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Self-harm and suicidal behaviours in children and young people are increasingly common. These behaviours sit on a broad continuum from relatively risk-free behaviours that may be used as coping mechanisms to life-threatening acts with suicidal intent. Self-harm is more likely in patients with co-morbid mental health conditions, but most young people who self-harm do not have a mental health diagnosis. Family adversity, educational stressors, physical health illnesses, bullying, and substance misuse may all increase the risk of self-harm. Young people may find internet support groups helpful as they may value the discretion of online support for a behaviour about which they may be embarrassed. However some internet sites teach young people more dangerous self-harming strategies and young people may be bullied or encouraged to complete suicide. Historical methods of risk stratification have poor predictive validity and it is instead recommended that clinicians engage collaboratively with young people in an individualised approach to risk assessment, developing a detailed risk formulation and safety plan. Young people who self-harm are 30 times more likely to die by suicide, and it appears that those from minority groups are at greater risk. Mild self-harm may only require a ‘listening ear’ from a trusted friend or adult, but more severe difficulties may need professional assistance from mental health services that should be trauma-informed and relational in approach, offering evidence-based interventions such as DBT-A or MBT-A. Crisis services should be responsive and flexible to young people’s needs so as to be able to engage them and de-escalate risks effectively.
Early-onset psychosis (EOP) is a severe mental disorder with a significant impact on affected children, young people and their families. Its assessment and diagnosis may be challenging, treatment approaches may not always lead to full remission of symptoms, and it is frequently associated with recurrent episodes and long-term disability. A comprehensive evaluation of psychotic symptoms, co-morbidities, physical health and environmental risk factors is likely to contribute to the holistic understanding of the child or adolescent with psychosis and provide the best possible management framework. A systematic approach to treatment with antipsychotic medication and psychosocial interventions should incorporate regular reviews of its effectiveness and adverse effects. Early intervention seems to lead to optimal outcomes through reducing the duration of untreated psychosis and providing input during the critical period after its onset when treatment can be most effective. Further research aiming to advance our understanding of the complex aetiology of psychotic disorders, effectiveness of management strategies, and necessary service provision is urgently needed.
Clinicians navigating the legislation when working with young people and their families in the United Kingdom (UK) may need to use several relevant frameworks of legislation at the same time. This may appear complex in practice. Clinicians need to consider how a young person’s development across multiple domains, for example, cognitive, emotional, moral, social and so on, can have an impact upon their decision-making. Clinicians who work with children and young people often also work with parents or their local authority statutory equivalents, as well as other statutory and non-statutory agencies, to help find the best outcomes for children and young people (CYP). This requires good knowledge of legal frameworks, competence in working within complex multi-agency systems and being able to understand and work with different perspectives around an issue.This chapter specifically discusses aspects of the law in relation to children and adolescents (all those under 18 years) including the Human Rights Framework, Mental Capacity Act 2005, Children Act 1989 (amended 2004), Mental Health Act (amended 2007), and Criminal Justice Act (2003) within England and Wales. We have not addressed the differences in legislation in Northern Ireland or Scotland but have commented on distinct issues where relevant.
Adolescence marks a critical period for the onset of anxiety disorders, yet they frequently remain undiagnosed due to barriers such as reluctance to self-disclose symptoms. Objective screening methods that bypass self-report may improve early detection. Speech-derived acoustic markers have emerged as a promising avenue for identifying anxiety disorders. This study investigates associations between acoustic properties of speech, anxiety severity, and anxiety diagnoses in adolescents, evaluated cross-sectionally and longitudinally.
Methods
Speech samples from 581 adolescents were collected during the Trier Social Stress Test. Acoustic features were extracted using OpenSMILE and analyzed for cross-sectional associations with anxiety severity (Spearman’s correlations) and longitudinal predictions of future anxiety (linear regressions). Random forest (RF) classifiers with 10-fold cross-validation were used to classify anxious and healthy individuals using acoustic features. Analyses were stratified by sex.
