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A kinetic model for Ascaridia galli populations in chickens treated with mixed salts of copper and zinc

Published online by Cambridge University Press:  11 April 2024

M. Gabrashanska ,
S. Teodorova ,
M. Galvez-Morros  and
O. Garcia Martinez
M. Gabrashanska
Affiliation:
Institute of Experimental Pathology and Parasitology, Bulgarian Academy of Sciences, Acad. G. Bonchev str., bl 25, 1113 Sofia, Bulgaria
S. Teodorova*
Affiliation:
Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, 72 Tzarigradsko shaussee, 1784 Sofia, Bulgaria
M. Galvez-Morros
Affiliation:
Departamento de Patologia, Facultad de Veterinaria, Universidad Complutense, Carreterade Puerto de Hierro s/n, 28040 Madrid, Spain
O. Garcia Martinez
Affiliation:
Instituto de Ciencia de Materiales, Serrano, 113 CSIC, 28006 Madrid, Spain
*
*Author for correspondence. Fax: +359 2 975 3619.
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Abstract

The action of mixed salts of copper and zinc (basic and neutral) on Hisex chickens experimentally infected with Ascaridia galli has been studied. The data show that the lowest host mortality and decrease in body weight gain and the highest reduction in nematode loading occurs in infected chickens treated with basic salts (in comparison with infected chickens, untreated or treated with neutral salts). A mathematical model has been proposed to provide a quantitative interpretation of the observed results. The model solutions of the kinetics of parasite numbers and of the gain in body weight are in a good agreement with the experimental data. One of the kinetic parameters in the model is defined as a phenomenological constant of the host immune response. Its value is determined in the case of infected and untreated chickens.

Type
Research Article
Information
Journal of Helminthology , Volume 73 , Issue 1 , January 1999 , pp. 45 - 50
Copyright
Copyright © Cambridge University Press 1999

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