Other Pathologic Processes

Section 6 - Other Pathologic Processes

Published online by Cambridge University Press: 03 September 2018

Edited by

Raymond W. Redline ,

Theonia K. Boyd and

Drucilla J. Roberts

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Raymond W. Redline: Affiliation:
Case Western Reserve University, Ohio
Theonia K. Boyd: Affiliation:
Harvard Medical School, Boston
Drucilla J. Roberts: Affiliation:
Harvard Medical School, Boston

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Type: Chapter
Information: Placental and Gestational Pathology , pp. 157 - 240

DOI: https://doi.org/10.1017/9781316848616 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2017

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References

Fried, AM. Distribution of the bulk of the normal placenta. Review and classification of 800 cases by ultrasonography. Am J Obstet Gynecol. 1978;132:675–80.CrossRef Google Scholar PubMed

Pathak, S, Hook, E, Hackett, G, et al. Cord coiling, umbilical cord insertion and placental shape in an unselected cohort delivering at term: relationship with common obstetric outcomes. Placenta. 2010;31:963–8.10.1016/j.placenta.2010.08.004CrossRef Google Scholar

Salafia, CM, Misra, DP, Yampolsky, M, et al. Allometric metabolic scaling and fetal and placental weight. Placenta. 2009;30:355–60.Google Scholar PubMed

Salafia, CM, Zhang, J, Miller, RK, et al. Placental growth patterns affect birth weight for given placental weight. Birth Defects Res A Clin Mol Teratol. 2007;79:281–8.CrossRef Google Scholar PubMed

Salafia, CM, Zhang, J, Charles, AK, et al. Placental characteristics and birthweight. Paediatr Perinat Epidemiol. 2008;22:229–39.CrossRef Google Scholar PubMed

Salafia, CM, Yampolsky, M, Shlakhter, A, et al. Variety in placental shape: when does it originate? Placenta. 2012;33:164–70.10.1016/j.placenta.2011.12.002CrossRef Google Scholar PubMed

Redline, RW, Patterson, P. Patterns of placental injury: correlations with gestational age, placental weight, and clinical diagnosis. Arch Pathol Lab Med. 1994;118:698–701.Google Scholar

Naeye, RL. Do Placental Weights Have Clinical Significance? Hum Pathol. 1987;18:387–91.10.1016/S0046-8177(87)80170-3CrossRef Google Scholar PubMed

Yong, PJ, von Dadelszen, P, McFadden, DE, et al. Placental weight in pregnancies with trisomy confined to the placenta. J Obstet Gynaecol Can. 2009;31:605–10.10.1016/S1701-2163(16)34239-6CrossRef Google Scholar PubMed

Sawady, J, Mercer, BM, Wapner, RJ, et al. The National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network Beneficial Effects of Antenatal Repeated Steroids study: impact of repeated doses of antenatal corticosteroids on placental growth and histologic findings. Am J Obstet Gynecol. 2007;197:281 e1–8.10.1016/j.ajog.2007.06.041CrossRef Google Scholar PubMed

McNamara, H, Hutcheon, JA, Platt, RW, et al. Risk factors for high and low placental weight. Paediatr Perinat Epidemiol. 2014;28:97–105.10.1111/ppe.12104CrossRef Google Scholar PubMed

Williams, LA, Evans, SF, Newnham, JP. Prospective cohort study of factors influencing the relative weights of the placenta and the newborn infant. BMJ. 1997;314:1864–8.CrossRef Google Scholar PubMed

Wallace, JM, Horgan, GW, Bhattacharya, S. Placental weight and efficiency in relation to maternal body mass index and the risk of pregnancy complications in women delivering singleton babies. Placenta. 2012;33:611–8.10.1016/j.placenta.2012.05.006CrossRef Google Scholar PubMed

McCowan, LM, Becroft, DM. Beckwith-Wiedemann syndrome, placental abnormalities, and gestational proteinuric hypertension. Obstet Gynecol. 1994;83:813–7.Google Scholar PubMed

Leon-Garcia, SM, Roeder, HA, Nelson, KK, et al. Maternal obesity and sex-specific differences in placental pathology. Placenta. 2016;38:33–40.10.1016/j.placenta.2015.12.006CrossRef Google Scholar PubMed

Eskild, A, Romundstad, PR, Vatten, LJ. Placental weight and birthweight: does the association differ between pregnancies with and without preeclampsia? Am J Obstet Gynecol. 2009;201:595 e1–5.CrossRef Google Scholar PubMed

Salafia, C. Why placental shape and vasculature matter. ObGyn News. 2016;51:6–7.Google Scholar

Misra, DP, Salafia, CM, Miller, RK, et al. Non-linear and gender-specific relationships among placental growth measures and the fetoplacental weight ratio. Placenta. 2009;30:1052–7.10.1016/j.placenta.2009.09.008CrossRef Google Scholar PubMed

Lao, TT, Wong, WM. Implications of a high placental ratio in pregnancies with appropriate-for-gestational age neonates. Gynecol Obstet Invest. 2001;52:34–7.10.1159/000052937CrossRef Google Scholar PubMed

Macdonald, EM, Natale, R, Regnault, TR, et al. Obstetric conditions and the placental weight ratio. Placenta. 2014;35:582–6.10.1016/j.placenta.2014.04.019CrossRef Google Scholar PubMed

Redline, RW, Boyd, T, Campbell, V, et al. Maternal vascular underperfusion: nosology and reproducibility of placental reaction patterns. Pediatr Dev Pathol. 2004;7:237–49.Google Scholar PubMed

Hiden, U, Glitzner, E, Hartmann, M, et al. Insulin and the IGF system in the human placenta of normal and diabetic pregnancies. J Anat. 2009;215:60–8.10.1111/j.1469-7580.2008.01035.xCrossRef Google Scholar PubMed

Roberts, DJ, Ampola, MG, Lage, JM. Diagnosis of unsuspected fetal metabolic storage disease by routine placental examination. Pediatr Pathol. 1991;11:647–56.10.3109/15513819109064796CrossRef Google Scholar PubMed

Zalel, Y, Lehavi, O, Schiff, E, et al. Shortened fetal long bones: a possible in utero manifestation of placental function. Prenat Diagn. 2002;22:553–7.10.1002/pd.364CrossRef Google Scholar

Hutcheon, JA, McNamara, H, Platt, RW, et al. Placental weight for gestational age and adverse perinatal outcomes. Obstet Gynecol. 2012;119:1251–8.10.1097/AOG.0b013e318253d3dfCrossRef Google Scholar PubMed

Shehata, F, Levin, I, Shrim, A, et al. Placenta/birthweight ratio and perinatal outcome: a retrospective cohort analysis. BJOG. 2011;118:741–7.10.1111/j.1471-0528.2011.02892.xCrossRef Google Scholar PubMed

Straughen, J, Divine, G, Perez-Avilan, G, et al. Placental predictors of childhood body size. Placenta. 2016;45:111.10.1016/j.placenta.2016.06.174CrossRef Google Scholar

Barker, DJ, Bull, AR, Osmond, C, et al. Fetal and placental size and risk of hypertension in adult life. BMJ. 1990;301:259–62.Google Scholar PubMed

Wen, X, Triche, EW, Hogan, JW, et al. Association between placental morphology and childhood systolic blood pressure. Hypertension. 2011;57:48–55.10.1161/HYPERTENSIONAHA.110.162792CrossRef Google Scholar PubMed

Risnes, KR, Romundstad, PR, Nilsen, TI, et al. Placental weight relative to birth weight and long-term cardiovascular mortality: findings from a cohort of 31,307 men and women. Am J Epidemiol. 2009;170:622–31.10.1093/aje/kwp182CrossRef Google Scholar

Kraus, FT, Redline, R, Gersell, DJ, et al. Placental Pathology. Washington, D.C.: American Registry of Pathology; 2004.10.55418/1881041891CrossRef Google Scholar

Proctor, LK, Toal, M, Keating, S, et al. Placental size and the prediction of severe early-onset intrauterine growth restriction in women with low pregnancy-associated plasma protein-A. Ultrasound Obstet Gynecol. 2009;34:274–82.CrossRef Google Scholar PubMed

Kajantie, E, Thornburg, KL, Eriksson, JG, et al. In preeclampsia, the placenta grows slowly along its minor axis. Int J Dev Biol. 2009;54:469–73.Google Scholar

Endler, M, Saltvedt, S, Papadogiannakis, N. Macroscopic and histological characteristics of retained placenta: A prospectively collected case-control study. Placenta. 2016;41:39–44.10.1016/j.placenta.2016.02.013CrossRef Google Scholar PubMed

Costantini, D, Walker, M, Milligan, N, et al. Pathologic basis of improving the screening utility of 2-dimensional placental morphology ultrasound. Placenta. 2012;33:845–9.10.1016/j.placenta.2012.07.010CrossRef Google Scholar PubMed

Jauniaux, E, Hempstock, J, Greenwold, N, et al. Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies. Am J Pathol. 2003;162:115–25.CrossRef Google Scholar PubMed

Alwasel, SH, Abotalib, Z, Aljarallah, JS, et al. The breadth of the placental surface but not the length is associated with body size at birth. Placenta. 2012;33:619–22.10.1016/j.placenta.2012.04.015CrossRef Google Scholar

Yampolsky, M, Salafia, CM, Misra, DP, et al. Is the placental disk really an ellipse? Placenta. 2013;34:391–3.10.1016/j.placenta.2012.12.002CrossRef Google Scholar

Eriksson, JG, Kajantie, E, Thornburg, KL, et al. Mother’s body size and placental size predict coronary heart disease in men. Eur Heart J. 2011;32:2297–303.10.1093/eurheartj/ehr147CrossRef Google Scholar PubMed

Eriksson, JG, Kajantie, E, Osmond, C, et al. Boys live dangerously in the womb. Am J Hum Biol. 2010;22:330–5.CrossRef Google Scholar PubMed

Jauniaux, E, Ramsay, B, Campbell, S. Ultrasonographic investigation of placental morphologic characteristics and size during the second trimester of pregnancy. Am J Obstet Gynecol. 1994;170:130–7.10.1016/S0002-9378(13)70293-XCrossRef Google Scholar PubMed

Eriksson, JG, Gelow, J, Thornburg, KL, et al. Long-term effects of placental growth on overweight and body composition. Int J Pediatr. 2012;2012:324185.CrossRef Google Scholar PubMed

van Abeelen, AF, de Rooij, SR, Osmond, C, et al. The sex-specific effects of famine on the association between placental size and later hypertension. Placenta. 2011;32:694–8.10.1016/j.placenta.2011.06.012CrossRef Google Scholar PubMed

Barker, DJ, Osmond, C, Thornburg, KL, et al. The lifespan of men and the shape of their placental surface at birth. Placenta. 2011;32:783–7.10.1016/j.placenta.2011.07.031CrossRef Google Scholar PubMed

Fitzgerald, B, Kingdom, J, Keating, S. Distal villous hypoplasia. Diagn Histopathol. 2012;18 (5):195–200.10.1016/j.mpdhp.2012.02.005CrossRef Google Scholar

Porat, S, Fitzgerald, B, Wright, E, et al. Placental hyperinflation and the risk of adverse perinatal outcome. Ultrasound Obstet Gynecol. 2013;42:315–21.10.1002/uog.12386CrossRef Google Scholar PubMed

Raio, L, Ghezzi, F, Cromi, A, et al. The thick heterogeneous (jellylike) placenta: a strong predictor of adverse pregnancy outcome. Prenat Diagn. 2004;24:182–8.10.1002/pd.828CrossRef Google Scholar

Blackburn, W, Cooley, NR. The Umbilical Cord. In: Stevenson, RE, Hall, JG, Goodman, RM, editors. Human Malformations and Related Anomalies. New York, NY: Oxford University Press; 1993.Google Scholar

Fox, H. Pathology of the Placenta. 2nd ed. London, UK: W. B. Saunders; 1997.Google Scholar

Catanzarite, V, Cousins, L, Daneshmand, S, et al. Prenatally Diagnosed Vasa Previa: A Single-Institution Series of 96 Cases. Obstet Gynecol. 2016;128:1153–61.10.1097/AOG.0000000000001680CrossRef Google Scholar PubMed

Hertig, A. Human Trophoblast. Springfield, IL: C. C. Thomas; 1968.Google Scholar

Benirschke, K, Burton, G, Baergen, RN, editors. Pathology of the Human Placenta. 6th ed. New York, NY: Springer; 2012.CrossRef Google Scholar

