An increasing body literature has underscored the need for clinical methods and approaches to be able to generalise to clients from different cultural backgrounds. This has led to a broader discussion on the unique needs of offenders and patients from minority and culturally and linguistically diverse (CALD) backgrounds and how forensic clinicians can work more effectively with these populations. As cultural differences can affect illness and behaviour, recognising these differences is important for appropriate and equitable mental health care provision within the criminal justice system. This chapter provides an outline of the unique socio-cultural contexts of Culturally and Linguistically Diverse populations and how these phenomena underpin mental health presentations and behaviours prompting criminal justice system involvement. Directions are offered for working with such populations in various psycho-legal contexts (i.e., clinical assessment, diagnoses, treatment, risk assessment), and an integrated model of cross-cultural assessment is introduced to assist assessors working in cross-cultural clinical scenarios.