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Pregnant women are particularly vulnerable to stress and depression, which can negatively impact birth outcomes and maternal care practices. This study aimed to investigate the prevalence and determinants of stress, depression, and common mental disorders (CMDs) among pregnant women in East Lombok, Indonesia, during the COVID-19 pandemic. This cross-sectional study was part of the Action Against Stunting Hub. Data on maternal characteristics, dietary intake, anthropometry, and biochemical status were collected. Mental health was assessed during the second and third trimesters using validated instruments, the Perceived Stress Scale (PSS-14), Edinburgh Postnatal Depression Scale (EPDS), and Self-Reporting Questionnaire (SRQ-20). The prevalence of maternal stress, depression, and CMDs was 86.3%, 26.5%, and 29.7%, respectively. CMDs were associated with iron deficiency (aOR 1.61) and not receiving government assistance (aOR 1.48). Low adherence to a healthy and diverse diet, i.e., limited intake of grains, tubers, eggs, fruits, and vegetables, was associated with increased odds of antenatal stress (aOR 1.59) and common mental disorders (aOR 1.60). For depression, significant factors included higher maternal education (aOR 2.27), low-to-moderate social support (aOR 1.72), and adherence to an unhealthy dietary pattern characterized by high sugar and fat intake (aOR 1.47). Targeted nutrition interventions, including food-based dietary recommendations (FBDR) and social safety net programs, are essential during pregnancy to support nutrient intake. In addition to addressing iron deficiency, integrated approaches that promote dietary diversity, provide government support to low-income households, and strengthen social support networks are recommended to improve maternal mental health outcomes.
The Body Image in Pregnancy Scale (BIPS; Watson et al., 2017) provides a comprehensive assessment of dissatisfaction and preoccupation with appearance and physical function, perceived sexual attractiveness, and behavioral consequences of pregnancy-related changes to physical appearance. Where other measures of body image during pregnancy typically have narrower focus, BIPS is intended to cover a wide range of common body image experiences identified in prior qualitative and quantitative studies. BIPS offers flexibility for users; it is freely available to use, either in online or in-person format, and takes approximately 5-10 minutes to complete. The measure has been validated for use in a range of languages, including English, Turkish, and German, and has good factorial structure and reliability. This chapter details this psychometric evidence, as well as providing a full list of BIPS items and instructions for scoring.
The 19-item Body Understanding Measure for Pregnancy scale (BUMPs; Kirk & Preston 2019) assesses body dissatisfaction during pregnancy. The BUMPs can be administered online and/or in-person to pregnant individuals and is free to use in any setting. This chapter first discusses the development of the BUMPs and then provides evidence of its psychometric validation. The BUMPs was developed using exploratory and confirmatory factor analyses which revealed a 3-factor structure with latent variables relating to (dis)satisfaction with appearing pregnant, concerns about weight gain, and physical burdens of pregnancy. The BUMPs is also found to be invariant across all three trimesters of pregnancy and therefore appropriate for use at all stages of pregnancy. Internal consistency reliability, test-retest reliability, convergent validity, discriminant validity, and incremental validity support the use of the BUMPs. Next, this chapter provides the BUMPs items in their entirety, instructions for administering the BUMPs to participants, the item response scale, and the scoring procedure. Information concerning a retrospective version of the BUMPs and current known translations is included. Logistics of use, such as permissions, copyright, and contact information, are provided for readers.
This Element considers pregnant women and their costumes in the staging of Shakespeare's plays. It examines the connections between a character's costume and the changing social conventions of pregnancy. It questions mid twentieth century productions' reduction and elimination of well-established visible pregnancy costumes. It considers the role played by the sexual revolution in the sixties in visible pregnancy's reinstatement. The Element focusses on the varied significance of its presence to actors and directors and explores the archives to chart this previously under-examined interaction between social conventions, costumes, and the actors who wear them.
Early life, or the neonatal period, is perhaps the most challenging time for ruminant livestock, as they adapt to the extra-uterine environment, undergo important physiological maturation, and navigate harsh ambient conditions. Maternal influences during gestation, especially energy and protein nutrition in late pregnancy, can alter many processes that affect the neonatal period. These processes include fetal growth and development, gestation length, difficulty of parturition, and maternal behavior, which interact to affect offspring vigor at birth. Moreover, colostrum and early milk production and composition are affected by gestational nutrition, and these along with the previous factors affect the neonate’s ability to obtain transfer of passive immunity, thermoregulate, perform basal metabolism, and ultimately survive to weaning. Often, the long-term effects of maternal nutrition during gestation on offspring are attributed solely to the prenatal environment, but it is critical to also consider influences of early life on later productivity and health. More research is needed to integrate these neonatal outcomes with prenatal and postnatal mechanisms as well as later ruminant livestock performance. Better understanding of the maternal environment’s effects on the neonatal period provides opportunity for improved management of ruminant livestock dams and offspring.
