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A thorough and detailed understanding of normal development in childhood provides a basis upon which we can build knowledge of children’s mental health difficulties. Development refers to expected patterns of change over time, beginning at conception and continuing throughout the lifespan. It is a lifelong process and encompasses different domains, including the physical, social, emotional, and cognitive.
Is the way my child plays with others suggestive of Autism? Could his bad dreams indicate anxiety? Does the fact she can’t sit through a whole film mean she has ADHD? Only with an in-depth knowledge of what is developmentally ‘normal’, can we begin to elicit whether behaviours that deviate from these norms might indicate disorder. This is the basis of the developmental psychopathology that underpins the practice of Child & Adolescent Psychiatry. What is considered ‘normal’ development involves a complex and continuous interplay between genetic and environmental (including sociocultural) factors. Despite some variation, there is a consistency and reliability of functioning in children that remains steadfast from generation to generation.
In this chapter we will consider areas including the milestones of development in early childhood; attachment theory, temperament and personality; theories of emotional, cognitive and social development; and development in adolescence.
Subtle behavioral and cognitive symptoms precede schizophrenia (SCZ) and appear in individuals with elevated risk based on polygenic risk scores (SCZ-PRS) and family history of psychosis (SCZ-FH). However, most SCZ-PRS studies focus on European ancestry youth, limiting generalizability. Furthermore, it remains unclear whether SCZ-FH reflects common-variant polygenic risk or broader SCZ liability.
Methods
Using baseline data from the Adolescent Brain Cognitive Development (ABCD) study, we investigated associations of SCZ-FH and SCZ-PRS with cognitive, behavioral, and emotional measures from NIH-Toolbox, Child Behavior Checklist (CBCL), and Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS) for 9,636 children (mean age = 9.92 yrs, 47.4% female), specifically, 5,636 European, 2,093 African, and 1,477 Admixed American ancestry individuals.
Results
SCZ-FH was associated with SCZ-PRS (b = 0.05, FDR-p = 0.02) and subthreshold psychotic symptoms (b = 0.46, FDR-p = 0.01) in European youth, higher CBCL scores (b range = 0.36–0.6, FDR-p < 0.001), and higher odds of multiple internalizing and externalizing disorders (OR = 1.10–1.22, FDR-p < 0.001) across ancestries. SCZ-PRS was associated with lower cognition across ancestries (b = −0.43, FDR-p = 0.02), higher CBCL total problems, anxious/depressed, rule-breaking and aggressive behaviors in European youth (b range = 0.16–0.33, FDR-p < 0.04), and depressive disorders in Admixed American youth (OR = 1.37, FDR-p = 0.02). Results remained consistent when SCZ-PRS and SCZ-FH were jointly modeled. Some SCZ-FH associations weakened when income-to-needs was accounted for, suggesting that SCZ-FH may capture both genetic and environmental influences.
Conclusions
SCZ-FH showed associations with broad psychopathology, while SCZ-PRS was associated with cognition and specific symptoms in European youth. Findings highlight their complementary role in SCZ risk assessment and the need to improve PRS utility across ancestries.
This Element describes the development of a Theory of Mind, or mentalizing, in infancy and early childhood. Theory of Mind is a key social cognitive ability that permits children to predict and explain human behaviors by attributing mental states to other people. Understanding mental states gradually progresses from basic desires to false beliefs. The Element reviews the proximal and distal cognitive and social determinants that facilitate early Theory of Mind development. Discoveries in neuroscience contribute to understanding the ontogeny of Theory of Mind. This Element presents an overview of the main theoretical accounts of Theory of Mind development and offers suggestions for future research.
Impulsivity is among the strongest correlates of substance involvement (i.e. a broad continuum of substance-related behaviors), and distinct domains (e.g. sensation seeking [SS] and urgency) are differentially correlated, phenotypically and genetically, with unique substance involvement stages. Examining whether polygenic influences for distinct impulsivity domains are differentially predictive of early substance use initiation – a major risk factor for later problematic use – may improve our understanding of the role of impulsivity in addiction etiology.
Methods
Data collected from participants of genetically inferred European ancestry enrolled in the Adolescent Brain Cognitive Development StudySM (n = 4,808) were used to estimate associations between polygenic scores (PGSs) for UPPS-P impulsivity domains (i.e. SS, lack of premeditation [LPREMED]/perseverance [LPERSEV], and negative/positive urgency [NU/PU]) and substance (i.e. any, alcohol, nicotine, and cannabis) use initiation by age 15 years. Mediation models examined whether child impulsivity (ages 9–11 years) mediated links between PGSs and substance use initiation.
