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4 results

  • Tongue–lip adhesion and tongue repositioning for obstructive sleep apnoea in Pierre Robin sequence: A systematic review and meta-analysis

  • M Camacho, M W Noller, S Zaghi, L K Reckley, C Fernandez-Salvador, E Ho, B Dunn, D K Chan
  • Journal:
    The Journal of Laryngology & Otology / Volume 131 / Issue 5 / May 2017
    Published online by Cambridge University Press:
    14 February 2017, pp. 378-383
    Print publication:
    May 2017
  • Objective:

    To search for studies on tongue–lip adhesion and tongue repositioning used as isolated treatments for obstructive sleep apnoea in children with Pierre Robin sequence.

    Methods:

    A systematic literature search of PubMed/Medline and three additional databases, from inception through to 8 July 2016, was performed by two authors.

    Results:

    Seven studies with 90 patients (59 tongue–lip adhesion and 31 tongue repositioning patients) met the inclusion criteria. Tongue–lip adhesion reduced the mean (± standard deviation) apnoea/hypopnoea index from 30.8 ± 22.3 to 15.4 ± 18.9 events per hour (50 per cent reduction). The apnoea/hypopnoea index mean difference for tongue–lip adhesion was −15.28 events per hour (95 per cent confidence interval = −30.70 to 0.15; p = 0.05). Tongue–lip adhesion improved the lowest oxygen saturation from 75.8 ± 6.8 to 84.4 ± 7.3 per cent. Tongue repositioning reduced the apnoea/hypopnoea index from 46.5 to 17.4 events per hour (62.6 per cent reduction). Tongue repositioning improved the mean oxygen saturation from 90.8 ± 1.2 to 95.0 ± 0.5 per cent.

    Conclusion:

    Tongue–lip adhesion and tongue repositioning can improve apnoea/hypopnoea index and oxygenation parameters in children with Pierre Robin sequence and obstructive sleep apnoea.

  • Management of upper airway obstruction in Pierre Robin sequence

  • A. P. Bath, P. D. Bull
  • Journal:
    The Journal of Laryngology & Otology / Volume 111 / Issue 12 / December 1997
    Published online by Cambridge University Press:
    29 June 2007, pp. 1155-1156
    Print publication:
    December 1997

  • Pierre Robin sequence (PRS) presents in the neonatal period with upper airway obstruction and feeding difficulties. Infants with pronounced micrognathia may fail to thrive because of chronic airway obstruction, or experience severe respiratory distress. This is potentially fatal and surgical intervention in these cases is necessary. We present our series of cases with severe PRS requiring surgical relief of their airway obstruction, and the reasons for preferring tracheostomy over glossopexy.

  • Pierre Robin syndrome: characteristics of hearing loss, effect of age on hearing level and possibilities in therapy planning

  • Jadranka Handžić-Ćuk, Višeslav Ćuk, Ranko Rišavi, Vladimir Katić, Damir Katušić, Marijo Bagatin, Smiljana Štajner-Katušić, Damir Gortan
  • Journal:
    The Journal of Laryngology & Otology / Volume 110 / Issue 9 / September 1996
    Published online by Cambridge University Press:
    29 June 2007, pp. 830-835
    Print publication:
    September 1996

  • Hearing loss was studied in 22 patients with Pierre Robin syndrome (PRS) aged three to 12 years (median 5.0 years). The results were compared to those obtained in 62 patients with isolated cleft palate (ICP) aged one to 27 years (median 5.5 years). Hearing loss was more frequently found in PRS (73.3 per cent) than in ICP (58.1 per cent) patients (p = 0.02). PRS patients had more ears with moderate (21–40 dB) and severe (>40 dB) hearing loss, disturbing their social contact, with no tendency to normalization with age (Spearman r = 0.065). In contrast to PRS, ICP patients showed a significant tendency to hearing level normalization with ageing (Spearman r = −0.453; p = 0.001). Planigraphs of temporal bones showed inadequately developed pneumatization of the mastoid bone in all PRS patients and in most ICP patients. No malformation of the inner or middle ear was found in either group. PRS patients have a significantly higher risk of conductive hearing loss than those with ICP. Use of tympanostomy (ventilation) tubes is therapy of choice in patients with Pierre Robin syndrome, and it should be introduced as early as possible, even at the same time as palatoplasty.