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Neuroendocrine tests of monoamine function in man: a review of basic theory and its application to the study of depressive illness

Published online by Cambridge University Press:  09 July 2009

S. A. Checkley
S. A. Checkley*
Affiliation:
Institute of Psychiatry, London
*
1Address for correspondence: Dr S. A. Checkley, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF.
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Synopsis

Neuroendocrine tests are now available for studying monoamine function in the brains of patients with mental illness. Great care is required in the selection of drugs which act upon specific monoamine receptors to produce specific hormonal responses. Equal care is required in the control of biological variables which may influence hormonal release.

Recently reported neuroendocrine studies of depressive illness are assessed in these terms. The results of these studies support the hypothesis that there is defective noradrenergic function in the brains of some patients with depressive illness.

Type
Research Article
Information
Psychological Medicine , Volume 10 , Issue 1 , February 1980 , pp. 35 - 53
Copyright
Copyright © Cambridge University Press 1980

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