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DNA Templating of Ethylene-Oxide-Coated Nanoclusters

Published online by Cambridge University Press:  11 February 2011

S. Jhaveri ,
E. E. Foos ,
M. G. Ancona ,
A. W. Snow ,
M. E. Twigg ,
E. Chang ,
K. Pilobello ,
E. Goldman  and
D. Lowy
S. Jhaveri
Affiliation:
NRC Postdoctoral Associate
E. E. Foos
Affiliation:
Naval Research Laboratory, Washington, DC 20375
M. G. Ancona
Affiliation:
Naval Research Laboratory, Washington, DC 20375
A. W. Snow
Affiliation:
Naval Research Laboratory, Washington, DC 20375
M. E. Twigg
Affiliation:
Naval Research Laboratory, Washington, DC 20375
E. Chang
Affiliation:
Naval Research Laboratory, Washington, DC 20375
K. Pilobello
Affiliation:
Nova Research, Alexandria, VA, E-mail: sulay@cbmse.nrl.navy.mil, foos@ccs.nrl.navy.mil
E. Goldman
Affiliation:
Naval Research Laboratory, Washington, DC 20375
D. Lowy
Affiliation:
Nova Research, Alexandria, VA, E-mail: sulay@cbmse.nrl.navy.mil, foos@ccs.nrl.navy.mil
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Abstract

Using gel electrophoresis we demonstrate the attachment of short ssDNAs to a new type of water-soluble gold nanocluster that is encapsulated with ethylene oxide ligands. Initial experiments indicate that these DNA/nanocluster conjugates can subsequently be hybridized to a longer DNA template suggesting a pathway for nanofabrication of multi-cluster assemblies.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 735: Symposium C – Bioinspired Nanoscale Hybrid Systems , 2002 , C11.41
Copyright
Copyright © Materials Research Society 2003

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References

REFERENCES

1. Much of industrial chemistry, materials science and metallurgy may be viewed as nanotechnology in that they exploit organization and/or activity at the nanoscale. They represent primitive nanotechnology in that they tend to be homogeneous, near-equilibrium and with minimal information content. More sophisticated is digital electronics technology that has sub-100nm nominal minimum feature sizes in production.Google Scholar
2. Alivisatos, A. P., Johnsson, K. P., Peng, X., Wilson, T. E., Loweth, C. J., Bruchez, M. P., and Schultz, P. G., Nature 382, 609 (1996);Google Scholar
Loweth, C.J., Caldwell, W.B., Peng, X., Alivisatos, A.P. and Schultz, P.G., Angew. Chem. Int. Ed. 38, 1808 (1999).Google Scholar
3. Mirkin, C. A., Letsinger, R. L., Mucic, R. C., and Storhoff, J. J., Nature 382, 607 (1996).Google Scholar
4. Zanchet, D., Micheel, C. M., Parak, W. J., Gerion, D., and Alivisatos, A. P., Nano Letters 1, 32 (2001).Google Scholar
5. Foos, E. E., Snow, A. W., Twigg, M. E., and Ancona, M. G., Chem. Mater. 14, 2401 (2002).Google Scholar
6. Armstrong, J. K., Leharne, S. A., Stuart, B. H., Snowden, M. J., and Chowdhry, B. Z., Langmuir 17, 4482 (2001).Google Scholar