Hostname: page-component-5447f9dfdb-6cxwp Total loading time: 0 Render date: 2025-07-28T16:20:20.886Z Has data issue: false hasContentIssue false
  • English
  • Français

Role of KTP-532 laser in management of oral submucous fibrosis

Published online by Cambridge University Press:  10 October 2008

D R Nayak ,
S G Mahesh ,
D Aggarwal ,
P Pavithran ,
K Pujary  and
S Pillai
D R Nayak
Affiliation:
Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal, India
S G Mahesh
Affiliation:
Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal, India
D Aggarwal
Affiliation:
Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal, India
P Pavithran
Affiliation:
Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal, India
K Pujary*
Affiliation:
Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal, India
S Pillai
Affiliation:
Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal, India
*
Address for correspondence: Dr Kailesh Pujary, Associate Professor, Department of ENT – Head and Neck Surgery, Kasturba Medical College and Hospital, Manipal 576104, Karnataka, India. Fax: 0091 820 2570061 E-mail: pujarykp@rediffmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Introduction:

Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. Various treatment modalities are available for its management, but these have largely been ineffective.

Materials and methods:

Nine cases of oral submucous fibrosis underwent a release procedure using a KTP-532 laser, from March 2005 to January 2006, within the ENT – head and neck surgery department of a tertiary centre.

Results:

Pre- and post-operative mouth-opening was compared using the Wilcoxon signed rank test, and a significant difference observed (Z = −2.690, p = 0.007). Follow up over an average period of 12 months showed encouraging results.

Conclusion:

This preliminary study indicated that adequate release of oral submucous fibrosis can be achieved by using a KTP-532 laser release procedure, with minimal morbidity and satisfactory results. These promising results should encourage more widespread use of this technique in the management of this condition.

Keywords

Oral CavityFibrosisLaser Surgery

Information

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 4 , April 2009 , pp. 418 - 421
Copyright
Copyright © JLO (1984) Limited 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

1 Schwartz, J. Atrophia idiopathica mucosa oris. Presented at the 11th International Dental Congress, London; 1952Google Scholar
2 Pindborg, JJ. Oral precancerous conditions in south East Asia. Int Dent J 1965;15:190–8Google ScholarPubMed
3 Khanna, JN, Andrade, NN. Oral submucous fibrosis: a new concept in surgical management. Report of 100 cases. Int J Oral Maxillofac Surg 1995;24:433–9CrossRefGoogle ScholarPubMed
4 Wei, FC, Chang, YM, Kildal, M, Tsang, WS, Chen, HC. Bilateral small radial forearm flaps for reconstruction of buccal mucosa after surgical release of submucosal fibrosis: a new reliable approach. Plast Reconstr Surg 2001;107:1679–82CrossRefGoogle ScholarPubMed
5 Haque, MF, Meghji, S, Nazir, R, Harris, M. Interferon gamma (INF-gamma) may reverse oral submucous fibrosis. J Oral Pathol Med 2001;30:12–21CrossRefGoogle Scholar
6 Yeh, CY. Application of the buccal fat pad to the surgical treatment of oral submucous fibrosis. Int J Oral Maxillofac Surg 1996;25:130–3CrossRefGoogle Scholar
7 Celik, Naci, Wei, FC, Chang, YM. Squamous cell carcinoma of the oral mucosa after release of submucous fibrosis and bilateral radial forearm flap reconstruction. Plast Reconstr Surg 2002;110:34–8CrossRefGoogle ScholarPubMed
8 Zain, RB, Ikeda, N, Gupta, PC, Warnakulasuriya, S, Van Wyk, CW, Shrestha, P et al. Oral mucosal lesions associated with betel quid, areca nut and tobacco chewing habits. J Oral Pathol Med 1999;28:1–4CrossRefGoogle ScholarPubMed
9 Tilakaratne, WM, Klinikowski, MF, Saku, T, Peters, TJ, Warnakulasuriya, S. Oral submucous fibrosis: review on aetiology and pathogenesis. Oral Oncol 2006;42:561–8CrossRefGoogle ScholarPubMed
10 Harvey, W, Scutt, A, Meghji, S, Canniff, JP. Stimulation of human buccal mucosa fibroblasts in vitro by betel nut alkaloids. Arch Oral Bio 1986;31:45–9CrossRefGoogle ScholarPubMed
11 Canniff, JP, Harris, M. Oral submucous fibrosis: its pathogenesis and management. Br Dent J 1986;160:429–34CrossRefGoogle Scholar
12 Sumeth Perera, MW, Gunasinghe, D, Perera, PA, Ranasinghe, A, Amaratunga, P, Warnakulasuriya, S et al. Development of an in vivo mouse model to study oral submucous fibrosis. J Oral Pathol Med 2007;36:273–80CrossRefGoogle Scholar
13 Kakar, PK. Oral submucous fibrosis; treatment with hyalase. J Laryngol Otol 1985;99:57–62CrossRefGoogle ScholarPubMed
14 Gupta, DS, Gupta, MK, Golhar, BL. Oral submucous fibrosis; clinical study and management by physiofibrolysis. J Indian Dent Assoc 1980;52:375–8Google Scholar
15 Bergler, W. Laser use in the oral cavity and oropharynx. In: Huettenbrink, K-B, ed. Current Topics in Otolaryngology – Head and Neck Surgery. Lasers in Otorhinolaryngology. Stuttgart, New York: Thieme, 2005;78–80Google Scholar