Despite growing research on disaster-related health impacts, pregnant individuals remain understudied. This study explores the sociodemographic characteristics of pregnant women affected by Hurricane Harvey.
Methods
A cross-sectional analysis of 4,951 pregnant individuals (511 directly impacted) was conducted to identify predictors of disrupted healthcare, financial loss, and mental health outcomes.
Results
Social and structural vulnerabilities significantly influenced disaster impact. Pregnant individuals who were foreign-born racial/ethnic minorities (16.7% non-Latinx Black, 10.2% Latinx vs. 8.3% non-Latinx White), low-income (13.0% vs. 8.0%), less educated (12.5% vs. 7.6%), reliant on public healthcare (81% vs. 33.5%), or with limited maternity care access (11.4% vs. 54.8%) were disproportionately affected (all p < 0.001). Conversely, post-disaster anxiety was more common among U.S.-born (14.8% vs. 8.0%), college-educated (19.0% vs. 9.8%), and higher-income individuals (21.2% vs. 7.9%) (all p < 0.01).
Conclusions
Disadvantaged pregnant populations face greater disruption during disasters, while those with fewer vulnerabilities may experience more prolonged anxiety.
Nutrition education plays a crucial role in improving the nutritional status of pregnant women, yet evidence of its impact in low-income settings like Ethiopia is limited. This study evaluated the effectiveness of facility-based nutrition education and counseling on pregnant women’s knowledge, dietary practices, and Fe-folic acid supplement use.
Design:
A cluster randomised controlled trial was conducted in Addis Ababa, Ethiopia, involving 683 pregnant women across twenty health centres assigned to intervention or control groups. Antenatal care providers in the intervention group received training on pregnancy nutrition and counseling, while the control group continued standard care per national guidelines. A total of 683 pregnant women were enrolled during their first and second antenatal care (ANC) visits. Mixed-effects linear regression was used to evaluate outcomes.
Study setting:
The study was conducted in Addis Ababa, Ethiopia, from August to December 2017.
Participants:
Pregnant women attending ANC follow-ups and healthcare providers working in ANC units.
Results:
The intervention group demonstrated significant improvements in knowledge, including iodised salt use (difference-in-differences (DID) 23 %), correct Fe-folic acid supplementation duration (DID 68 %) and the need for additional meals during pregnancy (DID 49·9 %). Dietary practices improved with higher dietary diversity (DID 32·3 %), increased dairy consumption (MD 1·2 v. –0·1; DID 1·2 per week) and higher Fe-folic acid supplementation (MD 4·9 v. 1·6; DID 3·2 per week).
Conclusion:
Nutrition education and counseling during ANC visits significantly improved pregnant women’s knowledge and dietary practices. Integrating and strengthening these interventions into routine ANC services could effectively enhance dietary intake and health outcomes.
This study included postpartum women who survived the earthquake that occurred on February 6, 2023, with epicenters in Kahramanmaraş, and assessed their experiences, psychosocial needs using a qualitative research method. The findings were organized under 5 key themes: “psychological processes experienced during and after the earthquake,” “experiences related to pregnancy and childbirth,” “biopsychosocial problems experienced after the earthquake,” “experiences related to s workers,” and “expectations and needs of earthquake-affected mothers.” Codes were established for women that were specific to their emotional responses following the earthquake: fear, sorrow, anxiety, difficulty in controlling anger, hopelessness, exhaustion, and inability to experience the mourning process; concerning their emotional reactions at the moment of the earthquake: extreme fear, helplessness, shock, and grief response; and regarding the traumatic effects of the earthquake: post-traumatic growth and post-traumatic stress disorder. During and after an earthquake, pregnant and postpartum women have biopsychosocial needs such as shelter, food, clothing, hygiene, support, and care, and these needs should be prioritized. Early psychological interventions should be provided to help women deal with the negative traumatic experiences they encounter during this process. Relevant institutions should create individual care-focused support systems and early intervention to deliver comprehensive care following earthquake.
