Hostname: page-component-857557d7f7-d5hhr Total loading time: 0 Render date: 2025-12-10T04:30:26.344Z Has data issue: false hasContentIssue false

Integrating gaming disorder into early intervention in first-episode psychosis – current knowledge and future directions

Published online by Cambridge University Press:  09 December 2025

Maxime Huot-Lavoie*
Affiliation:
Faculty of Medicine, Université Laval, Quebec city, QC, Canada CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada
Olivier Cobeil
Affiliation:
CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada Faculty of Pharmacy, Université Laval, Québec city, QC, Canada
Olivier Roy
Affiliation:
Faculty of Medicine, Université Laval, Quebec city, QC, Canada CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada
Sophie L’Heureux
Affiliation:
Faculty of Medicine, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada
Magali Dufour
Affiliation:
Department of psychologie, Université du Québec à Montréal, Montreal, QC, Canada
Josiane Lavallée
Affiliation:
Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada
Laurent Béchard
Affiliation:
CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada Faculty of Pharmacy, Université Laval, Québec city, QC, Canada Faculty of Nursing, Université Laval, Québec city, QC, Canada
Sébastien Brodeur
Affiliation:
Faculty of Medicine, Université Laval, Quebec city, QC, Canada CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada
Marie-France Demers
Affiliation:
CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada Faculty of Pharmacy, Université Laval, Québec city, QC, Canada
Marc-André Roy
Affiliation:
Faculty of Medicine, Université Laval, Quebec city, QC, Canada CERVO Brain Research Centre, Université Laval, Quebec city, QC, Canada Clinique Notre-Dame des Victoires, Centre intégré universitaire en santé et services sociaux de la Capitale Nationale, Québec city, QC, Canada
Yasser Khazaal
Affiliation:
Department of Psychiatry, Lausanne University, Lausanne, Switzerland Lausanne University Hospital Research Center, Lausanne, Switzerland
*
Corresponding author: Maxime Huot-Lavoie; Email: maxime.huot-lavoie.1@ulaval.ca
Rights & Permissions [Opens in a new window]

Abstract

Gaming disorder (GD) is increasingly recognized as a clinically significant condition, yet its implications in first-episode psychosis (FEP) remain largely unexplored. This perspective article focuses on the intersection of GD and FEP, highlighting key diagnostic and treatment challenges, including symptom overlap that complicates differential diagnosis, the absence of validated screening tools, and difficulties in sustained patient engagement. Drawing insights from substance use disorder management in FEP, we propose a preliminary clinical framework for integrating GD assessment and intervention into early intervention in psychosis programs. This approach prioritizes comprehensive evaluation, patient-centered care, and a harm-reduction model that supports digital well-being. Addressing GD inFEP populations is crucial for optimizing functional recovery and promoting a holistic, recovery-oriented approach to psychiatric care. Further research is needed to refine screening tools and validate tailored interventions in this population.

Information

Type
Review Article
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use and/or adaptation of the article.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of College of Psychiatrists of Ireland

Introduction

Gaming disorder (GD) was recognized by the World Health Organization in the ICD-11 as a behavioral addiction, characterized by impaired control over gaming, prioritization of gaming over other activities, and continued gaming despite negative consequences (WHO, 2019). A meta-analysis estimates its prevalence at 3.3% in the general population (Kim et al. Reference Kim, Son, Roh, Ahn, Kim, Shin, Chey and Choi2022). While gaming can enhance cognitive functions and foster social connections (Granic et al. Reference Granic, Lobel and Engels2014, Quiles & Verdoux, Reference Quiles and Verdoux2023), GD is associated with anxiety, depression, functional impairments, interpersonal conflict, social withdrawal, and academic or occupational difficulties (Ji et al. Reference Ji, Yin, Zhang and Wong2022, Richard et al. Reference Richard, Temcheff and Derevensky2020).

GD frequently co-occurs with psychiatric conditions, including attention-deficit/hyperactivity disorder, mood disorders, and anxiety disorders, though causal relationships remain unclear (Ahmed et al. Reference Ahmed, Abdalla, Mohamed, Mohamed and Shamaa2022, VAN et al. Reference van Rooij, Kuss, Griffiths, Shorter, Schoenmakers and van de Mheen2014, Hygen et al. Reference Hygen, Skalicka, Stenseng, Belsky, Steinsbekk and Wichstrom2020, Lee et al. Reference Lee, Bae, Kim and Han2021, Gonzalez-Bueso et al. Reference González-Bueso, Santamaría, Fernández, Merino, Montero and Ribas2018, Huot-Lavoie et al. Reference Huot-Lavoie, Gabriel-Courval, Béchard, Corbeil, Brodeur and Massé2023) However, its prevalence, clinical impact, and mechanisms of co-occurrence with more severe psychiatric conditions, particularly psychotic disorders, remain poorly understood (Huot-Lavoie et al. 2022, González-Bueso et al. Reference González-Bueso, Santamaría, Fernández, Merino, Montero and Ribas2018).

Psychotic disorders and the importance of early intervention

Psychotic disorders encompass multiple symptom domains, including positive symptoms (delusions, hallucinations), cognitive and disorganized symptoms, mood-related symptoms (anxiety, depression), agitation and hostility, negative symptoms (diminished affect and reduced motivation), and manic symptoms, which are more common in bipolar spectrum or schizoaffective disorders (Lehoux et al. Reference Lehoux, Lefebvre, Maziade, Roy and Gobeil2009, American Psychiatric Association, 2013).

Reducing the duration of untreated psychosis is critical for improving long-term clinical outcomes (Marshall et al. Reference Marshall, Lewis, Lockwood, Drake, Jones and Croudace2005, Perkins et al. Reference Perkins, Gu, Boteva and Lieberman2005, Correll et al. Reference Correll, Galling, Pawar, Krivko, Bonetto, Ruggeri, Craig, Nordentoft, Srihari, Guloksuz, Hui, Chen, Valencia, Juarez, Robinson, Schooler, Brunette, Mueser, Rosenheck, Marcy, Addington, Estroff, Robinson, Penn, Severe and Kane2018). Early intensive, age-appropriate intervention programs have demonstrated superior outcomes compared to standard treatment, particularly for first-episode psychosis (FEP) (Correll et al. Reference Correll, Galling, Pawar, Krivko, Bonetto, Ruggeri, Craig, Nordentoft, Srihari, Guloksuz, Hui, Chen, Valencia, Juarez, Robinson, Schooler, Brunette, Mueser, Rosenheck, Marcy, Addington, Estroff, Robinson, Penn, Severe and Kane2018).