Results
RFs achieved the highest performance for the longitudinal classification of social anxiety disorder (SAD), with an AUC-ROC of 85% (males) and 74% (females). Adding acoustic features to baseline measures increased the variance explained in anxiety by 5.4% (males) and 10.9% (females). In males, higher anxiety was cross-sectionally correlated with reduced pitch slope, narrower pitch range, lower F1 frequency, and greater MFCC1 variability. Females with higher anxiety showed reduced variability in pitch slope. Correlations did not survive multiple testing correction.
Conclusions
Acoustic speech markers elicited in socially evaluative contexts can accurately recognize SAD in male adolescents three years in advance. Performance is moderate for females and other anxiety disorders, underscoring the need for sex-specific approaches to diagnostic tool development.
Inadequate eating habits in adolescence are an important risk factor for obesity and other chronic non-communicable diseases in adulthood. The school environment can have a relevant impact on adolescent behaviour, since many habits acquired in this phase affect the individual throughout life, with visible effects on health. In this study, we aimed to evaluate the association between food sales at Brazilian schools and ultra-processed food consumption among adolescents. The Study of Cardiovascular Risk Factors in Adolescents (ERICA) was a nationwide, school-based survey conducted from 2013 to 2014, including public and private schools in 121 Brazilian cities. Dietary intake was assessed via a 24-hour recall, and foods were divided according to the Nova Classification based on the degree of processing. Unadjusted and adjusted linear regression models were used to assess the association between exposure to school food sales and intake of ultra-processed food. The prevalence of exposure to food sales was 55.2% and the mean diet share of ultra-processed foods was 34.5%. Exposure to food sales in schools was associated with higher consumption of ultra-processed food (β=0.11; p=0.002). The results were similar when the analyses were stratified according to sex, usual intake of school meals, and public-school attendance (β=0.11; p=0.002). The association between exposure to food sales in schools and higher consumption of ultra-processed food suggests that school sales can influence adolescents’ food choices.
Severe obesity in adolescents is a public health crisis of increasing concern. Cardiac maladaptation, such as left ventricular hypertrophy, increases the risk of future cardiovascular disease. This study aims to evaluate the impact of weight loss surgery on cardiac geometry in morbidly obese adolescents.
Methods:
A single-centre, randomised controlled trial titled comparing laparoscopic adjustable gastric banding with multidisciplinary lifestyle intervention against a control group with multidisciplinary lifestyle intervention alone. The trial included severely obese adolescents aged 14–16 who had not responded to a minimum of 12 months of multidisciplinary lifestyle intervention. The primary outcome measured was the percentage change in total body weight one year after surgery. Left ventricular geometry was evaluated ultrasonographically before and one year after bariatric surgery.
Results:
In the intervention and control group, a total of 10 and 8 patients received both the baseline and follow-up ultrasonographic examination. BMI significantly decreased in the intervention group compared to the control group (−6.75; 95% CI: -10.28 – −3.23). Moreover, left ventricular mass index (−8.21; 95% CI: −15.43 – −0.98) and relative left ventricular wall thickness (−0.04; 95% CI: −0.07 – 0.00) significantly decreased within the intervention group, reflecting amelioration of adverse remodelling, albeit without statistically significant intervention effect when compared to the control group.
Conclusions:
Significant weight loss through bariatric surgery may improve left ventricular geometry in severely obese adolescents. These findings support the potential of bariatric surgery not only for reducing weight loss but also for improving cardiac health.
Regular physical activity for adults is associated with optimal appetite regulation, though little work has been performed in adolescents. To address this gap in the literature, we conducted a study examining appetite across a range of physical activity and adiposity levels in adolescent males. Healthy males (N=46, 14-18 years old) were recruited across four body weight and activity categories: normal weight/high active (n=11), normal weight/low active (n=13), overweight, obese/high active (n=14), overweight, obese/low active (n=8). Participants from each group completed a six-hour appetite assessment session on Day 0, followed immediately by a 14-day free-living physical activity and dietary assessment period on Days 1-14, and a fitness test session occurring between Days 15-18. Subjective and objective assessment of appetite, resting energy expenditure, body composition using dual energy absorptiometry‘, and thermic effect of feeding was conducted on Day 0. Physiological variables in the normal weight low active group that were different than their peers included lower fat-free mass, cardiorespiratory fitness, glucose/fullness response to a standardized meal, thermic effect of feeding in response to a standardized meal, lower self-rated fullness and satiety, and higher self-rated hunger to a standardized meal. Conversely, the overweight, obese high active group displayed better subjective appetite responses, but higher insulin responses to a standardized meal. Taken together, these results suggest that physical inactivity during adolescence has a negative impact on metabolic health and appetite control which may contribute to future weight gain.
