Perinatal Neuropathology

Mirna Lechpammer; Marc Del Bigio; Rebecca Folkerth

doi:10.1017/9781316671863

There is an increasing demand for high-standard fetal and infant neuropathology examinations. Novel imaging techniques, development of new diagnostic methods and advances in genetics have stimulated the interest in gaining additional knowledge on developmental, perinatal and neonatal neuropathology. Approaching the subject from a practical standpoint, diagnostic templates for reports are provided in this essential guide to aid clinicians with different areas of expertise. Each chapter will includes numerous high-quality images, accompanied by explanatory legends from the authors' own experiences. Covering autopsy and tissue processing techniques, the authors discuss a range of disorders such as neural tube defects, brain tumours, storage disorders and many others. This book provides access to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover. Compiling the latest advances in fetal and infant diagnostics and care, this book is a highly valuable educational resource.

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Contents

Perinatal Neuropathology
pp i-ii
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Perinatal Neuropathology - Title page
pp iii-iii
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Copyright page
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Contents
pp v-viii
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Preface
pp ix-ix
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Acknowledgments
pp x-x
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Abbreviations
pp xi-xii
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Section I - Techniques and Practical Considerations
pp 1-80
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Approach to Autopsy of the Perinatal Nervous System
pp 1-12
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Chapter 1 - Clinical Considerations
pp 1-2
- By Rebecca Folkerth
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Chapter 2 - Imaging
pp 3-4
- By Rebecca Folkerth
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Chapter 3 - External Exam of the Fetus/Infant
pp 5-7
- By Rebecca Folkerth
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Chapter 4 - Autopsy and Research Consent
pp 8-12
- By Marc Del Bigio
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Ancillary Studies
pp 13-44
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Chapter 5 - Microbiology
pp 13-24
- By Mirna Lechpammer
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Chapter 6 - Cytogenetics and Molecular Diagnostics
pp 25-30
- By Mirna Lechpammer
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Chapter 7 - Metabolic Studies
pp 31-38
- By Mirna Lechpammer
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Chapter 8 - Toxicology
pp 39-44
- By Mirna Lechpammer
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Prosection Techniques
pp 45-58
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Chapter 9 - Brain Prosection
pp 45-49
- By Marc Del Bigio
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Chapter 10 - Spinal Cord Prosection
pp 50-52
- By Rebecca Folkerth
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Chapter 11 - Neuromuscular Specimens
pp 53-55
- By Mirna Lechpammer
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Chapter 12 - Eye Specimens
pp 56-58
- By Mirna Lechpammer
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Tissue Selection
pp 59-70
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Chapter 13 - Selection of Brain Areas for Microscopic Examination
pp 59-61
- By Mirna Lechpammer, Rebecca Folkerth
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Chapter 14 - Technical Considerations in Perinatal CNS Tissue Processing
pp 62-64
- By Mirna Lechpammer
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Chapter 15 - Staining Techniques
pp 65-70
- By Marc Del Bigio
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Reporting
pp 71-71
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Chapter 16 - Formulation of Diagnosis
pp 71-72
- By Rebecca Folkerth
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Chapter 17 - Reporting Templates
pp 73-78
- By Mirna Lechpammer
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