireland, and the HSE, provides a potential template for future collaborations in the development and implementation of National Mental Health policy.
Early in the SARS–CoV-2 pandemic, most jurisdictions implemented mandatory face covering policies across healthcare settings. This intervention, which lasted multiple years, was unprecedented in psychiatry. Masks may affect the delivery of mental healthcare, given its reliance on nuanced communication and establishing a therapeutic alliance.
Aims
This scoping review aimed to provide an overview of the current literature concerning the impact of face masks in mental health settings beyond infection control and identify research gaps to guide future research and policy.
Method
Systematic searches were completed in the MEDLINE, Embase, PsycINFO, Scopus and CINAHL databases on 14 August 2024. Articles were eligible if they described peer-reviewed empirical studies involving people with mental disorders or mental health clinicians that reported on impacts of face coverings.
Results
Twenty-eight studies were selected for inclusion, involving 5385 participants. There was considerable heterogeneity among studies. Negative effects of face masks were reported in 26 studies in at least one domain. Themes from the survey-based literature included face masks negatively affecting communication, the therapeutic relationship and overall assessment quality. Experimental studies using emotion recognition tasks showed that people with mental disorders were disadvantaged by masks when interpreting emotions from facial expressions. The most commonly studied population was people with autism spectrum disorder. Children and people with severe or acute mental illness were underrepresented. Only two studies expressly recruited psychiatrists.
Conclusions
Policy makers should be aware of adverse impacts of mask-wearing in mental health settings and consider these in evolving risk–benefit analyses. Further research is needed to establish the extent of impacts on population subgroups.
An account of the making of the Wooster Group’s Rumstick Road, an autobiographical inquiry into the circumstances and legacy of the suicide of Spalding Gray’s mother. (The production, in rehearsal in the fall and winter of 1976, held an open rehearsal in December before opening the following spring.) The chapter considers the Wooster Group’s approach to acting (distinct from the style of its predecessor, the Performance Group), the visual art sources for the production’s imagery and structure, the use of recording technology, the role of the spectator, and the nature of privacy.
We aimed to investigate the effects of the COVID-19 pandemic on the education and professional development, working conditions, and wellbeing of early career psychiatrists (ECPs) in Europe, as well as their attitudes to telepsychiatry.
Methods
A questionnaire comprising 24 items was designed by the Early Career Psychiatrists Committee of the European Psychiatric Association. Data were collected online from June 2020 to September 2021. A series of multiple regression analyses were conducted to determine variables that could predict the dependent variables.
Results
Data were obtained from 517 early career psychiatrists from 39 different countries. Men were more confident than women in their knowledge of COVID-19 symptoms and management, including in managing patients with a comorbidity of COVID-19 and a mental disorder. Providing specific recommendations during the COVID-19 pandemic, access to additional educational activities for ECPs, following COVID-19-related recommendations and access to protective equipment were the significant predictors of a higher confidence in managing patients with comorbidity of COVID-19 and mental disorders. The obligation to change the place of work predicted a decreased satisfaction with telepsychiatry as well as a decreased willingness to use telepsychiatry after the COVID-19 pandemic, while a diagnosis of COVID-19, having recommendations for telepsychiatry and access to dedicated platform for telemedicine were predictors of an increased satisfaction with telepsychiatry.
Conclusions
The COVID-19 pandemic has affected ECPs in Europe to varying degrees. The results point to areas where decision-makers can improve the working conditions for ECPs.
Developing countries (a term often used interchangeably with low- and middle-income countries) account for the overwhelming majority of the world’s population. There is a huge burden of mental illness coupled with deficits in mental healthcare resources and infrastructure that perpetuates a high treatment gap in most developing countries. Good quality scientific research can help in understanding the challenges and evaluating solutions to improve mental healthcare delivery. However, there is a substantial scarcity of research from developing countries. This chapter discusses the unique nature of strengths and challenges with respect to mental health and provides examples of successful scientific mental health research with public health implications from developing countries. The feasible solutions to improve mental healthcare research across individual, organisational, and national level in developing countries given the unique strengths and deficits are discussed in detail.
