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Silent middle ear dysfunction due to underlying laryngopharyngeal reflux disease: can it be reversed with anti-reflux therapy?

Published online by Cambridge University Press:  02 May 2025

Probal Chatterji
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, UP, India
Yashodeep Mukherjee*
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, UP, India
Suvam Pati
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, UP, India
*
Corresponding author: Yashodeep Mukherjee; Email: ymukherjee2014@gmail.com

Abstract

Objectives

Laryngopharyngeal reflux disease can affect functioning of Eustachian tube which is responsible for maintenance of normal middle ear physiology. Our study aims to assess the effect of laryngopharyngeal reflux disease on middle ear physiology and whether any functional derangement can be reversed by anti-reflux therapy.

Methods

Patients with both laryngopharyngeal reflux disease and asymptomatic middle ear dysfunction (n = 50) were prescribed anti-reflux therapy and followed up for eight weeks. Audiometric evaluations were done routinely to assess changes.

Results

Post-intervention, 72 per cent of affected ears had improved thresholds with reduction in mean and median over each serial evaluation (p = 0.003). Tympanograms showed reversal to normal in 38 per cent of cases with increasing compliance over each successive visit (p < 0.001).

Conclusion

Laryngopharyngeal reflux disease can result in middle ear dysfunction. Early detection and treatment is crucial for restoration of normalcy and prevention of progression to other complications.

Information

Type
Main Article
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

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Footnotes

Yashodeep Mukherjee takes responsibility for the integrity of the content of the paper

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