As governments prepare for the decisive round of negotiations for the global plastics treaty in August 2025, trade remains a largely overlooked yet indispensable element in shaping an effective and equitable agreement. We argue that trade, spanning plastic feedstocks, resins, products, and waste, forms the connective tissue of the plastics economy and that it must be embedded in the treaty’s architecture. Drawing on global trade data, country cases, and precedent from multilateral environmental agreements, we demonstrate how trade both drives plastic pollution and can serve as a lever for circularity and sustainability. We outline the asymmetries in global plastics trade and their implications for equity and implementation, especially for small and import-dependent states. The article proposes a suite of actionable recommendations for INC-5.2, including trade-related transparency, WTO-aligned treaty provisions, and dedicated capacity-building support. By integrating trade governance into the plastics treaty, negotiators can build an agreement that is both environmentally ambitious and structurally sound.