Iron deficiency anemia is a major health problem worldwide. Iron is an essential micronutrient in the human body; its demand increases with fetal growth and gestation. Although it has been reported that glucose metabolism is also affected by iron deficiency, only few studies have investigated the influence of iron deficiency during gestation and in offspring. In this study, glucose metabolism in newborns was investigated in terms of maternal iron deficiency prior to pregnancy in a rat model. Briefly, rats were divided into control (CL) and iron deficiency (ID) groups. The levels of serum glucose and insulin and the protein expression of liver GLUT2 in neonates born to dams in the ID group increased. In contrast, the mRNA and protein expression levels of GLUT2 and GLUT4 in the skeletal muscle tended to decrease. In addition, the expression of p-Akt (Thr308), which is involved in GLUT4 membrane translocation, decreased, suggesting that GLUT4 translocation to the plasma membrane may not have been sufficiently promoted. These results suggest that maternal iron deficiency may influence glucose metabolism in neonates and potentially increase the risk of developing metabolic abnormalities and lifestyle-related diseases later in life.
This pilot cross-sectional study, conducted in two public hospitals in Malawi, assessed gestational diabetes mellitus (GDM) in pregnant women attending antenatal clinics and compared their dietary quality and food group consumption before and during pregnancy. The study targeted women aged 18 to 49 years within 24 to 28 weeks of gestation. GDM was diagnosed according to the International Association of Diabetes and Pregnancy Study Group criteria and assessed dietary quality before and during pregnancy using a 30-day qualitative food frequency questionnaire. We compared changes in dietary quality and specific food group mean scores using paired t-tests at p < 0.05. Of the 508 women enrolled, 22.7% were diagnosed with GDM. The overall diet quality significantly decreased during pregnancy compared to before; a similar trend was observed in women diagnosed with GDM compared to those without GDM (p < 0.0001). Among women with GDM, the mean score of the following food groups significantly (p < 0.05) decreased during pregnancy: cruciferous vegetables, deep orange vegetables and tubers, citrus fruits, deep orange fruits, other fruits, nuts and seeds, poultry, fish, low fat dairy, whole grains, and liquid oils and significantly (p < 0.05) increased in the following food groups; red meat, processed meat, sugar-sweetened beverages, sweets, sugary snacks and ice cream. In conclusion, GDM is prevalent in Malawian women enrolled in this study and is coupled with inadequate dietary quality, especially during pregnancy. Since dietary quality is pivotal to GDM management, more in-depth longitudinal dietary studies are needed to inform nutritional interventions to prevent and better manage GDM.
The inner ear is a complex sensory organ with finely balanced physiology; disrupting this may cause hearing changes or vestibular symptoms. Pregnancy involves multiple significant reversible alterations in physiological state. This study reviews literature on the inner ear in pregnancy.
Methods
The review was pre-registered on the PROSPERO database CRD42023446898. Robust searches were conducted by two independent researchers according to the PRISMA 2020 guideline.
Results
A total of 69 studies were filtered into the final analysis. Consistent evidence of subclinical hearing loss in pregnancy was identified, which resolved following childbirth. Auditory processing is affected by pregnancy. Vestibular dysfunction may contribute to pregnancy nausea. Sudden sensorineural hearing loss does not occur more frequently in pregnancy.
Conclusion
This review summarises evidence for reversible and irreversible changes to hearing and vestibular function in pregnancy and pregnancy-related conditions, reviewing aetiological theories and offering insight to audiovestibular physiology and explaining audiovestibular symptoms in the pregnant patient.
Cardiac disease complicating pregnancy is present in a relatively small number of women; however, it accounts for a disproportionate share of maternal morbidity and mortality, especially in developing/emerging countries. The prevalence of cardiac disease in pregnancy is increasing and there are multiple underlying etiologies with wide-ranging severity. Normal adaptions during pregnancy often further challenge already compromised anatomic and physiologic compensatory mechanisms of the cardiovascular system, increasing the risk of adverse maternal and fetal outcomes. In this Element, the authors describe how these changes alter nonpregnant physiology with a variety of preexisting and newly diagnosed cardiac conditions. Maternal and fetal risks are reviewed. Diagnosis and management, from before conception through the postpartum period including appropriate contraception, is discussed. The goal of this review is to increase understanding of the importance of cardiac disease in pregnancy and encourage high-quality multidisciplinary care, and thus improve maternal and fetal outcomes.
Howard CH Khoe, National Psychiatry Residency Programme, Singapore,Cheryl WL Chang, National University Hospital, Singapore,Cyrus SH Ho, National University Hospital, Singapore
Chapter 36 covers the topic of catatonia and electroconvulsive therapy . Through a case vignette with topical MCQs for consolidation of learning, readers are brought through the management of a patient with catatonia from first presentation to subsequent complications of the conditions and its treatment with electroconvulsive therapy (ECT) and other medications. Things covered include the symptoms, diagnosis, differential diagnoses, investigations, the evidence-based use and indications of pharmacological treatment such as benzodiazpines and ECT, adverse effects of ECT, management of adverse cognitive effects from ECT and use of ECT in pregnancy.
