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Accepted manuscript

Associations of linear growth trajectories from 0-5 years with cognitive function and school achievement at 10 years of age: The Ethiopian iABC birth cohort study

Published online by Cambridge University Press:  29 December 2025

Rahma Ali*
Affiliation:
Department of Population and Family health, Faculty of Public Health, Jimma University, Jimma, Ethiopia. Department of Nutrition, Exercise, and Sports, University of Copenhagen, Copenhagen, Denmark.
Suzanne Filteau
Affiliation:
Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Jonathan CK Wells
Affiliation:
Population, Policy and Practice Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Beakal Zinab
Affiliation:
Department of Nutrition, Exercise, and Sports, University of Copenhagen, Copenhagen, Denmark. Department of Nutrition and Dietetics, Faculty of Public Health, Jimma University, Jimma, Ethiopia.
Bikila S Megersa
Affiliation:
Department of Nutrition, Exercise, and Sports, University of Copenhagen, Copenhagen, Denmark.
Daniel Yilma
Affiliation:
Department of Internal Medicine, Faculty of Medical Sciences, Jimma University, Jimma, Ethiopia.
Tsinuel Girma
Affiliation:
Department of Pediatrics and Child Health, Faculty of Medical Sciences, Jimma University, Jimma, Ethiopia.
Dorothea Nitsch
Affiliation:
Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Mette F Olsen
Affiliation:
Department of Nutrition, Exercise, and Sports, University of Copenhagen, Copenhagen, Denmark. Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
Henrik Friis
Affiliation:
Department of Nutrition, Exercise, and Sports, University of Copenhagen, Copenhagen, Denmark.
Akanksha A. Marphatia
Affiliation:
Population, Policy and Practice Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Rasmus Wibaek Christensen
Affiliation:
Clinical and Translational Research, Copenhagen University Hospital – Steno Diabetes Center Copenhagen, Herlev, Denmark
Mubarek Abera
Affiliation:
Department of Psychiatry, Faculty of Medical Sciences, Jimma University, Jimma, Ethiopia
*
Corresponding author: Rahma Ali; PhD fellow at Jimma university and University of Copenhagen Email: rahmiii.ali@gmail.com Phone number +251911597642
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Abstract

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This study aimed to identify linear growth trajectories from 0-5 years and assess their associations with cognitive function and school achievement in Ethiopian children aged 10 years. Latent class trajectory modelling was used to identify distinct height-for-age (HAZ) trajectories. Cognitive function was assessed using the Peabody Picture Vocabulary Test (PPVT), while school achievement was measured by Math, English, and Science (MES) combined scores and grade-for-age. Associations were assessed using multiple linear or logistic regressions.

We identified 4 distinct HAZ trajectories. Decreasing trajectory (n=145, 31.9%) started high at birth but dropped sharply. The increasing-decreasing trajectory (n=196, 43.2%) increased up to 3 months followed by a decrease. The stable low (n=74, 16.3%) had low HAZ at birth, followed by a slight decrease. The rising trajectory (n=39, 8.6%) started low but then increased to HAZ above, yet close to zero. At 10 years, children in the rising trajectory had 4.54 (95% CI: -0.45, 9.55, p=0.075) higher MES combined score and 2.4 times (95% CI: 1.12, 5.15, p=0.025) higher odds of being in the appropriate grade-for-age compared to those in the increasing-decreasing trajectory. The association between stable low and decreasing trajectory with appropriate grade-for-age had odds ratio close to null.

In conclusion, we found that three of the four linear growth trajectory classes showed a declining pattern. Data suggest that greater linear growth in early childhood may be associated with higher school achievement and better cognitive function.

Information

Type
Research Article
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of The Nutrition Society

Footnotes

*

Joint senior authors.