The need for a comprehensive approach to recovery

Pharmacological treatments play a critical role in FEP management, achieving remission of positive symptoms in approximately 80% of patients within the first year (Robinson et al. Reference Robinson, Woerner, McMeniman, Mendelowitz and Bilder2004, Malhi et al. Reference Malhi, Adams, Moss and Walter2010). However, symptom remission does not equate to full recovery, as many individuals experience persistent functional impairments, social withdrawal, and difficulties in personal and occupational domains. When broader recovery measures – such as social reintegration, autonomy, and life satisfaction – are considered, only 21% with FEP achieve full recovery (Hansen et al. Reference Hansen, Speyer, Starzer, Albert, Hjorthøj, Eplov and Nordentoft2023). This underscore the need for holistic approaches that extend beyond symptom management to encompass functional, social, psychological, and personal health dimension (Roy MA et al. Reference Roy, Cellard, Côté, Demers, Lehoux, Menear, Morin, Péloquin and Vigneault2024).

In addition to many issues associated with psychotic disorders, comorbidities significantly influence recovery engagement and outcomes (Wade et al. Reference Wade, Harrigan, McGorry, Burgess and Whelan2007, Wisdom et al. Reference Wisdom, Manuel and Drake2011, Blanchard et al. Reference Blanchard, Brown, Horan and Sherwood2000, Volkow, Reference Volkow2009, Thoma & Daum, Reference Thoma and Daum2013). Substance use disorders (SUD), which are highly prevalent in psychotic disorders (Baker et al. Reference Baker, Hiles, Thornton, Hides and Lubman2012, Hunt et al. Reference Hunt, Siegfried, Morley, Brooke-Sumner and Cleary2019, Rygaard Hjorthoj et al. Reference Rygaard Hjorthoj, Baker, Fohlmann and Nordentoft2014, Sara et al. Sara et al. Reference Sara, Burgess, Malhi, Whiteford and Hall2014), are associated with earlier psychosis onset (Donoghue et al. Reference Donoghue, Doody, Murray, Jones, Morgan, Dazzan, Hart, Mazzoncini and MacCabe2014, Di Forti et al. Reference Di Forti, Sallis, Allegri, Trotta, Ferraro, Stilo, Marconi, La Cascia, Reis Marques, Pariante, Dazzan, Mondelli, Paparelli, Kolliakou, Prata, Gaughran, David, Morgan, Stahl, Khondoker, MacCabe and Murray2014, Addington & Addington, Reference Addington and Addington2007), greater symptoms severity (Wade et al. Reference Wade, Harrigan, Edwards, Burgess, Whelan and McGorry2006, Sorbara et al. Reference Sorbara, Liraud, Assens, Abalan and Verdoux2003, Abdel-Baki et al. Reference Abdel-Baki, Ouellet-Plamondon, Salvat, Grar and Potvin2017, Addington & Addington, Reference Addington and Addington2007, Harrison et al. Reference Harrison, Joyce, Mutsatsa, Hutton, Huddy, Kapasi and Barnes2008, Wade et al. Reference Wade, Harrigan, McGorry, Burgess and Whelan2007, Linszen & van Amelsvoort, Reference Linszen and van Amelsvoort2007), higher relapse rates (Malla et al. Reference Malla, Norman, Bechard-Evans, Schmitz, Manchanda and Cassidy2008, Alvarez-Jimenez et al. Reference Alvarez-Jimenez, Priede, Hetrick, Bendall, Killackey, Parker, McGorry and Gleeson2012, Foti et al. Reference Foti, Kotov, Guey and Bromet2010, González-Pinto et al. Reference Gonzalez-Pinto, Alberich, Barbeito, Gutierrez, Vega, Ibanez, Haidar, Vieta and Arango2011, Lambert et al. Reference Lambert, Conus, Lubman, Wade, Yuen, Moritz, Naber, McGorry and Schimmelmann2005), poorer social and occupational functioning (Abdel-Baki et al. Reference Abdel-Baki, Ouellet-Plamondon, Salvat, Grar and Potvin2017, Hunt et al. Reference Hunt, Siegfried, Morley, Brooke-Sumner and Cleary2019, Barrowclough et al. Reference Barrowclough, Haddock, Beardmore, Conrod, Craig, Davies, Dunn, Lewis, Moring, Tarrier and Wykes2009, Wade et al. Reference Wade, Harrigan, McGorry, Burgess and Whelan2007), and an increased risk of treatment disengagement (Conus et al. Reference Conus, Lambert, Cotton, Bonsack, McGorry and Schimmelmann2010, Miller et al. Reference Miller, Ream, McCormack, Gunduz-Bruce, Sevy and Robinson2009, Alvarez-Jimenez et al. Reference Alvarez-Jimenez, Priede, Hetrick, Bendall, Killackey, Parker, McGorry and Gleeson2012, Wade et al. Reference Wade, Harrigan, McGorry, Burgess and Whelan2007). Consequently, SUD is a critical focus of early psychosis intervention (Stavely, Reference Stavely2013, sociaux, 2017, Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015).

Expanding the focus to gaming disorder and care model

Given the impact of SUD on FEP outcomes, attention is shifting toward other addictions that may similarly impede recovery. Emerging evidence suggests that individuals with psychotic disorders may be at increased risk for GD, as both conditions frequently emerge during adolescence or early adulthood, disproportionately affect males and are linked to social withdrawal and social anxiety disorders (Hartz et al. Reference Hartz, Pato, Medeiros, Cavazos-Rehg, Sobell, Knowles, Bierut and Pato2014, Roy et al. Reference Roy, Achim, Vallières, Labbé, Mérette, Maziade, Demers and Bouchard2015, Fusar-Poli et al. Reference Fusar-Poli, Tantardini, De Simone, Ramella-Cravaro, Oliver, Kingdon, Kotlicka-Antczak, Valmaggia, Lee, Millan, Galderisi, Balottin, Ricca and McGuire2017b).