While around one-fifth of UK secondary school pupils exhibit clinically significant eating pathology, in-school mental health provision does not include interventions to address such eating pathology.
Aims:
This preliminary qualitative study aimed to explore the views of staff, parents and pupils, on the idea of introducing a school-based brief cognitive behavioural therapy programme for non-underweight eating disorders.
Method:
31 pupils, 22 parents and 27 staff participated in 12 focus groups across four schools. The semi-structured interview guide covered topics around the practicalities of a potential eating disorders treatment programme, the acceptability of the intervention, and likelihood of future uptake.
Results:
Five over-arching themes and 12 subthemes emerged, reflecting the scale of eating and body image concerns, management limitations, and the importance of prioritising mental health over education. Advantages, challenges, considerations, and solutions were proposed for an in-school eating disorders treatment programme.
Conclusions:
These qualitative data show that there is support for an appropriately implemented in-school delivery of brief, evidence-based treatment, demonstrating the potential scope of such an approach to support children and adolescents to receive early help with their eating problems and body image concerns.
Evidence on the effects of parental Adverse Childhood Experiences (ACEs) on adolescent mental health remains limited. This study investigates the associations between parental ACEs, children’s exposure to threat- and deprivation-related ACEs, and adolescent depression and anxiety using data from the Longitudinal Study of Australian Children.
Methods
We conducted a secondary analysis of the Longitudinal Study of Australian Children (LSAC), a population-based longitudinal cohort study. Parental ACEs were retrospectively reported by caregivers. Children’s exposure to ACEs was assessed from ages 4–17 years and categorised as threat-related ACEs (e.g., bullying, hostile parenting, unsafe neighbourhoods, family violence) or deprivation-related ACEs (e.g., financial hardship, parental substance abuse, parental psychological distress, death of a family member, parental separation, parental legal problems). Depressive and anxiety symptoms were self-reported by adolescents at ages between 12 and 17 years. Modified Poisson regression models were used to examine the independent and combined associations of parental ACEs and children’s threat- and deprivation-related ACEs (assessed before ages 12, 14, and 16 years) with depression and anxiety outcomes, including tests for interaction effects.
Results
The analysis included 3,956 children aged 12–13 years, 3,357 children aged 14–15 years, and 3,089 children aged 16–17 years. Males comprised 50.8–59.8% and females 40.2–49.2% across all ages. By the age of 17, 30.4% and 9.4% of the adolescents had depression and anxiety, respectively. Parental ACEs (≥2) were associated with increased depression risk at ages 12 to 13 years (RR = 1.42; 95% CI: 1.10–1.84) and at 16–17 years (RR = 1.19; 95% CI: 1.02–1.39). Exposure to ≥ 2 deprivation-related ACEs significantly increased the risk of depression across all ages, with relative risks ranging from 1.31 to 2.18. High threat-related ACEs (≥2) were associated with increased depression risk only at 12 to 13 years (RR = 2.01; 95% CI: 1.28–3.17). No significant interactions were observed.
Conclusions
The findings reinforce the ACEs model by showing that, at the population level, early identification of children exposed to early life deprivations rooted in financial crisis or familial adversities, combined with targeted interventions for both children and parents and supportive social policies, can reduce long-term mental health risks.
Emerging reports show that personal listening device usage causes vestibular impairment. This study aims to investigate the effect of personal listening device usage on vestibular impairment.
