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1 results

  • Chapter 22 - Osteoarthritic Knee Pain

  • from Part V - Extremities
  • Edited by Omar Viswanath, Creighton University, Omaha, Ivan Urits, Southcoast Brain & Spine Center, Wareham
  • Book:
    Cambridge Handbook of Pain Medicine
    Published online:
    01 December 2023
    Print publication:
    14 December 2023, pp 173-180

  • Summary

    Osteoarthritis is a common etiology of chronic knee pain and disability associated with aging, weight, and physical inactivity. Global radiographic evidence of knee OA is present in 28.7% of people over 40 years old.Global symptomatic evidence of knee OA is present in 12.4% of people over 40 years old. “Wear and tear” damage to hip joint leading to dysfunctional ECM reorganization leads to chronic onset of pain that is worse with use and associated with decreased knee mobility. Years of conservative treatment with exercise, weight loss, and oral anti-inflammatories can mitigate the disease progression, but severe cases may require intraarticular injections or knee arthroplasty. Some promising injections hope to better manage chronic symptoms by reversing the course of the disease; however, knee arthroplasty remains a gold standard treatment of severe knee OA.