Professional networking involves building intentional relationships to advance career development [Reference Dunn1,Reference Selvarajah, Zadeh, Kobti, Palanichamy and Kargar2]. Networks facilitate resource exchange, collaboration, skill development, and career progression [Reference Gibson, Hardy JH and Buckley3–Reference Fischer5]. Networks transfer tacit knowledge, spur innovation, and promote collaboration, mentorship, and resource access [Reference Heffernan6,Reference Ansmann, Flickinger and Barello7]. They also amplify social capital [Reference Burt8,Reference Mehra, Dixon, Brass and Robertson9], visibility, and leadership opportunities [Reference Cola and Wang10–Reference Rubio, Primack, Switzer, Bryce, Seltzer and Kapoor13]. While extremely valuable, networks can be challenging for an individual to establish or join if they are already in existence [Reference Porter, Woo, Alonso and Snyder4,Reference Goolsby and Knestrick14]. Thus, infrastructural support for professional networks beyond formal training programs could be advantageous. Therefore, we propose the need for infrastructural support for sustained and effective networking communities for multistage faculty at institutions, as well as models and guidelines of how to build them so they can be successful in enhancing career resilience and long-term success.
Past studies have underscored networks’ role in academic achievement. For example, Robinson et al. (2016) found that early-career awardees (NIH KL2/K12; N = 40) credited institutional, national, and international networks as key to their success [Reference Robinson, Schwartz, DiMeglio, Ahluwalia and Gabrilove15]. Viglianti et al. 2022, present a peer mentorship network of early career clinician-scientists in academic medicine (Multidisciplinary Intensive Care Research Workgroup-MICReW) [Reference Viglianti, Admon and Carlton16]. The program fostered accountability, exchange of opinions and feedback, and encouraged comradery and teamwork. Over the course of seven years, the peer network supported members to progress in academic positions and receive career development awards [Reference Viglianti, Admon and Carlton16].
Studies highlight the lack of structured professional networks to support scholars facing early and mid-career challenges [Reference Llewellyn, Adachi, Nehl and Heilman17,Reference Clegg, Josserand, Mehra and Pitsis18]. Llewellyn et al., 2021 present interview and focus group findings from alumni in a structured training seminar for pursuing NIH K awards (K-Club) [Reference Llewellyn, Adachi, Nehl and Heilman17]. Participants expressed the need for additional programs with a more flexible training format and opportunities for small-group interactions that can support professional networks [Reference Llewellyn, Adachi, Nehl and Heilman17]. Professional networking cannot be left to the spontaneous interactions and intuitive social skills of individual scholars. Instead, it is best fostered through infrastructures conducive to this process and is a need that trainees have identified. Martin, et al. 2023, present the notion and need for distributed mentoring in the context of networks formed by scholars from various experience levels. These networks can facilitate interactions and provide feedback, advice, and informal instruction [Reference Martin, Mori and Froehlich19]. Despite the need and benefits of structured professional networks, effective models and practices have received minimal scholarly attention [Reference Clegg, Josserand, Mehra and Pitsis18,Reference Bian, Xie, Topaloglu, Hudson, Eswaran and Hogan20].
Program Genesis
Columbia University Irving Medical Center’s (CUIMC), Clinical and Translational Science Award (CTSA) program includes TRANSFORM (TRaining And Nurturing Scholars FOr Research that is Multidisciplinary), which is the education core that supports research skill development, pilot funding, and career resources. The KL2 program as well as the TL1 are housed within TRANSFORM. The KL2 provided academic and funding support, essential to early successes as clinician-scientists. The conclusion of the program posed the risk of losing the collaborative environment that had nurtured KL2 scholars’ growth transitioning in 2017. To address this, we designed a program, EVOLUTION (Empowering Voices Of Leaders Using Training, Integration, and Ongoing Networks) that would extend support by building a professional network of alumni. EVOLUTION was designed to support career transitions from K to R/Center-level funding through intentional networking.
TRANSFORM EVOLUTION was born from scholars’ desire to create a structured community. By 2020, its mission expanded to build a sustainable, inclusive network fostering professional collaboration and social connection across career stages. The name “EVOLUTION” reflects its vision: an adaptive community responding to scholars’ evolving needs, emphasizing how professional networks enhance development. In translational science’s demanding landscape, we believe such peer networks will shape the field’s future and empower new generations of researchers.
Structure and Innovation
TRANSFORM EVOLUTION provides a structure for developing successful intentional professional networks (Table 1). EVOLUTION has been strengthened by the infrastructure provided through the Columbia University Irving Medical Center’s CTSA. The program operates with dedicated financial resources including a small budget for events per year. The support also included 2–4 hours per month of administrative support for coordinating logistics, managing communication, and sustaining engagement across the network. This integrative support structure enhances the program’s capacity for resource sharing, and long-term sustainability. CTSAs are uniquely positioned to offer this type of backbone infrastructure, spanning programmatic coordination, administrative continuity, and cross-campus integration that is critical for building and maintaining successful professional networks.
Table 1. TRANSFORM EVOLUTION framework

Abbreviations: CTSA = Clinical and Translational Science Award; CUIMC = Columbia University Irving Medical Center; Mentored Research Career Development Program Award, KL2; Ruth L. Kirschstein National Research Service Award (NRSA) Research Training Grant, TL1; Investigator-initiated Research Project (R01).
