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Current state of mental health and substance use in Toledo, Belize: A mixed methods study

Published online by Cambridge University Press:  22 May 2025

Jaclyn Kirsch*
Affiliation:
School of Social Work, University of Texas at Arlington, Arlington, TX, USA
Megan Fabbri
Affiliation:
School of Social Work, West Virginia University, Morgantown, WV, USA
Kristen Kerr
Affiliation:
School of Social Work, University of Texas at Arlington, Arlington, TX, USA
Lynette Gomez
Affiliation:
Hillside Health Care, Eldridge, Toledo, Belize
*
Corresponding author: Jaclyn Kirsch; Email: jaclyn.kirsch@uta.edu
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Abstract

Mental health and substance use are increasingly pressing issues in communities across low-and-middle income countries, including Belize, particularly Toledo, the country’s most rural and resource-limited district. Using community-based participatory research methods, this preliminary mixed methods study (quantitative n = 163; qualitative n = 10) aims to (1) investigate mental health symptoms and substance use patterns in a non-randomized sample of individuals from southern Belize and (2) explore community perspectives on mental health among community stakeholders. Findings show high levels of depression, anxiety, and suicidal ideation among survey participants, which were supported by qualitative interviews. While low levels of substance use were reported by survey participants, qualitative findings diverged and showed alcohol use to be of significant concern among participants. Our study highlights the critical need for increased research, advocacy, and policy implementation regarding mental health and substance use in Toledo and across Belize. Given the scarcity of mental health resources in Toledo, findings underscore the urgent need for policy interventions that expand access to psychiatric services, integrate community-based mental health approaches, and address socioeconomic drivers of poor mental health outcomes.

Type
Research Article
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press

Impact statement

This paper is one of the first known studies that reports on mental health and substance use among a sample of community members in the country of Belize. The findings of our study are imperative to increase understanding of mental health and substance use among this population and will assist in bringing awareness to the topic among stakeholders. The high levels of mental health symptoms among study participants show the critical need for increased support and understanding of mental health in the country. Locally, this study brings awareness to the topic of mental health and substance use and highlights the need for more research, advocacy, and policy on the topic.

Introduction and background

Mental health continues to grow as a critical social work and public health concern around the world. Currently, 80% of the global mental health disease burden occurs in low- and middle-income countries (LMIC; Alloh et al., Reference Alloh, Regmi, Onche, van Teijlingen and Trenoweth2018). Alongside mental health concerns, substance use has emerged as a significant issue, often exacerbating existing mental health conditions (Nadkarni et al., Reference Nadkarni, Gandhi, Bhatia and Velleman2023). While research and understanding of mental health and its treatment in low resourced areas has dramatically increased in recent decades (Sweetland et al., Reference Sweetland, Oquendo, Sidat, Santos, Vermund, Duarte, Arbuckle and Wainberg2014; Keynejad et al., Reference Keynejad, Spagnolo and Thornicroft2021), many communities continue to have limited capacity to screen, diagnose, and treat mental health and substance use concerns. In the Caribbean, where an understanding of mental health and substance use is limited, it is difficult to approximate the rates of mental health diagnoses despite the fact that mental health disorders account for an estimated quarter of the disease burden in the Latin America and Caribbean region (Pan American Health Organization, 2013). Tracking substance use in the region is also challenging, and precise rates are difficult to determine; however, the region has a long history of substance use deeply embedded in its culture, characterized by high levels of alcohol consumption, marijuana cultivation, and its role as a significant hub for drug trafficking (Reid et al., Reference Reid, Downes and Khenti2015). One such country is Belize, a small, diverse country in Central America. According to the Belize Ministry of Health and Wellness (2023), no epidemiological study on mental health or substance use has been conducted, posing a challenge in assessing the overall well-being of the population. Additionally, Toledo, the southernmost district of Belize, is the most rural and least resourced, which exacerbates challenges for communities in accessing mental health and substance use services. Given the limited understanding of mental health and substance use in Belize, coupled with the heightened vulnerabilities faced by residents of Toledo, this study seeks to enhance knowledge of the current state of mental health and substance use within Toledo, Belize.

Belize and Toledo

Belize is situated in Central America between Mexico, Guatemala, and Honduras. Despite having a population of fewer than 500,000 people, the country is remarkably diverse, with a wide array of ethnicities and languages (World Bank, 2022). The country’s history of British colonialism has a profound impact on its socio-political and cultural landscape. The introduction of British colonial structures led to the displacement and marginalization of Indigenous Mayan communities, whose struggles for land rights and cultural recognition continue today (Shoman, Reference Shoman2010). Although Belize is classified as a middle-income country, rural areas face significant economic disparities with limited access to essential services like healthcare, education, and infrastructure (Government of Belize, 2010). The legacy of colonialism has contributed to structural inequalities, with indigenous and Afro-Belizean communities disproportionately affected by poverty, particularly in the Toledo district (Minority Rights Group, 2017). As the most rural district in Belize (Statistical Institute of Belize, 2023), Toledo is home to the highest percentage of Indigenous people, including the majority of the country’s Mayan population—its poorest ethnic group (Gahman et al., Reference Gahman, Penados and Greenidge2020). The availability of social services, including access to mental health and substance use providers, throughout Toledo is notably limited, exacerbating the challenges faced by its residents (Belize Ministry of Economic Development, 2010).

Mental health and substance use in Belize

The recognition and understanding of the need for mental health and substance use services in Belize have paralleled global trends over the past several decades. Before the 1990s, the country was not actively acknowledging the need for mental health care and continued the colonial era institutional models where those who were severely mentally ill were put into the single psychiatric hospital in the country and most others were left untreated (Killion and Cayetano, Reference Killion and Cayetano2009). In 1991, the first training program was established for psychiatric nurse practitioners through the Pan American Health Organization (PAHO) to provide community-based care throughout the country (World Health Organization, 2009). While at the time this program was seen as incredibly successful in supporting the mental health of Belizeans, it currently is not meeting growing need as there are just 13 psychiatric nurse practitioners (PNP) working in the country through this program (Estephan et al., Reference Estephan, Pu, Bermudez and Waits2023). The persistent shortage of PNPs limits the availability and accessibility of services across the country, especially in rural areas like Toledo. This is exacerbated by insufficient training opportunities and resources for new PNPs, hindering the program’s sustainability and ability to expand to meet current demands.

In Toledo specifically, the rural nature of the district, higher levels of poverty, and large Indigenous population lead to both increased mental health concerns and more limited access to structural supports for treatment options. This severely restricts access to care for residents of the district’s 50+ villages, most of which are Indigenous communities with distinct conceptualizations of mental health that differ from traditional Western models, necessitating culturally specific treatment approaches (Hatala and Waldram, Reference Hatala and Waldram2016). Many people living in Toledo, especially Indigenous Mayans, are more likely to seek treatment from traditional healers rather than providers in hospitals and clinics (Rich et al., Reference Rich, Gentle-Genitty, Estrada, Rich and Ramkumar2022).

A key barrier to instilling appropriate mental health services in Belize is increasing the understanding of mental health concerns in the country. The recent National Mental Health Policy 2023–2028, released by the Belize Ministry of Health and Wellness (2023), provides information on mental health diagnostic categories from the Belize Health Information System (BHIS). The data reveal that among 11,312 recorded mental health visits from 2018 to 2021, the top three diagnoses were anxiety disorders (45%), affective disorders (22%), and schizophrenia and related disorders (8%). The report also showed that 32 people died by suicide (7.63/100,000 death rate) (Ministry of Health and Wellness, 2023). Within this report, no specific information was provided on the rate of those being treated for substance use disorders. In a study of patients from a primary care clinic in Belize City, researchers found that depression and anxiety were the most common diagnoses, with prevalence rates surpassing those reported in primary care clinics in other countries (Oladeji et al., Reference Oladeji, Simmons and Baitwabusa2024). No studies estimating the rates of substance use in Belize could be identified. The lack of comprehensive data on mental health and substance use in Belize hampers a full understanding of community needs, with particularly scarce information on the specific challenges faced in southern Belize.

