Reducing inequalities in preconception health and care is critical to improving the health and life chances of current and future generations. A hybrid workshop was held at the 2023 UK Preconception Early and Mid-Career Researchers (EMCR) Network conference to co-develop recommendations on ways to address inequalities in preconception health and care. The workshop engaged multi-disciplinary professionals across diverse career stages and people with lived experience (total n = 69). Interactive discussions explored barriers to achieving optimal preconception health, driving influences of inequalities and recommendations. The Socio-Ecological Model framed the identified themes, with recommendations structured at interpersonal (e.g. community engagement), institutional (e.g. integration of preconception care within existing services) and environmental/societal levels (e.g. education in schools). The co-developed recommendations provide a framework for addressing inequalities in preconception health, emphasising the importance of a whole-systems approach. Further research and evidence-based interventions are now needed to advance the advocacy and implementation of our recommendations.

Two preregistered web studies are presented that explore the impact of experience on the tendency to accept recommended defaults. In each of the 100 trials, participants (n = 180, n = 165) could accept a recommended default option or choose a less attractive prospect. The location of the options (left or right) was randomly determined before each trial. Both studies compared two conditions. Under Condition Dominant, the default option maximized participants’ payoff in all trials. Under Condition Protective, the default option protected the participants from rare losses and maximized expected return but decreased payoff in most trials. The results reveal a tendency to accept the default in Condition Dominant but the opposite tendency in Condition Protective. This pattern was predicted by assuming that in addition to promoting specific actions, the presentation of the default changes the set of feasible strategies, and choice between these strategies reflects reliance on small samples of past experiences.

One of the key responsibilities of public institutions in liberal democracies is to formulate recommendations for decision makers. However, public institutions realize that decision makers will often partly ignore their recommendations. This situation of “partial compliance” with recommendations raises a number of philosophical issues for institutions. Based on an analysis of 570 recommendations drawn from 40 Quebec public-sector documents and reports, we identify two issues surrounding the structure of public-policy recommendations.

The International Psychogeriatric Association (IPA) has expressed significant concerns over the use of physical restraints in older people across diverse aged care settings. Following an extensive analysis of the available literature, the IPA’s Early Career Network (ECN) has formulated a collection of evidence-based recommendations aimed at guiding the use of physical restraints within various care contexts and demographic groups. Physical restraints not only infringe upon human rights but also raise significant safety concerns that adversely impact the physical, psychological, social, and functional well-being of older adults. Furthermore, their effectiveness in geriatric settings remains inadequate. Given these considerations, the IPA and its ECN firmly assert that the use of physical restraints should only be considered as a final recourse in the care of older people.

Academic and community investigators conducting community-engaged research (CEnR) are often met with challenges when seeking Institutional Review Board (IRB) approval. This scoping review aims to identify challenges and recommendations for CEnR investigators and community partners working with IRBs. Peer-reviewed articles that reported on CEnR, specified study-related challenges, and lessons learned for working with IRBs and conducted in the United States were included for review. Fifteen studies met the criteria and were extracted for this review. Four challenges identified (1) Community partners not being recognized as research partners (2) Cultural competence, language of consent forms, and literacy level of partners; (3) IRBs apply formulaic approaches to CEnR; & (4) Extensive delays in IRB preparation and approval potentially stifle the relationships with community partners. Recommendations included (1) Training IRBs to understand CEnR principles to streamline and increase the flexibility of the IRB review process; (2) Identifying influential community stakeholders who can provide support for the study; and (3) Disseminating human subjects research training that is accessible to all community investigator to satisfy IRB concerns. Findings from our study suggest that IRBs can benefit from more training in CEnR requirements and methodologies

Early research on farmed mink was predominantly concerned with increased productivity; however, in recent years there have been an increasing number of studies related to welfare. The biology of feral mink has also become better understood, and such knowledge can aid in the assessment of welfare on farms, or in the interpretation of problems related to captivity. This paper is a comprehensive review of research pertinent to the welfare of farmed American mink, Mustela vison, in relation to their housing and management. It indicates how housing conditions might be changed to improve welfare, and where our present knowledge is insufficient. Many significant aspects of mink behaviour in the wild, such as their lack of social contact, their tendency to travel long distances and use several den sites, and regular swimming and diving, are denied them in captivity. Farmed mink also show high levels of stereotypy, suggesting that their welfare is not good. Welfare may be improved by appropriate environmental enrichment and changes in the social environment of farmed mink. In general, studies aimed at improving housing conditions have been limited in scope and outlook.

