Though many writers have advocated the use of digitalis in various forms of insanity—such as acute, paralytic, or epileptic mania—yet there appears to be great diversity of opinion as to its efficacy, great variety in the methods of administering it, and a wide range in the quantities prescribed. While one has been content to order five to ten minims of the tincture three or four times a day, another has given, in similar cases, single doses of half-an-ounce of the same preparation.