Preliminary findings from a longitudinal study in an FEP clinic in Quebec, indicate high gaming engagement in this population, with 37.12% playing video games several times a week, and GD prevalence (7.04%) more than doubling that of the general population (3.03%) (Huot-Lavoie M et al. Reference Huot-Lavoie, Desmeules, Corbeil, Béchard, Brodeur, Essiambre, Thériault, Anderson, Bachand, Haider, Abdel-Baki, Khazaal, Giroux, Demers and Roy2024). GD may complicate FEP presentation, as its core features – social withdrawal and reduced motivation for other activities – mimic negative symptoms of psychosis, potentially leading to under-recognition in clinical settings.

In order to help these patients this paper aims to 1) summarize current knowledge on the co-occurrence of GD and FEP, 2) identify barriers to GDs recognition and management in early psychosis care, and 3) propose strategies for integrating GD assessment and treatment into early psychosis intervention. To achieve this, both GD and SUD literature will be used. Applying lessons from SUD interventions, targeted GD interventions within early psychosis care frameworks may enhance functional outcomes and recovery.

Gaming disorder and psychosis: current evidence

Despite increasing recognition of GD’s clinical implications, research on its co-occurrence with psychotic disorders remains limited. A resent scoping review shows that the available literature only consists of case reports and cross-sectional studies, precluding a definitive establishment of temporality between GD and psychotic disorders, let alone elucidating potential causal mechanisms (Huot-Lavoie et al. Reference Huot-Lavoie, Gabriel-Courval, Béchard, Corbeil, Brodeur and Massé2023). Preliminary evidence suggests a bidirectional relationship, with dynamic fluctuations in both psychotic symptoms and gaming behaviors over time.

Some cases document psychotic episodes coinciding with increased gaming behavior in young adults (Angane et al. Reference Angane, Keshari, Mane and Nayak2021, Rizzo et al. Reference Rizzo, Della Villa and Crisi2015), while others report psychosis onset following abrupt cessation of excessive gaming in the same population (Ghosh & Sarkhel, Reference Ghosh and Sarkhel2018, Paik et al. Reference Paik, Oh and Kim2014), mirroring patterns in SUDs, where both excessive consumption and withdrawal can trigger psychotic episodes (Donoghue et al. Reference Donoghue, Doody, Murray, Jones, Morgan, Dazzan, Hart, Mazzoncini and MacCabe2014, Di Forti et al. Reference Di Forti, Sallis, Allegri, Trotta, Ferraro, Stilo, Marconi, La Cascia, Reis Marques, Pariante, Dazzan, Mondelli, Paparelli, Kolliakou, Prata, Gaughran, David, Morgan, Stahl, Khondoker, MacCabe and Murray2014, Addington & Addington, Reference Addington and Addington2007, Fruensgaard, Reference Fruensgaard1976).

A recent case series by Ricci et al. (Reference Ricci, De Berardis, Maina and Martinotti2023) described two individuals presenting with both psychotic symptoms and GD, in whom antipsychotic treatment led to symptomatic improvement in both conditions (Ricci et al. Reference Ricci, De Berardis, Maina and Martinotti2023). However, larger prospective studies are needed to clarify the nature, directionality, and clinical significance of this interaction.

Potential benefits of video game use

Generational biases, such as “juvenoia,” may contribute to the negative framing of gaming, as emerging technologies and cultural trends are often met with skepticism by older generations (Finkelhor, Reference Finkelhor2011). Discourse surrounding video games frequently emphasizes their addictive potential, yet cultural attitudes toward gaming vary widely. In some societies, particularly those that celebrate e-sports, gaming is regarded as a prestigious and skill-based activity. Acknowledging these diverse perspectives is essential for a balanced consideration of gaming’s potential benefits.

A systematic review reported that therapeutic video game can improve cognitive and social functioning to a degree comparable to established cognitive remediation therapies for psychotic disorders (Quiles & Verdoux, Reference Quiles and Verdoux2023). While promising, the evidence remains methodologically heterogeneous, necessitating further research (Quiles & Verdoux, Reference Quiles and Verdoux2023). Beyond structured interventions, gaming may serve as an adaptive coping strategy for individuals with psychotic disorders. Self-stigma – the internalization of negative societal perceptions of mental illness – is linked to increased social withdrawal, depressive symptoms, and anxiety. One study suggests that video game engagement may mitigate these symptoms in individuals with psychotic disorders experiencing self-stigma (Chang et al. Reference Chang, Chang, Hou, Lin and Griffiths2021).

Preliminary qualitative data suggest that some patients engage in gaming to manage anxiety associated with positive psychotic symptoms (Huot-Lavoie et al. Reference Huot-Lavoie, Béchard, Corbeil, Roy, L’Heureux, Salvini, Lehoux, Essiambre, Thériault, Brodeur, Demers, Khazaal and Roy2025). As one participant described, “During my psychotic episodes, gaming helped me stay focused on a single task, allowing me to ignore what I was hearing or seeing. As soon as I sensed the first signs, like dizziness or voices, I would start playing as a preventive measure.” (Qualitative data from an ongoing study funded by the Canadian Institutes of Health Research (Grant # 509922) and the Fonds de Recherche du Québec – Société et Culture (Grant# 2024-0UER-339171)).

While excessive gaming may precipitate psychotic episodes in some cases, GD may also emerge as an adaptive strategy for coping with self-stigma or symptom regulation. Addressing GD in FEP requires a harm-reduction approach, prioritizing digital well-being over strict abstinence (Vanden Abeele, Reference Vanden Abeele2020).

Challenges in addressing gaming disorder in first-episode psychosis

Early psychosis management prioritize stabilizing psychotic symptoms through pharmacological and psychosocial interventions, often leading to under-recognition of co-occurring conditions like GD. Once acute stabilization is achieved, it is essential to assess and manage comorbidities that may mimic or exacerbate residual symptoms, as this is critical for optimizing recovery (Corbeil et al. Reference Corbeil, Bérubé, Artaud and Roy2021a).

