Recently, Donoso, Le, Moreira, and Sun studied the asymptotic behaviour of the averages of completely multiplicative functions over the Gaussian integers. They derived Wirsing’s theorem for Gaussian integers, answered a question of Frantzikinakis and Host for the sum of two squares, and obtained a variant of a theorem of Bergelson and Richter on ergodic averages along the number of prime factors of integers. In this paper, we will show the analogue of these results for co-prime integer pairs. Moreover, building on Frantzikinakis and Host’s results, we obtain some convergences on the multilinear averages of multiplicative functions over primitive lattice points.