Results
SS-PGS was significantly associated with any substance and alcohol use initiation (odds ratio [ORs] > 1.10, psFDR < 0.05). LPERSEV and NU/PU PGSs were nominally associated with alcohol and nicotine use initiation, respectively (ORs > 1.06, ps < 0.05, psFDR > 0.05). No significant associations were observed for LPREMED-PGS or cannabis use initiation. Measured impulsivity domains accounted for 5–9% of associations between UPPS-P PGSs and substance use initiation.
Conclusions
Genetic influences for distinct impulsivity domains have differential associations with early substance use initiation, with SS showing the most robust associations, highlighting valuable etiological insight into the earliest stages of substance involvement that may be leveraged to improve prevention and intervention strategies.
This chapter argues that researchers in child development and children’s well-being should take culture seriously by showing how social and cultural settings in which children grow up matter for understanding the varieties of childhoods documented ethnographically. It begins with a historical review of anthropological research on childhood and children’s worlds. Much of the early work on children’s development in culture focused on how children become competent members of their societies. This tended to present children’s development in locally normative terms and social and cultural development as static. Later research focused on the problem of accelerating global social change and documented the struggles children, their families, and communities confronted in the face of social change. It also examined the positive role children played, particularly as sources of innovation in adaptive strategies. Children were seen less as sites of internalization and more as agents of active participation. The chapter concludes with a discussion of the strengths that psychological anthropologists bring to childhood studies and possible future directions for new research.
Howard CH Khoe, National Psychiatry Residency Programme, Singapore,Cheryl WL Chang, National University Hospital, Singapore,Cyrus SH Ho, National University Hospital, Singapore
Chapter 50 covers the topic of child and adolescent mental health services. Through a case vignette with topical MCQs for consolidation of learning, readers are brought through the management of young patients with psychiatric disorders from first presentation to subsequent complications of the conditions and its treatment. Things covered include the general principles of prescribing in children and adolescent patients with psychiatric disorders, the use of antidepressants, the use of mood stabilisers, the use of antipsychotics, treatment of anxiety disorders.
Patients diagnosed with hypertension (HT) are at high risk for end-organ damage. With changing living conditions and access to healthcare facilities worldwide, the rate of diagnosis in childhood is increasing. In this study, healthy children were compared with a group of pediatric patients diagnosed with hypertension. Cardiac findings in the hypertensive group were compared at presentation and at six months. We aimed to determine the discriminatory value of epicardial adipose tissue (EAT) measurements as an early imaging marker for cardiac involvement in children with HT compared to healthy children and to determine its prognostic feature for HT treatment response.
Methods:
Fifty-nine primary hypertension patients and 76 control patients aged 0-18 years were compared. EAT values measured between the healthy group and the patient group and at the beginning of treatment and subsequent follow-ups in the patient group were evaluated with M-mode measurements.
Results:
There was no difference between the groups in terms of sex, and age. EAT was found to be significantly higher in the patient group than in the healthy group. There was a statistically significant difference between the EAT measurements evaluated before and after treatment in the patient group.
Conclusions:
Hypertension is an important cause of morbidity and mortality. Using EAT measurements as a noninvasive parameter may provide information about early cardiac involvement due to HT. EAT is promising as an imaging marker that can be used in diagnosis and follow-up.
The study of infant, child, and adolescent remains (non-adult remains) is a topic of growing interest within the fields of archaeology and bioarchaeology. Many published volumes and articles delve into the experiences of childhood and what these small remains may tell us about life, more broadly, in the past. For those interested in exploring infant and child remains, it is an exciting period as more methods and approaches are constantly being incorporated into the archaeological toolkit. This Element introduces the reader to the topic and to common methodological approaches used to consider non-adult remains from archaeological contexts. With this toolkit in hand, readers will be able to begin their own explorations and analyses of non-adult human remains within archaeological contexts.
