Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • Chapter 1 - Anatomical and Physiological Issues Affecting Anaesthesia in Neonates and Young Children

  • Edited by James Ip, Great Ormond Street Hospital for Children, London, Grant Stuart, Great Ormond Street Hospital for Children, London, Isabeau Walker, Great Ormond Street Hospital for Children, London, Ian James, Great Ormond Street Hospital for Children, London
  • Book:
    Core Topics in Paediatric Anaesthesia
    Published online:
    06 February 2025
    Print publication:
    13 February 2025, pp 1-12

  • Summary

    The neonatal period marks the transition from prenatal to postnatal life. This transition is characterised by rapid physiological change and neurodevelopmental plasticity. Anaesthesia, surgery and perioperative events have the potential to trigger long-lasting adverse outcomes. Understanding the changes that occur in the neonatal period is the key to delivering safe and effective care. In this chapter, we consider the development of major organ systems in utero, the transition from intrauterine to extrauterine life and aspects of newborn physiology relevant to the paediatric anaesthetist. We will also address the continuing debate regarding the potential for anaesthesia exposure in infancy to lead to persistent neurocognitive impairment.