Published online by Cambridge University Press: 21 November 2024
Charcot–Marie Tooth (CMT) is the most common type of hereditary peripheral neuropathy known as hereditary motor and sensory neuropathy (HMSN). These individuals typically experience a gradual distal lower extremity weakness and sensory loss over years, which results in symmetric distal lower extremity atrophy, foot drop, hammertoes, and pes cavus foot deformities. Distal upper extremity weakness and numbness will often occur as the lower extremity symptoms progress up the knees.
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