Quality of life (QoL) is a comprehensive concept encompassing an individual’s satisfaction with various aspects of life, including material, social, spiritual needs, intellectual and physical development, and safety. During the COVID-19 pandemic, the quality of life in Russia declined due to environmental and social disruptions. Behavioural self-regulation, which reflects an individual’s ability to manage internal and external conditions, plays a key role in adapting to challenging situations. Thus, exploring the relationship between QoL and self-regulation styles can provide insight into adaptive behaviours under pandemic conditions.

The study aimed to explore the interconnections between quality of life and self-regulation styles in humanities students and people living with HIV during the second wave of COVID-19.

Data were collected from January to July 2021 via a Google form. Participants included 35 Russian university students in humanities and 59 HIV-positive patients. Self-regulation styles were measured using V.I. Morosanova’s “Style of Self-Regulation of Behaviour” questionnaire, and quality of life was assessed with the WHOQOL-BREF, adapted for Russian respondents.

In the group of students positive correlations of physical and psychological well-being with programming (rs = 0.405, p < 0.05); self-perception — with programming (rs = 0.522, p < 0.01), evaluation of results (rs = 0.586, p < 0.01) and general level of self-regulation (rs = 0.389, p < 0.05); microsocial support — with evaluation of results (rs = 0.336, p < 0.05) were found. In the patient group, physical and psychological well-being were associated with outcome evaluation (rs = 0.343, p < 0.01); self-image — with modelling (rs = 0.605, p < 0.01), outcome evaluation (rs = 0.467, p < 0. 01), flexibility (rs = 0.444, p < 0.01) and overall level of self-regulation (rs = 0.439, p < 0.01); microsocial support — with modelling (s = 0.366, p < 0.01); social well-being — with modelling (rs = 0.442, p < 0.01) and flexibility (rs = 0.346, p < 0.01).

The study found that self-perception was the most frequently correlated factor with self-regulatory behaviour in both students and HIV-positive group, indicating that satisfaction with life, sense of purpose, and emotional stability contribute to self-regulation even in challenging conditions. However, social well-being was a unique influencing factor for people living with HIV, highlighting a dependency on material and societal conditions that was less pronounced in student’s group. This suggests that HIV patients are more sensitive to social and environmental stability, whereas students rely more on internal self-regulatory mechanisms for adaptation.

None Declared

Self-regulation refers to a structured mental process for initiating, organizing, maintaining, and managing internal and external activities directed toward achieving goals. Each individual exhibits a unique self-regulation style that influences their capacity to adapt to changing circumstances. During the COVID-19 pandemic, a significant rise in anxiety, depression, and stress levels was noted in Russia. Emotional disorders may relate to self-regulation styles, as they affect an individual’s adaptation to evolving internal and external stressors.

The study investigates relationships between self-regulation styles and depression, anxiety, and stress levels among humanities students and HIV-positive patients, shedding light on how behavioural self-regulation affects emotional responses in different population segments during the pandemic in the Russian Federation.

Data were collected from January to July 2021 using a Google form. The sample included 35 humanities students from Russian universities and 59 HIV-positive patients. V.I. Morosanova’s “Style of Self-Regulation of Behaviour” questionnaire was used to assess self-regulation styles, while the DASS-21, adapted for Russian contexts, measured levels of depression, anxiety, and stress.

We found that in the group of Russian university students, depression had negative correlations with behavioural programming (rs = -0.421, p < 0.05) and with outcome evaluation (rs = -0.401, p < 0.05). In the HIV patient group, depression had negative correlations with modelling (rs = -0.322, p < 0.05) and flexibility (rs = -0.285, p < 0.05), anxiety also with modelling (rs = -0.270, p < 0.05) and flexibility (rs = -0.261, p < 0.05). In both groups, stress was not related to self-regulation behaviour style.

The study highlights the association between emotional disorders and self-regulation was more pronounced in the HIV-positive group. Depression and anxiety corresponded with reduced reality assessment and flexibility in self-regulation. These patients found it more challenging to evaluate internal and external factors and adjust their self-regulatory processes amid changing conditions, indicating a greater vulnerability to disruptions in self-regulation. Within the students’ group, depression alone affected self-regulation, particularly diminishing abilities in programming and outcome evaluation. As depressive symptoms worsened, students struggled to effectively plan actions and assess their behaviour and achievements.

None Declared

ADHD has been seen by current science as an expression of complex traits that go beyond the symptomatological triad of “inattention-hyperactivity-impulsivity”. Among the new notes, experiences of deep concentration (DC) are mentioned as a frequent phenomenon in the daily lives of those with ADHD, which encourages research on this topic.

The main objective of this integrative review was to investigate how empirical scientific studies have evaluated, associated and understood this hyperfocused attentional pattern in individuals with a diagnosis or symptoms suggestive of ADHD.