Motor functional neurological disorder (FND) is a common illness associated with significant functional impairment. There are no effective pharmacotherapies, and despite the early promise of physiotherapy studies, many suffer disabling symptoms in the long term. There is a theoretical rationale for combining psychedelics with physiotherapy; however, the potential benefit of this approach and optimal treatment model remains unexplored. Here, we present the protocol for the first study investigating the tolerability, feasibility, and potential efficacy of two distinct treatment regimens of psilocybin-assisted physiotherapy for refractory motor FND: a moderate dose that incorporates movement tasks during the acute drug effects versus a standard dose alone.
Methods:
Twenty-four participants with refractory motor FND will be randomised in a 1:1 ratio to either (1) psilocybin 15mg, with movement tasks conducted during the acute drug effects; or (2) psilocybin 25mg alone. All participants will receive two sessions of FND-specific physiotherapy pre-dosing, six sessions of physiotherapy post-dosing, and undergo follow-up visits one week and four weeks following their final physiotherapy session. A battery of outcome measures will be completed as scheduled, assessing tolerability, feasibility, motor FND symptom severity, psychiatric and physical symptoms, quality of life, treatment expectations, intensity of the acute drug effects, personality, motor function, force-matching performance, resting-state and task-based brain imaging, and subjective experiences of the study treatment.
Discussion:
These findings will assist the design of an adequately powered randomised controlled trial in this cohort. The findings may also inform the feasibility of psychedelic treatment in related functional and neuropsychiatric disorders.
To examine awareness of metabolic syndrome, lifestyle habits and attitudes towards physical health monitoring in a cohort of service users prescribed clozapine.
Methods:
A cross-sectional study, utilising chart reviews and surveys, of service users attending a clozapine clinic in Ireland, to examine awareness of metabolic syndrome, current dietary and exercise habits and attitudes towards physical health checks for metabolic syndrome was conducted.
Results:
Sixty-nine service users attending the clozapine clinic (53.1% of attendees) participated in the study of which 23 (33.3%) participants met criteria for metabolic syndrome within the previous 12 months. Nine (13.0%) participants were aware of the term “metabolic syndrome”, with six aware of what metabolic syndrome entailed. Forty-seven (68.1%) participants described their diet as “healthy”, with 17 (24.6%) participants reporting the consumption of five portions of fruit and vegetables per day on a regular basis. Thirty-eight (55.1%) participants reported engaging in ≥ 2.5 hours of exercise per week. Most participants (> 70% for all physical indices) agreed that physical health monitoring was important with 46 participants (66.7%) stating physical health monitoring should occur monthly.
Conclusion:
Although there was a limited awareness and understanding of “metabolic syndrome” in this cohort of service users prescribed clozapine, monitoring of physical health indices was acknowledged as important. Early dietary and exercise interventions in an attempt to combat high morbidity and premature mortality rates are advised for this service user cohort.
This chapter provides an overview of neurodevelopmental disorders (NDDs) in children and young people. The definition and classification of NDDs is discussed, including key differences between ICD-10 and ICD-11 and the problematic use of language in diagnostic classifications, which is at odds with the social model of disability. Important stages of a multidisciplinary assessment of NDDs include a detailed developmental history, a psychosocial history, observation of the child, an assessment of the child’s communication and learning and supplementary rating scales. The role of professionals such as Community Paediatricians, Speech and Language Therapists, Occupational Therapists, teachers and Educational Psychologists is highlighted. Features of the main NDDs are outlined, including Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Specific Disorders of Development and Language and Tic disorders. Finally, an overview of treatment approaches and their evidence base is explored.
There is a rich history of using the arts in psychiatric care, e.g. in various forms of arts therapies. A more recent development is the collaboration of the arts in psychiatric research. The arts and psychiatric research have several fundamental differences which can lead to fruitful inspiration and innovative approaches in research. The benefits include a wider engagement of individuals and non-academic groups in research, creativity in designing research approaches, a reach to societal groups that academic research usually cannot access, and the provision of real life meaning to research evidence. Two examples of such collaborations illustrate the potentials.
Off-licence psychotropic use in people with intellectual disability and/or autism, in the absence of psychiatric illness, is a major public health concern in England.