Epilepsy syndromes (electroclinical syndromes) are well-recognized groupings of clinical (seizure types) and EEG features that occur together. Each syndrome typically shares a common age of onset, deficits (intellectual dysfunction), treatment and prognosis. Syndromes are classified based on their onset, epilepsy type (focal, generalized, or mixed) and development of epileptic encephalopathy (disorder in which epileptic activity contributes to severe impairments in cognition and behavior). Relatively benign syndromes are typically associated with focal, generalized tonic-clonic (GTC), typical absences and myoclonic seizures. Epileptic encephalopathies are typically associated with atonic, tonic, atypical absences, and epileptic spasms in addition to the other seizure types. [106 words/729 characters]
This chapter describes the spectrum of age-related maturation of electrographic patterns through preterm, neonatal, infantile, childhood, and adolescence periods. Neonatal EEGs must be interpreted in the context of corrected age and physiological state. Sustained continuity is the hallmark of maturation. Preterm records are discontinuous irrespective of state while term records are continuous in all states. Between 30 and 37 weeks, the background becomes more continuous during wakefulness and active sleep compared to quiet sleep. At term, activité moyenne is present during wakefulness and active sleep and trace alternans occurs during quiet sleep. Anterior dysrhythmia and graphoelements occur between 32 and 44 weeks corrected age. Sharp transients may be normal in neonates. A reactive posterior dominant rhythm emerges at three months of age and attains alpha range at around 2 to 3 years of age. Asynchronous sleep spindles emerge before 3 months and synchronize at 6 months of age. [144 words/855 characters]
This chapter provides a preliminary Latinx literary history of both the representation of Latinxs in video games and how games shape narratives of Latinidad in the twenty-first century. The chapter first examines how non-Latinxs have dominated Latinx narratives and representation, shaping a narrow concept of who is Latinx and what it means to live as a Latinx person. While AAA games continue to circulate stereotyped images of Latinxs, more recent game narratives authored by Latin American and Latinx creators and distributed through independent publishers challenge these representations. The chapter provides close readings of Guacamelee! and Guacamelee! 2 from Drinkbox Studies and Minority Media’s Papo & Yo, both created by Latin American immigrants to North America. These games subvert gaming tropes and use characterization and worldbuilding to showcase the diversity of Latinidades. Finally, the chapter assesses video games that expand representation (including AfroLatinidades and trans Latinidades) as well as narratives that use ludic structures, such as Carmen Maria Machado’s In the Dream House: A Memoir and Nona Fernández’s Space Invaders.
Across Australia and beyond, early childhood education (ECE) services play a significant role in the everyday lives of infants, toddlers and their families. For some decades, the enrolment of infants and toddlers has increased to the extent that, in today’s Australian society, around 40% of birth to 24-month-olds and nearly 60% of two-year-olds spend at least part of their week in an early childhood service. More still balance ECE service attendance with informal care arrangements with family members and friends. With these figures echoed across many countries worldwide, the widespread uptake of infant and toddler early childhood programs has meant that this generation of infants and toddlers and their families are experiencing a markedly different start to life than previous generations. It is now the norm for infant–toddler care to be spread across multiple contexts both within and outside of the walls of the family home, and for the responsibility for early learning to be shared between family and non-familial adults.
Examines some philosophical issues raised by the problem of dressing children. These include Enlightenment discussions of childhood, education, and clothing, which arguably had a large impact on the development of children’s fashion. Discusses the extent to which parents and caretakers shape children’s identity through their choice of clothing.
Clothes are much more than just what we put on in the morning. They express our identity; they can be an independent statement or the result of coercion; and they have deeply entrenched historical, political, and social aspects. Kate Moran explores the connections between clothes and philosophy, showing how clothes can illustrate and pose philosophical problems, and how philosophical ideas influence clothing. She discusses what it might mean for an article of clothing to be beautiful; how we communicate with clothes; how we use clothes to navigate our social existence; and how our social existence leaves its mark on our clothes. She also considers the curious relationship between philosophers and children's clothes, legal restrictions on clothing, textile waste, and labor conditions of textile workers. Her absorbing and engaging portrait of our clothes helps us to understand an important and underexplored aspect of our lives.
There are 117.3 million people forcibly displaced because of war, conflict and natural disasters: 40% are children. With growing numbers, many high-income countries have adopted or are considering increasingly restrictive policies of immigration detention. Research on the impact of detention on mental health has focused on adults, although recent studies report on children.
Aims
To synthesise data on the impact of immigration detention on children’s mental health.
Method
Systematic searches were conducted in PsycINFO, MEDLINE and Embase databases and grey literature and studies assessed using PRISMA guidelines (PROSPERO registration CRD42023369680). Included studies were quantitative, assessed children younger than 18 years who had been in immigration detention and reported mental health symptoms or diagnoses. Methodological quality was assessed using the Appraisal Tool for Cross-Sectional Studies. Meta-analyses estimated prevalence for major depression and post-traumatic stress disorder (PTSD).