For searches in the electronic databases PubMed, Scopus, LILACs, Pepsic and Scielo, the terms “attention deficit hyperactivity disorder”, “hyperfocus” and “flow state” were chosen. As inclusion criteria, studies were considered with (a) full texts available, (b) with an empirical design, (c) in English and (d) published in any year. In total, 10 empirical studies were analyzed (8 quantitative and 2 qualitative), Regarding the critical analysis of the included publications, relevant data were extracted about: (a) assessment instruments for deep concentration measures, (b) ADHD assessment instruments, (c) associations between hyperfocus, flow and ADHD and (d) general understandings of researchers on the representation of DC experiences in the lives of those with ADHD.

The sudies indicated a plurality of assessment instruments for both CP constructs (hyperfocus, flow, perseveration) and ADHD symptoms. As main findings, the articles suggest a high prevalence of hyperfocus in adults with ADHD compared to those without the disorder, as well as positive correlations between ADHD symptoms, hyperfocus, perseveration, internet addiction and emotional dysregulation. Different perspectives on the manifestation of DC in ADHD were captured from the studies, whose interpretations ranged from harmful behavior to the potentiality of ADHD.

It was observed that, despite the recent expansion of research trying to understand the phenomenon of hyperfocus in the context of ADHD, scientific knowledge on the topic is still quite limited. In addition to having the unprecedented character of bringing together what modern science has postulated about CP in relation to ADHD, this research is relevant because it contributes to expanding the visibility of ADHD beyond the diagnostic criteria established by the DSM-V-TR and ICD-11.

None Declared

The proposed research work aims to carry out a review of the data of the Assertive Community Treatment Program of Segovia, analyzing its importance in certain profiles of psychiatric patients.

Review of data from the Segovia Assertive Community Treatment Program from 2020-2024: age, sex, nationality, marital status, level of education, diagnosis, family history, substance use, population, socio-family situation, economic situation, follow-up and admissions in Mental health, social health coordination and disability.

Data from the Segovia Assertive Community Treatment Program from 2020-2024.

The majority of patients participating in the Segovia Assertive Community Treatment Program between 2020-2024 were Spanish men between 20 and 60 years old. All patients were single, except three separated and one married. Approximately half of them lived alone and the other half with their family of origin. Most had basic education and half were employed. Regarding the consumption of toxic substances, most of them smoked tobacco and some also consumed alcohol or cannabis, and a small number cocaine. Many of them received a financial benefit and had social-health coordination.

The most common diagnosis is schizophrenia, followed by schizoaffective disorder and delusional disorder, most with psychiatric family history. Other diagnoses that the patients presented were: bipolar disorder, personality disorder and obsessive-compulsive disorder. Some of them also had disabilities.

It is important to highlight that 94.12% of patients live in rural areas, many of them more than 30 minutes away by car and with faced great difficulties with public transportation. Many of them were more previous admissions to Psychiatry and an irregular follow-up in Mental Health, but very few had readmissions during the Program. The majority of patients had psychopharmacological treatment, and 7.14% of them had injectable antipsychotic treatment.

A large percentage of patients in the Assertive Community Mental Health Treatment Program are people who live in a rural environment, with a long distance from the nearest mental health center and with difficulties using public transportation, which is why this program is very useful. In these patients to achieve clinical stability, since these patients had irregular follow-up in Mental Health consultations and had numerous admissions to Psychiatry.

None Declared

Aggression in the psychiatric environment has negative consequences for both patients and staff. Accurate measurement of patient aggression towards staff, and its prevention, remains elusive. The Staff Observation of Aggression Scale-Revised (SOAS-R) is a measure describing the incidence and characteristics of aggressive events. Although not exclusive to staff aggression, our study used this scale to provide a more or less standardized measure for assessing and understanding the trends and potential triggers of staff aggression. This will enable better management of such situations. This in turn will lead to better working conditions and improved quality of care.

To describe the incidence of aggressive events against various mental health staff at Ar-Razi Hospital over the course of a year, their characteristics and the factors involved. this study will provide and enable better managment of these situations, furthermore leading to better work conditions and better quality of care.

• - Our study is a cross-sectional study, data collection were by a questionnaire sent online to hospital staff, the questionnaire was bases on the SOAS-R items.

• - Descriptive and analytical statistical study wad done by Jamovi 2.3 software.

• - Statistical differences were calculated using the chi-2 test, and a p<0.005 value was considered statistically significant.

Our study results(SOAS-R items) concerning the agressions towards staff of our hospital were resumed in image 1 and 2.

Also the prevalence of participating staff by status in our study was: 78% of physical assaults were against nurses. The association between the prevalence of assaults and staff status was statistically significant using the chi-2 test (p=0.0037<0.001).

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Agression is known to have negative impacts for both staff and patients. Our study suggests that mental health staff in our facility are victims of aggression. Improved methods of measuring aggression and a wider study of different psychiatric institutions will help to prevent aggression and create a healthy work environment, which in turn will help the staff to develop and improve the quality of care for patients.

