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Chapter 6 - Using Clinical Data

from Section 2 - Tools and Methodologies

Published online by Cambridge University Press:  31 October 2025

Dawn N. Albertson
Affiliation:
University of New Hampshire
Derek K. Tracy
Affiliation:
South London and Maudsley NHS Foundation Trust
Dan W. Joyce
Affiliation:
University of Liverpool
Sukhwinder S. Shergill
Affiliation:
Kent and Medway Medical School
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Summary

The traditional case register involved assembling records of people with a given condition in order to support cohort studies to describe and investigate the course of their condition and other outcomes. This old design has been resurrected and revolutionised following the widespread implementation of fully electronic healthcare records over the past few decades, providing ‘big data’ resources that are both large and very detailed. These, in turn, are being further enhanced through linkages with complementary administrative data (both health and non-health) and through natural language processing generating structured meta-data from source text fields. This chapter provides an overview of this rapidly developing research infrastructure, considering and advising on some of the challenges faced by researchers planning studies using clinical data and by those considering future resource development.

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Research Methods in Mental Health
A Comprehensive Guide
, pp. 81 - 94
Publisher: Cambridge University Press
Print publication year: 2025

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