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This chapter introduces the central ideas in Darwin’s Expression, poses the main interpretive questions that scholars have raised, and outlines my answers to those questions. Why does Darwin analyze expressions in terms of heritable habits, recalling Lamarck’s debunked theory of evolution, when his own theory of natural selection provides a superior alternative? My answer is that Darwin embraces Hartley’s associationist theory of mind, which posits habit as the basis of thought. I claim that multiple puzzling features of Expression are resolved once we view Darwin as an associationist philosopher.
This chapter traces the development of Darwin’s theory of emotion and expression from 1838 to 1872, emphasizing his many engagements with associationist philosophers. I demonstrate that all three of Darwin’s principles of expression are derived from the works of associationist philosophers, especially David Hartley, Erasmus Darwin, Herbert Spencer, and Alexander Bain.
This chapter surveys associationist theories of emotion leading up to Darwin’s Expression. These theories analyze emotions as sequences of thoughts, feelings, and actions, linked together by principles of association. Thomas Hobbes contributes to this tradition the idea that emotions can be analyzed as “trains of thoughts.” John Locke contributes the idea that these trains are connected by the “association of ideas.” David Hume contributes the idea that association can occur via contiguity, resemblance, or cause and effect. David Hartley puts these ideas together to present the first full-fledged associationist theory of mind and emotion. Harley’s ideas are developed further by Joseph Priestley, Erasmus Darwin (Charles’s grandfather), Thomas Brown, James Mill, Alexander Bain, and Herbert Spencer, among others. This tradition in the philosophy of emotion has never before been described or analyzed.
Janum Sethi investigates Kant’s application of hylomorphism to the theory of self-consciousness, as evident in the distinction he draws between transcendental and empirical apperception. According to Sethi, the standard reading of this distinction overlooks that it is drawn in terms of a distinction between transcendental and empirical unity of apperception, which can be traced to the distinct natures of the two faculties that produce these unities: whereas the former is brought about according to the rational laws of the understanding, the latter is a result of the psychological laws of the imagination. In light of this, Sethi argues that the two types of apperception amount to a subject’s awareness of two cognitively essential aspects of herself: namely, her spontaneity and her receptivity – that is, of her capacity to receive the material for cognition through the senses and of her capacity to impart a certain form to this material through the use of the understanding.
Charles Darwin is known as a biologist, geologist, and naturalist, but he was also a philosopher. This book uncovers Darwin's forgotten philosophical theory of emotion, which combines earlier associationist theories with his theory of evolution. The British associationists of the eighteenth and nineteenth centuries argued that the mind operates primarily through the association of ideas, and that emotions are strings of thoughts, feelings, and outward expressions, connected by habit and association. Charles Darwin's early notebooks on emotion reveal a keen interest in associationist philosophy. This book shows that one of his final works, The Expression of the Emotions in Man and Animals (1872), is a work of associationist philosophy, and analyzes Darwin's revolutionary idea: that if the associations that produce emotions can be inherited, then the theory of evolution can explain how emotions first occurred in simpler organisms and then developed and were compounded into the complex experiences humans have today.
Cognitive impairment in major depressive disorder (MDD) may be driven by neuro-inflammatory processes involving pro-inflammatory cytokines.
Aims
This study aimed to examine the relationship between serum tumour necrosis factor-alpha (TNF-α) levels and cognitive performance across different domains in individuals with MDD.
Method
Sixty patients with MDD and 60 healthy controls were recruited. Cognitive function was assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), and serum TNF-α levels were measured via flow cytometry.
Results
After adjusting for covariates, RBANS total and subscale scores were significantly lower in MDD patients compared with controls (P < 0.001), while log10-transformed TNF-α levels were significantly higher in the MDD group (P = 0.006). In MDD patients, log10TNF-α levels were inversely correlated with immediate memory scores after adjusting for confounding factors (r = −0.35, P = 0.009); however, this relationship was not observed in healthy controls (r = −0.02, P = 0.90). Stepwise multivariate regression analysis further confirmed the negative association of log10TNF-α with immediate memory scores in MDD patients (β = −14.58, t = −4.14, P < 0.001), but not in healthy controls (β = −0.02, t = −0.14, P = 0.89).
Conclusions
These findings suggest that elevated serum TNF-α may contribute to the pathophysiology of MDD and is specifically associated with deficits in immediate memory.
We have seen how imagination can plausibly be taken to be part of a perceptual referential apparatus. Sensory imaginations therefore contribute to the fulfillment of an empirical intuition’s cognitive roles. The aim of the analysis in this chapter is three-fold: (1) to throw more light upon what is added by imagination to empirical cognition of objects, in the form of perceptual memories and quasi-perceptual anticipations – this is lower order objectification that goes beyond mere perceptual objectification in its own right but which may also be part of higher order objectification through concepts; (2) to show how imagination that mixes with perceptions may also lead to false perceptual judgments – misperception is a topic of this chapter, whereas hallucination is discussed in Chapter 9; (3) to bring out the lack of reality-character of fictional imaginations, even when these imitate perceptions, so as to throw more light upon the nature of perceptions.