Results
Twenty-one studies reported data on 9620 children. Most studies were cross-sectional, had small sample sizes and used convenience sampling. A profoundly detrimental impact on children’s mental health across a variety of countries and detention settings was demonstrated. Meta-analysis found pooled prevalence of 42.2% for depression [95% CI 22.9, 64.3] and 32.0% for PTSD [95% CI 19.4, 48.0]. Severity of mental health impact increased with exposure to indefinite or protracted held detention.
Conclusions
Immigration detention harms children. No period of detention can be deemed safe, as all immigration detention is associated with adverse impacts on mental health. Our review highlights the urgency of alternative immigration policies that end the practice of detaining children and families.
The health and well-being of families is an important consideration for federal, state, and/or local levels of government. Family health policies based on recent knowledge of early childhood development have evolved to emphasise the importance of providing every child with the best possible start to life. Childhood sets the foundation for future health and well-being and is recognised by the 1979 United Nations Convention on the Rights of the Child. To impact health inequalities, government policies and services must address the social determinants of early child health, development and well-being.
Desminopathy is a rare heritable cardiac and skeletal muscle disease caused by variants in the DES gene, which encodes the primary muscle-specific intermediate filament protein, known as desmin. Childhood-onset is commonly associated with severe early-onset myopathy and early death. Here, we reported an 11-year-old Chinese girl presenting with complete atrioventricular block and cardiomyopathy, without skeletal muscle involvement. Genetic analysis identified a de novo variant (c.152C > T/p.Ser51Phe) in the DES gene.
This study aimed to investigate the association between family characteristics and adherence to the EAT-Lancet dietary recommendations in 7-year-old children. This is a prospective birth cohort study with 2125 children from Generation XXI (Porto, Portugal), who provided 3-day food diaries at age 7, used to assess habitual food consumption. At the age of 4, maternal diet was assessed using a Food Frequency Questionnaire, and a diet quality score was calculated (higher scores indicating a better maternal diet), and parental–child feeding practices were assessed with the Child Feeding Questionnaire. Adherence to the EAT-Lancet dietary recommendations was evaluated using the World Index for Sustainability and Health (WISH) at the age of 7 years, previously adapted to paediatric age. Hierarchical linear regression models (consecutive addition of blocks of variables based on a theoretical framework) were employed to evaluate the associations between family characteristics and adherence to the WISH at age 7 (β regression coefficients and the respective 95 % confidence intervals (95 % CI)). Higher maternal age and education at child’s birth were associated with increased adherence to the WISH at age 7 (β = 0·018, 95 % CI 0·005, 0·031; β = 0·038, 95 % CI 0·024, 0·053, respectively). A better maternal diet quality and using more restrictive practices on child’s diet, at 4 years old, were both associated with higher scoring in the WISH at 7 years old (β = 0·033, 95 % CI 0·018, 0·049; β = 0·067, 95 % CI 0·009, 0·125, respectively). Early maternal sociodemographic and diet quality play a significant role in influencing the adherence to a healthy and environmentally sustainable dietary pattern at school-age.
A 7-year-old girl visited the outpatient clinic because of difficulty walking. She had never managed to run properly, and experienced frequent falls ever since she began walking independently at the age of 18 months. Jumping was not possible, and when stepping up or down, she needed support below her arms. There was no fluctuation of symptoms during the day, but she had suffered from periods that could last several weeks in which using the stairs was completely impossible. She was unable to blow up a balloon and her speech was slow and poorly articulated. There were no complaints about chewing or swallowing. She had a healthy non-identical twin sister and the family history was unremarkable.
Private speech is a tool through which children self-regulate. The regulatory content of children’s overt private speech is associated with response to task difficulty and task performance. Parenting is proposed to play a role in the development of private speech as co-regulatory interactions become represented by the child as private speech to regulate thinking and behaviour. This study investigated the relationship between maternal parenting style and the spontaneous regulatory content of private speech in 3- to 5-year-old children (N = 70) during a problem-solving Duplo construction task. Sixty-six children used intelligible private speech which was coded according to its functional self-regulatory content (i.e., forethought, performance, and self-reflective). Mothers completed the Australian version of the Parenting Styles and Dimensions Questionnaire. Results revealed a significant positive association between maternal authoritative parenting and the frequency and proportion of children’s forethought type (i.e., planning and self-motivational) utterances during the construction task. There were no significant associations between maternal parenting style and other private speech content subtypes.