Schwartz, N, Mandel, D, Shlakhter, O, et al. Placental morphologic features and chorionic surface vasculature at term are highly correlated with 3-dimensional sonographic measurements at 11 to 14 weeks. J Ultrasound Med. 2011;30:1171–8.CrossRef Google Scholar PubMed

Yampolsky, M, Salafia, CM, Shlakhter, O, et al. Modeling the variability of shapes of a human placenta. Placenta. 2008;29:790–7.10.1016/j.placenta.2008.06.005CrossRef Google Scholar PubMed

Ahmed, A, Gilbert-Barness, E. Placenta membranacea: a developmental anomaly with diverse clinical presentation. Pediatr Dev Pathol. 2003;6:201–2.10.1007/s10024-002-0007-zCrossRef Google Scholar PubMed

Greenberg, JA, Sorem, KA, Shifren, JL, et al. Placenta membranacea with placenta increta: a case report and literature review. Obstet Gynecol. 1991;78:512–4.Google Scholar PubMed

Heras, JL, Harding, PG, Haust, MD. Recurrent bleeding associated with placenta membranacea partialis: report of a case. Am J Obstet Gynecol. 1982;144:480–2.Google Scholar PubMed

Luo, G, Redline, RW. Peripheral insertion of umbilical cord. Pediatr Dev Pathol. 2013;16:399–404.10.2350/13-05-1337-OA.1CrossRef Google Scholar PubMed

Raisanen, S, Georgiadis, L, Harju, M, et al. Risk factors and adverse pregnancy outcomes among births affected by velamentous umbilical cord insertion: a retrospective population-based register study. Eur J Obstet Gynecol Reprod Biol. 2012;165:231–4.CrossRef Google Scholar PubMed

Heinonen, S, Ryynanen, M, Kirkinen, P, et al. Elevated midtrimester maternal serum hCG in chromosomally normal pregnancies is associated with preeclampsia and velamentous umbilical cord insertion. Am J Perinatol. 1996;13:437–41.10.1055/s-2007-994384CrossRef Google Scholar PubMed

Heinonen, S, Ryynanen, M, Kirkinen, P, et al. Velamentous umbilical cord insertion may be suspected from maternal serum alpha-fetoprotein and hCG. Br J Obstet Gynaecol. 1996;103:209–13.10.1111/j.1471-0528.1996.tb09707.xCrossRef Google Scholar PubMed

Heinonen, S, Ryynanen, M, Kirkinen, P, et al. Perinatal diagnostic evaluation of velamentous umbilical cord insertion: clinical, Doppler, and ultrasonic findings. Obstet Gynecol. 1996;87:112–7.10.1016/0029-7844(95)00339-8CrossRef Google Scholar PubMed

Redline, R, Shah, D, Sakar, H, et al. Placental lesions associated with abnormal growth in twins. Pediat and Devel Pathol. 2001;4:473–81.Google Scholar PubMed

Costa-Castro, T, Zhao, DP, Lipa, M, et al. Velamentous cord insertion in dichorionic and monochorionic twin pregnancies – Does it make a difference? Placenta. 2016;42:87–92.10.1016/j.placenta.2016.04.007CrossRef Google Scholar

Robinson, LK, Jones, KL, Benirschke, K. The nature of structural defects associated with velamentous and marginal insertion of the umbilical cord. Am J Obstet Gynecol. 1983;146:191–3.10.1016/0002-9378(83)91052-9CrossRef Google Scholar PubMed

Gordon, Z, Eytan, O, Jaffa, AJ, et al. Fetal blood flow in branching models of the chorionic arterial vasculature. Ann N Y Acad Sci. 2007;1101:250–65.10.1196/annals.1389.037CrossRef Google Scholar PubMed

Nordenvall, M, Sandstedt, B, Ulmsten, U. Relationship between placental shape, cord insertion, lobes and gestational outcome. Acta Obstet Gynecol Scand. 1988;67:611–6.CrossRef Google Scholar PubMed

Hasegawa, J, Matsuoka, R, Ichizuka, K, et al. Cord insertion into the lower third of the uterus in the first trimester is associated with placental and umbilical cord abnormalities. Ultrasound Obstet Gynecol. 2006;28:183–6.10.1002/uog.2839CrossRef Google Scholar PubMed

Proctor, LK, Fitzgerald, B, Whittle, WL, et al. Umbilical cord diameter percentile curves and their correlation to birth weight and placental pathology. Placenta. 2013;34:62–6.10.1016/j.placenta.2012.10.015CrossRef Google Scholar PubMed

Redline, RW. Clinical and pathological umbilical cord abnormalities in fetal thrombotic vasculopathy. Hum Pathol. 2004;35:1494–8.10.1016/j.humpath.2004.08.003CrossRef Google Scholar PubMed

Swank, ML, Garite, TJ, Maurel, K, et al. Vasa previa: diagnosis and management. Am J Obstet Gynecol. 2016;215:223 e1–6.10.1016/j.ajog.2016.02.044CrossRef Google Scholar PubMed

Baergen, RN, Malicki, D, Behling, C, et al. Morbidity, mortality, and placental pathology in excessively long umbilical cords: retrospective study. Pediatr Dev Pathol. 2001;4:144–53.10.1007/s100240010135CrossRef Google Scholar PubMed

Rayburn, WF, Beynen, A, Brinkman, DL. Umbilical cord-length and intrapartum complications. Obstet Gynecol. 1981;57:450–2.Google Scholar PubMed

Miller, ME, Higginbottom, M, Smith, DW. Short umbilical cord: its origin and relevance. Pediatrics. 1981;67:618–21.10.1542/peds.67.5.618CrossRef Google Scholar PubMed

LaMonica, GE, Wilson, ML, Fullilove, AM, et al. Minimum cord length that allows spontaneous vaginal delivery. J Reprod Med. 2008;53:217–9.Google Scholar PubMed

Raio, L, Ghezzi, F, Di Naro, E, et al. Prenatal diagnosis of a lean umbilical cord: a simple marker for the fetus at risk of being small for gestational age at birth. Ultrasound Obstet Gynecol. 1999;13:176–80.10.1046/j.1469-0705.1999.13030176.xCrossRef Google Scholar PubMed

Raio, L, Ghezzi, F, Di Naro, E, et al. Altered sonographic umbilical cord morphometry in early-onset preeclampsia. Obstet Gynecol. 2002;100:311–6.Google Scholar PubMed

Roche, N, Skurnick, J, Brown, K, et al. Do stillborns with no identifiable pathology have leaner cords than liveborns? J Reprod Med. 2008;53:283–6.Google Scholar PubMed

Casola, G, Scheible, W, Leopold, GR. Large umbilical cord: a normal finding in some fetuses. Radiology. 1985;156:181–2.CrossRef Google Scholar PubMed

Moessinger, AC, Blanc, WA, Merone, PA, et al. Umbilical cord length as an index of fetal activity: experimental study and clinical implications. Pediatr Res. 1982;16:109–12.10.1203/00006450-198202000-00006CrossRef Google Scholar

Georgiadis, L, Keski-Nisula, L, Harju, M, et al. Umbilical cord length in singleton gestations: a Finnish population-based retrospective register study. Placenta. 2014;35:275–80.10.1016/j.placenta.2014.02.001CrossRef Google Scholar PubMed

Cardoso, LE, Erlich, RB, Rudge, MC, et al. A comparative analysis of glycosaminoglycans from human umbilical arteries in normal subjects and in pathological conditions affecting pregnancy. Lab Invest. 1992;67:588–95.Google Scholar PubMed

Mills, JL, Harley, EE, Moessinger, AC. Standards for measuring umbilical cord length. Placenta. 1983;4:423–6.10.1016/S0143-4004(83)80045-9CrossRef Google Scholar PubMed

Downey, A, Hore, K, McAuliffe, FM, et al. Umbilical cord shortening: quantification postdelivery and postfixation. Pediatr Dev Pathol. 2014;17:327–9.10.2350/14-02-1437-OA.1CrossRef Google Scholar PubMed

Chang, KT, Keating, S, Costa, S, et al. Third-trimester stillbirths: correlative neuropathology and placental pathology. Pediatr Dev Pathol. 2011;14:345–52.CrossRef Google Scholar PubMed

Strong, TH Jr., Jarles, DL, Vega, JS, et al. The umbilical coiling index. Am J Obstet Gynecol. 1994;170:29–32.10.1016/S0002-9378(13)70274-6CrossRef Google Scholar PubMed

Peng, HQ, Levitin-Smith, M, Rochelson, B, et al. Umbilical cord stricture and overcoiling are common causes of fetal demise. Pediatr Dev Pathol. 2006;9:14–9.10.2350/05-05-0051.1CrossRef Google Scholar PubMed

Machin, GA, Ackerman, J, Gilbert-Barness, E. Abnormal umbilical cord coiling is associated with adverse perinatal outcomes. Pediatr Dev Pathol. 2000;3:462–71.10.1007/s100240010103CrossRef Google Scholar PubMed

de Laat, MW, Franx, A, Bots, ML, et al. Umbilical coiling index in normal and complicated pregnancies. Obstet Gynecol. 2006;107:1049–55.10.1097/01.AOG.0000209197.84185.15CrossRef Google Scholar PubMed

Ernst, LM, Minturn, L, Huang, MH, et al. Gross patterns of umbilical cord coiling: Correlations with placental histology and stillbirth. Placenta. 2013;34:583–8.10.1016/j.placenta.2013.04.002CrossRef Google Scholar PubMed

Lacro, RV, Jones, KL, Benirschke, K. The umbilical cord twist: origin, direction, and relevance. Am J Obstet Gynecol. 1987;157:833–8.CrossRef Google Scholar PubMed

Rana, J, Ebert, GA, Kappy, KA. Adverse perinatal outcome in patients with an abnormal umbilical coiling index. Obstet Gynecol. 1995;85:573–7.10.1016/0029-7844(94)00435-GCrossRef Google Scholar PubMed

Degani, S, Lewinsky, RM, Berger, H, et al. Sonographic estimation of umbilical coiling index and correlation with Doppler flow characteristics. Obstet Gynecol. 1995;86:990–3.10.1016/0029-7844(95)00307-DCrossRef Google Scholar PubMed

Cromi, A, Ghezzi, F, Durig, P, et al. Sonographic umbilical cord morphometry and coiling patterns in twin-twin transfusion syndrome. Prenat Diagn. 2005;25:851–5.10.1002/pd.1273CrossRef Google Scholar PubMed

Sun, Y, Arbuckle, S, Hocking, G, et al. Umbilical cord stricture and intrauterine fetal death. Pediatr Pathol Lab Med. 1995;15:723–32.10.3109/15513819509027008CrossRef Google Scholar PubMed

French, AE, Gregg, VH, Newberry, Y, et al. Umbilical cord stricture: a cause of recurrent fetal death. Obstet Gynecol. 2005;105:1235–9.10.1097/01.AOG.0000159041.55845.f7CrossRef Google Scholar PubMed

Rodriguez, JI, Marino-Enriquez, A, Suarez-Aguado, J, et al. Umbilical cord stricture is not a genetic anomaly: a study in twins. Pediatr Dev Pathol. 2008;11:363–9.10.2350/07-08-0329.1CrossRef Google Scholar

de Laat, MW, Nikkels, PG, Franx, A, et al. The Roach muscle bundle and umbilical cord coiling. Early Hum Dev. 2007;83:571–4.10.1016/j.earlhumdev.2006.12.003CrossRef Google Scholar PubMed

Georgiou, HM, Rice, GE, Walker, SP, et al. The effect of vascular coiling on venous perfusion during experimental umbilical cord encirclement. Am J Obstet Gynecol. 2001;184:673–8.10.1067/mob.2001.110295CrossRef Google Scholar PubMed

Skulstad, SM, Kiserud, T, Rasmussen, S. Degree of fetal umbilical venous constriction at the abdominal wall in a low-risk population at 20–40 weeks of gestation. Prenat Diagn. 2002;22:1022–7.CrossRef Google Scholar

Blickstein, I, Varon, Y, Varon, E. Implications of differences in coiling indices at different segments of the umbilical cord. Gynecol Obstet Invest. 2001;52:203–6.10.1159/000052974CrossRef Google Scholar PubMed

de Laat, MW, van der Meij, JJ, Visser, GH, et al. Hypercoiling of the umbilical cord and placental maturation defect: associated pathology? Pediatr Dev Pathol. 2007;10:293–9.10.2350/06-01-0015.1CrossRef Google Scholar PubMed