Barriers to engagement in mental health care

Sustained engagement in mental health care remains a significant challenge in addressing GD in FEP. A core feature of psychotic disorders is impaired awareness of illness (Mcevoy et al. Reference Mcevoy, Johnson, Perkins, Lieberman, Hamer, Keefe, Tohen, Glick and Sharma2006, Parellada et al. Reference Parellada, Boada, Fraguas, Reig, Castro-Fornieles, Moreno, Gonzalez-Pinto, Otero, Rapado-Castro, Graell, Baeza and Arango2011, Abdel-Baki et al. Reference Abdel-Baki, Ouellet-Plamondon and Malla2012, Doyle et al. Reference Doyle, Turner, Fanning, Brennan, Renwick, Lawlor and Clarke2014), a difficulty also observed in GD (Jeong et al. Reference Jeong, Yim, Lee, Lee, Potenza, Kwon, Koo, Kweon, Bhang and Choi2018). Whether these awareness deficits are linked or coincidental in patients with both conditions remain unclear, but they complicate structured follow-up and long-term recovery.

Social and environmental factors, including unstable housing and financial insecurity, often take priority, leading to GD being overlooked (Conus et al. Reference Conus, Lambert, Cotton, Bonsack, McGorry and Schimmelmann2010, González-Blanch et al. Reference González-Blanch, Gleeson, Koval, Cotton, McGorry and Alvarez-Jimenez2015). These barriers are particularly pronounced in early psychosis, when functional impairments are most severe (Abdel-Baki et al. Reference Abdel-Baki, Ouellet-Plamondon and Malla2012).

Additionally, substance use is a well-established predictor of treatment disengagement in FEP, further complicating the establishment of stable therapeutic relationship (Stowkowy et al. Reference Stowkowy, Addington, Liu, Hollowell and Addington2012, Doyle et al. Reference Doyle, Turner, Fanning, Brennan, Renwick, Lawlor and Clarke2014). The absence of family involvement has also been linked to higher dropout rates and poorer engagement with mental health services (Doyle et al. Reference Doyle, Turner, Fanning, Brennan, Renwick, Lawlor and Clarke2014, Abdel-Baki et al. Reference Abdel-Baki, Ouellet-Plamondon and Malla2012, Mascayano et al. Reference Mascayano, van der Ven, Martinez-Ales, Henao, Zambrano, Jones, Cabassa, Smith, Yang, Susser and Dixon2021). Family beliefs about mental illness and its treatment play a critical role in shaping patients’ perception of their disorder and motivation to engage in care (Franz et al. Reference Franz, Carter, Leiner, Bergner, Thompson and Compton2010, Lester et al. Reference Lester, Marshall, Jones, Fowler, Amos, Khan and Birchwood2011).

A strong therapeutic alliance is pivotal for treatment adherence (O’Brien et al. Reference O’Brien, Fahmy and Singh2009, Day et al. Reference Day, Bentall, Roberts, Randall, Rogers, Cattell, Healy, Rae and Power2005, Lacro et al. Reference Lacro, Dunn, Dolder, Leckband and Jeste2002). However, establishing this alliance in early psychosis is challenging. Only 14.2% of patients develop a good therapeutic alliance within the first month of treatment, increasing to just 29.8% at six months (Frank & Gunderson, Reference Frank and Gunderson1990). Therefore, prioritizing therapeutic relationship building is essential for mitigating disengagement and supporting long-term recovery (Frank & Gunderson, Reference Frank and Gunderson1990).

Pharmacological treatment challenges in FEP patients

While pharmacological treatments are essential in FEP, they may contribute to the development of behavioral addictions such as GD. Aripiprazole, a third-generation antipsychotic, has been associated with problem gambling, possibly due to its partial agonism at dopamine D3 receptors (Corbeil et al. Reference Corbeil, Corbeil, Dorval, Carmichael, Giroux, Jacques, Demers and Roy2021b, Williams et al. Reference Williams, Lee, Ewah and Neelam2024, Gatto & Aldinio, Reference Gatto and Aldinio2019, Seeman, Reference Seeman2015). Antidepressants and psychostimulants (e.g., amphetamines, methylphenidate), when used in individuals with bipolar or schizoaffective disorder, can precipitate manic episodes, which may potentially present as increased engagement in gaming and gambling (Gitlin, Reference Gitlin2018, Perugi et al. Reference Perugi, Vannucchi, Bedani and Favaretto2017).

Additionally, the striatal dopaminergic blockade induced by antipsychotics may contribute to dysphoria, which is associated with reduced treatment adherence and an increased propensity for substance use – and potentially behavioral addictions – as a form of self-medication (Awad et al. Reference Awad, Hogan, Voruganti and Heslegrave1995, Chue, Reference Chue2006, Trifilieff & Martinez, Reference Trifilieff and Martinez2014, Thompson et al. Reference Thompson, Urban, Slifstein, Xu, Kegeles, Girgis, Beckerman, Harkavy-Friedman, Gil and Abi-Dargham2013, Yakovenko et al. Reference Yakovenko, Clark, Hodgins and Goghari2016).

The use of performance-enhancing substances, primarily stimulant-based, to sustain prolonged gaming sessions is widespread, further exacerbating GD and amplifying associated physical and mental health risks (Burleigh et al. Reference Burleigh, Griffiths, Sumich, Stavropoulos and Kuss2019, Ip et al. Reference Ip, Urbano, Caballero, Lau, Clauson, Torn, Palisoc and Barnett2021, Słyk et al. Reference Słyk, Zarzycki, Grudzień, Majewski, Jasny and Domitrz2023, Ream et al. Reference Ream, Elliott and Dunlap2011, Lakhan & Kirchgessner, Reference Lakhan and Kirchgessner2012).

Given these complexities, a comprehensive approach to GD management in FEP patients must integrate pharmacological considerations, substance misuse, and behavioral addictions to ensure effective and holistic care.

