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A Controlled Trial of Imipramine (“Tofranil”) in the Treatment of Severe Depressive States

Published online by Cambridge University Press:  08 February 2018

Linford Rees ,
A. C. Brown  and
S. Benaim
Linford Rees
Affiliation:
Department of Psychological Medicine, St. Bartholomew's Hospital Consultant Physician Bethlem Royal and the Maudsley Hospital, London
A. C. Brown
Affiliation:
Bethlem Royal and the Maudsley Hospital
S. Benaim
Affiliation:
Halliwick Hospital
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Extract

The discovery by Kuhn (1957) that an iminodibenzyl derivative (imipramine) was therapeutically successful in depressive illnesses aroused great interest and stimulated clinical trials with the drug in many parts of the world. The results of some of the published reports are given in summarized form in Table I.

Information

Type
Original Articles
Information
Journal of Mental Science , Volume 107 , Issue 448 , May 1961 , pp. 552 - 559
Copyright
Copyright © Royal College of Psychiatrists, 1961 

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