Hostname: page-component-745bb68f8f-f46jp Total loading time: 0 Render date: 2025-01-25T20:04:03.953Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies on the susceptibility of the guinea-pig to infection with Schistosoma spindale Montgomery, 1906*

Published online by Cambridge University Press:  06 April 2009

S. C. Dutt
S. C. Dutt
Affiliation:
Division of Parasitology, Indian Veterinary Research Institute, Izatnagar, India
Get access Rights & Permissions [Opens in a new window]

Extract

Studies on the susceptibility of the guinea-pig to infection with Schistosoma spindale Montgomery are reported.

Of twenty-two guinea-pigs, examined 33–153 days after exposures to 8000–50,000 cercariae of S. spindale, seventeen furnished conclusive evidence of the development of the female schistosome and two furnished inconclusive evidence. The male S. spindale developed in all the animals.

The female schistosomes attained maturity in 48 days or more and laid viable ova which could be detected in the liver, intestinal wall and lungs, but not in faeces.

The pathological lesions caused by the parasite consisted of thrombosis in the liver and lungs due to adult worms and pseudotubercles in the liver and nodules in the intestinal wall due to the eggs.

The guinea-pig shows varying degrees of individual susceptibility to infection with S. spindale and is an unsuitable host for the parasite, more especially for the female schistosome.

Type
Research Article
Information
Parasitology , Volume 52 , Issue 1-2 , May 1962 , pp. 199 - 206
Copyright
Copyright © Cambridge University Press 1962

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Bang, F. B. & Hairston, N. G. (1946). Studies on schistosomiasis japonica. IV. Chemotherapy of experimental schistosomiasis japonica. Amer. J. Hyg. 44, 348–66.Google Scholar
Dutt, S. C. & Srivastava, H. D. (1962). Studies on the morphology and life history of the mammalian blood-fluke Orientobilharzia dattai (Dutt & Srivastava, 1952) Dutt & Srivastava, 1955. Part III. Definitive host specificity. Indian J. Vet. Sci. (in the Press).Google Scholar
Editor, Lancet (1930), cited by Girges, R. (1934). Schistosomiasis (Bilharziasis), 529 pp. London: John Bale, Sons and Danielsson.Google Scholar
Fairley, N. H. & Mackie, F. P. (1930). Studies in Schistosoma spindale. Part III. The experimental pathology in the goat with special reference to verminous phlebitis. Indian Med. Res. Mem. 17, 17–51.Google Scholar
Fairley, N. H., Mackie, F. P. & Jesudasan, F. (1930). Studies in Schistosoma spindale. Part V. The guinea-pig as a host of male schistosomes. Indian Med. Res. Mem. 17, 61–2.Google Scholar
Leiper, R. T. (1915). Report on the results of the Bilharzia mission to Egypt. Part I. Transmission. J. R. Army Med. Cps, 25, 1–55.Google Scholar
Liston, W. G. & Soparkar, M. B. (1918). Bilharziasis among animals in India. The life cycle of Schistosoma spindalis. Indian J. Med. Res. Calcutta, 5, 567–9.Google Scholar
Meleney, H. E., Sandground, J. H., Moore, D. V., Most, H. & Carney, B. H. (1953). The histopathology of experimental schistosomiasis. II. Bisexual infections with S. mansoni, S. japonicum, and S. haematobium. Amer. J. Trop. Med. Hyg. 2, 883–913.CrossRefGoogle Scholar
Moore, D. V. & Meleney, H. E. (1954). Comparative susceptibility of common laboratory animals to experimental infection with Schistosoma haematobium. J. Parasit. 40, 392–7.CrossRefGoogle ScholarPubMed
Moore, D. V., Yolles, T. K. & Meleney, H. E. (1949). A comparison of common laboratory animals as experimental hosts for Schistosoma mansoni. J. Parasit. 35, 156–70.CrossRefGoogle ScholarPubMed
Rao, M. A. N. (1934). A comparative study of Schistosoma spindalis Montgomery, 1906, and Schistosoma nasalis, n.sp. Indian J. Vet. Sci. 4, 1–28.Google Scholar
Srivastava, H. D. & Dutt, S. C. (1961). Studies on Schistosoma indicum Montgomery, 1906. I.C.A.R., Res. Bull, (in the Press).Google Scholar
Standen, O. D. (1949). Experimental schistosomiasis. II. Maintenance of Schistosoma mansoni in the laboratory, with some notes on experimental infection with S. haematobium. Ann. Trop. Med. Parasit. 43, 268–83.CrossRefGoogle Scholar
Stirewalt, M. A., Kuntz, R. E. & Evans, A. S. (1951). The relative susceptibilities of the commonly-used laboratory mammals to infection by Schistosoma mansoni. Amer. J. Trop. Med. 31, 57–81.CrossRefGoogle ScholarPubMed