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Immunological manipulation of adiposity

Published online by Cambridge University Press:  28 February 2007

David J. Flint
David J. Flint
Affiliation:
Hannah Research Institute, Ayr KA6 5HL
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Abstract

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Information

Type
Symposium on ‘The manipulation of adiposity’
Information
Proceedings of the Nutrition Society , Volume 51 , Issue 3 , December 1992 , pp. 433 - 439
Copyright
Copyright © The Nutrition Society 1992

References

REFERENCES

Aston, R., Holder, A. T., Preece, M. A. & Ivanyi, J. (1986). Potentiation of the somatogenic and lactogenicactivity of human growth hormone with monoclonal antibodies. Journal of Endocrinology 110, 381–388.CrossRefGoogle ScholarPubMed
Bass, S. H., Mulkerrin, M. G. & Wells, J. A. (1991). A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor. Proceedings of the National Academy of Science, USA 88, 4498–4502.CrossRefGoogle ScholarPubMed
Beck, B. (1989). Gastric inhibitory polypeptide: a gut hormone with anabolic functions. Journal of Molecular Endocrinology 2, 169–174.CrossRefGoogle ScholarPubMed
Bergen, W. G., Johnson, S. E., Skjaerlund, D. M., Merkel, R. A. & Anderso, D. B. (1987). The effect of ractopamine on skeletal muscle metabolism in pigs. Federation Proceedings 46, 1021.Google Scholar
Bomford, R. & Aston, R. (1990). Enhancement of bovine growth hormone activity by antibodies against growth hormone peptides. Journal of Endocrinology 125, 31–38.CrossRefGoogle ScholarPubMed
Cunningham, B. C., Ultsch, M., de Vos, A. M., Mulkerrin, M. G., Clauser, K. R. & Wells, J. M. (1991). Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science 254, 821–825.CrossRefGoogle ScholarPubMed
de Vos, A. M., Ultsch, M. & Kossiakoff, A. A. (1992). Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255, 306–312.CrossRefGoogle ScholarPubMed
Dulor, J. P., Reyne, Y. & Nougues, J. (1990). In vivo effects of a treatment with antibodies to adipocyte plasma membranes in the rabbit. Reproduction Nutrition Developpement 30, 49–58.CrossRefGoogle ScholarPubMed
Eadara, J., Dalrymple, R. H., De Lay, R. L., Ricks, C. A. & Romsos, D. R. (1987). Cimaterol, a novel β-agonist, selectively stimulates white adipose tissue lipolysis and skeletal muscle lipoprotein lipase activity in rats. Federation Proceedings 46, 1020.Google Scholar
Ebert, R. & Creutzfeldt, W. (1987). Gastrointestinal peptides and insulin secretion. Diabetes and Metabolism Reviews 3, 1–26.CrossRefGoogle ScholarPubMed
Ebert, R., Illmer, K. & Creutzfeldt, W. (1979). Release of gastric inhibitory polypeptide (GIP) by intraduodenal acidification in rats and humans and abolishment of the incretin effect of acid by GIP-antiserum in rats. Gastroenterology 76, 515–523.CrossRefGoogle ScholarPubMed
Etherton, T. D., Wiggins, J. P., Evock, C. M., Chung, C. S., Rebhun, J. F., Walton, P. E. & Steele, N. C. (1987). Stimulation of pig growth performance by porcine growth hormone: determination of the dose-response relationship. Journal of Animal Science 64, 433–443.CrossRefGoogle ScholarPubMed
Faulkner, A. & Pollock, H. T. (1991). Effects of truncated glucagon-like peptide-1 on the responses of starved sheep to glucose. Journal of Endocrinology 129, 55–58.CrossRefGoogle ScholarPubMed
Flint, D. J., Coggrave, H., Futter, C. E., Gardner, M. J. & Clarke, T. J. (1986). Stimulatory and cytotoxic effects of an antiserum to adipocyte plasma membranes on adipose tissue metabolism in vitro and in vivo. International Journal of Obesity 10, 69–77.Google ScholarPubMed
Gardner, M. J., Morrison, C. A., Stevenson, L. Q. & Flint, D. J. (1990). Production of anti-idiotypic antisera to rat GH antibodies capable of binding to GH receptors and increasing body weight gain in hypophysec- tomized rats. Journal of Endocrinology 125, 53–59.CrossRefGoogle Scholar
Hanrahan, J. P., Quirke, J. F., Bomann, W., Allen, P., McEwan, J. C., Fitzsimmons, J. M., Kotzain, J. & Roche, J. F. (1986). β-Agonists and their effects on growth and carcass quality. In Recent Advances in Animal Nutrition, pp. 125–138 [Haresign, W. and Cole, D. J. A., editors]. London: Butterworths.CrossRefGoogle Scholar
Holder, A. T. & Aston, R. (1989). Antigen-antibody complexes that enhance growth. In Biotechnology and Growth Regulation, pp. 167–177 [Heap, R. B., editor]. London: Butterworths.CrossRefGoogle Scholar