In the UK, numerous pedigree dogs of many breeds experience compromised welfare due to the direct and indirect effects of selective breeding. Many breeds are selected to have physical conformations which, although perceived by some to be desirable, have direct negative effects upon their welfare. Dogs are regularly bred whose heads are too large and pelvises too small to birth naturally or whose faces are so flat that they are unable to breathe or exercise normally. There are also many indirect effects of selective breeding for appearance, including significantly elevated prevalence of specific diseases within particular breeds. Current breeding practices can therefore result in unnecessary suffering due to pain, disability, disease and behavioural problems. In this paper, we summarise and review the current scientific evidence for such suffering, and difficulties associated with assessing the impact of current breeding practices. Limited record-keeping, lack of transparency in the breeding and showing world, and the absence of sufficient research, mean that the full extent of the problem is difficult to assess. Furthermore, the collection of data is currently unsystematic, and although there are specific case studies of individual breeds and particular disorders, relatively few have been conducted in the UK. Individual breeds each suffer from their own array of problems, so each breed's survival and improvement (in terms of health and welfare) is likely to require a different specific course of action. With 209 breeds currently registered in the UK, this makes the situation complex. We collate and present a range of suggestions which may help to improve pedigree dog welfare significantly, and prioritise these based on expert opinion.

The Clinical and Translational Science Award (CTSA) Program recognizes that advancing diversity, equity, inclusion, and accessibility (DEIA) requires moving beyond statements of commitment to transformative actions. In 2021, the CTSA Program created a Task Force (TF) to initiate work in support of structural and transformational initiatives that advance DEIA for the consortium and its individual hubs. We describe the process of forming the expertise-driven (DEIA) TF and our activities to date. We 1) developed and adopted the DEIA Learning Systems Framework to guide our approach; 2) defined a set of recommendations across four focus areas (Institutional; Programmatic; Community-Centered; and Social, Cultural, Environmental); and 3) designed and disseminated a survey to capture the CTSA Program’s baseline demographic, community, infrastructural, and leadership diversity. The CTSA Consortium also elevated the TF to a standing Committee to extend our understanding, development, and implementation of DEIA approaches to translational and clinical science. These initial steps provide a foundation for collectively fostering environment that support DEIA across the research continuum.

As COVID-19 becomes endemic, identifying vulnerable population groups for severe infection outcomes and defining rapid and effective preventive and therapeutic strategies remains a public health priority. We performed an umbrella review, including comprehensive studies (meta-analyses and systematic reviews) investigating COVID-19 risk for infection, hospitalization, intensive care unit (ICU) admission, and mortality in people with psychiatric disorders, and outlined evidence- and consensus-based recommendations for overcoming potential barriers that psychiatric patients may experience in preventing and managing COVID-19, and defining optimal therapeutic options and current research priorities in psychiatry. We searched Web of Science, PubMed, and Ovid/PsycINFO databases up to 17 January 2022 for the umbrella review. We synthesized evidence, extracting when available pooled odd ratio estimates for the categories “any mental disorder” and “severe mental disorders.” The quality of each study was assessed using the AMSTAR-2 approach and ranking evidence quality. We identified four systematic review/meta-analysis combinations, one meta-analysis, and three systematic reviews, each including up to 28 original studies. Although we rated the quality of studies from moderate to low and the evidence ranged from highly suggestive to non-significant, we found consistent evidence that people with mental illness are at increased risk of COVID-19 infection, hospitalization, and most importantly mortality, but not of ICU admission. The risk and the burden of COVID-19 in people with mental disorders, in particular those with severe mental illness, can no longer be ignored but demands urgent targeted and persistent action. Twenty-two recommendations are proposed to facilitate this process.

Hobby metal detectorists search for archaeological finds as individuals and within groups, the latter being the focus of this article. Such groups come together as “clubs” and “meetings,” but also as part of large, often commercially run events typically known as “rallies.” All these activities are attractive to detectorists because they provide them with access to land to search, along with the promise of making interesting (even valuable) discoveries, and they have a social dimension. They are common in England and also well established in several countries in northwest Europe, partly due to changing legislation. Although policies and mechanisms are often in place for collaboration with individual detectorists and even local metal-detecting clubs, larger events (not least, the large-scale commercial rallies increasingly occurring in England) present challenges for professional archaeologists, specifically in relation to the capacity to properly record finds and manage potential damage to the historic environment. To respond appropriately to these changes, a greater understanding of detectorists’ events is needed. For this reason, we explore and define the scale, nature, and diversity of group events, relating them to different legislative and cultural contexts in Flanders (Belgium), England (and Wales), and Finland. Subsequently, we outline challenges associated with group events and identify possible ways forward.

Indigenous people face numerous challenges to their mental health across the world. We consider the situation in Bangladesh, where those living in the remote hill tracts areas of Eastern Bangladesh experience widespread difficulties. Few seek attention for their problems from professional services, in part because of stigma or a lack of awareness that help could be made available, but also because in these remote areas few resources are available. We make recommendations to improve this situation, which could be implemented with the assistance of primary healthcare services and traditional healers.