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Quartz tuning fork as a mass sensitive biosensor platform with a bi-layer film modification via plasma polymerization

Published online by Cambridge University Press:  03 May 2019

Hatice Ferda Özgüzar ,
Gizem Kaleli Can ,
Gözde Kabay  and
Mehmet Mutlu
Hatice Ferda Özgüzar
Affiliation:
Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Division, Graduate School of Science and Technology, TOBB University of Economics and Technology, Ankara 06560, Turkey
Gizem Kaleli Can
Affiliation:
Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Division, Graduate School of Science and Technology, TOBB University of Economics and Technology, Ankara 06560, Turkey Department of Biomedical Engineering, İzmir Democracy University, İzmir 35140, Turkey
Gözde Kabay
Affiliation:
Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Division, Graduate School of Science and Technology, TOBB University of Economics and Technology, Ankara 06560, Turkey
Mehmet Mutlu*
Affiliation:
Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Division, Graduate School of Science and Technology, TOBB University of Economics and Technology, Ankara 06560, Turkey Plasma Aided Biomedical Research Group (pabmed), Department of Biomedical Engineering, TOBB University of Economics and Technology, Ankara 06560, Turkey
*
Address all correspondence to Mehmet Mutlu at m.mutlu@etu.edu.tr
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Abstract

Due to the lack of the stability of amine films, a promising transducer, quartz-tuning fork (QTF) prongs were modified by a bi-layer film of plasma-polymerized n-heptane (hep) and then by ethylenediamine (EDA), respectively. For this purpose, the authors investigate the stability of amine-rich thin films both in air and aqueous medium. EDA films were deposited on QTF substrates by using an RF plasma system. The final amine-rich thin film was used to immobilize biologic recognition element. Model protein studies were showed that selected thin films could be adapted to QTF transducers to be used as a biosensor template.

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Type
Research Letters
Information
MRS Communications , Volume 9 , Issue 2 , June 2019 , pp. 710 - 718
Copyright
Copyright © Materials Research Society 2019 

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Footnotes

*

On leave.

References

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