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Myanesin in Psychiatry

Published online by Cambridge University Press:  08 February 2018

A. B. Monro  and
H. H. Steadman
A. B. Monro
Affiliation:
Long Grove Hospital, Epsom
H. H. Steadman
Affiliation:
Long Grove Hospital, Epsom
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Extract

In the course of a systematic investigation of the pharmacological properties of a-substituted glycerol ethers it was found that some of these compounds produced muscular relaxation and paralysis. In small doses, administered sub-cutaneously, muscular relaxation and a sleep-like condition were produced in laboratory animals—in larger doses there was ataxia followed by paralysis. Of the various compounds studied, mephenesin was found to be the most potent and to possess the greatest margin of safety, and it is this product which is used, for oral administration, in Myanesin Elixir.

Information

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 99 , Issue 415 , April 1953 , pp. 285 - 287
Copyright
Copyright © Royal College of Psychiatrists, 1953 

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References

Freudenberg, R., “Observations of the Effect of Myanesin on Epileptic Thresholds and some Psychiatric Conditions,” J. Ment. Sci., 1950, 96, 751.Google Scholar
Paster, S., and Holzman, S. C., “A Study of 1,000 Psychotic Veterans treated with Insulin and Electric Shock,” Am. J. Psychiat., 1949, 105, 811.Google Scholar
Schlan, and Unna, , “Some Effects of Myanesin in Psychiatric Patients,” J. Amer. Med. Ass., 1949, 140, 672.Google Scholar
Ström-Olsen, R., “Pharmacotherapy in Psychiatry,” Practitioner, 1951, 167, 140.Google Scholar
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