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3D conformal, IMRT and VMAT for the treatment of head and neck cancer: a brief literature review

Published online by Cambridge University Press:  09 December 2020

Kazi T. Afrin  and
Salahuddin Ahmad Open the ORCID record for Salahuddin Ahmad [Opens in a new window]
Kazi T. Afrin
Affiliation:
Department of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, P.O. Mirzanagar, Savar, Dhaka, 1344, Bangladesh
Salahuddin Ahmad*
Affiliation:
Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
*
Author for correspondence: Salahuddin Ahmad, Department of Radiation Oncology, University of Oklahoma Health Sciences Center, 800 NE 10th St, SCC L100, Oklahoma City, OK73104, USA. E-mail: Salahuddin-ahmad@ouhsc.edu
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Abstract

Aim:

The objective of this study has been to identify monitor unit (MU) and treatment time variations, volume coverage dissimilarity among 3D conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) treatment plans for head and neck cancer (HNC) based on literature review.

Methods:

A number of HNC cases were studied with the investigation of conformity and homogeneity index.

Results:

When high-dose modulation was required around small organs at risk (OARs), a clinically acceptable IMRT plan was achieved as VMAT usually required longer dose optimisation time. The greatest benefit of VMAT has been rapid treatment delivery allowing improved patient comfort, reduced intra-fraction motion and increased patient throughput. In some papers, 3D-CRT was shown not to meet well the requirements on parotid glands. One paper showed that cerebellum dose was lower for 3D-CRT than IMRT. However, it was found in other papers that OAR sparing with 3D-CRT was reasonable but in complex cases not enough.

Conclusions:

IMRT usually consists of several treatment fields with different directions, hundreds of beam lets with modulated intensity, an advantage over 3D-CRT, whereas VMAT has advantage over IMRT due to rotating beam utilisation. VMAT has lower total MU and treatment times than IMRT and 3D-CRT, while maintaining similar dosimetric endpoints.

Keywords

Dosimetric comparison3D-CRTIMRTVMATHead & Neck Cancer
Type
Literature Review
Information
Journal of Radiotherapy in Practice , Volume 21 , Issue 2 , June 2022 , pp. 259 - 262
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Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

