Although the energy stored in the lean tissue (LT) and adipose tissue (AT) is well known, the energy required to synthesise these tissues is obscure. Theoretically, the energy at the point at which ΔLT/Δ body weight (BW) reaches 100 % on a regression line, which indicates the relationship between ΔLT/ΔBW and the energy required for BW gain, is considered to be the energy expended to synthesise LT. Therefore, we investigated this relationship in rats. Rats were fed diets with different ratios of protein, fat and carbohydrates because their ΔLT/ΔBW values were expected to be different. Six-week-old male Sprague-Dawley rats had ad libitum access to normal (N, n 6), high-fat (HF, n 7) or high-protein (HP, n 8) diets for 4 weeks. The ΔLT/ΔBW was 0·77 in the N, 0·70 in the HF and 0·87 in the HP groups, respectively. The average energy required to gain BW was 8·8 kJ/g in the N group, 7·0 kJ/g in the HF group and 11·3 kJ/g in the HP group. We observed a positive correlation between ΔLT/ΔBW and energy required for BW gain. The regression line demonstrated that the energy expended to synthesise LT was 13·9 kJ/g and AT was −7·9 kJ/g. Therefore, combined with the energy stored in LT, the energy required to accumulate LT is approximately 19 kJ/g, whereas the energy to accumulate AT could not be elucidated.

La question de facteurs psychologiques et ou psychiatriques favorisant l’apparition d’état de dépendance est au cœur de la pratique addictologique. Ces facteurs de risques potentiels ou ces comorbidités influencent de manière significative la pratique des soins et la prévention. Trouble de l’humeur et de l’attention sont probablement les troubles psychiatriques les plus liés aux conduites additives soulevant des facteurs communs à leurs expressions. L’usage du tabac constitue un facteur général de vulnérabilité aux additions et aux troubles psychiatriques. En retour, l’addictologie au travers de certains de ces paradigmes tels la prévention des risques et des dommages interroge le soin psychiatrique.

This note provides a correct proof of the result claimed by the second author that locally compact normal spaces are collectionwise Hausdorff in certain models obtained by forcing with a coherent Souslin tree. A novel feature of the proof is the use of saturation of the non-stationary ideal on ${{\omega }_{1}}$, as well as of a strong form of Chang's Conjecture. Together with other improvements, this enables the consistent characterization of locally compact hereditarily paracompact spaces as those locally compact, hereditarily normal spaces that do not include a copy of ${{\omega }_{1}}$.

Extending the work of Larson and Todorcevic, we show that there is a model of set theory in which normal spaces are collectionwise Hausdorff if they are either first countable or locally compact, and yet there are no first countable $L$-spaces or compact $S$-spaces. The model is one of the form $\text{PFA}\left( S \right)\left[ S \right]$, where $S$ is a coherent Souslin tree.

If T ∈ L(X) is such that T′ is a scalar-type prespectral operator, then Re T′ and Im T′ are both dual operators. It is shown that that the possession of a functional calculus for the continuous functions on the spectrum of T is equivalent to T′ being scalar-type prespectral of class X, thus answering a question of Berkson and Gillespie.

Recent studies have reported cognitive asymmetries in patients with Alzheimer's disease (AD) and in individuals with apolipoprotein E ε4 (APOE ε4) genotype who are in the preclinical phase of AD. This increased frequency of cognitive asymmetry, typically defined as a significant discrepancy (in either direction) between verbal and spatial abilities, often occurs despite an absence of differences on traditional measures of central tendency (i.e., mean test scores). We prospectively studied the relationship between APOE genotype and two modality-specific executive-function tasks: The Verbal Fluency and Design Fluency tests of the Delis-Kaplan Executive Function System (D-KEFS) in 52 normal functioning older adult participants who were grouped according to the presence (n = 24) or absence (n = 28) of the APOE ε4 allele. Nondemented older adults with the APOE ε4 allele demonstrated a greater frequency of cognitive asymmetric profile on the new switching conditions of the Verbal and Design Fluency measures than the APOE non-ε4 individuals. This study further supports the utility of assessing cognitive asymmetry for the detection of subtle cognitive differences in individuals at-risk for AD, and suggests that dual-task executive function tests (i.e., fluency plus switching) may serve as a useful preclinical marker of AD. (JINS, 2005, 11, 863–870.)

We establish generalizations for normal selfmaps of complex spaces of the Schwarz lemma and of recent results on convergence of iterates of holomorphic selfmaps of taut spaces.

Consider the convex hull of n independent, identically distributed points in the plane. Functionals of interest are the number of vertices Nn, the perimeter Ln and the area An of the convex hull. We study the asymptotic behaviour of these three quantities when the points are standard normally distributed. In particular, we derive the variances of Nn, Ln and An for large n and prove a central limit theorem for each of these random variables. We enlarge on a method developed by Groeneboom (1988) for uniformly distributed points supported on a bounded planar region. The process of vertices of the convex hull is of central importance. Poisson approximation and martingale techniques are used.

Some theorems on the existence of continuous real-valued functions on a topological space (for example, insertion, extension, and separation theorems) can be proved without involving uncountable unions of open sets. In particular, it is shown that well-known characterizations of normality (for example the Katětov-Tong insertion theorem, the Tietze extension theorem, Urysohn's lemma) are characterizations of normal σ-rings. Likewise, similar theorems about extremally disconnected spaces are true for σ-rings of a certain type. This σ-ring approach leads to general results on the existence of functions of class α.

A space has the shrinking property if, for every open cover {Va | a ∈ A}, there is an open cover {Wa | a ∈ A} with for each a ∈ A.lt is strangely difficult to find an example of a normal space without the shrinking property. It is proved here that any ∑-product of metric spaces has the shrinking property.

Independent observations X0, X1…, XN+1 are drawn from each of N populations whose distribution functions F(x – θi) have means θ i, 0 ≦ i < N, and we wish to calculate the probability Pk;N that X0 is the k th largest observation. For normal populations an approximation is given for PK;N based on a Taylor series expansion in the θ 's. If F(x) has an increasing failure rate, as is the case for the normal, an upper bound can be given for the ‘win' probability P1;N Some moment relations for normal order statistics are also given.