Howard CH Khoe, National Psychiatry Residency Programme, Singapore,Cheryl WL Chang, National University Hospital, Singapore,Cyrus SH Ho, National University Hospital, Singapore
Chapter 52 covers the topic of pregnancy and breastfeeding. Through a case vignette with topical MCQs for consolidation of learning, readers are brought through the management of pregnant patients with psychiatric disorders from first presentation to subsequent complications of the conditions and its treatment. Things covered include the general principles of prescribing in patients with pregnancy or who are breastfeeding, the use of antidepressants, the use of mood stabilisers, the use of antipsychotics.
Physiologic changes in the peripartum period put women with CHD at increased risk for morbidity. This study examines factors associated with peripartum complications and length of stay compared to patients without CHD.
Methods:
This single-institution retrospective case-control study included women with CHD (2000–2017) and a control population without CHD. A review of clinical and echocardiographic data was used to assign baseline characteristics, disease severity, and adverse outcomes. Primary outcomes were composite variables of cardiac and obstetric adverse events, along with peripartum length of stay. The relationship between maternal CHD, baseline characteristics, and peripartum adverse events was evaluated by multivariable regression.
Results:
The cohort and control groups included 162 deliveries among 113 women and 321 deliveries among 321 women, respectively. Cardiac complications, including arrhythmia, heart failure, pulmonary oedema, and thromboembolic events, occurred in 8.6% of the cohort (RR 2.52, 95% CI 1.17–5.42), with the most common event being arrhythmia. Obstetric events, such as caesarean delivery, assisted vaginal delivery, preterm birth, and pre-eclampsia, occurred in 67.9% versus 56.1% in the control group (RR 1.21, 95% CI 1.05–1.40). In multivariable models, increasing age was associated with increased composite cardiac events. Length of stay was longer in the cohort group (p < 0.001) and significantly associated with modified World Health Organization classification (p = 0.016).
Conclusions:
Women with CHD experience increased cardiac and obstetric morbidity compared to controls during peripartum admission. Those with CHD have longer hospital stays around delivery, which is associated with disease severity.
Endothelial progenitor cells (EPCs) are key regulators of vascular homeostasis in both health and disease, playing a crucial role in regenerating the human vascular lining throughout life. These circulating cells can differentiate into mature endothelial cells and are increasingly recognized as important biological markers of vascular function and cumulative risk for various diseases, including cardiovascular conditions. In recent decades, the role of EPCs, particularly the endothelial colony-forming cells (ECFCs) subtype, in pregnancy-related disorders and maternal and neonatal endothelial health has garnered significant attention. Evidence suggests that ECFCs may serve as predictor of future endothelial health in women and their offspring following pregnancy complications, making them particular relevant for research and therapeutic applications in adulthood, as well as potential indicators of vascular health. This review summarizes the evidence on EPCs, specifically ECFCs, as biomarkers of endothelial health in pregnancy, pregnancy-related diseases and ageing, with a focus on maternal and foetal endothelial abnormalities that may serve as prognostic factors for the development of future diseases.
Certain prescription drugs used during pregnancy are associated with offspring autism spectrum disorder (ASD). Nonetheless, ASD risk following prenatal exposure to most drugs remains unknown. Furthermore, methodological challenges and ethical concerns hinder the scope for causal inference.
Methods
We used a case-cohort study design of a nationally representative sample from Israel to examine the associations between maternal prescription drug use during pregnancy and offspring ASD. To scrutinize these associations, the analyses were (a) adjusted for indication proxy (level 2 Anatomical Therapeutic Chemical (ATC) codes), (b) repeated using shared pharmacological targets as exposures, and (c) inspected further through target-enrichment analysis.
Results
The sample included 1,400 individuals with and 94,713 without an ASD diagnosis. Among all drugs prescribed during pregnancy, five were statistically significantly associated with increased offspring ASD risk after adjustment for indication proxy (e.g., hazard ratio [95% confidence interval] cyproterone = 2.71 [1.17–6.25] and prednisolone = 2.10 [1.27–3.49]), and two with decreased risk (ferrous sulfate = 0.82 [0.68, 0.99] and lynestrenol = 0.43 [0.2, 0.93]). Further analysis revealed four pharmacological targets shared by these drugs, which were themselves associated with ASD (e.g., neuronal acetylcholine receptor α4β4 = 1.45 [1.05–1.99] and serotonin 2b receptor = 1.31 [1.04–1.61]). Enrichment analysis suggested the association between ASD and medications affecting cholinergic and serotonergic signaling.