The mental health treatment gap in Belize reflects broader trends in LMICs, where stigma, resource limitations, and workforce shortages hinder access to care (Evans-Lacko et al., Reference Evans-Lacko, Aguilar-Gaxiola, Al-Hamzawi, Alonso, Benjet, Bruffaerts, Chiu, Florescu, de, Gureje, Haro, He, Hu, Karam, Kawakami, Lee, Lund, Kovess-Masfety, Levinson, Navarro-Mateu, Pennell, Sampson, Scott, Tachimori, ten, Viana, Williams, Wojtyniak, Zarkov, Kessler, Chatterji and Thornicroft2018). This issue is particularly severe in rural areas like Toledo, where a shortage of mental health professionals and treatment facilities leaves many without adequate support (Nadkarni et al., Reference Nadkarni, Gandhi, Bhatia and Velleman2023). Belize relies on a small number of psychiatric nurse practitioners, mirroring challenges in other under-resourced settings where community-based services remain underdeveloped (Keynejad et al., Reference Keynejad, Spagnolo and Thornicroft2021). High levels of stigma further discourage individuals from seeking treatment, widening the gap between those in need and those who receive care. As a result, clinical samples fail to capture the true extent of mental health and substance use challenges in the broader population (Evans-Lacko et al., Reference Evans-Lacko, Aguilar-Gaxiola, Al-Hamzawi, Alonso, Benjet, Bruffaerts, Chiu, Florescu, de, Gureje, Haro, He, Hu, Karam, Kawakami, Lee, Lund, Kovess-Masfety, Levinson, Navarro-Mateu, Pennell, Sampson, Scott, Tachimori, ten, Viana, Williams, Wojtyniak, Zarkov, Kessler, Chatterji and Thornicroft2018).

The current study

To address this research gap, our research team, in partnership with a local healthcare non-profit, sought to investigate rates of mental health and substance use among a population of individuals living in Toledo, Belize. Existing data on mental health and substance use in Toledo, Belize was limited and primarily drawn from clinical populations, leaving a gap in understanding among community-based individuals not actively engaged in treatment. To begin addressing this gap, this study aims to (1) examine the presence and patterns of mental health symptoms and substance use in a non-randomized community sample and (2) explore community perspectives on mental health through qualitative stakeholder interviews, providing critical insights into an understudied population. These preliminary findings contribute to the literature by providing insights into the current state of mental health and substance use in southern Belize, highlighting key areas for further research and intervention.

Methods

Design

This study was co-developed by the lead researcher and the Executive Director of a local non-profit healthcare organization in Toledo, Belize in response to the clinic’s growing concerns about the mental health of its patients. The organization, a trusted provider in the community, offers free healthcare through its main clinic near Punta Gorda and a mobile clinic serving villages across the district. While it has no dedicated mental health practitioners, concerns are referred to the Ministry of Health. Recognizing the need for improved mental health support, the organization sought to better understand community needs and inform future efforts to enhance well-being.

We implored a community-based participatory research approach (CBPR) throughout the entirety of the project (Wallerstein et al., Reference Wallerstein, Duran, Oetzel and Minkler2017), beginning with the establishment of an advisory committee that consisted of three staff members of the partner organization. This group met regularly throughout the project to assist in development of the study, recruitment of participants, data collection, and data analysis. Our study used an exploratory sequential mixed methods design (Creswell, Reference Creswell2014), where Phase I consisted of qualitative interviews with staff members of the partner organization (N = 10) that then directly informed the variables measured in Phase II where a quantitative survey was completed by community members (N = 163). A mixed methods approach was chosen to provide a more comprehensive understanding of mental health and substance use in Toledo as quantitative data allowed for the identification of symptom patterns, while qualitative insights captured community perspectives and contextual factors influencing mental health and substance use. This integration of methods ensured a deeper exploration of the topic beyond what either approach could achieve alone. The study was approved by the Institutional Review Board at the study site.

Phase I: Qualitative

In April 2021, the first author conducted 10 virtual semi-structured interviews via Zoom due to COVID-19 travel restrictions. Interviews, lasting 45–90 minutes, were conducted in English with staff from the partner healthcare organization, including community health workers, clinic staff, and outreach coordinators. Staff members on the advisory committee were not eligible to complete an interview. Participants provided diverse perspectives on mental health and substance use, drawing from both their professional roles and lived experiences as community members of Toledo. Given the stigma surrounding mental health, staff members were selected for their existing relationship with the first author, ensuring a more open discussion. The virtual format limited opportunities to build trust with external community members, making staff the most suitable participants. This approach facilitated candid discussions while prioritizing participant comfort and confidentiality.

Participants completed a short demographic questionnaire and consented to participate in the study before each interview. Questions were developed in partnership with the advisory committee and aimed to uncover participants’ viewpoints on mental health in the Toledo community, including perceptions of depression, anxiety, and substance use, as well as barriers to care, and the impact of the COVID-19 pandemic on well-being. Interviews were recorded, and transcriptions were generated using Zoom before being manually reviewed to ensure accuracy. Data collection ceased when saturation was met.

Phase II: Quantitative

The quantitative survey was developed using both results of the qualitative interviews and input from the advisory committee to create and collect data that would be meaningful and useful in improving services. All scales were reviewed with the advisory committee to assess questions applicability to the Belizean cultural context. All questions and scales were found to be acceptable, and no changes were made. Survey data were collected via three staff members from the partner organization who were different than members of the advisory committee. The data collectors had no prior experience with data collection and were not trained mental health professions. Therefore, the research team provided training on data collection methods and ethical research practices, including best practices in collecting mental health data and handling sensitive topics. Training emphasized strategies for addressing potential concerns arising from asking community members stigmatized or personal questions about their mental health. They additionally completed the Collaborative Institutional Training Initiative (CITI) training on Human Subjects Research (HSR) to understand best practices in human subjects research. They used snowball sampling to recruit participants, a common approach when conducting research with understudied and hard-to-reach populations (Goodman, Reference Goodman2011).

Study participants in Phase II included any adult residing in the Toledo district, regardless of mental health history or healthcare engagement. This community-based sample was essential for capturing a broader understanding of mental well-being beyond clinical populations as previous research in Belize has primarily focused on individuals receiving treatment for mental health conditions. By including participants from the general community, this study provides a more comprehensive perspective on mental health and substance use patterns among the wider population. Because this study utilized non-randomized, snowball, and convenience sampling, a formal sample size calculation was not conducted as the recruitment process did not rely on probability-based sampling. Instead, participant recruitment was facilitated through community networks, allowing access to individuals who might otherwise be difficult to engage in mental health research. While this limits generalizability, it provides valuable insight into an understudied population and helps establish a foundation for future research. At the conclusion of the survey, participants were then asked if they knew others who may be interested in participating. Participants did not receive an incentive for their participation based on feedback from the advisory committee. Data collection concluded when data collectors reported they could no longer identify participants to complete the survey.