None Declared

Lithium enjoyed its first golden age between 1965 and 1990, but interest in the molecule has not waned, on the contrary, the last 20 years have seen a veritable renaissance in lithium publications. This literature is fuelled by the ongoing exploration of lithium’s unique mood-stabilizing, anti-suicidal and neuroprotective properties, a panoply of properties never before observed in a single molecule. In spite of this, the literature describes little use of lithium, despite ample evidence of its benefits.Our study points the perceptions and misperceptions of lithium and their effects on it use in our hospital.

To study and identify the perceptions and misperceptions of doctors at Ar-razi Hospital about lithium, and thus discuss both of efficacy and safety misperceptions through a litterature review. This study will have as a first objective to correct these mispercetions in order to promote a proper care of our patients.

This is a descriptive study. Data collection was carried out on 50 psychiatrists and trainees. By using an online and handout forms focusing on physicians perceptions and misperceptions of the efficacy and safety of lithium at Ar-razi Hospital in Salé. Jamovi 2.3 was used for data entry and statistical analysis.

our study results were resumed in 2 images. Image 1 is a table that shows the status of our professionnals and also their use of lithum as first or second molecule.

image 2 resumes efficacy perceptions of lithium among our psychiatrists and trainees.

although many other results will be shown by text:

• - 58% thinks that Lithium should not be used in women of childbearing age due to teratogenic risk

• - 73% have the perception that Lithium should be avoided in elderly patients suffering from a lack of efficacy data and safety concerns.

• - 53% thinks that other thymoregulators are safer and should be systematically used in women of childbearing age with bipolar disorder instead of lithium.

• - 84% acclaim that lithium treatment is stopped because of it security profile, when 44% of them thinks that hypothyroidism is prevalent as a secondary effect and causes treatment stop.

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Our study finds that our hospital professionnals have many misperceptions about lithium, especially about it security, which may affect the treatment plan for many patients. This study and it discussion throught the litterature review will change these perceptions, furthermore give the patients a proper care.

Disclosure of new knowledge is essential to refute misconceptions about lithium and enable patients to access its unique therapeutic constellation.

None Declared

Sports psychiatry is a developing subdiscipline, which emphasises the need for adequate treatment and prevention schemes to uphold the mental wellbeing of athletes. Previous studies indicate that elite-level male cyclists face distinctive socioenvironmental risk factors, including external pressures from teams, particularly in relation to weight management concerns. However, there has been little attention to the mental health support available within teams and the awareness of relevant stakeholders to psychiatric issues.

This study sought to gain perspectives on the level of mental health awareness from stakeholders in elite-level cycling teams (i.e., sporting directors, coaches, and medical staff).

An anonymous online survey has been compiled containing quantitative and qualitative questions for sporting directors, coaches, or medical staff about their own mental health awareness and literacy. This was distributed to cycling teams and through a national-level federation. The survey link will be available online from the beginning of October 2024 to the end of February 2025. An ethical application was made to the Ethics Committee in the Canton of Bern, who determined that the research fell outside the scope of the Swiss Human Research Act and therefore did not require formal approval.

Preliminary results will be ready in March 2025 in time for the poster display at the European Congress of Psychiatry in April 2025. The findings will provide insights into mental health awareness amongst team stakeholders in men’s elite-level cycling. The quantitative data will be studied with descriptive statistics and the qualitative results will be evaluated using thematic content analysis to identify key themes.

Based on prior literature, our hypotheses are that there is limited mental health awareness about the mental health of elite-level riders amongst cycling team stakeholders and scarce knowledge about how to manage these issues should they arise. These findings would underline a need for more attention to this topic within the sport, potentially necessitating the involvement of national federations and regulators.

A. Smith: None Declared, J. Grana: None Declared, J. Colangelo: None Declared, A. Buadze: None Declared, M. Liebrenz Consultant of: In cooperation with Swiss Cycling, Michael Liebrenz provides mental health support to elite-level riders involved with the Swiss national team.

Eco-anxiety, a term that encapsulates the anxiety and distress associated with climate change and environmental degradation, has emerged as a significant psychosocial issue affecting individuals across various demographics. This phenomenon is particularly pronounced among younger generations, who often experience heightened awareness of climate-related threats and their potential impacts on future well-being. The interplay between eco-anxiety and psychosocial problems is complex, involving emotional, cognitive, and social dimensions that can significantly influence mental health outcomes. Research indicates that eco-anxiety is characterized by a future-oriented worry about the potential impacts of climate change, distinguishing it from other eco-emotions such as eco-grief and eco-despair. While many individuals experience eco-anxiety in a non-clinical form, there are instances where it can escalate to pathological levels, leading to significant mental health challenges. This is particularly relevant for young people, who may face multiple life stressors, such as academic pressures and social expectations, which can exacerbate feelings of eco-anxiety and contribute to the development of mental health issues.

In this study, the negative effects of climate change will be emphasized and its effects on human health and psychology will be emphasized. The main purpose of the study is to prepare the ground for future studies on eco-anxiety, which addresses the connection between climate change and psychology, and to increase social awareness.