TRANSFORM EVOLUTION represents a novel approach to professional networking by creating an enduring, cross-career community for program alumni. Distinct from traditional hierarchical models that separate senior and junior scholars or peer networks limited to similar career stages, EVOLUTION intentionally integrates researchers across all academic ranks into a flexible, needs-responsive ecosystem. This innovative structure fosters horizontal collaboration where participants collectively problem-solve, generate ideas, develop new methodologies, and exchange insights regardless of career stage. By transcending conventional mentorship paradigms, the program addresses a critical gap in the literature while creating dynamic synergies that benefit early-career trainees and established faculty alike through participation and mutual support.
Impact and Continuity
The TRANSFORM EVOLUTION network fosters a sense of personal connection and belonging, giving members access to peer scholars and opportunities for collaboration and mentorship. It has positively impacted careers of many researchers (Figure 1).

Figure 1. Testimonials from TRANSFORM EVOLUTION network members about their experiences with the programming. Abbreviations: TRANSFORM = TRaining and nurturing scholars FOr research that is multidisciplinary; EVOLUTION = empowering voices of leaders using training, integration, and ongoing networks; mentored research career development program award KL2, internal K; POR = patient-oriented research colloquium.
At the core of TRANSFORM EVOLUTION is a deep commitment to the principles of mentorship and the importance of professional social networks. The program’s founders believed that an effective community would need to include multistage faculty to ensure peer and near peer support. Networking events are well-attended by faculty at every career stage. For example, events occurring between April 2022 and December 2024 had 42 unique attendees from every career stage, with some attendees having had no NIH grants and others having had 14 NIH grants in their academic lifetime. While senior faculty provide invaluable guidance based on their extensive experience, junior faculty contribute fresh perspectives and innovative approaches having recently navigated some of the benchmarks, applications, and promotion processes enriching the development of a support network. Exposure to structured leadership training and real-world mentorship experiences has equipped early career scholars with the skills needed to transition into independent investigator roles. The program’s robust KL2 alumni network plays a critical role in maintaining this culture. Alumni, many of whom are now leaders in their respective fields, remain actively engaged in the program and attend the networking events. This engagement not only provides current participants with access to seasoned colleagues but also allows alumni to contribute to the ongoing development of the next generation of clinician-scientists.
Sustainability and Future Directions
From its inception, TRANSFORM EVOLUTION was designed with sustainability in mind. A governance committee composed of scholars at different stages provides leadership, ensuring that programming remains responsive and relevant. We are planning to further define effective practices and structures of the program and establish program outcomes to monitor its success. Looking ahead, the program aims to expand cross-institutional collaborations with other CTSA sites and translational research networks while also developing robust evaluation frameworks to track participants’ progress and refine offerings. In the long term, we aim to disseminate our program regionally and nationally, integrating it into the broader academic and professional development infrastructure, through our career development sessions that could include smaller group break outs. In translational science’s demanding landscape, we believe such peer networks will shape the field’s future and empower new generations of researchers.
Acknowledgments
Irving Institute for Clinical and Translational Research, Authors (in Alphabetical Order). Crystal Denizé, BS, TRANSFORM, Senior Program Coordinator. Sandra Soo-Jin Lee, PhD, Director; Associate Director, Regulatory Knowledge and Ethics Resource. Harley Lynch, MS, TRANSFORM, Assistant Director. Harold Pincus, MD, Co-Director; Director, Evaluation and Continuous Improvement. Muredach P. Reilly, MBBCh, MSCE, Director. Helena Rincón, MA, Associate Director, Finance and Administration.
Author contributions
Marisa Spann: Conceptualization, data curation, formal analysis, funding acquisition, investigation, methodology, project administration, supervision, visualization, writing – original draft, writing – review & editing; May Hua: visualization, writing – original draft, writing – review & editing; Daichi Shimbo: conceptualization, funding acquisition, resources, writing – original draft, writing – review & editing; Melissa Begg: conceptualization, funding acquisition, resources, supervision, writing – original draft, writing – review & editing; Robyn Gartrell: writing – original draft, writing – review & editing; Fatemeh Momen-Heravi: writing – original draft, writing – review & editing; Melissa Accordino: writing – original draft, writing – review & editing; Eileen Connolly: writing – original draft, writing – review & editing; Andrew Einstein: writing – original draft, writing – review & editing; Katherine Dimitropoulou: conceptualization, data curation, visualization, writing – original draft, writing – review & editing; Bernard Chang: conceptualization, data curation, supervision, writing – original draft, writing – review & editing; Badri Vardarajan: conceptualization, data curation, funding acquisition, resources, writing – original draft, writing – review & editing.
Funding statement
We would like to thank our funders from NCATS grants: CTSA current UL1TR001873 and former UL1TR000040; and KL2 Mentoring Career Development Award, current KL2TR001874 and former KL2TR000081; and TL1 Training Program, current TL1TR001875 and former TL1TR000082; and National Institute of Mental Health (NIMH) K24MH127381.
Competing interests
The authors have no biomedical financial interest or potential conflicts of interest.