Measures

The PHQ-9 and GAD-7, widely validated tools for assessing depression and anxiety (Kroenke et al., Reference Kroenke, Spitzer and Williams2001; Spitzer et al., Reference Spitzer, Kroenke, Williams and Löwe2006), were used in this study. These measures have been applied in resource-limited settings, including the Caribbean (Carroll et al., Reference Carroll, Hook, Perez, Denckla, Vince, Ghebrehiwet, Ando, Touma, Borba, Fricchione and Henderson2020). Given the lack of prior validation in Belize, we report reliability statistics (PHQ-9: α = .84; GAD-7: α = .88) to assess scale performance in this context. All reported information on suicidal thoughts came from the final item of the PHQ-9, which asks participants whether they have had thoughts of self-harm or being better off dead in the past two weeks. Additionally, substance use was assessed using a self-reported frequency scale, where participants indicated their use of alcohol, cigarettes, and marijuana over the past month. Because this study aimed to capture general substance use patterns rather than diagnose substance use disorders, a frequency-based measure was sufficient and allowed for a straightforward assessment without the need for a diagnostic, validated scale.

Data analysis

Data for each phase was first analyzed separately before being integrated. We utilized thematic analysis, following Clarke and Braun (Reference Clarke and Braun2017), with a deductive coding approach to examine qualitative data (Fereday and Muir-Cochrane, Reference Fereday and Muir-Cochrane2006). The data were analyzed and coded based on predefined mental health concerns, specifically focusing on depression and suicide, anxiety, and substance use. This method enabled us to systematically identify and interpret patterns related to these key issues within the participant responses. Multiple rounds of coding were completed by the second and third author based on the mental health concerns of interest. Initially, they familiarized themselves with the data by reading the transcripts multiple times. This immersion in the data facilitated a deep understanding of the context and nuances within the participants’ narratives. They then applied the predefined codes to the data, categorizing segments of text that aligned with the mental health concerns under investigation. Throughout this process, they engaged in regular discussions with the first author and the advisory committee to resolve any discrepancies and refine the coding framework, ensuring that it accurately reflected the participants’ experiences and perspectives. This collaborative approach helped us to enhance the rigor of the analysis as it minimized the potential for individual bias and ensured that the coding was both comprehensive and nuanced.

Quantitative survey data were analyzed using descriptive statistics, including frequencies and percentages in SPSS 27. Qualitative and quantitative results are reported together with themes being developed based on the distinct mental health outcomes measured in the quantitative survey, with the qualitative findings being integrated through a weaving technique, a process where quantitative and qualitative findings are reported on a concept-by-concept basis (Fetters et al., Reference Fetters, Curry and Creswell2013). As a form of member checking, the advisory committee and two staff members who participated in the interviews reviewed and approved the results section to ensure accuracy and alignment with community perspectives.

Results

Table 1 shows the demographic details of both the qualitative and quantitative samples. Interview participants mostly identified as female (80%), between 30 and 39 years old (60%), Ketchi (40%), and married (70%). A majority of survey participants identified as female (58.3%), between 25 and 29 years (37.4%), Ketchi (39.9%), and married (55.8%). Survey data were similar to data from the 2022 Belize Census for Toledo where just over half of the citizens are female (50.7%), around half are Ketchi (49.4%), and a little over half are married or partnered (56.4%).

Table 1. Demographic characteristics of study participants (N = 173)

Depression and suicide

Table 2 shows the results from the PHQ-9. Quantitative data found that a majority of the survey respondents showed mild or no depressive symptoms (63.8%). However, 31.4% of respondents scored above the cut-off for depression, with 20.9% having moderate, 7.4% having moderately severe, and 3.1% having severe depressive symptoms. Qualitative participants supported these findings, stating that they observed sadness and depressive symptoms among community members. One participant noted:

I would say there is depression. Sometimes we require, you know, to visit them [patients] more often or have emotional support for them as well. Yeah, we also do hospice and palliative care like if a family member dies, then we follow up with them, because you know…that grieving stage that sometimes lead to depression as well (10).

Table 2. Depression and suicide (PHQ-9)

Others agreed saying, “I think there is some sadness and depression in our community, for sure” (2) and “That’s an issue in the community, people they don’t really do anything about it” (5). Participants noted that reasons for depression included financial concerns and family stress, with the two causes often overlapping. One participant stated: “There is a lot of people that don’t have jobs, they don’t have as good of income to provide for the family all these stress, things like that, people get depressed” (4). Another noted, “I think I see some sadness and depression, especially from couples who was breaking up. And their families who have problems, like a mother and a father who has problems and are fighting” (3).

In quantitative data, suicidal thoughts emerged as a concern. In the past two weeks, 62% of respondents reported having no thoughts of being “better off dead or of hurting yourself in some way.” However, 17.8% indicated experiencing these thoughts several times a day, 6.1% reported such thoughts on more than half the days, and 8% experienced them daily. Most qualitative participants stated that suicide does happen, but it is rare. When asked directly, participants stated: “I would say it’s not really, it’s not really at a high rate right now. But it does happen now and then.” (10), and “No, it is not something we really see in the community” (1). However, many participants noted anecdotal experiences of being told about suicidal thoughts from someone or seeing reports in the media. One participant noted that a family member who was experiencing domestic violence reported suicidal thoughts: “There was once she said I wish I could just kill myself. Sometimes she thinks of just going and running in the bushes” (3). Another stated, “Well, in our village, we hardly hear that. We don’t have people like that, but over the news, over the news we would hear that” (6). Participants noted that the most common methods of suicide in the community were hanging and by ingesting poison. Participants also noted that those who did commit suicide tended to be men: “Well, when it comes to suicide with women, women scarcely would do that [suicide]. It’s mostly the men that commit suicide here in our country. I would say, like 90% it’s men that commit suicide” (9).

Anxiety

Table 3 shows the results of the GAD-7. Quantitative and qualitative findings supported the notion that anxiety is a critical concern among community members. In the quantitative data, 36.2% of participants scored above the threshold for probable generalized anxiety disorder. Regarding anxiety severity, 29.4% of participants exhibited mild anxiety, 18.4% showed moderate anxiety, and 11% presented with severe anxiety symptoms. Qualitative findings revealed that participants strongly connected anxiety and stress to mental health. One participant stated:

Mental health for me is basically my own thinking, it does not really have to be like some kind of psychosis but like I said earlier, it could be you know, anxiety, those, you know, those illnesses that are really not really easily expressed by people that are suffering from it (10).

Table 3. Anxiety (GAD-7)

Participants reported an increase in stress among community members, particularly after the COVID-19 pandemic, due to concerns about health and the financial impact on individuals. One participant stated:

I think it’s [COVID-19] impacted a lot of people, because a lot of people here they were working half of their job, half of their pay, water pay, some lost it and they were really stressed out. Everywhere you hear people talking like man this is one of the worst I’ve been (3).

Participants often noted the connection between stress and physical sickness, stating concern over community members’ high levels of stress and the impact on health. One person noted, “Yeah I cannot stress enough on that, because stress is the number one cause for hypertension and diabetes” (4). When asked if finances were a cause of stress among community members, one participant stated:

Oh that’s, that everybody. That’s everybody’s stress here, but I do not know, right, but that’s the biggest stress. Money, income and not only the money, the cost of living, the groceries in the store they went sky high, the price rise. You know in this hard time that’s another stress because you are wondering how you could stretch or how you could divide that little money, to buy those things that went so high (9).

Substance use

Findings regarding substance use (see Table 4) presented a notable divergence: while survey data reflected limited substance use overall, qualitative findings indicated high levels of substance use, particularly among men. A majority of survey participants stated that they had never used any substances. The most commonly reported substance used was alcohol (20.3%). Two participants (1.2%) stated smoking every day, three participants (1.8%) reported using marijuana every day, and none reported smoking cigars, consuming alcohol, using chewing tobacco, or using other drugs every day. About half of participants (54.6%) reported never consuming alcohol and a majority reported never heavily drinking (71.8%).