Redline, RW. Cerebral palsy in term infants: a clinicopathologic analysis of 158 medicolegal case reviews. Pediatr Dev Pathol. 2008;11:456–64.10.2350/08-05-0468.1CrossRef Google Scholar PubMed

Weber, MA, Sau, A, Maxwell, DJ, et al. Third trimester intrauterine fetal death caused by arterial aneurysm of the umbilical cord. Pediatr Dev Pathol. 2007;10:305–8.10.2350/06-07-0136.1CrossRef Google Scholar PubMed

Bendon, RW, Tyson, RW, Baldwin, VJ, et al. Umbilical cord ulceration and intestinal atresia: a new association? Am J Obstet Gynecol. 1991;164:582–6.10.1016/S0002-9378(11)80026-8CrossRef Google Scholar PubMed

Ichinose, M, Takemura, T, Andoh, K, et al. Pathological analysis of umbilical cord ulceration associated with fetal duodenal and jejunal atresia. Placenta. 2010;31:1015–8.10.1016/j.placenta.2010.08.005CrossRef Google Scholar PubMed

Qureshi, F, Jacques, SM. Marked segmental thinning of the umbilical cord vessels. Arch Pathol Lab Med. 1994;118:826–30.Google Scholar PubMed

Labarrere, C, Sebastiani, M, Siminovich, M, et al. Absence of Wharton’s jelly around the umbilical arteries: an unusual cause of perinatal mortality. Placenta. 1985;6:555–9.10.1016/S0143-4004(85)80010-2CrossRef Google Scholar PubMed

Collins, JH, Collins, CL, Collins, CC. Umbilical Cord Accidents 2010. pregnancyinst.com/UmbilicalCordAccidents2.pdf Google Scholar

Sentilhes, L, Vivet-Lefebure, A, Patrier, S, et al. Umbilical artery aneurysm in a severe growth-restricted fetus with normal karyotype. Prenat Diagn. 2007;27:1059–61.10.1002/pd.1817CrossRef Google Scholar

Wang, G, Bove, KE, Stanek, J. Pathological evidence of prolonged umbilical cord encirclement as a cause of fetal death. Am J Perinatol. 1998;15:585–8.10.1055/s-2007-994065CrossRef Google Scholar PubMed

King, EL, Redline, RW, Smith, SD, et al. Myocytes of chorionic vessels from placentas with meconium associated vascular necrosis exhibit apoptotic markers. Hum Pathol. 2004;35:412–7.10.1016/j.humpath.2003.12.002CrossRef Google Scholar PubMed

Froehlich, LA, Fujikura, T. Significance of a single umbilical artery. Report from the collaborative study of cerebral palsy. Am J Obstet Gynecol. 1966;94:274–9.10.1016/0002-9378(66)90476-5CrossRef Google Scholar

Khong, TY, George, K. Chromosomal abnormalities associated with a single umbilical artery. Prenat Diagn. 1992;12:965–8.10.1002/pd.1970121118CrossRef Google Scholar PubMed

Murphy-Kaulbeck, L, Dodds, L, Joseph, KS, et al. Single umbilical artery risk factors and pregnancy outcomes. Obstet Gynecol. 2010;116:843–50.10.1097/AOG.0b013e3181f0bc08CrossRef Google Scholar PubMed

Martinez-Frias, ML, Bermejo, E, Rodriguez-Pinilla, E, et al. Does single umbilical artery (SUA) predict any type of congenital defect? Clinical-epidemiological analysis of a large consecutive series of malformed infants. Am J Med Genet A. 2008;146A:15–25.10.1002/ajmg.a.31911CrossRef Google Scholar PubMed

Battarbee, AN, Palatnik, A, Ernst, LM, et al. Association of Isolated Single Umbilical Artery With Small for Gestational Age and Preterm Birth. Obstet Gynecol. 2015;126:760–4.CrossRef Google Scholar PubMed

Dolkart, LA, Reimers, FT, Kuonen, CA. Discordant umbilical arteries: ultrasonographic and Doppler analysis. Obstet Gynecol. 1992;79:59–63.Google Scholar PubMed

Raio, L, Ghezzi, F, di Naro, E, et al. In-utero characterization of the blood flow in the Hyrtl anastomosis. Placenta. 2001;22:597–601.10.1053/plac.2001.0685CrossRef Google Scholar PubMed

Gamzu, R, Zalel, Y, Jacobson, JM, et al. Type II single umbilical artery (persistent vitelline artery) in an otherwise normal fetus. Prenat Diagn. 2002;22:1040–3.10.1002/pd.463CrossRef Google Scholar

Bourke, WG, Clarke, TA, Mathews, TG, et al. Isolated single umbilical artery–the case for routine renal screening. Arch Dis Child. 1993;68:600–1.10.1136/adc.68.5_Spec_No.600CrossRef Google Scholar PubMed

Fortune, DW, Ostor, AG. Angiomyxomas of the umbilical cord. Obstet Gynecol. 1980;55:375–8.10.1097/00006250-198003000-00022CrossRef Google Scholar PubMed

Kilicdag, EB, Kilicdag, H, Bagis, T, et al. Large pseudocyst of the umbilical cord associated with patent urachus. J Obstet Gynaecol Res. 2004;30:444–7.10.1111/j.1447-0756.2004.00228.xCrossRef Google Scholar PubMed

Schaefer, IM, Manner, J, Faber, R, et al. Giant umbilical cord edema caused by retrograde micturition through an open patent urachus. Pediatr Dev Pathol. 2010;13:404–7.10.2350/09-10-0731-CR.1CrossRef Google Scholar PubMed

Sepulveda, W, Gutierrez, J, Sanchez, J, et al. Pseudocyst of the umbilical cord: prenatal sonographic appearance and clinical significance. Obstet Gynecol. 1999;93:377–81.Google Scholar PubMed

Yavner, DL, Redline, RW. Angiomyxoma of the umbilical cord with massive cystic degeneration of Wharton’s jelly. Arch Pathol Lab Med. 1989;113:935–7.Google Scholar PubMed

Jauniaux, E, De Munter, C, Vanesse, M, et al. Embryonic remnants of the umbilical cord: morphologic and clinical aspects. Hum Pathol. 1989;20:458–62.10.1016/0046-8177(89)90011-7CrossRef Google Scholar PubMed

Vougiouklakis, T, Mitselou, A, Zikopoulos, K, et al. Ruptured hemangioma of the umbilical cord and intrauterine fetal death, with review data. Pathol Res Pract. 2006;202:537–40.10.1016/j.prp.2006.02.008CrossRef Google Scholar PubMed

Daniel-Spiegel, E, Weiner, E, Gimburg, G, et al. The association of umbilical cord hemangioma with fetal vascular birthmarks. Prenat Diagn. 2005;25:300–3.10.1002/pd.1109CrossRef Google Scholar PubMed

References

Frank, HG, Malekzadeh, F, Kertschanska, S, et al. Immunohistochemistry of two different types of placental fibrinoid. Acta anatomica 1994;150:55–68.10.1159/000147602CrossRef Google Scholar PubMed

Vernof, KK, Benirschke, K, Kephart, GM, Wasmoen, TL, Gleich, GJ. Maternal floor infarction: relationship to X cells, major basic protein, and adverse perinatal outcome. Am J Obstet Gynecol 1992;167:1355–63.10.1016/S0002-9378(11)91716-5CrossRef Google Scholar

Benirschke, K, Driscoll, SG. Maternal Floor Infarction. In: Benirschke, K, Driscoll, SG, eds. Pathology of the Human Placenta. New York: Springer-Verlag; 1967:328–30.10.1007/978-1-4612-9809-0CrossRef Google Scholar

Naeye, RL. Maternal floor infarction. Hum Pathol 1985;16:823–8.10.1016/S0046-8177(85)80254-9CrossRef Google Scholar PubMed

Katzman, PJ, Genest, DR. Maternal floor infarction and massive perivillous fibrin deposition: histological definitions, association with intrauterine fetal growth restriction, and risk of recurrence. Pediatr Dev Pathol 2002;5:159–64.10.1007/s10024001-0195-yCrossRef Google Scholar PubMed

Faye-Petersen, OM, Ernst, LM. Maternal Floor Infarction and Massive Perivillous Fibrin Deposition. Surgical pathology clinics 2013;6:101–14.10.1016/j.path.2012.10.002CrossRef Google Scholar PubMed

Fox, H, Sebire, N. Pathology of the Placenta. 3 ed: Saunders Elsevier; 2007.Google Scholar

Andres, RL, Kuyper, W, Resnik, R, Piacquadio, KM, Benirschke, K. The association of maternal floor infarction of the placenta with adverse perinatal outcome. Am J Obstet Gynecol 1990;163:935–8.10.1016/0002-9378(90)91100-QCrossRef Google Scholar PubMed

Redline, RW, Jiang, JG, Shah, D. Discordancy for maternal floor infarction in dizygotic twin placentas. Hum Pathol 2003;34:822–4.10.1016/S0046-8177(03)00288-0CrossRef Google Scholar PubMed

Waters, BL, Ashikaga, T. Significance of perivillous fibrin/oid deposition in uterine evacuation specimens. Am J Surg Pathol 2006;30:760–5.10.1097/00000478-200606000-00014CrossRef Google Scholar PubMed

Gogia, N, Machin, GA. Maternal thrombophilias are associated with specific placental lesions. Pediatr Dev Pathol 2008;11:424–9.10.2350/07-09-0345.1CrossRef Google Scholar PubMed

Griffin, AC, Strauss, AW, Bennett, MJ, Ernst, LM. Mutations in long-chain 3-hydroxyacyl coenzyme a dehydrogenase are associated with placental maternal floor infarction/massive perivillous fibrin deposition. Pediatr Dev Pathol 2012;15:368–74.10.2350/12-05-1198-OA.1CrossRef Google Scholar PubMed

Mayhew, TM, Brotherton, L, Holliday, E, Orme, G, Bush, PG. Fibrin-type fibrinoid in placentae from pregnancies associated with maternal smoking: association with villous trophoblast and impact on intervillous porosity. Placenta 2003;24:501–9.10.1053/plac.2002.0943CrossRef Google Scholar PubMed

Uxa, R, Baczyk, D, Kingdom, JC, Viero, S, Casper, R, Keating, S. Genetic polymorphisms in the fibrinolytic system of placentas with massive perivillous fibrin deposition. Placenta 2010;31:499–505.10.1016/j.placenta.2010.03.013CrossRef Google Scholar PubMed

Linn, RL, Kiley, J, Minturn, L, et al. Recurrent massive perivillous fibrin deposition in the placenta associated with fetal renal tubular dysgenesis: case report and literature review. Pediatr Dev Pathol 2013;16:378–86.10.2350/13-06-1351-CR.1CrossRef Google Scholar PubMed

Taweevisit, M, Thorner, PS. Maternal floor infarction associated with oligohydramnios and cystic renal dysplasia: report of 2 cases. Pediatr Dev Pathol 2010;13:116–20.10.2350/09-06-0669-CR.1CrossRef Google Scholar PubMed

Mandsager, NT, Bendon, R, Mostello, D, Rosenn, B, Miodovnik, M, Siddiqi, TA. Maternal floor infarction of the placenta: prenatal diagnosis and clinical significance. Obstet Gynecol 1994;83:750–4.Google Scholar PubMed

Taweevisit, M, Thorner, PS. Maternal Floor Infarction/Massive Perivillous Fibrin Deposition Associated with Hypercoiling of a Single-Artery Umbilical Cord: A Case Report. Pediatr Dev Pathol 2016;19:69–73.10.2350/15-07-1673-CR.1CrossRef Google Scholar PubMed

Batcup, G, Holt, P, Hambling, MH, Gerlis, LM, Glass, MR. Placental and fetal pathology in Coxsackie virus A9 infection: a case report. Histopathology 1985;9:1227–35.CrossRef Google Scholar PubMed

Heller, D, Tellier, R, Pabbaraju, K, et al. Placental Massive Perivillous Fibrinoid Deposition associated with Coxsackievirus A16-report of a case, and review of the literature. Pediatr Dev Pathol. 2016;19:421–3.10.2350/15-10-1726-CR.1CrossRef Google Scholar PubMed

Salafia, CM, Cowchock, FS. Placental pathology and antiphospholipid antibodies: a descriptive study. Am J Perinatol 1997;14:435–41.10.1055/s-2007-994176CrossRef Google Scholar PubMed

Sebire, NJ, Backos, M, Goldin, RD, Regan, L. Placental massive perivillous fibrin deposition associated with antiphospholipid antibody syndrome. BJOG 2002;109:570–3.10.1111/j.1471-0528.2002.00077.xCrossRef Google Scholar PubMed