The study will conduct between October 2024 and January 2025 2023 in 3 databases (PubMed, Cochrane Library, Science Direct) using the keywords “eco-anxiety” “psychosocial problems” and “mental health”. These databases were preferred because they contain a significant amount of evidence-based literature in the field of biomedical sciences and psychology. Studies conducted between 2000 and 2024, whose full texts were accessed and written in Turkish and English were included in the study.

20 national and international research articles on the subject have been reached and the literature review continues. When the literature review is finalized, all study results will be presented together.

Conclusions: In summary, eco-anxiety represents a significant psychosocial challenge that intertwines with various mental health issues. Understanding the emotional, cognitive, and social dimensions of eco-anxiety is crucial for developing effective interventions that address the mental health impacts of climate change. By fostering emotional regulation, acknowledging the role of grief, and promoting community engagement, mental health professionals can better support individuals grappling with eco-anxiety and its implications for overall well-being.

None Declared

Pathological lying, traditionally known as pseudologia fantastica or mythomania, is characterized by persistent or compulsive lying that often involves elaborate and fantastical narratives. Although the psychiatric community has yet to reach a consensus about its classification as a symptom or as a distinct diagnostic entity, emerging research about its pathophysiology highlights the involvement of complex interactions between neurobiological, psychological, and social factors.

The aim of this study is to explore, through a clinical case of an inpatient in whom pathological lying was identified, the possible causes and underlying mechanisms of this condition.

A case report presentation followed by a non-systematic review of the literature available at PubMed, ScienceDirect and ResearchGate databases, using the MeSH terms “pathological lying” OR “pseudologia fantastica” OR “mythomania”. From a total of 226 abstracts initially screened, we included 51 articles in the final review.

We report the case of a 33-year-old man with a diagnosis of Charcot-Marie-Tooth disease type 2C and comorbid depressive disorder, who was admitted to the emergency department for suicidal ideation. Collateral information from family members was crucial to identify pathological lying, in this case associated with the lack of social relationships, low self-esteem, a desire for autonomy, and poor emotional and behavioral regulation. Although standard blood workup yielded unremarkable findings, imaging studies showed an old lacunar infarction localized to the right hemithalamus. While hospitalized he presented rapid clinical improvement, being discharged with outpatient follow-up. The existing body of evidence on pathological lying fails to capture specific causal factors for this phenomenon. Research into its neurobiological basis examined abnormalities in brain areas responsible for executive functioning, impulse control, and behavioral and emotional responses, such as the prefrontal cortex, the limbic and paralimbic systems, and the right hemithalamus. From a psychological perspective, the pathological liar doesn’t have an external motive for lying; instead, the lie seems to be the purpose in itself, being unconsciously produced to fulfill the need for power and autonomy, to elevate one’s self-esteem, or to repress reality. In addition, certain environmental factors, including childhood trauma, neglect, or abuse, also seem to play a significant role in shaping this type of behavior.

The current research on the pathophysiology of pathological lying is still limited and vague, depicting a multifactorial entity that would benefit from a multidisciplinary approach integrating Psychiatry, Neurology, and Behavioral Sciences. The development of a more comprehensive conceptual model may help practitioners implement formal assessment and management strategies for people suffering from this condition.

None Declared

Despite antipsychotic treatment, around one-third of individuals of schizophrenia remain unresponsive.

Comparing cognitive impairments in TRS versus non-TRS patients.

50 adult patients with schizophrenia(DSM-5) were recruited in this cross-sectional cohort study, categorised into TRS (14) (treatment-resistant schizophrenia) and NTRS (36) (non-treatment-resistant schizophrenia) by modified Kane criteria. Positive and Negative Syndrome Scale (PANSS) and Montreal Cognitive Assessment Scale (MoCA) were used.

MoCA Scores (Table 2) are significantly lower in the TRS group, implying NTRS has a moderate cognitive decline, and TRS has severe cognitive decline. Total PANSS, Positive, Negative,and Generalised PANSS are significantly lower in the TRS group indicating severe symptoms than NTRS.Classifying based onTotal PANSS Score, the TRS has severely ill, while the NTRS has borderline mentally ill patients. The composite score indicates that the TRS group tends to have more negative symptoms. Computing the data’s variances and independent sample Welch’s t-test (Image 3) for data with unequal variances and independent sample student’s test (Images 1, 2) for data with equal variances were performed. Age does not significantly affect TRS(Table 1). Duration of illness is significantly higher in the TRS group. MoCA domains (i.e., executive function, visuospatial, orientation, and attention) except memory and language have significantly lower scores in the TRS group. Positive symptoms (conceptual disorganisation, excitement,grandiosity, suspicion, and hostility) except delusion and hallucinatory behaviour were significantly higher in the TRS group. Negative symptoms (emotional withdrawal, poor rapport, passive/apathetic social withdrawal, difficulty in abstract thinking, lack of spontaneity and flow of conversation, stereotype thinking) except blunted effect were significantly higher in the TRS group. Generalised symptoms (somatic concern, anxiety, guilt feelings, mannerism and posture, depression, motor retardation, uncooperativeness, unusual thought content, social disorientation, poor attention, lack of judgement, disturbance of volition, poor impulse control, preoccupation, and active social avoidance) except tension were significantly higher in the TRS group.

