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Analysis of anteroposterior-to-transverse ratio in predicting thyroid malignancy on ultrasonography

Published online by Cambridge University Press:  14 February 2022

Q Guo Open the ORCID record for Q Guo [Opens in a new window] ,
J Li ,
J Xin  and
X Chen Open the ORCID record for X Chen [Opens in a new window]
Q Guo
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China Department of Otorhinolaryngology Head and Neck Surgery, Hebei Yanda Hospital, Langfang, China
J Li
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China Department of Otorhinolaryngology Head and Neck Surgery, Shanxi Provincial People's Hospital, Taiyuan, China
J Xin
Affiliation:
Department of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, China-Japan Union Hospital of Jilin University, Changchun, China
X Chen*
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China
*
Author for correspondence: Prof Xiaohong Chen, Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China E-mail: trchxh@163.com Fax: +86 010 5826 9258
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Abstract

Objective

To explore the diagnostic value of anteroposterior-to-transverse ratio for predicting thyroid cancer.

Methods

A total of 2306 nodules were divided into 5 groups according to their size. The ability of the anteroposterior-to-transverse ratio to predict thyroid cancer was analysed in each group on the basis of the sensitivity, specificity, accuracy and Youden index.

Results

The median anteroposterior-to-transverse ratio was 0.83, with an interquartile range of 0.28. The area under the receiver operating characteristic curve was 0.709 (p < 0.001). When the diameter of a thyroid nodule was less than 1.5 cm, an anteroposterior-to-transverse ratio of more than 0.9 was associated with higher sensitivity, accuracy and Youden index, compared with an anteroposterior-to-transverse ratio of greater than 1.0, but the specificity was lower. When the diameter of a thyroid nodule was 1.5 cm or more, an anteroposterior-to-transverse ratio of greater than 0.9 was associated with higher sensitivity and Youden index, compared with an anteroposterior-to-transverse ratio of greater than 1.0, but specificity and accuracy were lower.

Conclusion

The anteroposterior-to-transverse ratio was a meaningful indicator of thyroid cancer, and its predictive effectiveness could be influenced by nodule size.

Keywords

UltrasonographyThyroid NoduleThyroid Neoplasms
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 137 , Issue 5 , May 2023 , pp. 546 - 550
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Prof X Chen takes responsibility for the integrity of the content of the paper

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