Redline, RW. Thrombophilia and placental pathology. Clin Obstet Gynecol 2006;49:885–94.10.1097/01.grf.0000211957.68745.6bCrossRef Google Scholar PubMed

Roberts, D, Schwartz, RS. Clotting and hemorrhage in the placenta–a delicate balance. N Engl J Med 2002;347:57–9.10.1056/NEJMe020061CrossRef Google Scholar PubMed

Rakheja, D, Bennett, MJ, Rogers, BB. Long-chain L-3-hydroxyacyl-coenzyme a dehydrogenase deficiency: a molecular and biochemical review. Lab Invest 2002;82:815–24.10.1097/01.LAB.0000021175.50201.46CrossRef Google Scholar PubMed

Whitten, AE, Romero, R, Korzeniewski, SJ, et al. Evidence of an imbalance of angiogenic/antiangiogenic factors in massive perivillous fibrin deposition (maternal floor infarction): a placental lesion associated with recurrent miscarriage and fetal death. Am J Obstet Gynecol 2013;208:310 e1–e11.10.1016/j.ajog.2013.01.017CrossRef Google Scholar PubMed

Romero, R, Whitten, A, Korzeniewski, SJ, et al. Maternal floor infarction/massive perivillous fibrin deposition: a manifestation of maternal antifetal rejection? Am J Reprod Immunol 2013;70:285–98.10.1111/aji.12143CrossRef Google Scholar PubMed

Hung, NA, Jackson, C, Nicholson, M, Highton, J. Pregnancy-related polymyositis and massive perivillous fibrin deposition in the placenta: are they pathogenetically related? Arthritis and rheumatism 2006;55:154–6.10.1002/art.21710CrossRef Google Scholar PubMed

Bendon, RW, Hommel, AB. Maternal floor infarction in autoimmune disease: two cases. Pediatr Pathol Lab Med 1996;16:293–7.10.1080/15513819609169291CrossRef Google Scholar PubMed

Redline, R. Maternal floor infarction and massive perivillous fibrin deposition: clinicopathological entities in flux. Adv Anat Pathol 2002;9:372–3.10.1097/00125480-200211000-00010CrossRef Google Scholar

Adams-Chapman, I, Vaucher, YE, Bejar, RF, Benirschke, K, Baergen, RN, Moore, TR. Maternal floor infarction of the placenta: association with central nervous system injury and adverse neurodevelopmental outcome. J Perinatol 2002;22:236–41.10.1038/sj.jp.7210685CrossRef Google Scholar PubMed

Heerema-McKenney, A, Popek, EJ, De Paepe, ME. Diagnostic Pathology: Placenta. Philadelphia, PA: Elsevier; 2015.Google Scholar

Katz, VL, Bowes, WA Jr., Sierkh, AE. Maternal floor infarction of the placenta associated with elevated second trimester serum alpha-fetoprotein. Am J Perinatol 1987;4:225–8.10.1055/s-2007-999778CrossRef Google Scholar PubMed

Chaiworapongsa, T, Romero, R, Korzeniewski, SJ, et al. Pravastatin to prevent recurrent fetal death in massive perivillous fibrin deposition of the placenta (MPFD). J Matern Fetal Neonatal Med 2016;29:855–62.10.3109/14767058.2015.1022864CrossRef Google Scholar PubMed

Al-Sahan, N, Grynspan, D, von Dadelszen, P, Gruslin, A. Maternal floor infarction: management of an underrecognized pathology. J Obstet Gynaecol Res 2014;40:293–6.10.1111/jog.12159CrossRef Google Scholar PubMed

Redline, RW, Patterson, P. Patterns of placental injury. Correlations with gestational age, placental weight, and clinical diagnoses. Arch Pathol Lab Med 1994;118:698–701.Google Scholar PubMed

Fox, H. Perivillous fibrin deposition in the human placenta. Am J Obstet Gynecol 1967;98:245–51.10.1016/S0002-9378(16)34594-XCrossRef Google Scholar PubMed

Pereira, L, Petitt, M, Fong, A, et al. Intrauterine growth restriction caused by underlying congenital cytomegalovirus infection. J Infect Dis 2014;209:1573–84.10.1093/infdis/jiu019CrossRef Google Scholar PubMed

Eden, TW. A study of the human placenta, pysiological and pathological. Journal of pathology and bacteriology 1897;4:265–83.10.1002/path.1700040212CrossRef Google Scholar

Basnet, K, Bentley-Lewis, R, Wexler, DJ, Kilic, F, Roberts, DJ. The prevalence of intervillous thrombi is increased in placentas from pregnancies complicated by diabetes. Pediatr Dev Pathol. 2016;19:502–5.10.2350/15-11-1734-OA.1CrossRef Google Scholar PubMed

Demmler, GJ. Congenital cytomegalovirus infection and disease. Advances in pediatric infectious diseases 1996;11:135–62.Google Scholar PubMed

Pass, RF, Stagno, S, Myers, GJ, Alford, CA. Outcome of symptomatic congenital cytomegalovirus infection: results of long-term longitudinal follow-up. Pediatrics 1980;66:758–62.10.1542/peds.66.5.758CrossRef Google Scholar PubMed

References

Alanjari, A, Wright, E, Keating, S, Ryan, G, Kingdom, J. Prenatal diagnosis, clinical outcomes, and associated pathology in pregnancies complicated by massive subchorionic thrombohematoma (Breus’ mole). Prenat Diagn. 2013;33(10):973–8.10.1002/pd.4176CrossRef Google Scholar PubMed

Shanklin, DR, Scott, JS. Massive subchorial thrombohaematoma (Breus’ mole). Br J Obstet Gynaecol. 1975;82(6):476–87.10.1111/j.1471-0528.1975.tb00673.xCrossRef Google Scholar PubMed

Fung, TY, To, KF, Sahota, DS, Chan, LW, Leung, TY, Lau, TK. Massive subchorionic thrombohematoma: a series of 10 cases. Acta Obstet Gynecol Scand. 2010;89(10):1357–61.10.3109/00016349.2010.512656CrossRef Google Scholar PubMed

Breus, C: Das Tuberose Subchoriale Haematom der Decidua. Leipzig, Deuticke, 1892Google Scholar

Yamada, S, Marutani, T, Hisaoka, M, Tasaki, T, Nabeshima, A, Shiraishi, M, Sasaguri, Y. Pulmonary hypoplasia on preterm infant associated with diffuse chorioamniotic hemosiderosis caused by intrauterine hemorrhage due to massive subchorial hematoma: report of a neonatal autopsy case. Pathol Int. 2012;62(8):543–8.10.1111/j.1440-1827.2012.02834.xCrossRef Google Scholar PubMed

Thomas, D, Makhoul, J, Müller, C. Fetal growth retardation due to massive subchorionic thrombohematoma: report of two cases. J Ultrasound Med. 1992;11(5):245–7.10.7863/jum.1992.11.5.245CrossRef Google Scholar PubMed

Perrin, EVDK. Placenta as a reflection of fetal disease: A brief overview. In, Pathology of the Placenta. Perrin, E.V.D.K. ed. Churchill Livingstone, New York, 1984.Google Scholar

Kim, DT, Riddell, DC, Welch, JP, Scott, H, Fraser, RB, Wright, JR Jr. Association between Breus’ mole and partial hydatidiform mole: chance or can hydropic villi precipitate placental massive subchorionic thrombosis? Pediatr Pathol Mol Med. 2002;21(5):451–9.10.1080/pdp.21.5.451.459CrossRef Google Scholar PubMed

Heller, DS, Rush, D, Baergen, RN. Subchorionic hematoma associated with thrombophilia: report of three cases. Pediatr Dev Pathol. 2003;6(3):261–4.10.1007/s10024-002-0107-9CrossRef Google Scholar PubMed

Fisteag-Kiprono, L, Foster, K, McKenna, D, Baptista, M. Antenatal sonographic diagnosis of massive subchorionic hematoma: a case report. J Reprod Med. 2005;50(3):219–21.Google Scholar PubMed

Sepulveda, W, Aviles, G, Carstens, E, Corral, E, Perez, N. Prenatal diagnosis of solid placental masses: the value of color flow imaging. Ultrasound Obstet Gynecol. 2000;16(6):554–8.10.1046/j.1469-0705.2000.00245.xCrossRef Google Scholar PubMed

Kojima, K, Suzuki, Y, Makino, A, Murakami, I, Suzumori, K. A case of massive subchorionic thrombohematoma diagnosed by ultrasonography and magnetic resonance imaging. Fetal Diagn Ther. 2001;16(1):57–60.10.1159/000053882CrossRef Google Scholar PubMed

Gupta, R, Sharma, R, Jain, T, Vashisht, S. Antenatal MRI diagnosis of massive subchorionic hematoma: a case report. Fetal Diagn Ther. 2007;22(6):405–8.10.1159/000106343CrossRef Google Scholar PubMed

Windrim, C, Athaide, G, Gerster, T, Kingdom, JC. Sonographic findings and clinical outcomes in women with massive subchorionic hematoma detected in the second trimester. J Obstet Gynaecol Can. 2011;33(5):475–910.1016/S1701-2163(16)34881-2CrossRef Google Scholar PubMed

Tuuli, MG, Norman, SM, Odibo, AO, Macones, GA, Cahill, AG. Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis. Obstet Gynecol. 2011;117(5):1205–12.10.1097/AOG.0b013e31821568deCrossRef Google Scholar PubMed

Wright, JR, Samson, KA, Cooper-Rosen, E, Riddel, DC. Breus’ Mole: DNA Shows Massive Subchorionic Hematoma is Maternal in Origin. Fetal Pediatr Pathol 1998;18:151–156.10.3109/15513819809168783CrossRef Google Scholar

Porat, S, Fitzgerald, B, Wright, E, Keating, S, Kingdom, JC. Placental hyperinflation and the risk of adverse perinatal outcome. Ultrasound Obstet Gynecol. 2013;42(3):315–21.10.1002/uog.12386CrossRef Google Scholar PubMed

Tancrède, S, Bujold, E, Giguère, Y, Renald, MH, Girouard, J, Forest, JC. Mid-trimester maternal serum AFP and hCG as markers of preterm and term adverse pregnancy outcomes. J Obstet Gynaecol Can. 2015;37(2):111–6.10.1016/S1701-2163(15)30331-5CrossRef Google Scholar PubMed

Toal, M, Chaddha, V, Windrim, R, Kingdom, J. Ultrasound detection of placental insufficiency in women with elevated second trimester serum alpha-fetoprotein or human chorionic gonadotropin. J Obstet Gynaecol Can. 2008;30(3):198–206.10.1016/S1701-2163(16)32756-6CrossRef Google Scholar PubMed

Kaplan, CG. Fetal Membranes and Surface. In: Color Atlas of Gross Placental Pathology. 2nd ed. New York, Springer, 2016.Google Scholar

Faye-Petersen, OM, Heller, DS, Joshi, VV. Chapter 8: Gross abnormalities of the placenta: lesions due to disturbances of maternal and of fetal blood flow. In: Handbook of Placental Pathology. Abingdon, Oxon: Taylor and Francis, 2006.Google Scholar

Fitzgerald, B, Shannon, P, Kingdom, J, Keating, S. Rounded intraplacental haematomas due to decidual vasculopathy have a distinctive morphology. J Clin Pathol. 2011;64(8):729–32.10.1136/jcp.2010.087916CrossRef Google Scholar PubMed

Neville, G, Russell, N, O’Donoghue, K, Fitzgerald, B. Rounded Intraplacental Haematomas – a high risk placental lesion as illustrated by a prospective study of 26 consecutive cases. Presentation, Society for Pediatic Pathology Spring Meeting; 2017;San Antonio, USA.Google Scholar

Aurioles-Garibay, A, Hernandez-Andrade, E, Romero, R, Qureshi, F, Ahn, H, Jacques, SM, Garcia, M, Yeo, L, Hassan, SS. Prenatal diagnosis of a placental infarction hematoma associated with fetal growth restriction, preeclampsia and fetal death: clinicopathological correlation. Fetal Diagn Ther. 2014;36(2):154–61.10.1159/000357841CrossRef Google Scholar PubMed

Bendon, RW. Nosology: infarction hematoma, a placental infarction encasing a hematoma. Hum Pathol. 2012;43(5):761–3.10.1016/j.humpath.2011.07.023CrossRef Google Scholar PubMed