Aims
To ascertain and compare views of psychiatrists and non-psychiatrists working with people with intellectual disability and/or autism on psychotropic medication optimisation for this population.
Method
A cross-sectional survey of 13 questions was disseminated online among psychiatrists and other health professionals working with people with intellectual disability and/or autism across England, using a non-discriminatory exponential snowballing technique leading to non-probability sampling. The questionnaire covered demographic characteristics, perceived barriers/benefits of psychotropic optimisation (including ethnicity) and views on implementation of a national medicine optimisation programme. Quantitative analysis used chi-squared, Mann–Whitney and unpaired t-tests, with significance taken as P < 0.05. Thematic analysis of free-text responses was undertaken with Braun and Clarke’s methodology.
Results
Of 219 respondents, significant differences in attitudes to most issues emerged between psychiatrists (n = 66) and non-psychiatrists (n = 149). Psychiatrists had less optimism of a successful national medication optimisation programme if commissioned, or achieving 50% reduction in psychotropic overprescribing and inappropriate psychotropic prescribing generally. Perceived barriers to reducing overmedication differed significantly between the psychiatrists and non-psychiatrists, Thematic analysis identified five themes (system issues, resources, medication challenges, family and carers, and training and alternatives/structure).
Conclusions
This is the first study to highlight important differences between psychiatrists and non-psychiatrists’ attitudes to psychotropic optimisation despite respondents overall being broadly supportive of its need. A major finding is the hitherto unquantified concerns of patient ethnicity and its impact on psychotropic optimisation principles.
To triangulate the perspectives of mental health clinicians, older people with mental illness and their carers on Advance Care Planning (ACP) to develop evidence-informed educational resources.
Methods
The study setting was public mental health services. Results of previously reported reflexive thematic analyses of interviews discussing ACP with three stakeholder groups (12 older people with mental illness, 5 carers, and 15 mental health clinicians) were triangulated. The emergent overarching themes were considered within an interpretive description framework to develop educational resources to support each of the three stakeholder groups to engage in ACP.
Results
Four overarching themes emerged: (i) importance of ACP recognized but ACP often not initiated; (ii) knowledge gaps; (iii) skill gaps – how to do it; and (iv) practical and process issues. Taking into account the research team’s knowledge of the local health contexts, two formats of educational resources were developed; written information sheets bespoke to identified knowledge gaps and needs for each group, and brief training films for clinicians addressing need for practical skills in ACP. The consumer and carer sheets were translated into three languages. Two brief clinician training films demonstrated introducing ACP within mental health reviews and how to address aspects of complexity in ACP with older adults with a mental illness and carers.
Significance of results
The current absence of specific educational resources for ACP with older people with mental illness contrasts with the recognized importance of ACP. Written resources were created to address empirically identified knowledge gaps and misconceptions and provide practical information and training films developed to demonstrate key skills for clinicians. The resources were made freely available, with dissemination planned to promote and evaluate use as part of a more comprehensive educational intervention. Resources supporting clinician, consumer and carer education are an important first step towards empowerment and participation in ACP.
How do legal and medical professionals construct patients’ legal status and mental states in courtrooms, and how do patients themselves shape those constructions? This paper analyzes 300 hearings in Paris and New York City where people who have been involuntarily hospitalized in psychiatric facilities ask to be released. In both cities, courts reject the vast majority of requests. They do so by drawing on the two systems’ distinctive legal repertoires and control capacity to make patients into different kinds of serviceable subjects: people whose rights are given nominal consideration in the courtroom, but who are nonetheless classified as needing the forced interventions that the psychiatric system has the resources to provide. In Paris, legal professionals emphasize procedural rights while deferring to medical evaluations of patients’ consent, defined as their underlying willingness to accept long-term treatment. In New York, lawyers challenge psychiatric expertise but bargain with doctors and patients over compliance, understood as a short-term acceptance of medication. This paper reorients attention from the self-governing subjects that hybrid medical-legal-welfare interventions claim to ultimately produce toward the more contingent and situational serviceable subjects that allow for ongoing professional collaboration and institutional processing in contexts of diminished resources and expanded patients’ rights.