Methods
Subjects between 13 and 25 years were recruited. Each subject underwent a personal listening device usage questionnaire and quantification of sound exposure level, followed by a series of vestibular tests. Statistical analyses were performed to identify the association between personal listening device characteristics, sound exposure level and vestibular function.
Results
A total of 131 participants were recruited, with a mean age of 20 ± 2.55 years. The mean duration of personal listening device usage per day was 5.53 ± 2.76 hours. Noise exposure from personal listening device usage was noted to cause more saccular damage in adolescents. A correlation was found between the preferred listening level, the 40-hour equivalent continuous exposure level (r = 0.406, p = 0.029) and the latency right p13 among adolescents.
Conclusion
Sound exposure levels among adolescents are higher than among young adults. Personal listening device usage resulted in saccular damage among adolescents.
Gender dysphoria is linked to various psychosocial challenges in adolescence, underscoring the need to identify and support youth experiencing gender-related distress. Although gender identity exists on a spectrum beyond the binary, no validated tool currently exists in Turkey that uses inclusive, gender-neutral language to assess it in adolescents.
Aims
This study aimed to evaluate the psychometric properties of the Turkish adaptation of the Utrecht Gender Dysphoria Scale–Gender Spectrum (UGDS-GS) among clinical- and community-based adolescents.
Method
A total of 240 participants aged 12–23 years were included. The validity of UGDS-GS was assessed through content validity and confirmatory factor analysis. Reliability was measured using Cronbachʼs alpha and test–retest intraclass correlation coefficient (ICC). A sociodemographic data form, UGDS, UGDS-GS, Rosenberg Self-Esteem Scale (RSES) and Youth Self-Report (YSR) were utilised.
Results
Findings demonstrated strong content validity, with a content validity Index of 0.69, and robust construct validity, indicated by a comparative fit index of 0.993 and a root-mean-square error of approximation of 0.071 following the exclusion of three items. UGDS-GS effectively differentiated scores across demographic groups, showing significant variances based on assigned gender and age. The scale also exhibited excellent criterion validity, evidenced by an area under the curve of 0.947 in receiver operating characteristic analysis, with high sensitivity (80%) and specificity (95.9%) at an optimal cut-off value of 42.50. With a Cronbachʼs alpha of 0.935, UGDS-GS demonstrated strong internal consistency and substantial test–receiver operating characteristic retest reliability (ICC 0.884), alongside notable but weak correlations with several RSES subscales and low to moderate correlations with YSR scores.
Conclusions
These results affirm that tUGDS-GS is valuable and reliable in assessing gender dysphoria in Turkish adolescents. Further research is warranted to improve applicability in diverse contexts and populations.
Decreased gut microbial diversity is associated with greater depression symptoms in adults. Findings on the relationship between the gut microbiome and depression or anxiety in children and adolescents are mixed, and evidence syntheses are needed. Seven databases were searched for peer-reviewed studies on the gut microbiome and internalizing symptoms, depression, or anxiety, in children and adolescents (<19 years). Random-effects meta-analyses of alpha diversity indices were performed. Youth advisors validated the research findings’ relevance to their experiences and contributed to dissemination planning. Eight studies were included, representing 2,865 participants (mean age = 11.4 years, SD = 4.3). Study designs were cross-sectional (n = 5), longitudinal (n = 2), and interventional (n = 1). No association was found between alpha or beta diversity and internalizing problems, depression, or anxiety. Increased abundance of genera within phyla Bacillota (e.g., Fusicatenibacter) and Pseudomonadota (e.g., Escherichia), along with decreased abundance of other Bacillota genera (e.g., Faecalibacterium), were associated with depression and anxiety symptoms. This review identified preliminary associations between specific bacterial taxa and depression and anxiety in children and adolescents. Larger studies using comprehensive analytical approaches are needed to explore the role of the gut microbiome in the genesis and treatment of internalizing disorders.
Child and adolescent exposure to community and school violence in Africa is pervasive, with significant longer-term consequences for mental health and life outcomes.
Aims
To synthesise research on the impact of exposure to community and school violence, in terms of mental health and adjustment outcomes. The review focuses on adolescents in countries on the African continent, summarising existing knowledge regarding the impact on mental health and adjustment outcomes of different types of violence, and the associated mediating and/or moderating factors.