Fitzgerald, B, Shannon, P, Kingdom, J, Keating, S. Basal plate plaque: a novel organising placental thrombotic process. J Clin Pathol. 2011;64(8):725–8.10.1136/jcp.2010.086355CrossRef Google Scholar PubMed

References

Hiersch, L, Krispin, E, Linder, N, et al. Meconium-stained amniotic fluid and neonatal morbidity in low-risk pregnancies at term: The effect of gestational age. Am J Perinatol. 2017;34(2):183–90.Google Scholar PubMed

Sheiner, E, Hadar, A, Shoham-Vardi, et al. The effect of meconium on perinatal outcome: a prospective analysis. J Matern Fetal Neonatal Med. 2002;11(1):54–9.10.1080/jmf.11.1.54.59CrossRef Google Scholar PubMed

Brabbing-Goldstein, D, Nir, D, Cohen, D, et al. Preterm meconium-stained amniotic fluid is an ominous sign for the development of chorioamnionitis and for in utero cord compression. J Matern Fetal Neonatal Med. 2017;8:1–4.Google Scholar

Ziadeh, SM, Sunna, E. Obstetric and perinatal outcome of pregnancies with term labour and meconium-stained amniotic fluid. Arch Gynecol Obstet. 2000;264(2):84–7.10.1007/s004040000088CrossRef Google Scholar PubMed

Ciftçi, AO, Tanyel, FC, Karnak, I, et al. In-utero defecation: fact or fiction? Eur J Pediatr Surg. 1999;9(6):376–80.CrossRef Google Scholar PubMed

Kimble, RM, Trudenger, B, Cass, D. Fetal defaecation: is it a normal physiological process? J Paediatr Child Health. 1999;35(2):116–9.10.1046/j.1440-1754.1999.00314.xCrossRef Google Scholar PubMed

Ahanya, SN, Lakshmanan, J, Morgan, BL, et al. Meconium passage in utero: mechanisms, consequences, and management. Obstet Gynecol Surv. 2005;60(1):45–56.10.1097/01.ogx.0000149659.89530.c2CrossRef Google Scholar PubMed

Lakshmanan, J, Ross, MG. Mechanism(s) of in utero meconium passage. J Perinatol. 2008;28 Suppl 3:S8–13.10.1038/jp.2008.144CrossRef Google Scholar PubMed

Frey, HA, Tuuli, MG, Shanks, AL, et al. Interpreting category II fetal heart rate tracings: does meconium matter? Am J Obstet Gynecol. 2014;211(6):644.e1–8.10.1016/j.ajog.2014.06.033CrossRef Google Scholar PubMed

Xu, H, Mas-Calvet, M, Wei, SQ, et al. Abnormal fetal heart rate tracing patterns in patients with thick meconium staining of the amniotic fluid: association with perinatal outcomes. Am J Obstet Gynecol. 2009;200(3):283.e1–7.10.1016/j.ajog.2008.08.043CrossRef Google Scholar PubMed

Vidyasagar, D, Zagariya, A. Studies of meconium-induced lung injury: inflammatory cytokine expression and apoptosis. J Perinatol. 2008;28 Suppl 3:S102–7.10.1038/jp.2008.153CrossRef Google Scholar PubMed

de Beaufort, AJ, Pelikan, DM, Elferink, JG, et al. Effect of interleukin 8 in meconium on in-vitro neutrophil chemotaxis. Lancet. 1998;352(9122):102–5.10.1016/S0140-6736(98)85013-7CrossRef Google Scholar PubMed

Yamada, T, Minakami, H, Matsubara, S, et al. Meconium-stained amniotic fluid exhibits chemotactic activity for polymorphonuclear leukocytes in vitro. J Reprod Immunol. 2000;46(1):21–30.10.1016/S0165-0378(99)00048-0CrossRef Google Scholar PubMed

Castellheim, A, Lindenskov, PH, Pharo, A, et al. Meconium is a potent activator of complement in human serum and in piglets. Pediatr Res. 2004;55(2):310–8.10.1203/01.PDR.0000100902.76021.8ECrossRef Google Scholar

Holcberg, G, Huleihal, M, Katz, M, et al. Vasoconstrictive activity of meconium stained amniotic fluid in the human placental vasculature. Eur J Obstet Gynecol Reprod Biol. 1999;87(2):147–50.10.1016/S0301-2115(99)00099-8CrossRef Google Scholar PubMed

King, EL, Redline, RW, Smith, SD, et al. Myocytes of chorionic vessels from placentas with meconium-associated vascular necrosis exhibit apoptotic markers. Hum Pathol. 2004;35(4):412–7.10.1016/j.humpath.2003.12.002CrossRef Google Scholar PubMed

Miller, PW, Coen, RW, Benirschke, K: Dating the time interval from meconium passage to birth. Obstet Gynecol. 1985;66:459–462.Google Scholar PubMed

Kovalak, EE, Dede, FS, Gelisen, O, et al. Nonreassuring fetal heart rate patterns and nucleated red blood cells in term neonates. Arch Gynecol Obstet. 2011;283(5):1005–9.10.1007/s00404-010-1517-yCrossRef Google Scholar PubMed

Beebe, LA, Cowan, LD, Altshuler, G. The epidemiology of placental features: associations with gestational age and neonatal outcome. Obstet Gynecol. 1996;87(5 Pt 1):771–8.10.1016/0029-7844(95)00483-1CrossRef Google Scholar PubMed

Kaspar, HG, Abu-Musa, A, Hannoun, A, et al. The placenta in meconium staining: lesions and early neonatal outcome. Clin Exp Obstet Gynecol. 2000;27(1):63–6.Google Scholar PubMed

Redline, RW, O’Riordan, MA. Placental lesions associated with cerebral palsy and neurologic impairment following term birth. Arch Pathol Lab Med. 2000;124(12):1785–91.10.5858/2000-124-1785-PLAWCPCrossRef Google Scholar PubMed

Chang, KT, Keating, S, Costa, S, et al: Third-trimester stillbirths: correlative neuropathology and placental pathology. Pediatr Dev Pathol. 2011;14(5):345–52.10.2350/10-07-0882-OA.1CrossRef Google Scholar PubMed

Martinez-Biarge, M, Cheong, JL, Diez-Sebastian, J, et al. Risk factors for neonatal arterial ischemic stroke: The importance of the intrapartum period. J Pediatr. 2016;173:62–68.10.1016/j.jpeds.2016.02.064CrossRef Google Scholar PubMed

Cimic, A, Baergen, RN. Meconium-associated umbilical vascular myonecrosis: correlations with adverse outcome and placental pathology. Pediatr Dev Pathol. 2016;19(4):315–319.10.2350/15-06-1660-OA.1CrossRef Google Scholar PubMed

Redline, RW. Severe fetal placental vascular lesions in term infants with neurologic impairment. Am J Obstet Gynecol. 2005;192(2):452–7.10.1016/j.ajog.2004.07.030CrossRef Google Scholar PubMed

References

Dulay, AT, Buhimschi, IA, Zhao, G, et al. Nucleated red blood cells are a direct response to mediators of inflammation in newborns with early-onset neonatal sepsis. Am J Obstet Gynecol. 2008;198(6):728.10.1016/j.ajog.2008.01.040CrossRef Google Scholar PubMed

Bedrick, AD. Nucleated red blood cells and fetal hypoxia: a biologic marker whose ‘timing’ has come? J Perinatol. 2014;34(2):85–6.10.1038/jp.2013.169CrossRef Google Scholar PubMed

Ferber, A, Minior, VK, Bornstein, E, et al: Fetal “non-reassuring status” is associated with elevation of nucleated red blood cell counts and interleukin-6. Am J Obstet Gynecol. 2005;192(5):1427–29.10.1016/j.ajog.2004.12.076CrossRef Google Scholar

Stachon, A, Bolulu, O, Holland-Letz, T, et al. Association between nucleated red blood cells in blood and the levels of erythropoietin, interleukin 3, interleukin 6, and interleukin 12p70. Shock. 2005;24(1):34–9.10.1097/01.shk.0000164693.11649.91CrossRef Google Scholar PubMed

Şaracoglu, F, Sahin, I, Eser, E, et al: Nucleated red blood cells as a marker in acute and chronic fetal asphyxia. Int J Gynaecol Obstet. 2000;71(2):113–8.10.1016/S0020-7292(00)00259-9CrossRef Google Scholar PubMed

Hanlon-Lundberg, KM, Kirby, RS: Nucleated red blood cells as a marker of acidemia in term neonates. Am J Obstet Gynecol. 1999;181(1):196–201.10.1016/S0002-9378(99)70459-XCrossRef Google Scholar PubMed

Madazli, R, Tuten, A, Calay, Z, et al: The incidence of placental abnormalities, maternal and cord plasma malondialdehyde and vascular endothelial growth factor levels in women with gestational diabetes mellitus and nondiabetic controls. Gynecol Obstet Invest. 2008;65(4):227–32.10.1159/000113045CrossRef Google Scholar PubMed

Teramo, K, Klemetti, M, Tikkanen, M, et al. Maternal diabetes and fetal hypoxia [article in Finnish]. Duodecim. 2013;129(3):228–34.Google Scholar PubMed

Escobar, J, Teramo, K, Stefanovic, V, et al. Amniotic fluid oxidative and nitrosative stress biomarkers correlate with fetal chronic hypoxia in diabetic pregnancies. Neonatology. 2013;103(3):193–8.10.1159/000345194CrossRef Google Scholar PubMed

Cetin, H, Yalaz, M, Akisu, M, et al. Polycythaemia in infants of diabetic mothers: β-hydroxybutyrate stimulates erythropoietic activity. J Int Med Res. 2011;39(3):815–21.10.1177/147323001103900314CrossRef Google Scholar PubMed

Widness, JA, Teramo, KA, Clemons, GK, et al. Temporal response of immunoreactive erythropoietin to acute hypoxemia in fetal sheep. Pediatr Res. 1986;20(1):15–9.10.1203/00006450-198601000-00004CrossRef Google Scholar PubMed

Blackwell, SC, Hallak, M, Hotra, JW, et al. Timing of fetal nucleated red blood cell count elevation in response to acute hypoxia. Biol Neonate. 2004;85:217–20.10.1159/000075808CrossRef Google Scholar PubMed

D’Souza, SW, Black, P, MacFarlane, T, et al. Hametologic values in cord blood in relation to fetal hypoxia. Br J Obstet Gynaecol. 1981;88:129–32.Google Scholar PubMed

Şaracoglu, F, Sahin, I, Eser, E, et al. Nucleated red blood cells as a marker in acute and chronic fetal asphyxia. Int J Gynaecol Obstet. 2000;71(2):113–8.10.1016/S0020-7292(00)00259-9CrossRef Google Scholar PubMed

Klausen, T, Olsen, NV, Poulsen, TD, et al. Hypoxemia increases serum interleukin-6 in humans. Eur J Appl Physiol. 1997;76:480–2.10.1007/s004210050278CrossRef Google Scholar PubMed

Naldini, A, Carraro, F, Silvestri, S, et al. Hypoxia affects cytokine production and proliferative responses by human peripheral mononuclear cells. J Cell Physiol. 1997;173:335–42.10.1002/(SICI)1097-4652(199712)173:3<335::AID-JCP5>3.0.CO;2-O3.0.CO;2-O>CrossRef Google Scholar PubMed

von Lindern, M, Zauner, W, Mellitzer, G, et al. The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro. Blood. 1999;94(2):550–9.10.1182/blood.V94.2.550CrossRef Google Scholar PubMed

Falchi, M, Varricchio, L, Martelli, F, et al. Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion. Haematologica. 2015;100(2):178–87.10.3324/haematol.2014.114405CrossRef Google Scholar PubMed

Lewis, JM, Hori, TS, Rise, ML, et al. Transcriptome responses to heat stress in the nucleated red blood cells of the rainbow trout (Oncorhynchus mykiss). Physiol Genomics. 2010;42(3):361–73.10.1152/physiolgenomics.00067.2010CrossRef Google Scholar

Lim, SK, Park, SH. High glucose stimulates the expression of erythropoietin in rat glomerular epithelial cells. Lab Anim Res. 2011;27(3):245–50.10.5625/lar.2011.27.3.245CrossRef Google Scholar PubMed

Ferber, A, Grassi, A, Akyol, D, et al. The association of fetal heart rate patterns with nucleated red blood cell counts at birth. Am J Obstet Gynecol. 2003;188(5):1228–30.10.1067/mob.2003.352CrossRef Google Scholar PubMed

