This chapter considers literary expressions of sovereignty in the nineteenth-century United States that underscore sovereignty’s oppositional nature and its productive potential, and it demonstrates how these literary expressions were, like public argument about sovereignty, constructed through the interplay between law and religion. Religious discourse provided a set of terms, examples, and motifs that shaped the nineteenth-century debate over political autonomy as it ranged across matters of territorial possession and the individual conscience. I first briefly address ideas of sovereignty that circulated in the long nineteenth century and informed US literature and public argument. Then I turn to competing visions of sovereignty expressed by the Cherokee Nation, the state of Georgia, the US federal government, and the US Supreme Court in the early decades of the nineteenth century. In the final section, I briefly turn to the figure of John Brown who, in linking the vision of Indigenous sovereignty expressed by the Cherokee Nation to the sovereign individuality espoused by Henry David Thoreau and the Transcendentals, serves as a harbinger of the contests over political sovereignty that ultimately led to the US Civil War.