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TRS patients show severe cognitive impairment, however it does not impact language and memory. TRS shows more symptom severity except delusion, hallucinatory behaviour, blunted effect, and tension as compared to NTRS.

None Declared

Work-related hand injuries (WRHI) can have profound impacts on an individual’s physical capabilities, and these injuries often carry long-term consequences that extend beyond physical impairment. Upon returning to work, victims may face challenges in performing occupational tasks and daily activities.

This study aims to assess the quality of life in workers who have suffered WRHI after returning to their professional activities.

We conducted a cross-sectional study among victims of WRHI in the private sector after returning to work, from January 2021 to December 2022. Sociodemographic and professional data were collected along with characteristics of the WRHI. Quality of life was assessed using the Short Form-12 (SF-12) score, which evaluates both physical and mental health components (PCS-12 and MCS-12). The Quick Disabilities of the Arm, Shoulder, and Hand (Quick DASH) score was used to measure the functional disability of the hand. Job satisfaction and pain level were auto-evaluated with a scale of 0 to 10.

We included 126 workers, 88.1% of whom were male, with a mean age of 41.3 ± 10.6 years. Tobacco and alcohol use were reported by 42.9% and 9.5% of participants, respectively, while caffeine consumption was noted in 57.9%. The most represented sectors were metallurgy (22.2%) and the chemical industry (16.7%). The median job satisfaction after the accident was 6 (IQR [5; 8]). In 61.9% of cases, the dominant hand was affected. Both rehabilitation sessions and surgical treatment were required for 69% of participants. The median pain level was 5 (IQR [4; 7]), and 47.6% of participants reported sleep disorders following the accident.

The median Quick DASH score was 34.1 (IQR [13.1; 50.6]), and the median Quick DASH work module score was 43.8 (IQR [25; 68.8]). The mean PCS-12 score was 39.5 ± 7.6, while the mean MCS-12 score was 46.8 ± 11.4. The PCS-12 score was significantly associated with caffeine consumption (p = 0.03), alcohol consumption (p = 0.03), rehabilitation sessions (p = 0.029), and sleep disorders (p < 0.001). It was also significantly correlated with pain level (p = 0.005; r = -0.247), Quick DASH score (p < 0.001; r = -0.4), and the Quick DASH work module (p < 0.001; r = -0.44).

The MCS-12 score was significantly associated with job satisfaction (p = 0.008; r = 0.237), Quick DASH score (p = 0.003; r = -0.265), the Quick DASH work module (p = 0.012; r = -0.23), and sleep disorders (p = 0.012).

Work-related injuries, particularly hand injuries, pose significant challenges to both the professional and personal lives of those affected. Addressing these challenges is crucial to ensuring a successful return to work and social reintegration.

None Declared

Anesthesia technicians play a crucial role in operating room ensuring the conduct of anesthesia procedures and monitoring patients. However, the demanding nature of their work involving irregular hours, alertness, extended hours in addition to the exposure to anesthetic agents may influence their performance and vigilance.

The aim of this study was to assess signs of sleepiness among anesthesia technicians (AT) and evaluate its associated factors.

We conducted a cross-sectional study among AT in two University Hospitals in Sfax, Tunisia, between January and July 2024 during periodic health assessment visits. Sociodemographic and professional data were collected. The Epworth Sleepiness Scale (ESS) was used to assess signs of sleepiness.

Our population consisted of 60 AT with a mean age of 47.9±7.1 years. Two participants (3.3%) were males. The mean seniority was 24±7.5 years in healthcare and 10.4±8.1 years in the current ward. Forty-five AT (75%) reported using Halogenated Anesthetics. Ninety-five percent of the population had shift work. Fatigue and daytime somnolence were reported by 73.3% and 45% of the population respectively. The median ESS score was 6 Interquartile range IQR [2.25;6]. Excessive sleepiness was found in 21.7% of the population. The ESS score was higher among AT who used halogenated anesthetic, but no significant association was found (p=0.2) in the bivariate analysis.

Assessing vigilance among AT is necessary to maintain patient safety. Organizational factors such as long hours and environmental factors such as effective evacuation system for halogenated agents could cause fatigue and sleepiness in operating room.

None Declared

Work-related hand injuries can lead to significant physical impairments. However, their psychological impact is often underestimated. Mental distress, including anxiety, depression, and post-traumatic stress, may arise following such injuries, potentially hindering recovery and affecting both professional and personal life. Given the critical importance of hand function in daily tasks and occupational roles and the prevalence of hand injuries, addressing their psychological dimension is crucial.