Phelan, JP, Kirkendall, C, Korst, LM, et al. Nucleated red blood cell and platelet counts in asphyxiated neonates sufficient to result in permanent neurologic impairment. J Matern Fetal Neonatal Med. 2007;20(5):377–80.10.1080/14767050701232596CrossRef Google Scholar PubMed

Goel, M, Dwivedi, R, Gohiya, P, Hedge, D. Nucleated red blood cell in cord blood as a marker of perinatal asphyxia. J Clin Neonatol. 2013;2(4):179–82.10.4103/2249-4847.123097CrossRef Google Scholar PubMed

Boskabadi, H, Zakerihamidi, M, Sadeghian, MH, et al. Nucleated red blood cells count as a prognostic biomarker in predicting the complications of asphyxia in neonates. J Matern Fetal Neonatal Med. 2017;(21):2551–56.10.1080/14767058.2016.1256988CrossRef Google Scholar

Redline, RW: Elevated circulating fetal nucleated red blood cells and placental pathology in term infants who develop cerebral palsy. Hum Pathol. 2008;39(9):1378–1384.10.1016/j.humpath.2008.01.017CrossRef Google Scholar PubMed

Walsh, BH, Boylan, GB, Dempsey, EM, et al. Association of nucleated red blood cells and severity of encephalopathy in normothermic and hypothermic infants. Acta Paediatr. 2013;102(2):e64–7.10.1111/apa.12086CrossRef Google Scholar PubMed

Bergman, RA, Afifi, AK, Heidger, JR, PM, eds. Digital anatomy atlas, Atlas of microscopic anatomy; Section 4: Blood. In: Atlas of hematologic neoplasms, 1st ed, 2009, Springer NY, Sun T, 11–16.Google Scholar

Axt-Fliedner, R, Hendrik, HJ, Schmidt, W. Nucleated red blood cell counts in growth-restricted neonates with absent or reversed-end-diastolic umbilical artery velocity. Clin Exp Obstet Gynecol. 2002;29(4):242–6.Google Scholar PubMed

Baschat, AA, Gungor, S,Kush, ML, et al. Nucleated red blood cell counts in the first week of life: a critical appraisal of relationships with perinatal outcome in preterm growth-restricted neonates. Am J Obstet Gynecol. 2007;197(3):286,e 1–8.10.1016/j.ajog.2007.06.020CrossRef Google Scholar PubMed

Ghosh, B, Mittal, S, Kumar, S, Dadhwal, V. Prediction of perinatal asphyxia with nucleated red blood cells in cord blood of newborns. Int J Gynaecol Obstet. 2003;81(3):267–71.10.1016/S0020-7292(03)00124-3CrossRef Google Scholar PubMed

Hebbar, S, Misha, M, Rai, L. Significance of maternal and cord blood nucleated red blood cell count in pregnancies complicated by preeclampsia. J Pregnancy. 2014;2014:496416.10.1155/2014/496416CrossRef Google Scholar PubMed

Li, J, Kobata, K, Kamei, Y, et al. Nucleated red blood cell counts: an early predictor of brain injury and 2-year outcome in neonates with hypoxic-ischemic encephalopathy in the era of cooling-based treatment. Brain Dev. 2014; 36(6):472–8.10.1016/j.braindev.2013.06.012CrossRef Google Scholar

Buonocore, G, Perrone, S, Gioia, D, et al. Nucleated red blood cell count at birth as an index of perinatal brain damage. Am J Obstet Gynecol. 1999;181(6):1500–5.10.1016/S0002-9378(99)70396-0CrossRef Google Scholar

Korst, LM, Phelan, JP, Ahn, MO, Martin, GI. Nucleated red blood cells: an update on the marker for fetal asphyxia. Am J Obstet Gynecol. 1996;175(4 Pt 1):843–6.10.1016/S0002-9378(96)80010-XCrossRef Google Scholar PubMed

Redline, RW, O’Riordan, MA. Placental lesions associated with cerebral palsy and neurologic impairment following term birth. Arch Pathol Lab Med. 2000;124:1785–91.10.5858/2000-124-1785-PLAWCPCrossRef Google Scholar PubMed

Bernson-Leung, ME, Boyd, TK, Meserve, EE, et al. Placental pathology in neonatal stroke: A retrospective case-control study. J Pediatr. Published: J Pediatr. 2018;195:39–47.Google Scholar

Christensen, RD, Henry, E, Andres, RL, Bennett, ST: Reference ranges for blood concentrations of nucleated red blood cells in neonates. Neonatology. 2011;99(4):289–94.10.1159/000320148CrossRef Google Scholar PubMed

Christensen, RD, Henry, E, Jopling, J, Wiedmeier, SE: The CBC: reference ranges for neonates. Semin Perinatol. 2009;33(1):3–11.10.1053/j.semperi.2008.10.010CrossRef Google Scholar PubMed

Rolfo, A, Maconi, M, Cardaropoli, S, et al. Nucleated red blood cells in term fetuses: reference values using an automated analyzer. Neonatology. 2007;92(3):205–8.10.1159/000102096CrossRef Google Scholar PubMed

Hanlon-Lundberg, KM, Kirby, RS, Gandhi, S, et al. Nucleated red blood cells in cord blood of singleton term neonates. Am J Obstet Gynecol. 1997;176(6):1149–54.10.1016/S0002-9378(97)70328-4CrossRef Google Scholar

Hermansen, MC. Nucleated red blood cells in the fetus and newborn. Arch Dis Child Fetal Neonatal Ed. 2001;84:F211–15.10.1136/fn.84.3.F211CrossRef Google Scholar PubMed

McCarthy, JM, Capullari, T, Thompson, Z, et al. Umbilical cord nucleated red blood cell counts: normal values and the effect of labor. J Perinatol. 2006;26(2):89–92.10.1038/sj.jp.7211437CrossRef Google Scholar PubMed

Perrone, S, Vezzosi, P, Longini, M, et al. Nucleated red blood cell count in term and preterm newborns: reference values at birth. Arch Dis Child Fetal Neonatal. 2005;90:F174–F175.10.1136/adc.2004.051326CrossRef Google Scholar PubMed

References

Opitz, JM, Johnson, DR, Gilbert-Barness, EF. ADAM “Sequence” part II: hypothesis and speculation. Am J Med Genet Part A 2015;167A:478–503.10.1002/ajmg.a.36937CrossRef Google Scholar PubMed

Higginbotham, MC, Jones, KL, Hall, BD, Smith, DW. The amnionic band disruption complex: timing of amniotic rupture and variable spectra of consequent defects. J Pediatr 1979;95:544–9.Google Scholar

Kalousek, D, Bamforth, S. Amnion rupture sequence in previable fetuses. Am J Med Genet 1988;31:63–73.10.1002/ajmg.1320310110CrossRef Google Scholar PubMed

Benirschke, K, Burton, GJ, Baergen, RN. Anatomy and Pathology of the Placental Membranes. In: Pathology of the Human Placenta. 6th ed. New York: Springer. 2012:287–94.10.1007/978-3-642-23941-0CrossRef Google Scholar

Orioli, IM, Ribeiro, MG, Castilla, EE. Clinical and epidemiological studies of amniotic deformity, adhesion and mutilation (ADAM) sequence in a South American (ECLAMC) population. Am J Med Genet 2003;118A:135–45.10.1002/ajmg.a.10194CrossRef Google Scholar

Torpin, A. Amniochorionic mesoblastic fibrous strings and aniotic bands. Associated constricting fetal malformations or fetal death. Am J Obstet Gynecol 1965;91:65–75.10.1016/0002-9378(65)90588-0CrossRef Google Scholar PubMed

Streeter, GL . Focal deficiencies in fetal tissues and their relation to intra-uterine amputation. Contrib Embryol 1930;22:3–44.Google Scholar

Van Allen, MI, Curry, C, Gallagher, L. Limb body wall complex: I. Pathogenesis. Am J Med Genet 1987;28:529–48.Google Scholar PubMed

Van Allen, MI, Curry, C, Walden, CE, Gallagher, L, Patten, RM. Limb body wall complex: II. Limb and spine defects. Am J Med Genet 1987;28:549–65.Google Scholar PubMed

Yang, SS. ADAM sequence and innocent amniotic band: manifestations of early amnion rupture. Am J Med Genet 1990;37:562–8.10.1002/ajmg.1320370429CrossRef Google Scholar PubMed

Yang, SS, Levine, AJ, Sanborn, JR, Delp, RA. Amniotic rupture, extra-amniotic pregnancy, and vernix granulomata. Am J Surg Path 1984;8:117–22.10.1097/00000478-198402000-00005CrossRef Google Scholar PubMed

Keswani, SG, Johnson, MP, Adzik, NS, Hori, S, Howell, LJ, Wilson, RD, Hedrick, H, Flake, AW, Crombleholme, TM. In utero limb salvage: fetoscopic release of amniotic bands for threatened limb amputation. J Pediatr Surg 2003;38:848–51.10.1016/S0022-3468(03)00109-XCrossRef Google Scholar PubMed

Soldado, F, Aguirre, M, Pierὀ, JL, Fontecha, CG, Esteves, M, Velez, R, Martinez-Ibáñez, V . Fetal surgery of extremity amniotic bands: an experimental model of in utero limb salvage in fetal lamb. J Pediatr Orthop 2009;29:98–102.10.1097/BPO.0b013e318192196eCrossRef Google Scholar PubMed

Lubinsky, M, Sujansky, E, Sanger, W, Salyards, W, Severn, C. Familial amniotic bands. Am J Med Genet 1983;14:81–7.10.1002/ajmg.1320140113CrossRef Google Scholar PubMed

Strauss, A, Hasbergen, U, Paek, B, Bauerfeind, I, Hepp, H. Intra-uterine fetal demise caused by amniotic band syndrome after standard amniocentesis. Fetal Diagn Ther 2000;15:4–7.10.1159/000020968CrossRef Google Scholar PubMed

Jacques, SM, Qureshi, F. Subamnionic vernix caseosa. Pediatr pathol 1994;14:585–93.10.3109/15513819409023333CrossRef Google Scholar PubMed

Bendon, RW, Ray, RB. The pathologic findings of the fetal membranes in very prolonged amniotic fluid leakage. Arch Pathol Lab Med 1986;110:47–50.Google Scholar PubMed

Landing, BH. Amnion nodosum: a lesion of the placenta apparently associated with deficient secretion of fetal urine. Am J Obstet Gynecol. 1950;60:1339–42.10.1016/0002-9378(50)90016-0CrossRef Google Scholar PubMed

Bartman, J, Driscoll, SG. Amnion nodosum and hypoplastic cystic kidneys: an electron microscopic and microdissection study. Obstet Gynecol. 1968;32:700–05.Google Scholar PubMed

Bain, AD, Beath, MM, Flint, WF. Sirenomelia and monomelia with renal agenesis and amnion nodosum. Arch Dis Child. 1960;35:250–3.10.1136/adc.35.181.250CrossRef Google Scholar PubMed

Adeniran, A J, Stanek, J. Amnion nodosum revisited. Clinicopathologic and placental correlations. Arch Pathol Lab Med. 2007;131:1829–33.10.5858/2007-131-1829-ANRCAPCrossRef Google Scholar PubMed

References

Potter, JF, Schoeneman, M. Metastasis of maternal cancer to the placenta and fetus. Cancer 1970;25:380–8.10.1002/1097-0142(197002)25:2<380::AID-CNCR2820250216>3.0.CO;2-Q3.0.CO;2-Q>CrossRef Google Scholar

Pavlidis, N, Pentheroudakis, G. Metastatic Involvement of Placenta and Foetus in Pregnant Women with Cancer. Cancer and Pregnancy. Berlin, Heidelberg: Springer Berlin Heidelberg; 2008:183–94.Google Scholar

Pavlidis, NA. Coexistence of pregnancy and malignancy. The oncologist 2002;7:279–87.10.1634/theoncologist.2002-0279CrossRef Google Scholar PubMed

Pentheroudakis, G, Pavlidis, N. Cancer and pregnancy: poena magna, not anymore. European journal of cancer 2006;42:126–40.10.1016/j.ejca.2005.10.014CrossRef Google Scholar

Fox, H, Sebire, N. Pathology of the Placenta. 3 ed: Saunders Elsevier; 2007.Google Scholar

Dildy, GA 3rd, Moise, KJ Jr., Carpenter, RJ Jr., Klima, T. Maternal malignancy metastatic to the products of conception: a review. Obstet Gynecol Surv 1989;44:535–40.10.1097/00006254-198907000-00008CrossRef Google Scholar