Challenges related to GD diagnosis

A major challenge in diagnosing GD is the low rate of help-seeking within this population. Unlike SUD, where physical signs of intoxication or withdrawal are externally observable, GD lacks overt symptoms, making it less apparent to clinicians and families.

Many individuals experiencing psychological distress may also perceive gaming as more beneficial than professional intervention (van der Schyff et al. Reference van der Schyff, Amon, Ridout, Forsyth and Campbell2023, von der Heiden et al. Reference von der Heiden, Braun, Müller and Egloff2019), while others may conceal problematic gaming behaviors to avoid losing a primary coping strategy (Chang & Lin, Reference Chang and Lin2019, Schneider et al. Reference Schneider, King and Delfabbro2018). Additionally, increased gaming hours have been linked to lower help-seeking efficacy, suggesting that gaming can serve as an avoidant behavior that further deters healthcare engagement (van der Schyff et al. Reference van der Schyff, Amon, Ridout, Forsyth and Campbell2023). GD itself reinforces gaming as a dominant activity, leading individuals to prioritize it over other aspects of daily life, including seeking professional support.

In the context of FEP, these challenges are compounded by existing barriers to care engagement, further complicating GD recognition and treatment. Moreover, negative symptoms such as avolition, anhedonia, and social withdrawal may be attributed solely to psychosis, despite potentially arising from problematic gaming behaviors. This overlap increases the risk of both misdiagnosis and underdiagnosis in early psychosis settings, further delaying appropriate intervention.

Availability and scope of gaming disorder screening tools

Accurately diagnosing GD remains challenging due to its evolving conceptualization. The use of multiple definitions over the years have hindered the establishment of a gold-standard measurement approach, contributing to limited clinician awareness of formal diagnostic guidelines (Castro-Calvo et al. Reference Castro-Calvo, King, Stein, Brand, Carmi, Chamberlain, Demetrovics, Fineberg, Rumpf, Yücel, Achab, Ambekar, Bahar, Blaszczynski, Bowden-Jones, Carbonell, Chan, Ko, de Timary, Dufour, Grall-Bronnec, Lee, Higuchi, Jimenez-Murcia, Király, Kuss, Long, Müller, Pallanti, Potenza, Rahimi-Movaghar, Saunders, Schimmenti, Lee, Siste, Spritzer, Starcevic, Weinstein, Wölfling and Billieux2021, King et al. Reference King, Billieux, Carragher and Delfabbro2020a, King et al. Reference King, Chamberlain, Carragher, Billieux, Stein, Mueller, Potenza, Rumpf, Saunders, Starcevic, Demetrovics, Brand, Lee, Spada, Lindenberg, Wu, Lemenager, Pallesen, Achab, Kyrios, Higuchi, Fineberg and Delfabbro2020b).

While various screening tools exist for assessing gaming behavior (e.g. Internet Gaming Disorder Scale -9 (IGDS9-SF), their applicability for longitudinal follow-up in clinical settings remains underexplored (King et al. Reference King, Chamberlain, Carragher, Billieux, Stein, Mueller, Potenza, Rumpf, Saunders, Starcevic, Demetrovics, Brand, Lee, Spada, Lindenberg, Wu, Lemenager, Pallesen, Achab, Kyrios, Higuchi, Fineberg and Delfabbro2020b). Most GD-specific tools are designed for general populations and do not account for the cognitive and symptomatic features unique to individuals with psychotic disorders (King et al. Reference King, Chamberlain, Carragher, Billieux, Stein, Mueller, Potenza, Rumpf, Saunders, Starcevic, Demetrovics, Brand, Lee, Spada, Lindenberg, Wu, Lemenager, Pallesen, Achab, Kyrios, Higuchi, Fineberg and Delfabbro2020b). Although some instruments align with ICD-11 criteria (Paschke et al. Reference Paschke, Austermann and Thomasius2020, Zhang et al. Reference Zhang, Luo, Hao, Cao, Yuan and Liao2022, Müller et al. Reference Müller, Wegmann, Oelker, Stark, Müller, Montag, Wölfling, Rumpf and Brand2022), they have limited clinical applicability and remain understudied. Critically, no GD measurement scales have been validated for individuals with psychotic disorders, raising concerns about their accuracy and reliability in FEP (Huot-Lavoie et al. Reference Huot-Lavoie, Gabriel-Courval, Béchard, Corbeil, Brodeur and Massé2023).

Cognitive and symptomatic barriers to accurate measurement

Patients with psychotic disorders often experience cognitive impairments, including deficits in working memory, processing speed, executive functioning, and attentional control. These challenges can hinder engagement with standard screening tools, leading to inconsistent or unreliable responses (Barch & Sheffield, Reference Barch and Sheffield2014).

Screening tools like the IGDS9-SF, which require abstract thinking, may be particularly problematic for individuals with psychosis-related cognitive impairments (Zhang et al. Reference Zhang, Li, Stone, Woodberry, Seidman, Tang, Guo, Zhuo, Qian, Cui, Zhu, Jiang, Chow, Tang, Li, Jiang, Yi, Xiao, Wang and van Amelsvoort2015, Müller et al. Reference Müller, Wegmann, Oelker, Stark, Müller, Montag, Wölfling, Rumpf and Brand2022, Zanelli et al. Reference Zanelli, Mollon, Sandin, Morgan, Dazzan, Pilecka, Reis Marques, David, Morgan, Fearon, Doody, Jones, Murray and Reichenberg2019). Simplifying language, providing clear examples, and integrating visual aids could improve comprehension and response accuracy.

An optimal screening tool should also account for impaired awareness of illness and the risk of symptom misattribution between GD and psychotic disorders (e.g., avolition, social withdrawal). Differentiating these overlapping symptoms by assessing them within their specific clinical context would enhance diagnostic precision.

These challenges highlight the urgent need for validated GD screening tools tailored for individual with FEP. Incorporating adaptations that address cognitive deficits, insight-related impairments, and symptoms overlap is essential to improving diagnostic accuracy and ensuring appropriate clinical interventions.