This study aims to evaluate mental distress among individuals with work-related hand injuries (WRHI) and to identify the associated factors.

We conducted a cross-sectional study, between January 2021 to December 2022, involving private sector workers, victims of WRHI. Data were collected using a pre-established questionnaire that covered sociodemographic and professional characteristics, details of the occupational accident, and medical information. Psychological distress was assessed using the Kessler Psychological Distress Scale (K6), and functional disability of the hand was evaluated using the Quick Disabilities of the Arm, Shoulder, and Hand (Quick DASH) score.

Our study included 136 workers, with a male-to-female ratio of 7.5. The average age was 41.2 ± 10.9 years, and the average body mass index (BMI) was 26.48 ± 4.4. Blue-collar workers made up 77.9% of the sample (n = 106). In 61.8% of cases, the injury involved the dominant hand. The median of time to return to work was 101.5 days (interquartile range (IQR) [67; 182.5]). Twenty-five participants (18.4%) reported discrimination at the workplace. The median of the Quick DASH score was 34.1 (IQR [13.6; 52.3]). The median K6 score was 8 (IQR [4; 15]), with 42 participants (30.9%) experiencing moderate psychological distress and 45 (33.1%) reporting severe psychological distress. The K6 score showed a significant correlation with the Quick DASH score (p < 0.001, r = 0.297), BMI (p = 0.031, r = 0.185), and time to return to work (p = 0.005, r = 0.241). Those with injuries to the dominant hand had higher K6 scores compared to those with non-dominant hand injuries (p = 0.043). Furthermore, the K6 score was associated with reports of workplace discrimination following the accident.

Work-related hand injuries not only lead to physical impairments but also have a considerable psychological impact. These findings highlight the importance of comprehensive rehabilitation programs that address both the physical and psychological aspects of recovery to improve outcomes and support reintegration into the workforce.

None Declared

In the health field, healthcare workers (HCWs) need to be fulfilled to improve the quality of care. The mental health of these workers can affect the practice of their lifestyle habits.

Our study aims to assess the relationship between mental health and lifestyle habits among HCWs.

We conducted a descriptive, analytical and cross-sectional survey among HCWs using a self-administrated questionnaire. We collected socio-professional data. We assessed mental health using the depression anxiety and stress scale (DASS 21).

Our study included 200 healthcare workers, 71% of whom were female. The average age of participants was 42.9 years, with an average job tenure of 14.2 ± 10.1 years. We found that 12.5% of participants were smokers, 5% were former smokers, and 20.5% were passive smokers. Three participants were alcoholics, and none used drugs or chewed Neffa. Additionally, 32% of the population engaged in sports, with an average duration of 4.5 ± 2.9 hours per week.

According to the DASS21, 63% of participants exhibited symptoms suggestive of anxiety, 65.5% showed signs of stress, and 39.5% had depressive symptoms. We found that participation in sporting activities was associated with reduced anxiety (p = 0.04).

Our findings highlight a correlation between reduced anxiety and practicing sporting activities. It is crucial to encourage HCWs to maintain regular physical activity to promote an active lifestyle, reduce stress and improve mood in order to enhance the quality of care.

None Declared

Nurses play a crucial role in patient care. Indeed, this profession requires a high level of emotional, mental and physical workload. Improving the well-being of these workers means taking into account the impact of workload on their job satisfaction.

Our study aims to assess the relationship between perceived workload and job satisfaction among nurses.

We conducted a descriptive, analytical and cross-sectional survey among nurses using a self-administrated questionnaire. We collected socio-professional data. We assessed perceived workload using the National Aeronautics and Space Administration Task Load Index (NASA-TLX). Job satisfaction was evaluated using the single-item measure of job satisfaction.

Our population comprised 202 nurses, 67% of whom were female. The mean age of participants was 35.1 ± 8.1 years. The nurses’ length of service in the department was 6.9 ±7.5 years. The mean score of mental demand, physical demand, performance, effort, frustration level and temporal demand were respectively 77.8±22.6, 76.9±23.5, 67.9±31.9, 81.4±20, 66.6±25.2 and 59.8±30.2. The mean score of Raw TLX was 71.44 ±14.8. Among our participants, 74 (37%) were satisfied with their jobs. We found that the job satisfaction was positively correlated with the overall RAW TLX score (p=0.02) and with the physical (p=0.04) and temporal (p=0.00) demands.

Our findings highlight a correlation between high perceived workload and job dissatisfaction. Therefore, it is crucial to assess and improve working conditions to ensure a safe, comfortable and well-equipped environment, thus promoting nurses’ satisfaction and quality of care.

None Declared

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, disorganization, and/or hyperactivity-impulsivity. It is associated with cognitive deficits and functional impairments. A frequent cognitive impairment, likely related to hypofunctioning of the prefrontal cortex and its connections, involves executive functions, a set of skills related to self-control and goal-directed activities. The disorder also significantly affects quality of life, being associated, for example, with higher unemployment, relationship problems, and lower average income compared to individuals without the disorder.