Rothman, LA, Cohen, CJ, Astarloa, J. Placental and fetal involvement by maternal malignancy: a report of rectal carcinoma and review of the literature. Am J Obstet Gynecol 1973;116:1023–34.10.1016/S0002-9378(16)33854-6CrossRef Google Scholar PubMed

Baergen, RN, Johnson, D, Moore, T, Benirschke, K. Maternal melanoma metastatic to the placenta: a case report and review of the literature. Arch Pathol Lab Med 1997;121:508–11.Google Scholar

Alexander, A, Samlowski, WE, Grossman, D, et al. Metastatic melanoma in pregnancy: risk of transplacental metastases in the infant. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21:2179–86.10.1200/JCO.2003.12.149CrossRef Google Scholar PubMed

Shuhaila, A, Rohaizak, M, Phang, KS, Mahdy, ZA. Maternal melanoma with placental metastasis. Singapore medical journal 2008;49:e71–2.Google Scholar PubMed

Valenzano Menada, M, Moioli, M, Garaventa, A, et al. Spontaneous regression of transplacental metastases from maternal melanoma in a newborn: case report and review of the literature. Melanoma research 2010;20:443–9.10.1097/CMR.0b013e32833faf6aCrossRef Google Scholar

Cavell, B. Transplacental Metastasis of Malignant Melanoma. Report of a Case. Acta paediatrica Supplementum 1963:SUPPL146:37–40.10.1111/j.1651-2227.1963.tb05515.xCrossRef Google Scholar PubMed

Cavell, B. Letter: Transplacental melanoma–one-year survival. Pediatrics 1976;57:978–9.10.1542/peds.57.6.978CrossRef Google Scholar PubMed

Anderson, JF, Kent, S, Machin, GA. Maternal malignant melanoma with placental metastasis: a case report with literature review. Pediatr Pathol 1989;9:35–42.10.3109/15513818909022330CrossRef Google Scholar PubMed

Dillman, RO, Vandermolen, LA, Barth, NM, Bransford, KJ. Malignant melanoma and pregnancy ten questions. The Western journal of medicine 1996;164:156–61.Google Scholar PubMed

Surbone, A, Pecatori, F, Pavlidis, N. Cancer and Pregnancy. Berlin: Springer; 2008.10.1007/978-3-540-71274-9CrossRef Google Scholar PubMed

Sheikh, SS, Khalifa, MA, Marley, EF, Bagg, A, Lage, JM. Acute monocytic leukemia (FAB M5) involving the placenta associated with delivery of a healthy infant: case report and discussion. Int J Gynecol Pathol 1996;15:363–6.10.1097/00004347-199610000-00010CrossRef Google Scholar

Osada, S, Horibe, K, Oiwa, K, et al. A case of infantile acute monocytic leukemia caused by vertical transmission of the mother’s leukemic cells. Cancer 1990;65:1146–9.10.1002/1097-0142(19900301)65:5<1146::AID-CNCR2820650519>3.0.CO;2-J3.0.CO;2-J>CrossRef Google Scholar PubMed

Catlin, EA, Roberts, JD Jr., Erana, R, et al. Transplacental transmission of natural-killer-cell lymphoma. N Engl J Med 1999;341:85–91.10.1056/NEJM199907083410204CrossRef Google Scholar PubMed

Maruko, K, Maeda, T, Kamitomo, M, Hatae, M, Sueyoshi, K. Transplacental transmission of maternal B-cell lymphoma. Am J Obstet Gynecol 2004;191:380–1.10.1016/j.ajog.2003.12.036CrossRef Google Scholar PubMed

Priesel, A, Winkelbauer, A. Placentare Ubertragung des lymphogranulomas. Virchows Arch 1926;262:749.10.1007/BF01996871CrossRef Google Scholar

Meguerian-Bedoyan, Z, Lamant, L, Hopfner, C, Pulford, K, Chittal, S, Delsol, G. Anaplastic large cell lymphoma of maternal origin involving the placenta: case report and literature survey. Am J Surg Pathol 1997;21:1236–41.10.1097/00000478-199710000-00016CrossRef Google Scholar PubMed

Vetter, G, Zimmermann, F, Bruder, E, Schulzke, S, Hosli, I, Vetter, M. Aggressive Breast Cancer during Pregnancy with a Rare Form of Metastasis in the Maternal Placenta. Geburtshilfe und Frauenheilkunde 2014;74:579–82.Google Scholar PubMed

Boussios, S, Han, SN, Fruscio, R, et al. Lung cancer in pregnancy: report of nine cases from an international collaborative study. Lung cancer 2013;82:499–505.10.1016/j.lungcan.2013.09.002CrossRef Google Scholar PubMed

Jackisch, C, Louwen, F, Schwenkhagen, A, et al. Lung cancer during pregnancy involving the products of conception and a review of the literature. Arch Gynecol Obstet 2003;268:69–77.10.1007/s00404-002-0356-xCrossRef Google Scholar

Thelmo, MC, Shen, EP, Shertukde, S. Metastatic pulmonary adenocarcinoma to placenta and pleural fluid: clinicopathologic findings. Fetal Pediatr Pathol 2010;29:45–56.10.3109/15513810903266625CrossRef Google Scholar PubMed

Tolar, J, Coad, JE, Neglia, JP. Transplacental transfer of small-cell carcinoma of the lung. N Engl J Med 2002;346:1501–2.10.1056/NEJM200205093461917CrossRef Google Scholar PubMed

Innamaa, A, Deering, P, Powell, MC. Advanced lung cancer presenting with a generalized seizure in pregnancy. Acta Obstet Gynecol Scand 2006;85:1148–9.10.1080/00016340600604062CrossRef Google Scholar PubMed

Walker, JW, Reinisch, JF, Monforte, HL. Maternal pulmonary adenocarcinoma metastatic to the fetus: first recorded case report and literature review. Pediatr Pathol Mol Med 2002;21:57–69.10.1080/pdp.21.1.57.69CrossRef Google Scholar

Cailliez, D, Moirot, MH, Fessard, C, Hemet, J, Philippe, E. [Placental localisation of cancer of the cervix (author’s transl)]. Journal de gynecologie, obstetrique et biologie de la reproduction 1980;9:461–3.Google Scholar PubMed

Can, NT, Robertson, P, Zaloudek, CJ, Gill, RM. Cervical squamous cell carcinoma metastatic to placenta. Int J Gynecol Pathol 2013;32:516–9.10.1097/PGP.0b013e3182763178CrossRef Google Scholar PubMed

Herskovic, E, Ryan, M, Weinstein, J, Wadhwani, NR. Maternal to fetal transmission of cervical carcinoma. Pediatric radiology 2014;44:1035–8.10.1007/s00247-013-2858-zCrossRef Google Scholar PubMed

Fritsch, M, Jaffe, ES, Griffin, C, Camacho, J, Raffeld, M, Kingma, DW. Lymphoproliferative disorder of fetal origin presenting as oligohydramnios. Am J Surg Pathol 1999;23:595–601.10.1097/00000478-199905000-00015CrossRef Google Scholar PubMed

Dai, Q, Reddy, VV, Choi, JK, Faye-Petersen, OM. Trisomy 21-associated transient abnormal myelopoiesis involving the maternal space of the placenta: a case report and literature review. Pediatr Dev Pathol 2014;17:366–73.10.2350/14-04-1476-CR.1CrossRef Google Scholar PubMed

Kume, A, Morikawa, T, Ogawa, M, Yamashita, A, Yamaguchi, S, Fukayama, M. Congenital neuroblastoma with placental involvement. International journal of clinical and experimental pathology 2014;7:8198–204.Google Scholar PubMed

de Tar, MW, Dittman, W, Gilbert, J. Transient myeloproliferative disease of the newborn: case report with placental, cytogenetic, and flow cytometric findings. Hum Pathol 2000;31:396–8.Google Scholar PubMed

Ohyama, M, Ijiri, R, Tanaka, Y, et al. Congenital primitive epithelial tumor of the liver showing focal rhabdoid features, placental involvement, and clinical features mimicking multifocal hemangioma or stage 4S neuroblastoma. Hum Pathol 2000;31:259–63.CrossRef Google Scholar PubMed

Perkins, DG, Kopp, CM, Haust, MD. Placental infiltration in congenital neuroblastoma: a case study with ultrastructure. Histopathology 1980;4:383–9.Google Scholar PubMed

Reif, P, Hofer, N, Kolovetsiou-Kreiner, V, Benedicic, C, Ratschek, M. Metastasis of an undifferentiated fetal soft tissue sarcoma to the maternal compartment of the placenta: maternal aspects, pathology findings and review of the literature on fetal malignancies with placenta metastases. Histopathology 2014;65:933–42.10.1111/his.12442CrossRef Google Scholar

O’Day, MP, Nielsen, P, al-Bozom, I, Wilkins, IA. Orbital rhabdomyosarcoma metastatic to the placenta. Am J Obstet Gynecol 1994;171:1382–3.Google Scholar PubMed

Nath, ME, Kanbour, A, Hu, J, Surti, U, Kunschner, A, Dickman, PS. Transplantation of congenital primitive neuroectodermal tumor of fetus to the uterus of mother: application of biotin-labeled chromosome-specific probes. Int J Gynecol Cancer 1995;5:459–64.10.1046/j.1525-1438.1995.05060459.xCrossRef Google Scholar

de Tar, M, Sanford Biggerstaff, J. Congenital renal rhabdoid tumor with placental metastases: immunohistochemistry, cytogenetic, and ultrastructural findings. Pediatr Dev Pathol 2006;9:161–7.CrossRef Google Scholar PubMed

White, FV, Dehner, LP, Belchis, DA, et al. Congenital disseminated malignant rhabdoid tumor: a distinct clinicopathologic entity demonstrating abnormalities of chromosome 22q11. Am J Surg Pathol 1999;23:249–56.CrossRef Google Scholar PubMed

Schneiderman, H, Wu, AY, Campbell, WA, et al. Congenital melanoma with multiple prenatal metastases. Cancer 1987;60:1371–7.10.1002/1097-0142(19870915)60:6<1371::AID-CNCR2820600635>3.0.CO;2-03.0.CO;2-0>CrossRef Google Scholar PubMed

Robinson, HB Jr., Bolande, RP. Case 3. Fetal hepatoblastoma with placental metastases. Pediatr Pathol 1985;4:163–7.10.3109/15513818509025915CrossRef Google Scholar PubMed

Doss, BJ, Vicari, J, Jacques, SM, Qureshi, F. Placental involvement in congenital hepatoblastoma. Pediatr Dev Pathol 1998;1:538–42.10.1007/s100249900074CrossRef Google Scholar PubMed

Gray, ES, Balch, NJ, Kohler, H, Thompson, WD, Simpson, JG. Congenital leukaemia: an unusual cause of stillbirth. Arch Dis Child 1986;61:1001–6.10.1136/adc.61.10.1001CrossRef Google Scholar PubMed

Las Heras, J, Leal, G, Haust, MD. Congenital leukemia with placental involvement. Report of a case with ultrastructural study. Cancer 1986;58:2278–81.Google Scholar PubMed

Allan, RR, Wadsworth, LD, Kalousek, DK, Massing, BG. Congenital erythroleukemia: a case report with morphological, immunophenotypic, and cytogenetic findings. American journal of hematology 1989;31:114–21.10.1002/ajh.2830310208CrossRef Google Scholar PubMed

Mora, J, Dobrenis, AM, Bussel, JB, Aledo, A. Spontaneous remission of congenital acute nonlymphoblastic leukemia with normal karyotype in twins. Medical and pediatric oncology 2000;35:110–3.10.1002/1096-911X(200008)35:2<110::AID-MPO4>3.0.CO;2-Z3.0.CO;2-Z>CrossRef Google Scholar PubMed

Heald, B, Hilden, JM, Zbuk, K, et al. Severe TMD/AMKL with GATA1 mutation in a stillborn fetus with Down syndrome. Nature clinical practice Oncology 2007;4:433–8.10.1038/ncponc0876CrossRef Google Scholar

Roy, A, Roberts, I, Vyas, P. Biology and management of transient abnormal myelopoiesis (TAM) in children with Down syndrome. Semin Fetal Neonatal Med 2012;17:196–201.10.1016/j.siny.2012.02.010CrossRef Google Scholar PubMed

Ravishankar, S, Hoffman, L, Lertsburapa, T, Welch, J, Treaba, D, De Paepe, ME. Extensive placental choriovascular infiltration by maturing myeloid cells in down syndrome-associated transient abnormal myelopoiesis. Pediatr Dev Pathol 2015;18:231–6.CrossRef Google Scholar PubMed