Table 4. Substance use

Interview participants stated high levels of concern for substance use in the community, mainly alcohol consumption among men. One participant stated: “Substance abuse [is a key problem] because alcoholism, and you know in Belize people consume a lot of alcohol. Yeah I would say that is the biggest problem” (2). An increase in drinking was additionally noticed during the COVID-19 pandemic where stress and anxiety led to increased levels of drinking:

Alcohol use is very high here, yeah, people like drinking. Well, again because of COVID people were like locked up most of them so, then they had to stay home, so a lot resorted to drinking and stuff like that well drinking was always a problem here, but to me it grew more (1).

Finally, participants often discussed a connection between stress, alcohol consumption, and domestic violence. They reported a pattern where men were seen as stressed, which led to alcohol consumption, which led to domestic violence incidents between themselves and their partners. One participant stated: “Yeah and then sometimes it [alcohol] brings a lot of problems, especially when it comes to going home, brings a lot of problems to homes, to the family. And so that is where the domestic violence come in” (7).

Discussion

Although earlier research has suggested potentially high rates of mental health issues among Belizeans (Ministry of Health and Wellness, 2023; Oladeji et al., Reference Oladeji, Simmons and Baitwabusa2024), this is the first study of its kind to investigate mental health and substance use rates among a group of Belizeans who are not currently undergoing treatment for mental health diagnoses. Our study found high rates of depressive symptoms, suicidal ideation, and anxiety symptoms through quantitative findings that were supported in qualitative interviews. Additionally, low rates of substance use were reported in quantitative findings, yet stated as a critical issue in qualitative interviews. Our findings are in line with those from other LMIC where mental health and substance use concerns are on the rise and of increasing concern for the overall well-being of community members (Alloh et al., Reference Alloh, Regmi, Onche, van Teijlingen and Trenoweth2018; Nadkarni et al., Reference Nadkarni, Gandhi, Bhatia and Velleman2023). Our quantitative findings showed similar or higher rates of depression and anxiety compared to many other LMIC countries. Among study participants, 34% screened positive for major depressive disorder, compared to 14% in Nepal (Kohrt et al., Reference Kohrt, Luitel, Acharya and Jordans2016), 11.5% in Ethiopia (Fekadu et al., Reference Fekadu, Medhin, Selamu, Giorgis, Lund, Alem, Prince and Hanlon2017), and 9% in Mozambique (Cumbe et al., Reference Cumbe, Muanido, Manaca, Fumo, Chiruca, Hicks, de Jesus Mari and Wagenaar2020). In terms of anxiety, 36% of study participants screened positive for generalized anxiety compared to 38% in Lebanon (Sawaya et al., Reference Sawaya, Atoui, Hamadeh, Zeinoun and Nahas2016), 22.8% in Peru (Zhong et al., Reference Zhong, Gelaye, Zaslavsky, Fann, Rondon, Sánchez and Williams2015), and 23.5% in China (Tong et al., Reference Tong, An, McGonigal, S- and Zhou2016). Our findings are particularly concerning given that, using the same measures, the rates of depression and anxiety in general community samples are often higher compared to those reported in primary care settings, where mental health issues are typically reported at higher rates (Park and Zarate, Reference Park and Zarate2019).

Belize faces numerous risk factors for elevated rates of mental health and substance use issues, but Toledo, as the most rural district with the highest poverty levels, presents particularly critical concerns (Statistical Institute of Belize, 2023). While Belize has worked hard to implement supports for mental health and substance use through its PNP program (Killion and Cayetano, Reference Killion and Cayetano2009), our study shows the need for increased financial and human capital to better support the high mental health and substance use concerns of Belizeans, especially in Toledo. Interview participants pointed to financial concerns and family stress as leading causes of mental health challenges. Robust research exists showing the connection between those living in poverty and the detrimental impacts it can have on mental health outcomes (Ridley et al., Reference Ridley, Rao, Schilbach and Patel2020; Guan et al., Reference Guan, Guariglia, Moore, Xu and Al-Janabi2022), often exacerbated by a lack of both economic and mental health resources (Bass, Reference Bass2019). This is evident in Toledo, where the lack of social service infrastructure and governmental support for individuals in poverty and those with mental health concerns hinders Belizeans’ ability to thrive and improve their lives.

Suicidal ideation emerged as a critical mental health concern with 31.9% of survey respondents reporting suicidal thoughts within the last two weeks and 8% reporting suicidal thoughts every day in the previous two weeks. Interview participants initially stated feeling like suicide was not a key concern, but many had anecdotal experiences of hearing about or knowing of a suicide that had occurred in the community. While our quantitative results are based on a single question and more in-depth research is needed to confirm these results, research in other Caribbean and Central American countries has found suicide to be a growing concern (Silverman et al., Reference Silverman, Barnaby, Mishara and Reidenberg2020), leading to the need for an increased understanding of suicide and suicidal ideation among this population.

Our study also offers essential insights into substance use in Toledo, emphasizing the importance of conducting further research to achieve a more comprehensive understanding of this issue. While survey participants reported low levels of substance use, qualitative interviews suggested significant concerns, particularly regarding alcohol consumption. This discrepancy likely stems from stigma and social desirability bias as individuals may have been hesitant to disclose personal substance use in surveys but were more willing to discuss it in relation to others. Similar patterns have been observed in other settings where stigma influences self-reporting on substance use (Yang et al., Reference Yang, Wong, Grivel and Hasin2017). Given the association between alcohol use, masculinity, and socialization in Belize, future research should explore gendered norms and cultural perceptions of substance use. Incorporating alternative data collection methods, such as anonymous self-reports or biological markers, could provide a clearer picture of substance use patterns. Addressing stigma and improving community engagement will be essential in developing effective interventions.

Limitations

This study provides critical baseline data on mental health and substance use in Belize, a valuable contribution given the scarcity of such research in the region. However, the study’s limitations should be acknowledged. Firstly, the focus on participants from Toledo limits the generalizability of the findings to the broader Belizean population as well as to other LMIC and contexts. Future research should look to expand the study to more districts in Belize to provide a fuller understanding of mental health across the country. Additionally, the reliance on univariate quantitative data analysis restricts the ability to explore potential relationships between variables, which could offer deeper insights. The reliance on non-randomized, snowball sampling introduces potential bias, as recruitment was dependent on participant networks rather than probability-based methods. This may have led to overrepresentation of individuals with existing connections to the partner organization or greater trust in healthcare services, while potentially underrepresenting those disengaged from care or experiencing high levels of stigma. Future studies can mitigate potential bias by incorporating additional recruitment strategies, such as randomized community sampling or outreach through multiple, independent community-based organizations to capture a more diverse range of participants. The qualitative interviews, conducted in English rather than participants’ primary languages, may have introduced communication barriers, potentially affecting the ability of participants to fully express their thoughts on the topic. Finally, our study was conducted in 2021 when COVID-19 lockdowns were still in place in Belize which may have impacted participants’ mental health. These limitations suggest the need for future research with a more diverse sample, multivariate analyses, and culturally sensitive methodologies. However, even with these limitations, this study fills important gaps in the literature and helps to establish a baseline understanding of mental health and substance use in Toledo, Belize.

Conclusion and implications

This study highlights the urgent need for increased attention to mental health and substance use concerns in Belize, particularly in rural and underserved areas like Toledo. While Belize has made commendable efforts to improve mental health services—such as the Belize National Mental Health Program, the Mind Health Connect initiative, and Galen University’s recent establishment of a clinical social work program to train more social workers—significant gaps remain in service accessibility and utilization. A key policy implication of our findings is the need for greater financial and human capital investment to support the expansion of mental health services, ensuring that these efforts align with the National Mental Health Policy. Increasing the number of trained mental health professionals, particularly in rural districts, and integrating mental health services into primary care are critical steps toward improving access. However, even if services expand, deep-seated stigma surrounding mental health and therapy remains a significant barrier, making it difficult to engage individuals in treatment. Addressing this requires widespread mental health education and community outreach to normalize seeking care and reduce misconceptions about therapy.

