Published online by Cambridge University Press: 18 January 2016
Understanding spatial and temporal neuronal activities is crucial for finding thecure for brain related ailments and advancement of our knowledge about the brainitself. This paper discusses our recent finding of the patternable roughtextured gold microwire for neurochemical sensing. We have successfullyfabricated the ∼5 µm wide and ∼ 60 nm thick goldmicrowires based electrochemical sensor. We produced these microwires along theedge of lithographically patterned nickel thin film. A nickel thin film edge wasshadowed by the photoresist overhang during electrochemical growth only to allowgold deposition along the edges. Our electrochemical growth conditions yieldedvery rough textured sensor. Rough textured biosensors are highly desirable forincreasing surface/volume ratio for efficient electrochemical sensing. Theserough-textured microwires were transformed into the functional neurochemicalsensor to detect dopamine. Our voltammetry and chronoamperometry studies onrough textured microwires based sensor confirmed the successful detection ofdopamine.