Challenges related to treatment of patient living with both GD and FEP

Systematic reviews on GD treatment consistently identify cognitive–behavioral therapy (CBT) as the most widely implemented approach (Costa and Kuss Reference Costa and Kuss2019, King et al., Reference King, Delfabbro, Wu, Doh, Kuss, Pallesen, Mentzoni, Carragher and Sakuma2017, Lampropoulou et al., Reference Lampropoulou, Siomos, Floros and Christodoulou2022, Stevens et al., Reference Stevens, King, Dorstyn and Delfabbro2019, Xu et al. Reference Xu, Wu, Geng, Wang, Guo, Song, Liu, Deng, Zhang and Potenza2021, Zajac et al., Reference Zajac, Ginley, Chang and Petry2017, Zajac et al., Reference Zajac, Ginley and Chang2020, Khazaal et al., Reference Khazaal, Billieux, Achab, Simon, Dufour and Benyamina2024). Core components often include psychoeducation, increased awareness of internet use, gradual reduction of gaming time, development of cessation strategies, cognitive restructuring to address maladaptive thoughts, and relapse prevention (Torres-Rodríguez et al. Reference Torres-Rodríguez, Griffiths, Carbonell and Oberst2018, Lampropoulou et al., Reference Lampropoulou, Siomos, Floros and Christodoulou2022).

A structured treatment model for problematic internet use, including GD, has been developed and evaluated by Dufour et al. (Reference Dufour2023) in outpatient addiction services (Dufour et al. Reference Dufour2023). This intervention consists of eight key stages: 1) behavioral activation; 2) understanding technology use motivations; 3) enhancing motivation for change; 4) improving control over technology use; 5) emotion regulation; 6) problem-solving; 7) strengthening social relationships; and 8) skill consolidation. The approach adapts CBT principles to GD by addressing in-game cognitive, emotional, and behavioral experiences, reinforcing self-regulation strategies, and identifying relapse-risk situations (Taquet & Hautekeete, Reference Taquet and Hautekeete2013).

Despite these promising treatment models, no intervention has been specifically designed for individuals with psychotic disorders. Adapting existing approaches is crucial to address engagement difficulties, psychotic symptoms – including negative symptoms that limit motivation – and cognitive impairments that may affect adherence and therapeutic outcomes.

What we learned from substance use disorders

Managing co-occurring addictions in individuals with FEP requires nuanced, patient-centered approaches, and empathy. Clinical guidelines for SUD management in FEP provide valuable insights that can inform GD care (Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015, Laboratory, 2019).

Assessment challenge

Substance use assessments are recommended upon admission to early psychosis services (Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015, Laboratory, 2019). However, the acute phase of psychosis is often marked by significant distress and instability, leading patients to underreport or withhold information regarding substance use. Ongoing monitoring beyond initial stabilization is essential to identify emerging addiction patterns and evaluate intervention effectiveness.

Cognitive impairments commonly observed in psychotic disorders pose significant obstacles to accurate assessment. A gradual, paced approach can help mitigate these challenges, allowing patients to process information incrementally. Normalizing hesitation, fostering a safe, trusting environment encourage honest disclosure (Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015).

A multimodal strategy – incorporating standardized screening tools, diagnostic interviews, self-report measures, and collateral information from family members – provides a comprehensive understanding of substance use behaviors. Structured self-monitoring further empowers patients to track usage patterns, recognize triggers, and actively engage in treatment (Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015, Orygen, 2016, Stavely, Reference Stavely2013).

Engagement challenge

While patients may accept antipsychotic treatment, they often remain ambivalent about addressing addictions. The Stage of Change models provide a framework for tailoring interventions based on an individual’s motivational stage and its principles apply equally to behavioral addictions like GD (Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015, Barrowclough et al. Reference Barrowclough, Haddock, Wykes, Beardmore, Conrod, Craig, Davies, Dunn, Eisner, Lewis, Moring, Steel and Tarrier2010).

Telemedicine, brief digital contacts (e.g., text messaging, email), and flexible outreach (e.g., community follow-ups and reminders) can sustain engagement and interdisciplinary coordination (Alameda et al. Reference Alameda, Golay, Baumann, Morandi, Ferrari, Conus and Bonsack2016, D’Arcey et al. Reference D’Arcey, Collaton, Kozloff, Voineskos, Kidd and Foussias2020, Vignapiano et al. Reference Vignapiano, Monaco, Panarello, Landi, Di Gruttola, Malvone, Martiadis, Raffone, Marenna, Pontillo, Di Stefano, D’Angelo, Steardo and Corrivetti2025).

A non-judgmental and empathic approach that normalizes struggles, alongside family involvement when possible, also contribute in reducing stigma and improves treatment adherence and outcomes (Tait et al. Reference Tait, Birchwood and Trower2003, Doyle et al. Reference Doyle, Turner, Fanning, Brennan, Renwick, Lawlor and Clarke2014, Van Dorn et al. Reference Van Dorn, Swanson, Elbogen and Swartz2005, Gaebel et al. Reference Gaebel, Zäske and Baumann2006, Galanis et al. Reference Galanis, Weber, Delfabbro, Billieux and King2023, Hughes et al. Reference Hughes, Crlenjak, Hetrick, Nicoll, Elkins, Cementon and Leceister2015, Orygen, 2016).

Integrating addiction treatment into an early intervention in psychosis program

Managing co-occurring SUD and FEP within fragmented clinical settings is largely ineffective (Mueser & Gingerich, Reference Mueser and Gingerich2013, Ridgely et al. Reference Ridgely, Goldman and Willenbring1990, Laboratory, 2019). Disconnected psychiatric and addiction treatments contribute to poor follow-through on referrals to external services, inadequate communication between care teams, and high dropout rates (Mueser & Gingerich, Reference Mueser and Gingerich2013, Ridgely et al. Reference Ridgely, Goldman and Willenbring1990, Laboratory, 2019). To overcome these barriers, integrated treatment frameworks are essential.

