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Dimac: A New Delivery System for Silver Sulfadiazine

Published online by Cambridge University Press:  26 February 2011

Linden M. Miller  and
John F. Hansbrough
Linden M. Miller
Affiliation:
Department of Surgery, University of California, San Diego Medical Center 225 Dickinson Street, San Diego, California 92103
John F. Hansbrough
Affiliation:
Department of Surgery, University of California, San Diego Medical Center 225 Dickinson Street, San Diego, California 92103
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Abstract

Wound care for burn victims is painful and tedious, but necessary to avoid the ever-present problem of infection. In an effort to circumvent daily dressing changes while ensuring optimal wound protection, DIMAC, a new drug delivery system for the commonly used topical antimicrobial silver sulfadlazine, has been developed. When incorporated into the delivery system, silver sulfadiazine is released in a sustained fashion. The results of an evaluation of the safety and efficacy of DIMAC in the treatment of full-and partial-thickness burn wounds are described here. DIMAC, left In place for up to 4 days, appears to be as effective as twice-daily cleansing and application of silver sulfadiazine cream.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 110: Symposium M – Biomedical Materials and Devices , 1987 , 425
Copyright
Copyright © Materials Research Society 1988

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References

1. Miller, L., Hansbrough, J.F.: “DIMAC, a new delivery system for silver sulfadiazine.” International Congress on Burns, Geneva, Switzerland, June 22–26, 1987.Google Scholar
2. Jordan, M., Oswald, A., Krob, M., and Lewis, M.: “IN-VIVO evaluation of efficacy of a sustained-release delivery system for silver sulfadiazine.” American Burn Association, Chicago, Illinois, April 9–12, 1986.Google Scholar