Beyond healthcare, our findings underscore the broader socioeconomic determinants of mental health in Belize. Poverty and financial stress emerged as major contributors to mental health struggles, highlighting the need for stronger governmental welfare support to improve economic conditions and provide social safety nets that can reduce financial strain on individuals and families. Without tackling these structural issues, mental health interventions alone may have limited impact. Further research is needed to investigate specific intervention strategies that can be culturally adapted and effectively implemented in Belize. While increasing access to therapy and psychiatric care is essential, future studies should also explore alternative community-based interventions that account for existing barriers such as stigma, financial hardship, and limited mental health literacy. Given the limited resources currently available, identifying cost-effective, scalable, and community-driven solutions will be key to improving mental health outcomes across the country. By addressing these policy gaps, strengthening economic support systems, and continuing efforts to reduce stigma, Belize can build on its existing progress to create a more comprehensive, accessible, and sustainable mental health care system for all its citizens.

Open peer review

To view the open peer review materials for this article, please visit http://doi.org/10.1017/gmh.2025.10007.

Data availability statement

The data that support the findings of this study are available from the corresponding author, Dr. Jaclyn Kirsch, upon reasonable request.

Acknowledgements

The authors would like to thank the staff and board of Hillside Healthcare International for their assistance and support throughout the project, specifically Alva Gomez, Amira Ack, Jennie Che, Mr. Matthew Nicasio and Dr. Carley Kirsch. Additionally, we thank Dr. Arati Maleku for her assistance and guidance throughout the research process.

Author contribution

Kirsch: conceptualization, funding, investigation, methodology, administration, supervision, validation, writing- original draft, writing-review & edits; Fabbri: formal analysis, validation, writing—review & edits; Kerr: visualization, writing—review & editing; Gomez: conceptualization, investigation, writing—review & editing.

*Contributions listed per CRediT role descriptors.

Financial support

This work was supported by The Ohio State University Office of International Affairs.

Competing interests

Authors report no conflicts of interest.

Ethical statement

This study was approved by the Institutional Review Board at the university within which the study was completed. All participants consented to both participate in the study and for their responses to be included in published work. All data were securely stored on password-protected devices, and access was restricted to authorized research team members to maintain confidentiality.