Verbakel, W, Cuijpers, JP, Hoffmans, D, et al. Volumetric intensity modulated arc therapy vs. conventional IMRT in head-and-neck cancer: a comparative planning and dosimetric study. Int J Radiat Oncol Biol Phys 2009; 74 (1): 252–259.CrossRefGoogle ScholarPubMed
Puri, DR, Chou, W, Lee, N. Intensity-modulated radiation therapy in head and neck cancers: dosimetric advantages and update of clinical results. Am J Clin Oncol 2005; 28 (4): 415–423.CrossRefGoogle ScholarPubMed
Wang, X, Eisbruch, A. IMRT for head and neck cancer: reducing xerostomia and dysphagia. J Radiat Res 2016; 57 (S1): i69–i75.CrossRefGoogle ScholarPubMed
Elith, C, Dempsey, SE, Findlay, N et al. An Introduction to the Intensity-modulated radiation therapy (IMRT) techniques, Tomotherapy, and VMAT. J Med Imaging Radiat Sci 2011; 42 (1): 37–43.CrossRefGoogle Scholar
Byungchul, C. Intensity-modulated radiation therapy: a review with a physics perspective. Radiat Oncol J 2018; 36 (1): 1–10.Google Scholar
Mann, AK, Indira, AP, David, MP. Recent advances in radiotherapy for head and neck cancer: a comprehensive review. Int J Contemp Med Res 2017; 4 (4): 927–932.Google Scholar
Gomez, D, Cahlon, O, Mechalakos, J et al. An investigation of intensity-modulated radiation therapy versus conventional two-dimensional and 3D-conformal radiation therapy for early stage larynx cancer. Radiat Oncol 2010; 5: 74.CrossRefGoogle ScholarPubMed
Pfister, DG, Laurie, SA, Weinstein, GS et al. American society of clinical oncology clinical practice guideline for the use of larynx-preservation strategies in the treatment of laryngeal cancer. J Clin Oncol 2006; 24: 3693–3704.CrossRefGoogle Scholar
Teshima, T, Chatani, M, Inoue, T. Radiation therapy for early glottic cancer (T1N0M0): I. Results of conventional open field technique. Int J Radiat Oncol Biol Phys 1989; 17: 1199–1202.CrossRefGoogle ScholarPubMed
Chera, BS, Amdur, RJ, Morris, CG et al. Carotid-sparing intensity- modulated radiotherapy for early stage squamous cell carcinoma of the true vocal cord. Int J Radiat Oncol Biol Phys 2010; 77 (5): 1380–1385.CrossRefGoogle ScholarPubMed
Rosenthal, DI, Fuller, CD, Barker, JL et al. Simple carotid-sparing intensity-modulated radiotherapy technique and preliminary experience for T1–2 glottic cancer. Int J Radiat Oncol Biol Phys 2010; 77 (2): 455–461.CrossRefGoogle ScholarPubMed
Dobbler, B, Weidner, K, Koelbl, O. Application of volumetric modulated arc therapy (VMAT) in a dual vendor environment. Radiat Oncol 2010; 5: 95.CrossRefGoogle Scholar
Matthiesen, C, Herman, TDLF, Singh, H et al. Dosimetric and radiobiologic comparison of 3D conformal, IMRT, VMAT and proton therapy for the treatment of early-stage glottic cancer. J Med Imag Radiat Oncol 2015; 59: 221–228.CrossRefGoogle ScholarPubMed
Curran, B. Where goes the Peacock? Med Dosim 2001; 26 (1): 3–9.CrossRefGoogle Scholar
Hong, TS, Ritter, MA, Tomé, WA et al. Intensity-modulated radiation therapy: emerging cancer treatment technology. Br J Cancer 2005; 92 (10): 1819–1824.CrossRefGoogle ScholarPubMed
Studenski, MT, Bar-Ad, V, Siglin, J et al. Clinical experience transitioning from IMRT to VMAT for head and neck cancer. Med Dosim 2013; 38 (2): 171–175.CrossRefGoogle ScholarPubMed
Teoh, M, Clark, CH, Wood, K et al. Volumetric modulated arc therapy: a review of current literature and clinical use in practice. Br J Radiol 2011; 84: 967–996.CrossRefGoogle ScholarPubMed
Holt, A, Gestel, DV, Arends, MP et al. Multi-institutional comparison of volumetric modulated arc therapy vs. intensity-modulated radiation therapy for head-and-neck cancer: a planning study. Radiat Oncol 2013; 8: 26.CrossRefGoogle ScholarPubMed
Peszynska-Piorun, M, Malicki, J, Golusinski, W. Doses in organs at risk during head and neck radiotherapy using IMRT and 3D-CRT. Radiol Oncol 2012; 46 (4): 328–336.CrossRefGoogle ScholarPubMed
Portakal, ZG, Tunali, C. A comparative treatment planning study of intensity modulated radiotherapy and 3-D conformal radiotherapy for head and neck cancer. In: Conference: RAD 2014. doi: 10.13140/RG.2.1.2215.2168.CrossRefGoogle Scholar
Sankaralingam, M, Glegg, M, Smith, S et al. Quantitative comparison of volumetric modulated arc therapy and intensity modulated radiotherapy plan quality in sino-nasal cancer. J Med Phys 2012; 37 (1): 8–13.CrossRefGoogle ScholarPubMed
Johnston, M, Clifford, S, Bromley, R et al. Volumetric-modulated arc therapy in head and neck radiotherapy: a planning comparison using simultaneous integrated boost for nasopharynx and oropharynx carcinoma. Clin Oncol 2011; 23 (8): 503–511.CrossRefGoogle ScholarPubMed
Ferreira, BC, Lopes, MC, Mateus, J et al. Radiobiological evaluation of forward and inverse IMRT using different fractionations for head and neck tumours. Radiat Oncol 2010; 5: 57.CrossRefGoogle ScholarPubMed
Nithya, L, Raj, NA, Kumar, A et al. Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer. J Med Phys 2014; 39 (2): 121–126.CrossRefGoogle ScholarPubMed
Singh, R, Rawat, S, Bhushan, M. RapidArc vs IMRT: our experience in head and neck cancers-a dosimetric study. J Radiol Radiat Ther 2017; 5 (1): 1067.Google Scholar