Bombery, M, Vergilio, JA. Transient abnormal myelopoiesis in neonates: GATA get the diagnosis. Arch Pathol Lab Med 2014;138:1302–6.10.5858/arpa.2014-0304-CCCrossRef Google Scholar PubMed

Allen, AT, Dress, AF, Moore, WF. Mirror syndrome resulting from metastatic congenital neuroblastoma. Int J Gynecol Pathol 2007;26:310–2.10.1097/pgp.0b013e31802e3bfeCrossRef Google Scholar PubMed

Scalvenzi, M, Palmisano, F, Cacciapuoti, S, et al. Giant congenital melanocytic naevus with proliferative nodules mimicking congenital malignant melanoma: a case report and review of the literature of congenital melanoma. Case reports in dermatological medicine 2013;2013:473635.10.1155/2013/473635CrossRef Google Scholar PubMed

Viana, AC, Gontijo, B, Bittencourt, FV. Giant congenital melanocytic nevus. Anais brasileiros de dermatologia 2013;88:863–78.10.1590/abd1806-4841.20132233CrossRef Google Scholar PubMed

Alper, J, Holmes, LB, Mihm, MC Jr. Birthmarks with serious medical significance: nevocullular nevi, sebaceous nevi, and multiple cafe au lait spots. J Pediatr 1979;95:696–700.10.1016/S0022-3476(79)80713-1CrossRef Google Scholar PubMed

Castilla, EE, da Graca Dutra, M, Orioli-Parreiras, IM. Epidemiology of congenital pigmented naevi: I. Incidence rates and relative frequencies. The British journal of dermatology 1981;104:307–15.Google Scholar PubMed

Demian, SD, Donnelly, WH, Frias, JL, Monif, GR. Placental lesions in congenital giant pigmented nevi. Am J Clin Pathol 1974;61:438–42.10.1093/ajcp/61.3.438CrossRef Google Scholar PubMed

Holaday, WJ, Castrow, FF 2nd. Placental metastasis from a fetal giant pigmented nevus. Archives of dermatology 1968;98:486–8.10.1001/archderm.1968.01610170046007CrossRef Google Scholar PubMed

Sotelo-Avila, C, Graham, M, Hanby, DE, Rudolph, AJ. Nevus cell aggregates in the placenta. A histochemical and electron microscopic study. Am J Clin Pathol 1988;89:395–400.10.1093/ajcp/89.3.395CrossRef Google Scholar PubMed

Antaya, RJ, Keller, RA, Wilkerson, JA. Placental nevus cells associated with giant congenital pigmented nevi. Pediatric dermatology 1995;12:260–2.10.1111/j.1525-1470.1995.tb00173.xCrossRef Google Scholar PubMed

Jauniaux, E, de Meeus, MC, Verellen, G, Lachapelle, JM, Hustin, J. Giant congenital melanocytic nevus with placental involvement: long-term follow-up of a case and review of the literature. Pediatr Pathol 1993;13:717–21.10.3109/15513819309048258CrossRef Google Scholar PubMed

Kinsler, V, Thomas, A, Ishida, M, et al. Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 62 of NRAS. The Journal of investigative dermatology 2013;133:2229–36.10.1038/jid.2013.70CrossRef Google Scholar

Charbel, C, Fontaine, RH, Malouf, GG, et al. NRAS mutation is the sole recurrent somatic mutation in large congenital melanocytic nevi. The Journal of investigative dermatology 2014;134:1067–74.10.1038/jid.2013.429CrossRef Google Scholar

Etchevers, HC. Hiding in plain sight: molecular genetics applied to giant congenital melanocytic nevi. The Journal of investigative dermatology 2014;134:879–82.10.1038/jid.2013.531CrossRef Google Scholar PubMed

Zaal, LH, Mooi, WJ, Klip, H, van der Horst, CM. Risk of malignant transformation of congenital melanocytic nevi: a retrospective nationwide study from The Netherlands. Plastic and reconstructive surgery 2005;116:1902–9.10.1097/01.prs.0000189205.85968.12CrossRef Google Scholar PubMed

Bittencourt, FV, Marghoob, AA, Kopf, AW, Koenig, KL, Bart, RS. Large congenital melanocytic nevi and the risk for development of malignant melanoma and neurocutaneous melanocytosis. Pediatrics 2000;106:736–41.10.1542/peds.106.4.736CrossRef Google Scholar PubMed

References

Jacques, SM, Qureshi, F. Adrenocortical and hepatic nodules within placental tissue. Pediatr Dev Pathol 2003;6:464–6.Google Scholar PubMed

Khalifa, MA, Gersell, DJ, Hansen, CH, Lage, JM. Hepatic (hepatocellular) adenoma of the placenta: a study of four cases. Int J Gynecol Pathol 1998;17:241–4.10.1097/00004347-199807000-00008CrossRef Google Scholar PubMed

Vesoulis, Z, Agamanolis, D. Benign hepatocellular tumor of the placenta. Am J Surg Pathol 1998;22:436–40.10.1097/00000478-199803000-00011CrossRef Google Scholar PubMed

DeNapoli, TS. Coexistent chorangioma and hepatic adenoma in one twin placenta: a case report and review of the literature. Pediatr Dev Pathol 2015;18:422–5.10.2350/14-12-1592-CR.1CrossRef Google Scholar PubMed

Chen, KTK, Chan, KM, Kassel, SH. Hepatocellular adenoma of the placenta. Am J Surg Pathol 1986;10:436–40.10.1097/00000478-198606000-00009CrossRef Google Scholar PubMed

Cox, JN, Chavrier, F. Heterotopic adrenocortical tissue within a placenta. Placenta 1980;1:131–3.10.1016/S0143-4004(80)80021-XCrossRef Google Scholar PubMed

Labarrere, CA, Caccamo, D, Telenta, M, Althabe, O, Gutman, R. A nodule of adrenocortical tissue within a human placenta: light microscopic and immunocytochemical findings. Placenta 1984;5:139–43.10.1016/S0143-4004(84)80057-0CrossRef Google Scholar PubMed

Qureshi, F, Jacques, SM. Adrenocortical heterotopia in the placenta. Pediatr Pathol Lab Med 1995;15:51–6.10.3109/15513819509026939CrossRef Google Scholar PubMed

Guschmann, M, Vogel, M, Urban, M. Adrenal tissue in the placenta: a heterotopia caused by migration and embolism? Placenta 2000;21:427–31.10.1053/plac.1999.0497CrossRef Google Scholar PubMed

Zhong, H, Xu, B, Popiolek, DA. Growth patterns of placental and paraovarian adrenocortical heterotopias are different. Case Rep Pathol 2013: 205692.10.1155/2013/205692CrossRef Google Scholar

Unger, JL, Placental teratoma Am J Clin Pathol 1989;92:371–3.10.1093/ajcp/92.3.371CrossRef Google Scholar PubMed

Block, D, Cruikshank, S, Kelly, K, Stanely, M. Placental teratoma. Int J Gynecol Obstet 1991;34:377–80.10.1016/0020-7292(91)90608-8CrossRef Google Scholar PubMed

Meinhard, K, Dimitrov, S, Nicolov, A, Dimitrova, V, Vassilev, N. Placental teratoma – a case report. Pathol Res Pract 1999;195:649–51.10.1016/S0344-0338(99)80130-7CrossRef Google Scholar PubMed

Fox, H, Butler-Manuel, R. A teratoma of the placenta. J Pathol Bacteriol 1964;88:137–40.10.1002/path.1700880118CrossRef Google Scholar PubMed

Stephens, TD, Spall, R, Urfer, AG, Martin, R. Fetus amorphus or placental teratoma? Teratology 1989;40: 1–10.CrossRef Google Scholar PubMed

Fox, H. Pathology of the Placenta. Philadelphia: WB Saunders, 1978:343–67.Google Scholar PubMed

Drut, R, Mortera, M, Drut, RM. Yolk sac tumor of the placenta in Wiedemann-Beckwith Syndrome. Pediatr Dev Pathol 1998;1:534–7.10.1007/s100249900073CrossRef Google Scholar PubMed

Matsuyama, T, Kushima, M, Yamochi-Onizuka, T, Ota, H. Placental yolk sac tumor with divergent endodermal differentiation. Int J Gynecol Pathol 2004;23;398–402.10.1097/01.pgp.0000139662.05916.70CrossRef Google Scholar PubMed

References

Lake, BD, Young, EP, Winchester, BG. Prenatal diagnosis of lysosomal storage diseases. Brain Pathol. 1998;8:133–49.10.1111/j.1750-3639.1998.tb00141.xCrossRef Google Scholar PubMed

Platt, FM, Boland, B, van der Spoel, AC. The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction. J Cell Biol. 2012;199:723–34.10.1083/jcb.201208152CrossRef Google Scholar PubMed

Whybra, C, Mengel, E, Russo, A, et al. Lysosomal storage disorder in non-immunological hydrops fetalis (NIHF): more common than assumed? Report of four cases with transient NIHF and a review of the literature. Orphanet J Rare Dis. 2012;7:86.CrossRef Google Scholar

Case Records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23–1997. A premature newborn infant with congenital ascites. N Engl J Med. 1997;337:260–7.Google Scholar

Cox, P. Syndromes with stippled epiphyses/chondrodysplasia punctata (London medical database). Pediatric pathologists of the world, listserv. July 17, 2011.Google Scholar

Redline, RW, Zaragoza, MV, Hassold, T. Prevalence of developmental and inflammatory lesions in non-molar first trimester spontaneous abortions. Hum Pathol. 1999;30:93–100.10.1016/S0046-8177(99)90307-6CrossRef Google Scholar

Stanek, J, Bove, KE. Pediatric Pathology Forum. http://pedpathdiscoursehostingnet/t/interesting-lipid-storage-case/450. 2016.Google Scholar

Dainese, L, Adam, N, Boudjemaa, S, et al. Glycogen Storage Disease Type IV and Early Implantation Defect: Early Trophoblastic Involvement Associated with a New GBE1 Mutation. Pediatr Dev Pathol. 2016;19:512–5.CrossRef Google Scholar PubMed

Grafe, MR, Benirschke, K. Ultrastructural study of the amniotic epithelium in a case of gastroschisis. Pediatr Pathol. 1990;10:95–101.10.3109/15513819009067099CrossRef Google Scholar

Fowler, DJ, Anderson, G, Vellodi, A, et al. Electron microscopy of chorionic villus samples for prenatal diagnosis of lysosomal storage disorders. Ultrastruct Pathol. 2007;31:15–21.10.1080/01913120601169469CrossRef Google Scholar PubMed

Jones, CJ, Lendon, M, Chawner, LE, et al. Ultrastructure of the human placenta in metabolic storage disease. Placenta. 1990;11:395–411.10.1016/S0143-4004(05)80215-2CrossRef Google Scholar PubMed

Thurberg, BL, Politei, JM. Histologic abnormalities of placental tissues in Fabry disease: a case report and review of the literature. Hum Pathol. 2012;43:610–4.10.1016/j.humpath.2011.07.020CrossRef Google Scholar PubMed

Kostadinov, S, Shah, BA, Alroy, J, et al. A case of galactosialidosis with novel mutations of the protective protein/cathepsin a gene: diagnosis prompted by trophoblast vacuolization on placental examination. Pediatr Dev Pathol. 2014;17:474–7.10.2350/14-05-1500-CR.1CrossRef Google Scholar PubMed

Ferreira, CR, Gahl, WA. Lysosomal storage diseases. Translat Sci of Rare Dis. 2017;25:1–71.Google Scholar

Ernst, LM, Parkash, V. Placental pathology in fetal bartter syndrome. Pediatr Dev Pathol. 2002;5:76–9.10.1007/s10024-001-0092-4CrossRef Google Scholar PubMed

Maruyama, H, Shinno, Y, Fujiwara, K, et al. Nephrocalcinosis and placental findings in neonatal Bartter syndrome. AJP Rep. 2013;3:21–4.Google Scholar PubMed

Krasikov, NE, McKusick, VA. #241200 Bartter syndrome, type 2, antenatal; BARTS2. www.omim.org/entry/241200.Google Scholar

Dane, B, Dane, C, Aksoy, F, et al. Antenatal Bartter syndrome: analysis of two cases with placental findings. Fetal Pediatr Pathol. 2010;29:121–6.10.3109/15513811003777276CrossRef Google Scholar PubMed

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