Hostname: page-component-745bb68f8f-cphqk Total loading time: 0 Render date: 2025-01-11T14:53:35.205Z Has data issue: false hasContentIssue false
  • English
  • Français

Mode of Action of Substituted Uracil Herbicides

Published online by Cambridge University Press:  12 June 2017

J. L. Hilton ,
T. J. Monaco ,
D. E. Moreland  and
W. A. Gentner
J. L. Hilton
Affiliation:
Crops Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland
T. J. Monaco
Affiliation:
Crops Research Division, Agricultural Research Service, United States Department of Agriculture, Crop Science Department, North Carolina State College, Raleigh, North Carolina
D. E. Moreland
Affiliation:
Crops Research Division, Agricultural Research Service, United States Department of Agriculture, Crop Science Department, North Carolina State College, Raleigh, North Carolina
W. A. Gentner
Affiliation:
Crops Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland
Get access

Abstract

Results of studies with microorganisms suggest that 5-bromo-3-isopropyl-6-methyluracil (isocil) does not interfere appreciably with pyrimidine metabolism. Instead the uracil herbicides studied appear to act in higher plants as inhibitors of photosynthesis. Strong inhibition of the Hill reaction of isolated chloroplasts by substituted uracils was noted (I50 of 2.7 × 10−6 M for isocil). Exogenously supplied carbohydrates partially nullified toxicity symptoms in intact barley plants growing in the presence of inhibitory concentrations of isocil.

Type
Research Article
Information
Weeds , Volume 12 , Issue 2 , April 1964 , pp. 129 - 131
Copyright
Copyright © 1964 Weed Science Society of America 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Literature Cited

1. Bucha, H. C., Cupsry, W. E., Harrod, J. E., Loux, H. M., and Ellis, L. M. 1962. Substituted uracil herbicides. Science 137:537–538.CrossRefGoogle ScholarPubMed
2. Fairley, J. L., and Adams, A. B. 1961. Arginine and pyrimidine biogenesis in Neurospora . Science 134:471–472.Google Scholar
3. Gentner, W. A. 1963. 1962 Field evaluation of chemicals for their herbicidal properties. USDA-ARS-CR-2-63. 78 pp.Google Scholar
4. Gentner, W. A. and Hilton, J. L. 1960. Effect of sucrose on the toxicity of several phenylurea herbicides to barley. Weeds 8:413–417.Google Scholar
5. Hilton, J. L. 1962. Riboflavin nullification of inhibitory actions of 3-amino-1,2,4-triazole on seedling growth. Plant Physiol. 37:238–244.Google Scholar
6. Hilton, J. L., Jansen, L. L. and Gentner, W. A. 1958. Betaalanine protection of yeast growth against the inhibitory action of several chlorinated aliphatic acid herbicides. Plant Physiol. 33:43–45.Google Scholar
7. Mitchell, H. K., and Houlahan, M. B. 1946. Adenine-requiring mutants of Neurospora crassa . Fed. Proc. 5:370–375.Google Scholar
8. Moreland, D. E., Gentner, W. A., Hilton, J. L., and Hill, K. L. 1959. Studies on the mechanism of herbicidal action of 2-chloro-4,6-bis(ethylamino)-s-triazine. Plant Physiol. 34:432–435.CrossRefGoogle ScholarPubMed
9. Hilton, J. L. and Hill, K. L. 1959. The action of alkyl N-phenylcarbamates on the photolytic activity of isolated chloroplasts. J. Agr. and Food Chem. 7:832–837.Google Scholar
10. Hilton, J. L. and Hill, K. L. 1962. Interference of herbicides with the Hill reaction of isolated chloroplasts. Weeds 10:229–236.Google Scholar
11. Hilton, J. L. and Hill, K. L. 1963. Inhibition of photochemical activity of isolated chloroplasts by acylanilides. Weeds 11:55–60.Google Scholar
12. Hilton, J. L. and Hill, K. L. 1963. Inhibition of photochemical activity of isolated chloroplasts by polycyclic ureas. Weeds 11:284–287.Google Scholar
13. Sweetser, P. E., and Todd, C. W. 1961. The effect of monuron on oxygen liberation in photosynthesis. Biochem. Biophys. Acta. 51:504–508.Google Scholar
14. Van Oorschot, J. L. P., and Hilton, J. L. 1963. Effects of chloro substitutions on aliphatic acid inhibitors of pantothenate metabolism in Escherichia coli . Arch. Biochem. Biophys. 100:289–294.Google Scholar