To investigate the performance in executive functions and quality of life in individuals with ADHD compared to a control group, and to relate these with the severity of symptoms.

Forty individuals aged 18-50 participated, including 10 with an ADHD diagnosis and 30 controls matched for sex, age, and education in a case-control design (3 controls per case). Measures included: a) the Adult Self-Report Scale (ASRS) with 18 items, based on the DSM criteria for ADHD (total score used); b) the computerized Stroop Test (Victoria version) to assess executive functions, with three phases: reading words in black (control 1), naming colors in circles (control 2), and naming colors in words while inhibiting reading (incongruent phase). Reaction times for each part and interference times (part 3 minus part 2) were calculated; c) the WHOQOL questionnaire, assessing quality of life across four domains (physical, psychological, social relationships, and environment), with domain scores used. Given data normality, Student’s t-tests compared group means.

ADHD participants had significantly poorer executive functions, with longer reaction times in the Stroop Test part 3 (M = 1.05; SD = .63) compared to controls (M = .69; SD = .32), and higher interference reaction times (M = .28; SD = .34 for ADHD) compared to controls (M = .10; SD = .16). ADHD individuals also reported lower quality of life in social relationships (WHOQOL Domain 3) (M = 3.3, SD = .76) compared to controls (M = 3.8; SD = .65). Significant correlations indicated that more ASRS symptoms were associated with longer reaction times in Stroop Test parts 2 and 3, higher interference reaction times, and lower quality of life in social relationships.

The study highlights deficits in executive functions, particularly inhibition in incongruent situations, and reduced quality of life, especially in social relationships, in individuals with ADHD. These impairments correlate with the severity of symptoms, emphasizing the need to address executive function disturbances and quality of life in ADHD treatment.

None Declared

The behavioral variant of frontotemporal neurocognitive disorder is the most common clinical syndrome within frontotemporal neurocognitive disorders and is primarily characterized by progressive changes in personality and behavior. Due to the heterogeneity of this condition and the lack of sensitive and specific complementary tests, patients are often misdiagnosed with a psychiatric disorder.

To describe the clinical case of a patient with a long-standing history of psychiatric pathology who was admitted to the short-stay psychiatric unit due to newly emerged behavioral disturbances, and to conduct a brief review of the literature.

Case description and literature review.

A 57-year-old male under psychiatric follow-up for Obsessive-Compulsive Disorder, impulse control disorder (kleptomania), and anxiety-depressive symptoms was voluntarily admitted to the short-stay psychiatric unit due to behavioral disturbances. During admission, the patient reported emotional dysregulation, experiencing irritability and difficulties with emotional containment and inhibition, noting feelings of impulsive discontrol and behavioral disinhibition. The family observed changes in the patient’s personality over the past months, describing him as aggressive and inappropriate.

Basic complementary tests (blood analysis, urine analysis, and toxicology screening) showed no significant alterations. Brain MRI revealed subtle signs of cortico-subcortical atrophy, predominantly in the frontotemporal regions. Cognitive assessments, including the Mini Mental State Examination, Frontal Assessment Battery and Montreal Cognitive Assessment, indicated deficits suggestive of frontal impairment. The patient had been admitted one month prior due to possible hypomanic symptoms that resolved following pharmacological adjustment, leading to a proposed diagnosis of late-onset Bipolar Disorder Type II. However, after detailed history-taking with family members and additional testing, the diagnosis leaned more towards a frontal syndrome (possible behavioral variant of frontotemporal neurocognitive disorder).

The diagnosis of frontotemporal neurocognitive disorder remains a significant challenge, partly due to the limitations of complementary tests in the early stages of the disease, with diagnosis primarily based on clinical evaluation. Consequently, many patients with frontotemporal neurocognitive disorder initially receive a diagnosis of a psychiatric condition (more frequently if the patient has a personal history of psychiatric issues). Therefore, it is crucial to understand these differences, especially in the early phases of the disease, and to continue investigating new diagnostic modalities.

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It has long been believed that a correlation exists between mental illness and artistic ability. This idea dates to antiquity, with Aristotle famously stating, “No great mind has existed without a touch of madness”. Recent studies suggest that writers and artists show a higher incidence of depressive disorders (DD) and bipolar disorder (BD) compared to the general population. However, we know that not all artists suffer from mental illness, and most individuals with mental illness are neither artists nor creative geniuses. Thus, numerous questions emerge regarding the true relationship between psychopathology and creativity.

In this study, we sought to explore the correlation between psychopathology and creativity.

In this literature review, research articles on the relationship between creativity and psychopathology are presented.