Holder, A. T., Aston, R., Preece, M. A. & Ivanyi, J. (1985). Monoclonal antibody-mediated enhancement of growth hormone activity in vivo. Journal of Endocrinology 107, R9–R12.CrossRefGoogle ScholarPubMed
Jerne, N. K. (1974). Towards a network theory of the immune system. Annals of lmmunology, Paris 125c, 373–389.Google ScholarPubMed
McCarthy, J. P., Faulkner, A., Martin, P. A. & Flint, D. J. (1992). Changes in the plasma concentration of gastric inhibitory polypeptide and other metabolites in response to feeding in sheep. Journal of Endocrinology 134, 235–240.CrossRefGoogle ScholarPubMed
Maltin, C. A., Hay, S. M., Delday, M. I., Smith, F. G., Lobley, G. E. & Reeds, P. J. (1987). Clenbuterol, a beta agonist, induces growth in innervated and denervated rat soleus muscle via apparently different mechanisms. Bioscience Reports 7, 525–532.CrossRefGoogle ScholarPubMed
Moloney, A. P. & Allen, P. (1989). Growth and weights of abdominal and carcass fat in sheep immunized against adipose cell membranes. Proceedings of the Nutrition Society 48, 14A.Google Scholar
Nassar, A. H. & Hu, C. Y. (1991). Growth and carcass characteristics of lambs passively immunized with antibodies developed against ovine adipocyte plasma membranes. Journal of Animal Science 69, 578–586.CrossRefGoogle ScholarPubMed
Panton, D., Futter, C., Kestin, S. & Flint, D. J. (1990). Increased growth and protein deposition in rats treated with antibodies to adipocytes. American Journal of Physiology 258, E985–E989.Google ScholarPubMed
Pell, J. M. & Bates, P. C. (1991). The nutritional regulation of growth hormone action. Nutrition Research Reviews 3, 163–192.CrossRefGoogle Scholar
Pell, J. M., Flint, D. J., James, S. & Aston, R. (1991). Immunomodulation of hormones of the somatotropin axis. In Biotechnology for the Control of Growth and Product Quality in Meat Production, pp. 51–66 [Van der Wal, P., editor]. Wageningen: Pudoc.Google Scholar
Pell, J. M., Johnsson, I. D., Pullar, R. A., Morrell, D. J., Hart, I. C., Holder, A. T. & Aston, R. (1989). Potentiation of growth hormone activity in sheep using monoclonal antibodies. Journal of Endocrinology 120, R15–R18.CrossRefGoogle ScholarPubMed
Spencer, G. S. G., Garssen, G. J. & Hart, I. C. (1983 a). A novel approach to growth promotion using autoimmunization against somatostatin. I. Effects on growth and hormone levels in lambs. Livestock Production Science 10, 25–37.CrossRefGoogle Scholar
Spencer, G. S. G., Garssen, G. J. & Hart, I. C. (1983 b). A novel approach to growth promotion using autoimmunization against somatostatin. II. Effects on appetite, carcass composition and food utilization in lambs. Livestock Production Science 10, 469–477.CrossRefGoogle Scholar
Thomas, H., Green, I. C., Wallis, M. & Aston, R. (1987). Heterogeneity of growth-hormone receptors detected with monoclonal antibodies to human growth hormone. Biochemical Journal 243, 365–372.CrossRefGoogle ScholarPubMed
Trout, W. E. & Schanbacher, B. D. (1990). Growth hormone and insulin-like growth factor-I responses in steers actively immunized against somatostatin or growth hormone-releasing factor. Journal of Endo- crinology 125, 123–129.CrossRefGoogle ScholarPubMed
Vernon, R. G., Finley, E. & Flint, D. J. (1987). Role of growth hormone in the adaptions of lipolysis in rat adipocytes during recovery from lactation. Biochemical Journal 242, 931–934.CrossRefGoogle ScholarPubMed
Vernon, R. G. & Flint, D. J. (1989). Role of growth hormone in the regulation of adipocyte growth and function. In Biotechnology in Growth Regulation, pp. 55–71 [Heap, R. B., Prosser, C. G. and Lamming, G. E., editors]. London: Butterworths.Google Scholar
Wamss, P. D. & Kestin, S. C. (1988). Beta-agonists improve the carcass but may reduce meat quality in sheep. Animal Production 46, 502.Google Scholar
Warriss, P. D., Kestin, S. C. & Brown, S. N. (1989). The effect of beta-adrenergic agonists on carcass and meat quality in sheep. Animal Production 48, 385–392.Google Scholar
Wamss, P. D., Kestin, S. C., Rolph, T. P. & Brown, S. N. (1990). The effects of the beta-adrenergic agonist salbutamol on meat quality in pigs. Journal of Animal Science 68, 128–136.Google Scholar
Yang, Y. T. & McElligott, M. A. (1989). Multiple actions of p-adrenergic agonists on skeletal muscle and adipose tissue. Biochemical Journal 261, 1–10.CrossRefGoogle Scholar