This chapter discusses the relation of global extractivisms to global deforestation, making novel claims about the role of forests in the international system. This is a global, world-ecological analysis of why forests seem to have not mattered in the interstate system and how they are still overlooked in favor of a free flow of commodity trade and interstate competition. The impacts of the world system on forests are explored over the past 5,000 years, focusing especially on the past 550 years. “Epochal moments,” for example, wars or events like the COVID-19 pandemic, are particularly detrimental to retaining the world’s old-growth forests. One should avoid overgeneralizations of how global capitalism or humanity (as the “Anthropocene”) drive deforestation. Thus, the chapter utilizes a long-term, world-system perspective, focusing on how the current structures of the world-system drive deforestation. The chapter uncovers how the nature of the interstate system affects the efforts by global environmental governance and other means to try to curb or control deforestation. This curbing is fundamentally restricted by the lobbying and political power of RDPEs.