There is evidence that the genetic predisposition to BD, as well as milder forms of the disorder, is associated with increased creativity. A meta-analysis of 28 studies found a significant positive correlation between the risk of bipolar disorder and creativity (r = 0.224). Mild to moderate manifestations of the disorder can often serve as a source of inspiration, driving creative work. However, this creativity only flourishes when individuals are able to channel their emotional instability and cognitive disorganization into coherent and productive forms. In contrast, severe forms of the disorder tend to inhibit creativity, largely due to impaired concentration and disorganized thinking. Regarding DD, the research presents mixed findings. Some studies suggest a link between depression and lower creativity. A meta-analysis of 39 studies found a weak negative correlation between depressive mood and creativity (r = -0.064). However, other researchers argue that both positive and negative emotions can fuel artistic creativity. The Dual Pathway to Creativity Model supports this view, proposing that creativity—defined as the generation of original and valuable ideas—arises from cognitive flexibility and cognitive persistence. According to this model, dispositional or situational factors can influence creativity by enhancing either flexibility, persistence, or both. Negative mood states, for example, may enhance creativity by fostering persistence.

The relationship between psychopathology and creativity is complex. A genetic predisposition to BD, especially in milder forms, may enhance creativity, but severe cases often impair it due to cognitive difficulties. For DD, the link to creativity is more conflicted. While depression is generally associated with reduced creativity, some models suggest both positive and negative emotions, including those from depressive states, can foster creativity by affecting cognitive flexibility and persistence. In summary, the connection between psychopathology and creativity is multifaceted, with various contributing factors.

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The CLUMP (CLinical Utility of early intervention including the 5-Step Precision Medicine (5SPM) Method) project is a translational research initiative that aims to improve adherence to antipsychotic (AP) medications and therapeutic outcomes in patients with first-episode psychosis (FEP). CLUMP seeks to apply an early intervention model of Personalised Precision Psychiatry, based on pharmacogenetics, to this clinical group. In this specific analysis, we examine time to discontinuation of the first prescribed oral AP treatments before the implementation of the CLUMP project in Salamanca, Spain, in order to determine the impact the new Personalised Precision Psychiatry model might have on it. Indeed, given the high AP treatment discontinuation rates already identified in pragmatic, randomised controlled trials including FEP patients, these data would offer additional information about such rates in real-world clinical scenarios.

1. 1. To assess time to discontinuation for the first prescribed oral AP treatments in FEP.

2. 2. To identify specific AP with higher retention rates, which might reflect better tolerability and/or effectiveness.

This study includes a consecutive, retrospective cohort of 42 patients with FEP treated immediately before the CLUMP project implementation, who were followed for at least one year. Kaplan-Meier survival analysis was used to assess AP time to discontinuation during the first year post-treatment initiation.

Table 1 (Image 1) summarises median times to discontinuation and confidence intervals (CIs) for each AP. Survival curves (Image 2 and 3) depict treatment retention trends. The overall median time to discontinuation was 36 days (95% CI: 25-153 days), suggesting an overall high early AP treatment discontinuation. Results also showed very high variability across AP, with Paliperidone (264 days) and Risperidone (72 days) having longer retention times. However, most of the sample was initiated on Risperidone (71.2%), which affects the generalisability of these results.

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Concurring with previous randomised controlled trials, we identified a high rate of early AP treatment discontinuation in FEP treated in routine clinical practice. For most patients, the first prescribed AP was discontinued within the first month post-treatment initiation. These results emphasise the need for a more personalised AP treatment choice for patients with FEP.

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The COVID-19 pandemic significantly impacted the population in Russia, particularly students, who were forced to radically restructure their daily lives rhythm due to the introduction of distance learning, more homework, increasing the share of self-education. These factors could provoke the emergence of a particular psychopathological syndrome — asthenia, which is characterised by general and mental weakness, increased exhaustion, irritability, decreased productivity of cognitive processes, decreased motivation, sleep disorders and other psychosomatic disorders. These symptoms, in turn, could be associated with changes in the student’s quality of life.

The study aimed to assess the level of asthenia among students in humanities programs and to examine the relationship between asthenia indicators and quality of life.

Data collection was conducted from January to April 2021 through a specially developed Google form. Thirty-five students at the universities of the Russian Federation took part in the study. We used MFI-20 to assess the level of asthenia, and WHOQOL-BREF to study the life quality. Both questionnaires were adapted for Russian-speaking respondents.

We found that 31% of respondents had symptoms of general asthenia, 29% had symptoms of decreased activity, 26% had symptoms of decreased motivation, 71% had symptoms of physical asthenia, and 26% had symptoms of mental asthenia. No statistically significant correlations were found between asthenia manifestations and life quality indicators. However, significant direct correlations were obtained between all quality-of-life domains, except for “microsocial support” and “social well-being”.

In the conditions of the COVID-19 second wave, most students in Russia demonstrated physical asthenia symptoms. Asthenia manifestations were not related to the student’s life quality. Students in the pandemic conditions should observe the sleep, rest regime and optimal physical activity. Among students in Russia, the microsocial aspect of life quality (relations with partners, sexual life, relations with friends) are fairly detached from the broader social context (e.g. everyday life safety, healthy physical environment, and so on).

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