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Persistent Inhibition of Cell Growth on Silver Implanted Glassy Polymeric Carbon

Published online by Cambridge University Press:  01 February 2011

Robert L. Zimmerman ,
Ismet Gürhan ,
F. Ozdal-Kurt ,
B. H. Sen ,
Marcello Rodrigues  and
Daryush Ila
Robert L. Zimmerman
Affiliation:
rlzimm@cim.aamu.edu, Alabama A&M University, Radiation Center, 4900 Meridian Street, Normal, AL, 35762, United States, 256 372 5854, 256 372 5868
Ismet Gürhan
Affiliation:
ismetgurhan@yahoo.com, Ege University, Faculty of Engineering, Izmir, 87985, Turkey
F. Ozdal-Kurt
Affiliation:
fozdal@yahoo.com, CBU Faculty of Science, Manisa, 45673, Turkey
B. H. Sen
Affiliation:
bhsen@yahoo.com, EU Faculty of Dentistry, Izmir, 34679, Turkey
Marcello Rodrigues
Affiliation:
mrodrigues@dfm.ffclrp.usp.br, University of São Paulo, Ribeirão Preto, 49100, Brazil
Daryush Ila
Affiliation:
ila@cim.aamu.edu, Alabama A&M University, 4900 Meridian Street, Normal, AL, 35762, United States
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Abstract

We have shown that silver ion implantation or argon ion assisted surface deposition of silver inhibits cell growth on Glassy Polymeric Carbon (GPC), a desirable improvement of current cardiac implants. In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that near surface implantation of silver in GPC can completely inhibit cell attachment on implanted areas while leaving adjacent areas vulnerable to strong cell adhesion. After cleaning and sterilization and more than one year in physiologic solution, the silver implanted GPC persists in inhibiting cell attachment.

Keywords

Cbiomedicaladhesion
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 950: Symposium D – Biosurfaces and Biointerfaces , 2006 , 0950-D04-19
Copyright
Copyright © Materials Research Society 2007

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References

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