Involuntary placement and treatment within mental healthcare represent one of the most sensitive areas where clinical needs and human rights intersect and the protection of fundamental rights of individuals subjected to coercive measures remains a paramount concern. This issue has been along-standing interest of the European Psychiatric Association (EPA), reflected in studies conducted by the EPA members and by the EPA Code of Ethics. Moreover, the EPA supports the work of the Parliamentary Assembly of the Council of Europe on a Draft Additional Protocol to the Convention on Human Rights and Biomedicine, as an European document aiming to harmonize practice across Europe, emphasizing involuntary treatment as a last resort, guaranteeing access to legal counsel, and ensuring continuous monitoring. However, weemphasize several aspects that should be included: 1) future reforms must integrate legalsafeguards with innovations in community care and evidence-based practice, ensuring that involuntary measures remain exceptional and rigorously justified; 2) while evidence-based strategies to reduce coercive treatment exist, it is important to emphasize the need for regular staff training, knowledge exchange, and consistent application of high standards, with a focus on minimizing the use of involuntary treatment within facilities while developing alternatives; 3)coercive treatment is regularly used in general hospitals for patients lacking decision-making capacity. Addressing all involuntary treatment, in both psychiatric and other healthcare settings, to ensure that the same legal, ethical and clinical values and standards are applied to all, is also critical in order to confine coercion to the absolute minimum.
Two years on from the implementation of the Assisted Decision-Making (Capacity) Act (ADMCA) 2015, significant legal uncertainty persists in Ireland’s acute hospitals for the care of people who lack capacity to consent to treatment. Consultation-liaison psychiatrists must navigate a legal landscape where clear lacunae have emerged in the regulation of frequently encountered clinical scenarios. We identify three of these – eating disorders requiring refeeding, refusal of life-saving treatment, and unsafe discharges – where neither the ADMCA nor the Mental Health Act 2001 provide legal authority to intervene. In such cases, the Inherent Jurisdiction of the High Court has become the default mechanism for authorising treatment or deprivation of liberty, raising serious concerns about proportionality, clinical delays and uncertainty, cost, and consistency. We also consider a fourth category of patients who require immediate life-saving treatment, and the legal status of Advance Healthcare Directives in this context. Many of the patients who fall into these categories will have an established or suspected mental illness requiring the clinical input of a consultation-liaison psychiatry team.
We contrast Ireland’s evolving capacity legislation with developments in England and Wales. Reflecting on these comparisons, we consider the proposed Protection of Liberty Safeguards may provide some clarification but also contain potential risks of becoming unwieldy and bureaucratic and still fail to provide a workable statutory basis for authorising medical treatment in acute hospital settings. A proportionate, patient-centred, and clinically usable legal framework remains urgently needed.
Mental health disorders, including depression and anxiety, pose significant public health challenges globally, and in Saudi Arabia. Despite this, psychiatry suffers from a critical shortage of specialists. This study investigates factors influencing medical students’ career decisions in regard to psychiatry, aiming to enhance understanding of, and address workforce deficiencies in, mental healthcare.
Aims
This study aims to investigate the factors influencing medical students’ decision to choose psychiatry as a future career.
Method
This cross-sectional study conducted an online survey among Saudi Arabian medical students from 28 December 2023 to 28 April 2024, employing validated questions refined through pilot testing. Participant selection included male and female students across preclinical and clinical stages, excluding non-medical students and those outside Saudi Arabia.
Result
This study explores the perceptions and interest of 430 medical students in Saudi Arabia regarding psychiatry as a career. The majority were female (69.3%), with most in their preclinical years (60.2%). Key findings include limited personal connections to psychiatry (9.5% with a family psychiatrist), and primarily influenced by medical school (55.3%) and social media (42.1%). While 65.1% perceive psychiatry as mentally demanding, uncertainties exist about career prospects and stigma persists (39.1%). Gender differences were observed, with more females (34.6%) than males (22.7%) interested in psychiatry (P = 0.014). Early inspiration in medical education significantly increased interest (P = 0.001).