A survey found that 1 in 6 (16%) of children aged between 5 and 16 years has a probable mental illness. Furthermore, research has shown that most of these disorders have their origins in childhood, even if they are typically diagnosed in adulthood. Childhood represents a critical period of physical, cognitive, psychological, behavioural and social transformation. Identifying risk and protective factors that alter the typical developmental trajectory could have long-term educational, social, societal and economic implications. This chapter will address what is meant by the term risk factor and how these can be identified, provide examples of risk factors thought to be important in child and adolescent psychiatry. It concludes with some case vignettes to highlight the importance of taking a developmental biopsychosocial approach to identifying risk, considering predisposing, precipitating, perpetuating and protective factors.
This chapter contends that colonial-era rules permeated EEC development cooperation through the European Development Fund. But more importantly, it shows that with personnel transitions from colonial to European administrations, a colonial attitude towards legal compliance was transferred within the European Commission.
Parkinson’s disease (PD) is a prevalent neurological disorder and the second most common neurodegenerative disease. Research has explored the impact of infectious agents, such as the parasites, on neurological conditions, including PD. Given the limited studies worldwide and in Iran, this study aims to investigate the relationship between Toxocara infection and PD. This case-control study involved 91 PD patients and 90 healthy controls. After obtaining consent, serum samples and questionnaires were collected. All sera were examined using an ELISA test for IgG antibodies against Toxocara canis. Results were analyzed with SPSS, using chi-square tests, and odds ratios (OR), and confidence intervals (CI) were calculated via univariate and multivariate analyses. The prevalence of anti-Toxocara IgG was 33% (30/91) in PD patients and 33.3% (30/90) in the control group. Both univariate analysis (OR: 0.98; 95% CI: 0.52–1.82) and multivariate analysis (OR: 0.95; 95% CI: 0.49–1.83) indicated no statistically significant association. Additionally, univariate analysis (OR: 0.49; 95% CI: 0.16–1.5) and multivariate analysis (OR: 0.37; 95% CI: 0.09–1.43) suggested non-significant association between Toxocara infection and the severity of PD. Our findings do not support a statistically significant association between Toxocara infection and the PD. While the analysis suggested that Toxocara infection might reduce the severity of PD, these results were also not statistically significant. Further research with larger sample sizes and diverse populations is needed to fully understand the potential relationship between Toxocara infection and PD.
Numerous developmental findings suggest that infants and toddlers engage predictive processing during language comprehension. However, a significant limitation of this research is that associative (bottom-up) and predictive (top-down) explanations are not readily differentiated. Following adult studies that varied predictiveness relative to semantic-relatedness to differentiate associative vs. predictive processes, the present study used eye-tracking to begin to disentangle the contributions of bottom-up and top-down mechanisms to infants’ real-time language processing. Replicating prior results, infants (14-19 months old) use successive semantically-related words across sentences (e.g., eat, yum, mouth) to predict upcoming nouns (e.g., cookie). However, we also provide evidence that using successive semantically-related words to predict is distinct from the bottom-up activation of the word itself. In a second experiment, we investigate the potential effects of repetition on the findings. This work is the first to reveal that infant language comprehension is affected by both associative and predictive processes.
An information-theoretic framework is used to analyze the knowledge content in multivariate cross classified data. Several related measures based directly on the information concept are proposed: the knowledge content (S) of a cross classification, its terseness (Zeta), and the separability (GammaX) of one variable, given all others. Exemplary applications are presented which illustrate the solutions obtained where classical analysis is unsatisfactory, such as optimal grouping, the analysis of very skew tables, or the interpretation of well-known paradoxes. Further, the separability suggests a solution for the classic problem of inductive inference which is independent of sample size.
A latent variable representation for multiple-choice item and option characteristic curves is presented. Under standard assumptions of conditional independence of item responses and monotonicity of item characteristic curves, a criterion for distractors is proposed based on distractor selection ratios. A connection is made between the proposed criterion and the theory of individual choice behavior, providing new insight. The main results allow for the testing of the criterion from observable data without first specifying a parametric form for the characteristic curves. A series of examples apply the method.
A distinction is drawn between redundancy measurement and the measurement of multivariate association for two sets of variables. Several measures of multivariate association between two sets of variables are examined. It is shown that all of these measures are generalizations of the (univariate) squared-multiple correlation; all are functions of the canonical correlations, and all are invariant under linear transformations of the original sets of variables. It is further shown that the measures can be considered to be symmetric and are strictly ordered for any two sets of observed variables. It is suggested that measures of multivariate relationship may be used to generalize the concept of test reliability to the case of vector random variables.
In recent years there has been a marked escalation in the study of Graeco-Roman associations. Useable data for recreating associational groups usually derive from the inscriptions embedded in stone monuments that have survived in the material record. Because data of this kind usually originate from groups with middling economic resources, it is imperative to focus particular attention on any data emerging from groups lower on the socio-economic scale. The second-century b.c.e. papyrus fragments of SB 3.7182 from Philadelphia in Egypt are a prime resource in this regard, surfacing from what must have been one of the most inconspicuous of associations. This article offers a detailed investigation of the general prosopography of the low-level association comprising a few enslaved men. It proposes that ten meetings are evident in the heavily damaged associational ledgers; that the association consisted of enslaved members of three distinct households; that a subscription or epidosis was collected at one meeting; and that we get a rare glimpse of low-level generosity enacted within the association in relation to the payment of membership fees, as well as an extremely rare glimpse of the agency of the enslaved.