References

Alloh, FT, Regmi, P, Onche, I, van Teijlingen, E and Trenoweth, S (2018) Mental health in low-and middle income countries (LMICs): Going beyond the need for funding. Health Prospect: Journal of Public Health 17(1), 1217Google Scholar
Bass, J (2019) The relationship between mental health and poverty in low- and middle-income countries. In The Routledge Handbook of International Development, Mental Health and Wellbeing. Routledge. New York, New York.Google Scholar
Belize Ministry of Economic Development (2010) Belize Country Poverty Assessment. Available at https://med.gov.bz/wp-content/uploads/2020/08/CPAExecSummary.pdfGoogle Scholar
Belize Ministry of Health and Wellness (2023) National Mental Health Policy Belize. Available at https://www.who.int/publications/m/item/mental-health-atlas-blz-2020-country-profileGoogle Scholar
Carroll, HA, Hook, K, Perez, OFR, Denckla, C, Vince, CC, Ghebrehiwet, S, Ando, K, Touma, M, Borba, CPC, Fricchione, GL and Henderson, DC (2020) Establishing reliability and validity for mental health screening instruments in resource-constrained settings: Systematic review of the PHQ-9 and key recommendations. Psychiatry Research 291, 113236. https://doi.org/10.1016/j.psychres.2020.113236Google Scholar
Clarke, V and Braun, V (2017) Thematic analysis. The Journal of Positive Psychology 12(3), 297298. https://doi.org/10.1080/17439760.2016.1262613Google Scholar
Creswell, JW (2014) A Concise Introduction to Mixed Methods Research. SAGE Publications. Thousand Oaks, CA.Google Scholar
Cumbe, VFJ, Muanido, A, Manaca, MN, Fumo, H, Chiruca, P, Hicks, L, de Jesus Mari, J and Wagenaar, BH (2020) Validity and item response theory properties of the patient health Questionnaire-9 for primary care depression screening in Mozambique (PHQ-9-MZ). BMC Psychiatry 20(1), 382. https://doi.org/10.1186/s12888-020-02772-0Google Scholar
Estephan, L, Pu, C, Bermudez, S and Waits, A (2023) Burnout, mental health, physical symptoms, and coping behaviors in healthcare workers in Belize amidst COVID-19 pandemic: A nationwide cross-sectional study. International Journal of Social Psychiatry 69(4), 10331042Google Scholar
Evans-Lacko, S, Aguilar-Gaxiola, S, Al-Hamzawi, A, Alonso, J, Benjet, C, Bruffaerts, R, Chiu, WT, Florescu, S, de, GG, Gureje, O, Haro, JM, He, Y, Hu, C, Karam, EG, Kawakami, N, Lee, S, Lund, C, Kovess-Masfety, V, Levinson, D, Navarro-Mateu, F, Pennell, BE, Sampson, NA, Scott, KM, Tachimori, H, ten, HM, Viana, MC, Williams, DR, Wojtyniak, BJ, Zarkov, Z, Kessler, RC, Chatterji, S and Thornicroft, G (2018) Socio-economic variations in the mental health treatment gap for people with anxiety, mood, and substance use disorders: Results from the WHO world mental health (WMH) surveys. Psychological Medicine 48(9), 15601571. https://doi.org/10.1017/S0033291717003336Google Scholar
Fekadu, A, Medhin, G, Selamu, M, Giorgis, TW, Lund, C, Alem, A, Prince, M and Hanlon, C (2017) Recognition of depression by primary care clinicians in rural Ethiopia. BMC Family Practice 18(1), 56. https://doi.org/10.1186/s12875-017-0628-yGoogle Scholar
Fereday, J and Muir-Cochrane, E (2006) Demonstrating rigor using thematic analysis: A hybrid approach of inductive and deductive coding and theme development. International Journal of Qualitative Methods 5(1), 8092. https://doi.org/10.1177/160940690600500107Google Scholar
Fetters, MD, Curry, LA and Creswell, JW (2013) Achieving integration in mixed methods designs—Principles and practices. Health Services Research 48(6pt2), 21342156. https://doi.org/10.1111/1475-6773.12117Google Scholar
Gahman, L, Penados, F and Greenidge, A (2020) Indigenous resurgence, decolonial praxis, alternative futures: The Maya leaders Alliance of southern Belize. Social Movement Studies 19(2), 241248. https://doi.org/10.1080/14742837.2019.1709433Google Scholar
Goodman, LA (2011) Comment: On respondent-driven sampling and snowball sampling in hard-to-reach populations and snowball sampling not in hard-to-reach populations. Sociological Methodology 41(1), 347353. https://doi.org/10.1111/j.1467-9531.2011.01242.xGoogle Scholar
Guan, N, Guariglia, A, Moore, P, Xu, F and Al-Janabi, H (2022) Financial stress and depression in adults: A systematic review. PLoS One 17(2), e0264041. https://doi.org/10.1371/journal.pone.0264041Google Scholar
Hatala, AR and Waldram, JB (2016) The role of sensorial processes in Q’eqchi’ Maya healing: A case study of depression and bereavement. Transcultural Psychiatry 53(1), 6080. https://doi.org/10.1177/1363461515599328Google Scholar
Keynejad, R, Spagnolo, J and Thornicroft, G (2021) WHO mental health gap action programme (mhGAP) intervention guide: Updated systematic review on evidence and impact. Evidence Based Mental Health 24(3). https://doi.org/10.1136/ebmental-2021-300254Google Scholar
Killion, C and Cayetano, C (2009) Making mental health a priority in Belize. Archives of Psychiatric Nursing 23(2), 157165. https://doi.org/10.1016/j.apnu.2008.05.005Google Scholar
Kohrt, BA, Luitel, NP, Acharya, P and Jordans, MJD (2016) Detection of depression in low resource settings: Validation of the patient health questionnaire (PHQ-9) and cultural concepts of distress in Nepal. BMC Psychiatry 16(1), 58. https://doi.org/10.1186/s12888-016-0768-yGoogle Scholar
Kroenke, K, Spitzer, RL and Williams, JBW (2001) The PHQ-9. Journal of General Internal Medicine 16(9), 606613. https://doi.org/10.1046/j.1525-1497.2001.016009606.xGoogle Scholar
Minority Rights Group (2017) Belize. Available at https://minorityrights.org/country/belize/Google Scholar
Nadkarni, A, Gandhi, Y, Bhatia, U and Velleman, R (2023) Closing the treatment gap for alcohol use disorders in low- and middle-income countries. Global Mental Health 10, e3. https://doi.org/10.1017/gmh.2022.57Google Scholar
Oladeji, O, Simmons, J and Baitwabusa, AE (2024) Pattern of presentation and treatment outcomes among patients attending psychotherapy Services in a Primary Health Care Centre in Belize. Journal of Advances in Medicine and Medical Research 36(6), 118132. https://doi.org/10.9734/jammr/2024/v36i65457Google Scholar
Pan American Health Organization (2013) WHO-AIMS: Report on Mental Health Symstems in Latin America and the Caribbean. Washington DC. Available at https://www3.paho.org/hq/dmdocuments/2013/ENG-WHOAIMSREG-(For-Web-Apr-2013).pdfGoogle Scholar
Pan American Health Organization (2021, October 18) Building the Punta Gorda Community Hospital in Belize to Become Disaster-Resilient and Climate-Friendly. Available at https://www.paho.org/en/stories/building-punta-gorda-community-hospital-belize-become-disaster-resilient-and-climateGoogle Scholar
Park, LT and Zarate, CA (2019) Depression in the primary care setting. The New England Journal of Medicine 380(23), 22792280. https://doi.org/10.1056/NEJMc1903259Google Scholar
Plummer, F, Manea, L, Trepel, D and McMillan, D (2016) Screening for anxiety disorders with the GAD-7 and GAD-2: A systematic review and diagnostic metaanalysis. General Hospital Psychiatry 39, 2431. https://doi.org/10.1016/j.genhosppsych.2015.11.005Google Scholar
Reid, S, Downes, E and Khenti, A (2015) The anatomy of a successful Caribbean substance abuse training programme. WIMJ Open 2(1), 4145. https://doi.org/10.7727/wimjopen.2014.260Google Scholar
Rich, GJ, Gentle-Genitty, C and Estrada, C (2022) Psychology in Belize. In Rich, GJ and Ramkumar, NA (eds), Psychology in Oceania and the Caribbean. Cham: Springer International Publishing, pp. 283294. https://doi.org/10.1007/978-3-030-87763-7_20.Google Scholar
Ridley, M, Rao, G, Schilbach, F and Patel, V (2020) Poverty, depression, and anxiety: Causal evidence and mechanisms. Science 370(6522), eaay0214. https://doi.org/10.1126/science.aay0214Google Scholar
Sawaya, H, Atoui, M, Hamadeh, A, Zeinoun, P and Nahas, Z (2016) Adaptation and initial validation of the patient health questionnaire – 9 (PHQ-9) and the generalized anxiety disorder – 7 questionnaire (GAD-7) in an Arabic speaking Lebanese psychiatric outpatient sample. Psychiatry Research 239, 245252. https://doi.org/10.1016/j.psychres.2016.03.030Google Scholar
Shoman, A (2010) Belize’s Independence and Decolonization in Latin America: Guatemala, Britain, and the UN. Springer. New York, New York.Google Scholar
Silverman, MM, Barnaby, L, Mishara, BL and Reidenberg, DJ (2020) Suicide prevention in the Americas. Crisis: The Journal of Crisis Intervention and Suicide Prevention 41(Suppl 1), S30S52. https://doi.org/10.1027/0227-5910/a000667Google Scholar
Spitzer, RL, Kroenke, K, Williams, JBW and Löwe, B (2006) A brief measure for assessing generalized anxiety disorder: The GAD-7. Archives of Internal Medicine 166(10), 10921097. https://doi.org/10.1001/archinte.166.10.1092Google Scholar
Statistical Institute of Belize (2023) Multidimensional poverty index to complement monetary poverty measurement in Belize. Available at https://sib.org.bz/multidimensional-poverty-index-release/Google Scholar
Sweetland, AC, Oquendo, MA, Sidat, M, Santos, PF, Vermund, SH, Duarte, CS, Arbuckle, M and Wainberg, ML (2014) Closing the mental health gap in low-income settings by building research capacity: Perspectives from Mozambique. Annals of Global Health 80(2), 126133. https://doi.org/10.1016/j.aogh.2014.04.014Google Scholar
Tong, X, An, D, McGonigal, A, S-, P P and Zhou, D (2016) Validation of the generalized anxiety Disorder-7 (GAD-7) among Chinese people with epilepsy. Epilepsy Research 120, 3136. https://doi.org/10.1016/j.eplepsyres.2015.11.019Google Scholar
Wallerstein, N, Duran, B, Oetzel, JG and Minkler, M (2017) Community-Based Participatory Research for Health: Advancing Social and Health Equity. John Wiley & Sons. Hoboken, NJ.Google Scholar
Whitehorne-Smith, P, Burns, S, Milbourn, B, Abel, W and Martin, R (2020) Cross-sectional mixed-methods study protocol exploring the enablers and barriers for people with severe and enduring mental illness in Jamaica when accessing healthcare for chronic physical illness. BMJ Open 10(8), e038245. https://doi.org/10.1136/bmjopen-2020-038245Google Scholar
World Bank (2022) Population, total- Belize. Available at https://data.worldbank.org/indicator/SP.POP.TOTL?locations=BZGoogle Scholar
World Health Organization (2009) Belize: Prioritizing Mental Health Services in the Community. Available at https://www3.paho.org/hq/dmdocuments/2009/Belize-Country-Summary-March-2009.pdfGoogle Scholar
Yang, L, Wong, LY, Grivel, MM and Hasin, DS (2017) Stigma and substance use disorders: An international phenomenon. Current Opinion in Psychiatry 30(5), 378388. https://doi.org/10.1097/YCO.0000000000000351Google Scholar
Zhong, Q-Y, Gelaye, B, Zaslavsky, AM, Fann, JR, Rondon, MB, Sánchez, SE and Williams, MA (2015) Diagnostic validity of the generalized anxiety disorder – 7 (GAD-7) among pregnant women. PLoS One 10(4), e0125096. https://doi.org/10.1371/journal.pone.0125096Google Scholar
Figure 0

Table 1. Demographic characteristics of study participants (N = 173)

Figure 1

Table 2. Depression and suicide (PHQ-9)

Figure 2

Table 3. Anxiety (GAD-7)

Figure 3

Table 4. Substance use

Author comment: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR1

Comments

Dear Drs. Bass and Chibanda,

On behalf of my research team, I am submitting our manuscript “Current State of Mental Health and Substance Use in Toledo, Belize: A Mixed Methods Study” for exclusive consideration for publication as an article in Global Mental Health. Our study uses exploratory mixed methods approaches to report on current rates of mental health and substance use in rural Belize. While we acknowledge the use of univariant analysis of a non-randomized sample within our quantitative data, we believe there is gap in the literature reporting on mental health outcomes among Belizeans and that this study is imperative for future research within this context. We additionally are slightly over the word limit of your journal but as a mixed methods article believe this is warranted. We previously submitted this manuscript to Global Mental Health, received a rejection but were encouraged to resubmit with changes made to the aims of the paper which has been done. All the authors of the manuscript declare that there are no conflicts of interest associated with this manuscript.

