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Published online by Cambridge University Press: 21 November 2024
First used in 1949, the term chronic traumatic encephalopathy (CTE) has been known by many names throughout medical history, including “punch drunk” in the 1920s, and dementia pugilistica coined in 1937 from the Latin work pugil meaning “boxer” or “fist.” The cause of CTE remains heavily debated and is thought to be due to a combination of progressive microanatomical changes caused by repetitive closed-head injuries including direct impact from sporting collisions or blast exposures from military experience. Recent research has also proposed a genetic predisposition.
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