The role of early intervention in psychosis programs

Early intervention in psychosis (EIP) programs are specialized, evidence-based services designed to detect and treat FEP at its earliest stages. EIP teams – comprising psychiatrists, nurses, social workers, occupational therapists, psychologists, and pharmacists – deliver individualized care that integrates both clinical and psychosocial dimensions (Orygen, 2016, Stavely, Reference Stavely2013). By addressing barriers like prolonged duration of untreated psychosis and fragmented service delivery, EIP significantly improves patient trajectories through coordinated multidisciplinary care (Malla et al. Reference Malla, Iyer, McGorry, Cannon, Coughlan, Singh, Jones and Joober2016). Extensive evidence supports the effectiveness of EIP, demonstrating that timely, holistic interventions lead to substantial improvements in clinical outcomes, functional recovery, and overall quality of life (Correll et al. Reference Correll, Galling, Pawar, Krivko, Bonetto, Ruggeri, Craig, Nordentoft, Srihari, Guloksuz, Hui, Chen, Valencia, Juarez, Robinson, Schooler, Brunette, Mueser, Rosenheck, Marcy, Addington, Estroff, Robinson, Penn, Severe and Kane2018).

Incorporating SUD treatment within EIP

Given the high prevalence of SUD in FEP, integrating addiction expertise within EIP programs is becoming standard practice, ensuring the integrate management of both conditions (Laboratory, 2019, Orygen, 2016, sociaux, 2017, Dixon et al. Reference Dixon, Dickerson, Bellack, Bennett, Dickinson, Goldberg, Lehman, Tenhula, Calmes, Pasillas, Peer and Kreyenbuhl2010). Integrated treatment models demonstrate superior outcomes compared to non-integrated approaches. For instance, in integrated care groups, work or school participation increased by 21%, compared to 7% in community-treated groups (McFarlane et al. Reference McFarlane, Levin, Travis, Lucas, Lynch, Verdi, Williams, Adelsheim, Calkins, Carter, Cornblatt, Taylor, Auther, McFarland, Melton, Migliorati, Niendam, Ragland, Sale, Salvador and Spring2015). Integrated care also improves symptom management, functional recovery, and treatment adherence (Fusar-Poli et al. Reference Fusar-Poli, McGorry and Kane2017a).

Drawing from empirical evidence and clinical guidelines, EIP programs must embed addiction treatment as a core component of care, providing comprehensive support for individuals with dual diagnoses.

Integration of GD intervention in EIP programs

Building on insight from managing co-occurring SUD and FEP, there is growing recognition of the need to integrate behavioral addiction interventions, particularly GD, into EIP programs. While integrated care models for SUD have demonstrated clear benefits, the role of GD within this framework remains underexplored. Given its classification as a behavioral addiction and its potential impact on psychosocial functioning, incorporating GD assessment and treatment within EIP programs is both clinically relevant and necessary.

The following section presents a preliminary clinical model for integrating GD management into EIP programs. It outlines specific strategies to address the previously highlighted challenges, enhancing screening, follow-up, and therapeutic engagement, while identifying critical knowledge gaps that must be addressed to optimize care for individuals with both conditions. By adopting a more integrated approach, EIP programs can more effectively meet the needs of patients struggling with both psychotic and behavioral addictions.

Proposed clinical management of GD in EIP programs

This clinical framework builds on existing interventions for SUD in FEP and is informed by clinical and research experiences following the implementation of a GD screening protocol within an ongoing longitudinal study (Huot-Lavoie et al. Reference Huot-Lavoie, Corbeil, Béchard, Brodeur, Desmeules and Thériault2024).

A non-judgmental, patient-centered approach is essential when taking care of individuals with GD and FEP. Early care should prioritize understanding gaming habits, including their personal significance and perceived benefits, to foster engagement and facilitate a nuanced behavioral assessment. Case managers, who maintain continuous patient contact and coordinate care within EIP programs, should play a central role in delivering interventions. Their comprehensive understanding of each patient’s condition enables early detection of problematic gaming behaviors and supports tailored interventions.

Youth-friendly approaches can enhance patient engagement and adherence by aligning treatment environments with younger individuals’ interests and communications styles, ultimately improving treatment participation and outcomes (Orygen, 2016).

Assessment of gaming behavior in EIP

Assessing gaming behavior in patients with FEP extends beyond simply documenting screen time; it provides valuable insight into lifestyle, sleep patterns, and social interactions. Understanding gaming motivations and emotional responses can also reveal preserved emotional engagement, even in patients perceived as anhedonic.

The proposed evaluation consists of three distinct phases. The first two phases are conducted by the case manager, who gathers general information about gaming behaviors and their impact on patient functioning. In the final phase, a psychiatrist reviews the collected data and conducts a formal diagnostic interview based on ICD-11 criteria for GD.

Evaluating gaming habits

This evaluation can unfold through informal discussions alongside routine care coordination, fostering a therapeutic alliance and encouraging honest disclosure.

Key components for a comprehensive evaluation:

  • Frequency and duration of gaming sessions, including daytime and nighttime habits. Clinicians may consider inquiring about objective measures of playtime, such as screen time reports or in-game tracking features, to obtain a more accurate assessment of gaming behavior.

  • Online versus offline gaming and the types of interaction they have with other players (e.g., competitive vs collaborative) providing insights into social interactions within gaming environments.

  • Assessment of gaming motives and perceived benefits of gaming.

  • Engagement in gaming-related activities, such as participation in video game streaming platforms, implication in gaming community and loot box purchases which have been associated with increased GD risk (Raneri et al. Reference Raneri, Montag, Rozgonjuk, Satel and Pontes2022, Cabeza-Ramírez et al. Reference Cabeza-Ramírez, Rey-Carmona, del Carmen Cano-Vicente and Solano-Sánchez2022).

  • Impact of gaming and related activities on academic performance, employment, relationships, health, and overall daily-life functioning.

To ensure accurate responses, clinicians should use clear, straightforward language, considering potential impairments in abstract thinking and cognition in FEP. Questions should also help differentiate excessive gaming from GD.

Sample screening questions:

  • Has gaming delayed your schoolwork or job tasks?

  • How does gaming affect your sleep, health, or mood?

  • Have you had conflicts with family or peers over gaming?

  • What other activities or hobbies do you engage in outside of gaming?

  • Are there activities or hobbies you used to enjoy that you no longer do because of gaming?

  • How does gaming affect your daily schedule or routine?

  • Have you tried to reduce or stop gaming? Why?