Method
We used the Preferred Reporting Items for Systematic Review and Meta-Analysis protocols (PRISMA-P) to conduct a systematic narrative review (PROSPERO registration CRD42023390724). PsycInfo, MEDLINE, Global Health and Web of Science databases were searched and 36 articles were included in the review. These studies were conducted in countries within Africa among adolescents (10–19 years of age) exposed to violence in their schools and/or communities, and investigated mental health and adjustment outcomes related to violence exposure.
Results
Adolescents exposed to violence in their schools and communities have increased risk of negative outcomes in areas of psychological, social, behavioural and academic functioning that persist over time. Several mediating and/or moderating variables, such as social support, school climate and negative appraisals, were found.
Conclusions
Exposure to violence in school and the community has a significant and lasting impact on mental health and adjustment which can be exacerbated and/or ameliorated by several mediating and moderating factors. Future research will benefit from the development and evaluation of interventions that deploy early identification and of secondary prevention interventions which could mitigate effects of exposure to violence for youth in high-risk contexts and emerging economies that face additional economic challenges.
For young people with eating disorders (EDs), family-based therapy (FBT) is generally recommended as first-line treatment. Although there is an abundance of evidence demonstrating the efficacy of FBT, less than half of young people achieve full remission with this treatment. Enhanced cognitive behaviour therapy (CBT-E) is an established alternative to FBT, demonstrating effectiveness in individuals who have not achieved full remission with FBT. It is also recommended when family therapy is unacceptable, contraindicated, or ineffective. Despite some overlap – particularly in addressing maintaining factors and prioritising weight normalisation – the two treatments diverge significantly in conceptualisation of the eating disorder, proposed mechanisms of action, role of both young people and parents, and strategies and processes of therapy. These differences may contribute to one treatment being effective where the other has not, but can present challenges and difficulties for the young person, family and clinician when transitioning from FBT to CBT-E. In this paper, we provide guidance for clinicians delivering CBT-E with young people who have a history of FBT treatment. We highlight common issues encountered among this cohort, discuss how they can present a barrier to successful implementation of CBT-E, and describe solutions.
Key learning aims
(1) To learn the commonly encountered barriers to treatment when implementing CBT-E for young people who have previously engaged in FBT.
(2) To learn strategies to overcome these barriers focusing on the young person, parents and multi-disciplinary team.
The dietary inflammatory index (DII) has emerged as a promising tool associated with the development of cardiovascular risk factors. This systematic review and meta-analysis, developed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines (the protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under number CRD42022323267), aimed to synthesise observational studies that evaluated the association between the DII and indicators of body adiposity and blood pressure in children and adolescents. PubMed/MEDLINE, Embase, LILACS, CINAHL, Web of Science, Scopus and Google Scholar were searched, without time and language restrictions. The methodological quality of the studies and the certainty of the evidence were assessed using the Newcastle–Ottawa scale and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, respectively. The meta-analysis revealed that a higher DII (pro-inflammatory diet) was significantly associated with increased odds of body adiposity, as indicated by body mass index (BMI) (odds ratio [OR] = 1·62; 95% confidence interval [CI] 1·38–1·86), waist circumference (OR = 1·45; 95% CI 1·10–1·81) and the waist-to-height ratio (OR = 1·76; 95% CI 1·38–2·14) in adolescents, compared with those with a lower DII (anti-inflammatory diet). In addition, for every unit increase in the DII, there was a small but significant rise in mean BMI (β = 0·06 kg/m2). The children’s dietary inflammatory index (CDII) showed no association with cardiometabolic risk factors. There were no consistent associations between the DII or CDII and blood pressure. In conclusion, while a pro-inflammatory diet (based on the DII) is linked to body adiposity, additional longitudinal studies are needed to explore these associations, particularly regarding the CDII and blood pressure.