Thank you for your consideration of our work! Please address all correspondence concerning this manuscript to me at the address below.

Sincerely,

Jaclyn Kirsch, PhD, MSW, MPH, LISW-S

Assistant Professor

University of Texas at Arlington,

School of Social Work

jaclyn.kirsch@uta.edu

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR2

Conflict of interest statement

Reviewer declares none.

Comments

The title accurately reflects the content of the paper, indicating a focus on mental health and substance use in Toledo, Belize, using a mixed methods approach. It is advised to consider the following suggestions:

1. Authors should succinctly summarize the summary, highlighting key findings and their implications, while clearly presenting goals, methods, and findings to engage the reader.

2. The introduction provides a good overview of mental health and substance use issues in low - and middle-income countries and the specific situation in Belize Toledo. However, the author should clarify the research gaps covered by the study and strengthen the links between global mental health issues and specific challenges faced in Belize, particularly in rural Toledo.

3. In the methodology section, the use of a community-based participatory research (CBPR) approach and an exploratory sequential hybrid approach to design is commendable. The author should elaborate on the rationale behind choosing a mixed methods approach and how it added value to the study compared to using a single method? The authors should provide more details on how the CBPR approach affects participant participation and data collection, and further elaborate on the limitations of snowball sampling and how to mitigate potential bias.

4. The results are clearly presented with tables supporting the text description. It is recommended to summarize the main findings in the text to supplement the table for readers who may not focus on the numerical data. Authors can also ensure a consistent integration of qualitative and quantitative research findings to provide a comprehensive understanding.

5. The discussion effectively linked the findings to broader issues in mental health and substance use in low - and middle-income countries. The authors should discuss the implications of the findings more broadly, especially in terms of policy and intervention strategies. In addition, authors need to compare the findings with other relevant studies to put their contributions in context.

6. The conclusions highlight the need for further research and policy development. It is recommended to strengthen the call to action by explicitly suggesting specific policy or program reforms, and to suggest avenues for future research that may build on the findings of this study.

7. The references are relevant and up-to-date, providing a strong foundation for the study. However, ensure all citations are properly formatted according to the journal’s guidelines.

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR3

Conflict of interest statement

I have no competing interests.

Comments

Current State of Mental Health and Substance Use in Toledo, Belize: A Mixed Methods Study

Abstract

This is a well written abstract.

Background/rationale

It is written well. However the section title is missing.

Methods

The methodology section is designed well and appropriate for the study questions and aims

Results

The results are presented clearly.

Discussion

The discussion relates well to the study aims, methods and findings.

Conclusion

This is a well written manuscript. It represents important findings on mental health and substance use patterns in Belize. It forms an important foundation for future studies.

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR4

Conflict of interest statement

Reviewer declares none.

Comments

The manuscript addresses a substantial gap in mental health and substance use research in Belize. This research further focuses on the marginalized community in the Toledo district. The mixed-methods approach provides quantitative and qualitative insights, helping build a strong foundation for mental health data.

The manuscript’s exploration of depression, anxiety, suicidal ideation, and substance use provides a comprehensive understanding of mental health challenges in the community. The focus (impact statement) on the need for more research, advocacy, and policy implementation highlights the study’s contribution to global mental health.

Some sections (Methods and Discussion) include language that could be simplified for better readability. (i.e., the explanation of coding processes in the qualitative analysis may be condensed without losing detail).

The difference between the quantitative and qualitative findings regarding substance use is worth exploring further. Examining further how stigma might play a role in underreporting in the quantitative data could add depth to the findings and provide meaningful cultural insights.

Recommendations:

The abstract provides a comprehensive summary of the study. Including a sentence on the policy implications for Belize’s mental health infrastructure would further enhance its impact.

I would recommend adding more context about recent efforts to improve mental health services overall in Belize. While it’s clear that Toledo remains underserved, including an overview of the developments or progress that is happening could provide valuable context and help frame the challenges in the district more effectively (i.e., Belize National Mental Health Program (Ministry of Health and Wellness), Mind Health Connect, Galen University MSW program (clinical), School Counselor’s Association, etc).

The discussion section can be strengthened by referencing similar studies in neighboring LMICs or the broader Caribbean region to position the findings within a global context.

The manuscript highlights the need for further studies but could provide more specific recommendations, such as exploring, for example, the role of traditional healing practices in mental health interventions.

Overall, this manuscript makes a valuable contribution to the field of global mental health, particularly by providing baseline data for an underrepresented country of Belize.

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR5

Conflict of interest statement

No

Comments

- you used n=163 for a survey and only 10 for interviews why the sample size is much different? If you want to use mixed methods you need a reliable sample size in both groups, provide your logic with reference.

The abstract and scaling procedure looks good.

- Please use the sampling design of the study instead of the design

- you used SPSS 27, please provide your data and code as a supplement file to reproduce the results

- Review the results again and correct if you find any inconsistencies

- and strength of your work.

- at the end of the discussion you need to provide some recommendations. The discussion is not well written overall. revise and improve it.

I made generic comments about the results. I Want to review it again after reproducing the results of getting data and code. Thank you.

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR6

Conflict of interest statement

No conflict of interest

Comments

This is an essential work in this area and context. I would like to congratulate the authors for undertaking this critical study. The comments and reasons for the decision are provided in detail for the improvement.

Section 1: Introduction

•Line 12-15: The reference could be updated to a more recent one, rather than (Sweetland et al., 2014), which is nearly a decade old.

•The introduction could be more concise and focused on presenting a strong case for support. The excessive word count in the introduction might be better utilized in the methods or results sections.

Example: The information about Belize and Toledo could be more concise, and relevant references should be included. While this information is important for making a strong case for support, it could be condensed.

•Page 4-Line 19-21: It required a reference

•Repetition of information could be reduced

•Page 5: line “While these data are informative, they do not provide an accurate depiction of mental health and substance use across the entire population due to the treatment gap between those living with mental illness and substance use disorders and those who seek treatment in LMIC (Evans-Lacko et al. 2018)”: what are the factors for treatment gap in this context and is there any data discuss about the treatment gap in this particular context?

•Page 5: Line “This limited information regarding mental health and substance use in the country leads to limited understanding of needs.” At the same time, there were data documented in the Belize Health information system regarding the diagnosis of people who sought mental health care. This report included the rates of mental health conditions and mentioned substance use but not the percentage of SUDs. It is recommended to check the original data/survey results and record the reasons for non-documentation of substance use disorders.

Overall, the introduction could be more focused by reducing some of the information. It could begin by providing a broader perspective, then narrow down to the mental health prevalence and challenges within the Belize context. The introduction should also highlight the literature gap, the need for this specific study, and how the study will address that gap. The background information should effectively build a strong case for supporting the study.

Section 2. Methods

Design

•The argument for the community participatory approach concept is unclear as the participatory approach in research has different dimensions such as engagement, involvement and participation with the stakeholder. The current explanation leads to collaboration rather than using a community participatory approach.

Example: Where the stakeholders other than collaborating organisations involved in planning and co-designing? If that includes only data collection from the community samples, then that would be just a ‘participation’ in the research, which is typical for all the research with the human population.