Conclusions
Increased ASD risk followed prenatal exposure to five prescription drugs, and decreased risk followed exposure to two. Subsequent analyses suggested no confounding by indication in these associations, but further studies are warranted.
Fear of childbirth (FoB) is a common experience during pregnancy which can cause clinically significant distress and impairment. To date, a number of investigations of FoB have assumed that clinically significant FoB is best understood as a type of specific phobia. However, preliminary evidence suggests that specific phobia may not be the only diagnostic category under which clinically significant symptoms of FoB are best described.
Aim:
The current study is the first to investigate which DSM-5 diagnostic categories best describe clinically significant symptoms of FoB.
Method:
Pregnant people reporting high levels of FoB (n=18) were administered diagnostic interviews related to their experience of FoB.
Results:
Participants (n=18) were predominantly nulliparous (73.3%), cisgender women (83.3%). Of these, 14 (77.8%) met criteria for one or more DSM-5 anxiety-related disorders. Preliminary findings suggest that primary FoB may align with specific phobia criteria, whereas secondary FoB (following a traumatic birth) may be better classified under post-traumatic stress disorder (PTSD). FoB also featured in other anxiety-related disorders but was not the primary focus (e.g. obsessive-compulsive disorder). Four participants did not meet criteria for any DSM-5 disorder.
Conclusions:
Findings provide preliminary evidence that clinically significant FoB fits within existing DSM-5 categories, in particular specific phobia and PTSD. Although FoB-related concerns appears in other anxiety-related disorder categories, it does not appear as the primary focus. Although informative, due to the small sample employed in this research, replication in larger and more diverse samples is needed.
To describe the nutritional intake and status of pregnant women in Bloemfontein and compare across different household food security categories.
Design:
Cross-sectional.
Setting:
Pelonomi Tertiary Hospital.
Participants:
427 pregnant women were interviewed using a standard questionnaire and a quantitative FFQ to collect socio-demographic, HIV status, household food security, supplement and dietary intake data. Weight and height were measured using standard anthropometric techniques and capillary blood taken by finger-prick for anaemia, Fe and inflammation status assessment.
Results:
26·7 % of participants were food secure, while 11·5 %, 32·1 % and 29·5 % experienced mild, moderate and severe food insecurity, respectively. 54·5 %, 41·7 % and 31·1 % were obese, anaemic and Fe deficient. Median energy intake was 8808 (6978–9223) KJ/d, with no significant differences between the food security groups (P = 0·517). Based on the dietary reference intakes, 98·1 % met the estimated average requirement (EAR) for carbohydrates, but the majority had sub-optimal intake of protein (58·3 %), fibre (60·9 %), pantothenic acid (67·0 %), vitamins C (65·6 %), D (68·4 %), E (59·0 %) and K (61·8 %), potassium (99·8 %), dietary Ca (95·8 %) and Fe (80·8 %). Compared with the moderately and severely food-insecure counterparts, food-secure participants had a higher intake of animal protein (P < 0·001), total fat (P = 0·014), monounsaturated fat (P = 0·002), vitamins B12 (P = 0·014), C (P < 0·001) and D (P = 0·003) and dietary Ca (P = 0·001). Dietary folate intake was below the EAR in 69·9 %, but was higher among severely food-insecure participants (463·94 (327·39, 609·71) µg than food secure (378·49 (265·99, 496·15) µg, P = 0·007)).
Conclusion:
The findings show widespread inadequate nutrient intake among pregnant women in Bloemfontein, with food-insecure women showing significantly lower intake of specific nutrients.
Recently, the role of abortion access in the workplace and the field of I-O psychology has been highlighted, but little published research explicitly tackles the impacts of abortion care from an organizational psychology perspective. We examine the potential impacts of further restrictions on abortion access within the context of people’s relationships with employment and workplaces. We focus our discussion on three significant mechanisms that may further restrict access to abortion depending on the degree to which they are enforced or enacted: restriction of abortion medication and equipment shipping, limiting federal funding for organizations that facilitate abortion access, and fetal personhood laws. Further restriction of abortion access may create significant challenges for organizational decision makers, employees, and healthcare workers. Together, these changes to the experience of work necessitate shifts in research and practice within the field of I-O psychology. I-O researchers and practitioners must work together to facilitate organizational functioning and employee well-being through these changes by becoming and staying informed about organizational benefit policies and reproductive care-related practices and their impact on employees, employee career trajectories and distress related to unwanted pregnancy, and moral injury and other challenges faced by healthcare workers.