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Gastrointestinal mucus, a medium for survival and for elimination of parasitic nematodes and protozoa

Published online by Cambridge University Press:  23 August 2011

H. R. P. Miller
H. R. P. Miller
Affiliation:
Moredun Research Institute, 408 Gilmerton Road, Edinburgh EH17 7JH
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Mucus is a sticky visco-elastic material which coats all mucosal surfaces. Florey, in 1955, noted the following three functions for gastrointestinal mucus: protection of the underlying mucosa from chemical and physical injury, lubrication of the mucosal surface to facilitate passage of luminal contents, and removal of parasites by binding and entrapment. In the 31 years since Florey's review, detailed analyses of the composition of mucus and of the biochemistry of mucin glycoproteins, as well as measurements of the physical properties of mucus from different organs and sites have yielded information at the molecular level which provide additional support for his views on its function (Allen, 1981; Forstner, Wesley & Forstner, 1982).

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Research Article
Information
Parasitology , Volume 94 , supplement S1: Symposia of the British Society for Parasitology Volume 24 Pathophysiological responses to parasites , January 1987 , pp. S77 - S100
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Copyright © Cambridge University Press 1987

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