Despite growing evidence of the benefits of delayed school start times in adolescents, only a fraction of high schools globally – including US, Europe and Asia – have adopted later starts. The disadvantages of earlier school times for adolescents elicit primary concerns of decreased academic performance and well-being with a potential for the development of mental health conditions. In this impact paper, we discuss the current evidence and contributing mechanisms regarding insufficient sleep and circadian misalignment related to adolescent school schedules. We conclude by summarizing the obstacles to implementing later school start times and provide recommendations for policy change and potential alternatives to better promote better sleep hygiene and well-being among adolescents.
The aim of this study was to evaluate the relative validity of food and nutrient intakes estimated by a brief-type diet history questionnaire for Japanese children and adolescents (BDHQ15y) designed to assess habitual dietary intake during the previous month. A total of 432 boys and 412 girls aged 6–17 years from thirty-two prefectures in Japan completed the BDHQ15y and subsequently provided 8-day weighed dietary records (DR) on two non-consecutive days over four seasons for comparison. Among the intakes of forty-four nutrients and thirty-one food groups adjusted for energy intake using the density model, the BDHQ15y showed percentage differences in median intake of less than 10 % compared with the DR for nineteen nutrients in both sexes, as well as for eleven and seven food groups in boys and girls, respectively, indicating good agreement for key nutrients and food groups, including protein, fat, carbohydrate, dietary fibre, grains, vegetables, dairy products and sugar-sweetened beverages (SSB). The median values (25th–75th percentiles) of Spearman’s correlation coefficients in boys and girls were 0·33 (0·28–0·38) and 0·28 (0·23–0·35) for nutrients, respectively, and 0·36 (0·29–0·42) and 0·29 (0·24–0·36) for food groups, respectively. Bland–Altman plots showed wide limits of agreement, with overestimation at higher intakes for most nutrients and food groups, except SSB. In conclusion, the BDHQ15y shows promise for large-scale dietary monitoring, particularly for estimating group-level intakes of key nutrients and food groups. However, its limited ability to rank individual intakes and the variability in individual-level assessments necessitate cautious interpretation and application.
Adolescents may not necessarily have a specific mental health challenge to seek information on mental health. They may be genuinely curious on how to better understand these issues, especially when mental health is being discussed in school, among peers and with parents. The purpose of this study was to examine the frequency and factors associated with online information seeking about mental health among adolescents. A total of 702 high school students from Belgrade, Serbia, participated in the study and filled in an anonymous questionnaire about sociodemographics, digital behaviors and the Electronic Health Literacy Scale (eHEALS). The prevalence of seeking information about mental health in our study sample was 23.5% (165/702). The multivariate model showed that having a lower school performance, lower eHEALS score and browsing health blogs, social media and websites run by physicians and health institutions were independently associated with online information seeking about mental health. Additionally, searching for online information about psychoactive substances, bullying and medications was independently associated with online information seeking about mental health among adolescents. Adolescents are familiar with a variety of sources of online health information, but choose specific online platforms to read about mental health. These platforms could be utilized to promote mental well-being in high schools.
This study investigates the epidemiology of adolescent suicide in India, addressing the limited research on the subject. Data on adolescent suicide (14–17 years) by sex and state were obtained from the National Crimes Records Bureau for 2014–2019, which included acquiring unpublished data from 2016 to 2019. Crude suicide rates for the period 2014–2019 were calculated by sex and state. Rate ratios (RRs) by sex and state were also calculated to assess changes over time, comparing suicide rates from 2017–2019 to 2014–2016. Female adolescent suicide rates, which ranged between 9.04 and 8.10 per 100,000 population, were consistently higher than male adolescent suicide rates, which ranged between 8.47 and 6.24 per 100,000 population. Compared to the first half of the study period (2014–2016), adolescent suicide rates significantly increased between 2017 and 2019 among less developed states (RRs = 1.06, 95% uncertainty interval [UI] = 1.03–1.09) and among females in these states (RRs = 1.09, 95% UI = 1.05–1.14). Male suicide rates aligned with global averages, while female rates were two to six times higher than in high-income and Southeast Asian countries. Findings highlight the urgent need for comprehensive surveillance and targeted suicide prevention strategies to address this critical public health issue.