•The reason for choosing only the staff of the organisation for the qualitative interviews needs to be justified considering the research question as it explores the mental health and substance use-related issues of the community participants. The limitation of this approach would be that it only considers the ‘Patient Reported Outcome Measures’ and omits ‘Patient Experienced Outcome Measures’ along with it, however, attempting a data triangulation!

•The sample size calculation for the quantitative phase was not clearly specified, which further limits the generalizability of the findings. The question of whether these samples accurately represent the population remains uncertain.

Example: Do these findings represent the particular community population? Since the study is a kind of prevalence type, a small number of samples may overrepresent the findings.

•Information regarding ethical approval needs further clarification, as it is important to understand details about the ethical review board and how data management and protection were handled, especially since the study used both online and face-to-face data collection methods.

•A brief about the partnering organisation (in one or two sentences) in the background would be useful for the readers to get an idea well and necessary as they were involved throughout the research and recruited samples for the qualitative phase from there.

•Qualitative: The inclusion and exclusion criteria have not been mentioned in the qualitative phase, including who this staff was, their background, and their experience, as they were asked for information related to their observations of mental health issues. If the staff are mental health professionals, they would have a better idea than someone from non-mental health or admin staff!

•Further, who collected data, whether they were trained, the medium of interviews, why an online platform etc, is essential information in this section and sample size.

•Quantitative: “All scales were reviewed with community partners to assess questions' applicability to the Belizean cultural context. No changes were suggested, and all scales and questions were acceptable.” This was unclear and convincing during the process. Who were these partners other than the one collaborating organisation?

•The staff were trained to collect data and this is a good practice. However, it is essential to mention the mental health background of the staff who collected the data as they are assessing depression and anxiety among the participants.

•“Survey data was collected via three staff members from the partner healthcare clinic.” This again indicates more information about the partner organisation as the readers do not understand the settings, which would limit them from understanding the study process.

•The study employed purposeful/convenience sampling along with the snowball sampling technique. Why is snowball sampling being used as a sampling method? Is the sample drawn from the community or specifically from individuals with various mental health issues? This aspect needs clarification, as it highlights the importance of having clear inclusion and exclusion criteria for participants or defining who the participants were in this phase.

•Information on PHQ 9 and GAD 7: the information could be reduced by giving the reason for choosing this scale and citing a reference.

•The reason for choosing the assessment tool for substance use is not clear

Data analysis

• Qualitative analysis: The framework used for the qualitative analysis is suitable and appropriate

• Quantitative analysis is key, and the analysis was not clearly mentioned (for example: Is it descriptive by using mean and SD or frequency and percentage)

• Triangulation of data: The study collected both qualitative and quantitative data and missing information related to the plans for the triangulation of data.

Section 3. Results

Quantitative:

1. The socio-demographic details need to be more elaborated, including information on socioeconomic status, education, employment, and other relevant factors. Since the study aims to assess mental health and substance use issues among participants from a rural community in Belize, these details are essential.

2. Denominator is important, out of how many of these findings? Breaking of findings in each of these conditions based on gender and other socio-economic variables is highly recommended to get more clarity

3. Data related to suicidality/suicidal ideas: PHQ 9 scale’s 9th question is related to suicidality. Do the authors use any other scales?

4. The association between socio-demographics and prevalence needs to be explored.

5. The triangulation of qualitative and quantitative needed to improve further,

Example: Qualitative finding ““There is a lot of people that don’t have jobs, they don’t have as good of income to provide for the family all these stress, things like that, people get depressed” needed to be triangulated with quantitative socio-demographic findings and that information was not mentioned in the results.

Qualitative

The facilitators and barriers to mental healthcare have not been reported in the results and this was one of the objectives of the qualitative interview with the staff.

The significant drawbacks of the findings are,

1. The fundamental question of whether these samples represent the larger community as a sample calculation has not been done.

2. Why use a mixed method instead of survey methods and only common mental disorders and substance use?

3. Patient Reported outcome measures and staff experience outcome measures! Instead, the generalisability would have been more accurate if the qualitative data had been collected from the same participants along with the quantitative data and staff could be additional to ensure the quality of findings.

Section 4. Discussion

• Discussion needed to be focused on the key findings.

Section 5. References

• Online/website information required date of access

• Incomplete references

Example: Bolland ON (2003) no place of publication and chapter or page!

Please check the submission guidelines for the references

Recommendation: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR7

Comments

Thank you for submitting your manuscript to Global Mental Health. We have received comments from 5 reviewers who all provided similar feedback. As you will note in their comments, there is some information missing from the manuscript, particularly in the methods section, that we request the authors add to improve clarity and reproducibility. The reviewers have also provided some suggestions for improving the analysis and results, including the triangulation of qualitative and quantitative information. We hope you find these comments useful and consider revising your manuscript accordingly.

Decision: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R0/PR8

Comments

No accompanying comment.

Author comment: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R1/PR9

Comments

Dear Drs. Bass and Chibanda,

On behalf of my research team, I am re-submitting our manuscript “Current State of Mental Health and Substance Use in Toledo, Belize: A Mixed Methods Study” for exclusive consideration for publication as an article in Global Mental Health. Our study uses exploratory mixed methods approaches to report on current rates of mental health and substance use in rural Belize. While we acknowledge the use of univariant analysis of a non-randomized sample within our quantitative data, we believe there is gap in the literature reporting on mental health outcomes among Belizeans and that this study is imperative for future research within this context. We additionally are slightly over the word limit of your journal but as a mixed methods article believe this is warranted. We appreciate the opportunity to make a revision to our manuscript and appreciate the valuable comments provided by all the reviewers. We have addressed them all point by point, as well as have all our edits track changed throughout the document for reviewers to easily view our changes. All the authors of the manuscript declare that there are no conflicts of interest associated with this manuscript.

Thank you for your consideration of our work! Please address all correspondence concerning this manuscript to me at the address below.

Sincerely,

Jaclyn Kirsch, PhD, MSW, MPH, LISW-S

Assistant Professor

University of Texas at Arlington,

School of Social Work

jaclyn.kirsch@uta.edu

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R1/PR10

Conflict of interest statement

Reviewer declares none.

Comments

Dear Editor,

I greatly appreciate the opportunity to evaluate this revised manuscript. I have thoroughly examined the updated manuscript, which incorporates the author(s) responses and modifications to the document. I have no further revisions.

Thanks.

Kind regards,

Review: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R1/PR11

Conflict of interest statement

Reviewer declares none.

Comments

The revised manuscript has effectively incorporated all previous recommendations, resulting in a clearer, more comprehensive, and well-contextualized study on mental health and substance use in Belize. The improvements in readability, particularly in the Methods and Discussion sections, enhance accessibility without compromising detail. The refined explanation of the qualitative coding process is now more concise, and the discussion of stigma’s role in substance use reporting adds important cultural nuance.

Notably, the manuscript now provides a stronger policy connection, with the abstract explicitly addressing the implications for Belize’s mental health infrastructure. The inclusion of recent mental health initiatives, such as the Belize National Mental Health Program and Mind Health Connect, strengthens the discussion by situating the study within ongoing national efforts. Additionally, linking the findings to broader global and regional research enhances the study’s relevance beyond the Belizean context.

The manuscript also now offers more concrete recommendations for future research, including the exploration of traditional healing practices in mental health interventions. These additions further contribute to the study’s impact on both research and policy.

Given these thoughtful revisions and strengthened contributions, I recommend acceptance of the manuscript. Congratulations to the authors on this important and impactful work.

Recommendation: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R1/PR12

Comments

Congratulations to the authors on an excellent revision of the manuscript. Both the reviewers and I appreciate the thoughtful and substantial improvements made, and we are pleased to recommend the manuscript for publication.

Decision: Current state of mental health and substance use in Toledo, Belize: A mixed methods study — R1/PR13

Comments

No accompanying comment.