Conclusion
Early exposure, personal connections and gender-specific factors significantly influence medical students’ interest in psychiatry as a career. Integrating psychiatry education early in medical curricula and addressing stigma are critical for fostering positive perceptions and attracting diverse students to the field.
Patient and public involvement (PPI) increasingly features in the shaping, design, and conduct of mental health research. This review identifies and synthesizes evidence of barriers and facilitators of PPI in mental health research within university settings. The search strategy followed PRISMA guidance and involved keyword searches in eight peer reviewed databases, grey literature, hand searching two journals, requests to national mental health organizations, and backwards and forwards citation searching. We included primary mental health studies on patient and public involvement, with data on facilitators and barriers. Data were extracted capturing author, date and country of publication, study aim, participant and research team composition, data collection and analysis methods, and levels of PPI. Quality appraisal was conducted using the CASP Checklist for Qualitative Research, with an additional item on intersectionality. We conducted an inductive thematic analysis, before holding a peer-debriefing session with a lived experience working group. The final dataset included 51 articles that were either of a qualitative design or contained analyzed qualitative data. Barriers and facilitators were grouped around the following themes: the structure of the research environment, organizational culture, and individual needs. Good practice exists, but the wider research environment and power imbalances within universities constrain PPI. For PPI in mental health research to reach its full potential, the redistribution of power, building capacity for all, the provision of safe working environments, and widening inclusion in the research process are necessary. This review involved researchers with lived experience of mental ill health.
Based on promising preliminary results from clinical trials, it seems likely that psychedelic substances (classic serotonergic psychedelics, such as psilocybin, and entactogens, such as MDMA) will be introduced into psychiatry as psychedelic-assisted therapy. This also raises a range of ethical questions that urgently need to be addressed before widespread roll-out in society. This scoping review fills a gap in the literature by providing an overview of these ethical issues using a systematic search, presentation, and descriptive analysis of ethical issues in psychedelic-assisted treatments. It includes peer-reviewed studies pertaining to human study participants and psychiatric patients (population), which discuss ethical issues (concept) of psychedelic treatments (context) in clinical trials and other clinical applications. The systematic search included several databases: MEDLINE, PsycInfo, CINAHL, HeinOnline, and PsycArticles. The search strategy, including all identified keywords and index terms, was adapted for each included database. The search was completed in June 2025 and studies published until then in any language were included. After an iterative process of inductive and deductive coding of ethical issues, the scoping review comprises seven themes related to the ethics of psychedelic-assisted treatments: (1) safety and patient well-being, (2) therapeutic relationships, (3) informed consent, (4) equity and access, (5) research ethics, (6) special contexts, and (7) societal and cultural implications. The results can be used to inform and stimulate further discussion and in-depth research on the ethics of psychedelic-assisted treatments, possibly leading to more nuanced debate surrounding a safer and more ethical implementation of psychedelic-assisted treatments in the future.
This revision guide is an invaluable resource for psychiatric trainees preparing for exams. With 55 case vignettes and over 200 topical multiple-choice questions (MCQs), the content covers a broad spectrum of relevant psychiatric disorders, including schizophrenia, anorexia nervosa, addiction, and gender dysphoria. Case vignettes provide a focused discussion of each disorder, while strategically placed topical MCQs consolidate learning and highlight concepts across disorders. Recurring features are included at the end of each chapter, including 'Exam Essentials,' which highlight the most crucial information students should remember, 'Clinical Pearls', which provide tips for practical application, and the 'Diving Deep' section allows interested students to explore specific concepts further. An engaging and comprehensive revision resource, this will be a go-to resource for MRCPsych candidates and those taking specialist examinations.
The Irish Journal of Psychological Medicine (IJPM), a journal founded with an Irish identity, has progressed over four decades into a journal of both national and international relevance. The IJPM, now the official scientific journal of the College of Psychiatrists of Ireland, works collaboratively with many stakeholders including policymakers, those working in mental health services and those who have experienced mental illness. The journal aims to publish scientific literature and research which will help service users, clinicians and mental health services, and which can inform mental health policy. In this editorial the outgoing and incoming Editors-in-Chief reflect on how the journal has developed in recent times, and how the journal can progress at a time of societal change and technological advancement.