Chapter 10 examines correlation, the statistical procedure used to measure the degree of association or relationship between variables. It is bivariate, since we typically apply this statistical technique to measure or describe the association between two variables or groups. The correlation coefficient, which measures the degree and direction of an association, is discussed, as are some of the issues regarding the application and interpretation of correlations. The chapter also outlines the many different measures of association but focuses on Pearson’s r. It emphasizes the definitional formula and z-scores for understanding and computing the correlation coefficient.
This chapter addresses symmetry’s implications for expressive freedom and religious liberty. Symmetry supports maintaining First Amendment law’s current focus on neutrality, notwithstanding emerging critiques that this approach lacks a strong historical foundation and unduly limits governmental regulation of offensive or dangerous ideas. At the same time, symmetric interpretation counsels against expanding the emerging “First Amendment Lochnerism” that threatens to extend constitutional protections for free expression into areas of economic and workplace regulation. A preference for symmetry also supports protecting religious groups, when possible, through more general protections for freedom of expressive association rather than through religion-specific constitutional doctrines. Although religious liberty may once have been a symmetric principle, today religion-specific protections risk placing constitutional law on one side of a fraught political divide over religion’s place in public life.
The search for the causes of disease is an obvious central step in the pursuit of better health through disease prevention. In the previous chapters we looked at how we measure health (or disease) and how we look for associations between exposure and disease. Being able to identify a relation between a potential cause of disease and the disease itself is not enough, though. If our goal is to change practice or policy in order to improve health, then we need to go one step further and decide whether the relation is causal because, if it is not, intervening will have no effect. As in previous chapters, we discuss causation mainly in the context of an exposure causing disease but, as you will see when we come to assessing causation in practice, the concepts apply equally to a consideration of whether a potential preventive measure really does improve health.
This study aimed to evaluate the association between vegetable intake and major depressive disorder (MDD) through cross-sectional analysis and bidirectional two-sample Mendelian randomisation (MR).
Design:
Cross-sectional analysis was conducted on National Health and Nutrition Examination Survey (NHANES) data from 2005 to 2018 and the corresponding Food Patterns Equivalents Database (FPED). Genome-wide association study (GWAS) data were obtained from UK Biobank and Psychiatric Genomics Consortium (PGC) dataset. Logistic regression analysis was performed after calculating the weights of the samples. Inverse variance weighted, MR-Egger and weighted median methods were used to evaluate the causal effects.
Setting:
A Patient Health Questionnaire-9 score ≥ 10 was considered to indicate MDD. Low vegetable intake was defined as < 2 cups of vegetables per day.
Participants:
30 861 U.S. adults from NHANES. The GWAS data sample size related to vegetable intake were comprised 448 651 and 435 435 cases respectively, while the GWAS data sample size associated with MDD encompassed 500 199 cases.
Results:
There were 23 249 (75·33 %) participants with low vegetable intake. The relationship between vegetable intake and MDD was nonlinear. In the multivariate model adjusted for sex, age, education, marital status, poverty income ratio, ethnicity and BMI, participants with low vegetable intake were associated with an increased risk of MDD (OR = 1·53, 95 % CI (1·32, 1·77), P < 0·001). Bidirectional MR showed no causal effects between vegetable intake and MDD.
Conclusions:
Cross-sectional analysis identified a significant relationship between vegetable intake and MDD, whereas the results from bidirectional two-sample MR did not support a causal role.
“Dream Defenders and the Inside Songs” explores the extent to which Percy Shelley's poetic legislation is able to counter racial divisiveness and antiBlackness in “our” communities and universities. It enlists Fred Moten’s poem “barbara lee” and Benjamin Zephaniah’s characterization of Shelley as the “original dub poet” to claim that what is “wholly political” about the semantic and sonic relays activated in Shelleyan songs is their capacity to disrupt the associational logics undergirding white-body supremacy and literary Anglo-Eurocentrism. Tracking the process enacted in “barbara lee,” by which reliance on “the inside songs” enables Representative Lee to vote against President Bush’s military authorization act, the chapter proposes some pedagogical and creative-critical revisions to Shelley studies that might effect a similar “inside outward opening” of Shelley. Leftist celebrations of “Red Shelley” have emphasized the collective and street-performative dimensions of his then-unpublished protest songs. The chapter probes the salience of a “black” Shelley by recasting two familiar Shelleyan devices. One emphasizes sound’s activation of embodied knowledge that circumvents the priority granted to textual literacy. A second accentuates association as a process that expands the affective-cognitive connections mobilized by a word and by encounters with another person. In other words, the intimacy between who we know and what we know is an underacknowledged fact of scholarly method. Diversifying one is key to diversifying the other in an ongoing cycle. Cultivating the two promises to transform “defenses” of poetry into live performances of antiracism.