Hostname: page-component-745bb68f8f-kw2vx Total loading time: 0 Render date: 2025-01-28T23:27:28.587Z Has data issue: false hasContentIssue false
  • English
  • Français

Selective Biofunctionalization all-(111) Surface Silicon Nanowires

Published online by Cambridge University Press:  31 January 2011

Muhammad Masood ,
Songuye Chen ,
Edwin T Carlen  and
Albert Van den Berg
Muhammad Masood
Affiliation:
m.n.masood@ewi.utwente.nl
Songuye Chen
Affiliation:
s.chen@ewi.utwente.nl, Mesa+ Institute University of Twente, Electrical, Computer and Mathematics, Enschede, Netherlands
Edwin T Carlen
Affiliation:
e.t.carlen@ewi.utwente.nl, Mesa+ Institute University of Twente, Electrical, Computer and Mathematics, Enschede, Netherlands
Albert Van den Berg
Affiliation:
a.vandenberg@utwente.nl, Mesa+ Institute University of Twente, Electrical, Computer and Mathematics, Enschede, Netherlands
Get access

Abstract

Selective biomolecular functionalization of our all-(111) surface silicon nanowire (SiNW) biosensors using covalently linked alkyl- monolayers is demonstrated. Monolayers were made using a commercially available six member carbon precursor N-(5-Hexynyl) phthalimide and UV based hydrosylilation reaction. Contact angle and x-ray photoelectron spectroscopy (XPS) measurements were used to characterize the monolayer at different stages on planar Si (111) samples. Terminal amine groups on the monolayer surface were used for further conjugation with (+)-Biotin N-hydroxysuccinimide ester after deprotection of the phthalimide group with a methylamine solution. Selective biofunctionalization was demonstrated by reacting the SiNW-monolayer-biotin surface with 5 nm gold nanoparticles conjugated with streptavidin and subsequent high resolution scanning electron microscopy imaging.

Keywords

nanoscalex-ray photoelectron spectroscopy (XPS)biological
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1236: Symposium SS – Biosurfaces and Biointerfaces , 2009 , 1236-SS08-22
Copyright
Copyright © Materials Research Society 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Cui, Y. Wei, Q.Q. Park, H. K. and Lieber, C.M. Science 293, 1289 (2001).Google Scholar
2 Bunimovich, Y.L. Shin, Y. S. Yeo, W. Amori, M. Kwong, G. and Heath, J.R. J. Am. Chem. Soc. 128, 16323 (2006).Google Scholar
3 Gao, Z.Q. Agarwal, A. Trigg, A.D. Singh, N. Fang, C. Tung, C.H. Fan, Y. Buddharaju, K.D. Kong, J.M. Anal. Chem. 79, 3291 (2007).Google Scholar
4 Patolsky, F. and Lieber, C.M. Mater. Today April (2005).Google Scholar
5 Wanekaya, A.K. Chen, W. Myung, N.V. and Mulchandani, A. Electroanal. 18, 533 (2006).Google Scholar
6 Voort, D. van der, McNeil, C.A. Renneberg, R. Korf, J. Hermens, W.T. Glatz, J.F.C. Sensor Actuat B-Chem. 105, 50 (2005).Google Scholar
7 Bunimovich, Y.L. Ge, G. Beverly, K.C. Ries, R.S. Hood, L. and Heath, J.R. Langmuir, 20, 10630 (2004).Google Scholar
8 Weldon, M.K. Queeney, K.T. Eng, J. Jr. , Raghavachari, K. Chabal, Y.J. Surf. Sci. 500, 859 (2002).Google Scholar
9 Chen, S. Bomer, J.G. Wiel, W.G.Van der, Carlen, E.T. Berg, A. Van den, ACS Nano 3 3485 (2009).Google Scholar
10 Buriak, J.M. Chem. Rev. 102, 1272 (2002).Google Scholar
11 Bent, S.F. Surf. Sci. 500, 879 (2002).Google Scholar
12 Puniredd, S.R. Assad, O. Haick, H. J. Am. Chem. Soc. 130, 13727 (2008).Google Scholar
13 Zuilhof, H. and Sudholter, E.J.R. Adv. Mater. 12, 1457 (2000).Google Scholar
14 Ciero, R.L. and Chidsey, C.E.D. Langmuir 18, 305 (2002).Google Scholar