  • How do you usually feel when you can’t play video game?

Enhancing precision in gaming behavior assessment

Obtaining collateral feedback from family members and caregivers provides a more comprehensive understanding of gaming behaviors. Questions like “Have you noticed changes in the patient’s behavior related to gaming?” or “Have there been conflicts at home concerning video games?” can uncover discrepancies between the patient’s self-reports and external observations. Additionally, inquiring about the perceived consequences of gaming habits on both the patient and their family and how the patient manages and responds to gaming interruptions can provide a more comprehensive understanding of the patient’s gaming patterns and their overall impact. These discussions also offer an opportunity to highlight positive aspects of gaming, such as social connection or stress relief, while educating families on supporting healthy gaming habits and minimizing stigmatization.

Although screening tools are useful adjuncts, existing instruments lack validation in FEP populations. Although new tools such as the ACSID-11 capture the key components of GD assessment based on ICD-11 criteria, their items may be difficult for patients to answer and often require dedicated time to complete, which poses challenges for individuals facing multiple priorities in early intervention settings. To optimize GD screening in FEP care, the following adaptations are recommended:

  • Simplified Language and Instructions: Clear, concise language enhances comprehension in patients with cognitive impairments.

  • Shortened, Focused Questionnaires: Instruments should be reduced to a minimal set of items that directly reflect ICD-11 diagnostic criteria thereby improving feasibility and response reliability without sacrificing diagnostic precision.

  • Incorporation of Visual Aids: Visual supports (e.g., pictograms, graded color scales) can facilitate understanding and engagement in patients with or attentional difficulties, increasing accuracy of self-reports.

  • Flexible Administration: Allowing breaks or splitting assessments into multiple sessions (e.g., 2 – 3 questions at a time during routine follow-up) to minimize fatigue and maximize participation in early intervention settings.

Frequent reassessments are critical to identifying changes in gaming behaviors and differentiating transient patterns from persistent problematic behaviors. Maintaining a gaming journal can serve as a useful self-monitoring tool for patients, fostering greater insight into gaming habits and supporting behavioral self-regulation.

Conducting a diagnostic interview

Following the initial evaluation and screening, a comprehensive psychiatric diagnostic interview conducted by a psychiatrist is essential. By integrating self-reported data, collateral information, and validated screening tools from the previous assessment stages, clinicians can effectively differentiate between normative, hazardous, and pathological gaming behaviors. This structured approach enhances diagnostic precision and facilitates the development of an individualized, evidence-based treatment plan, tailored to the patient’s specific needs.

Integrating gaming disorder evaluation into patient follow-up

GD evaluations should be integrated into standard care protocols and conducted at regular intervals throughout a patient’s EIP journey. Similar to other addictions, systematic assessments every 3 to 6 months facilitate continuous monitoring, enabling timely identification of problematic behaviors. Gaming habits should also be reassessed during significant life transitions (e.g., loss of employment or enrollment in an academic program) to evaluate their impact on daily functioning. In addition, reassessment is warranted after medication changes, as certain psychotropic agents have been linked to increased vulnerability to addictive behaviors. Embedding GD assessments within routine clinical practice ensures that interventions evolve alongside recovery. The development and validation of GD scales tailored to FEP populations will significantly enhance diagnostic accuracy, support progress monitoring, and guide interventions over time.

Integrating gaming disorder treatment into EIP programs

Building on our clinical experience with the structured treatment model for problematic internet use developed by Dufour et al. (Reference Dufour2023), GD management in FEP requires a flexible, patient-centered approach that prioritizes engagement, motivation, and individualized care. Case managers should deliver adaptable interventions, including home-based care when necessary, while accommodating patient absences and gradually incorporating GD-specific strategies.

The treatment approach should integrate key therapeutic components, such as behavioral activation, understanding technology use motivations, enhancing motivation for change, improving control over technology use, emotion regulation, problem-solving, strengthening social relationships, and skill consolidation.

Although no medication is currently approved specifically for the treatment of GD, several agents have been explored. Systematic reviews suggest potential benefit from bupropion and selective serotonin reuptake inhibitors such as escitalopram, based on their prior use in other behavioral addictions, including compulsive buying and pathological gambling (Lampropoulou et al. Reference Lampropoulou, Siomos, Floros and Christodoulou2022, Greenfield, Reference Greenfield2022, Chang et al. Reference Chang, Chang, Yang and Tzang2022, Zajac et al. Reference Zajac, Ginley and Chang2020). However, available studies are few, with small samples, short treatment durations, and limited randomized controlled trials and notably have not examined patients with psychotic disorders. Consequently, the level of evidence remains low, precluding regulatory approval or the establishment of practice guidelines. Theoretical models also raise the possibility that addictolytic agents such as N-acetylcysteine or naltrexone may target shared neurobiological pathways, but these remain speculative.

In clinical practice, pharmacological strategies for GD are best considered within a multimodal framework that also incorporates psychotherapeutic interventions and the management of psychiatric comorbidities. In the context of FEP, particular attention must be given to the overall medication regimen, as antipsychotics and adjunctive treatments may influence vulnerability to addictive behaviors as described in the Pharmacological Treatment Challenges in FEP Patients section. Regular reassessment of both therapeutic benefits and potential risks is therefore essential to ensure safe and effective integration of GD care within early intervention programs.

The unique context of FEP treatment necessitates aligning GD interventions with the patient’s priorities, introducing them at clinically appropriate moments without overshadowing other urgent treatment needs. Additionally, simplified content, structured sessions, and reinforcement of key concepts over time enhance treatment accessibility and adherence. Group interventions within EIP programs can further normalize gaming discussions, reduce stigma, and provide valuable insight into gaming behaviors. Peer support workers can play a key role in this process by sharing lived experiences and fostering engagement. A harm-reduction approach that emphasizes digital well-being over abstinence may offer more sustainable long-term recovery outcomes (Huot-Lavoie et al. Reference Huot-Lavoie, Béchard, Corbeil, Roy, L’Heureux, Salvini, Lehoux, Essiambre, Thériault, Brodeur, Demers, Khazaal and Roy2025). Embedding GD treatment within EIP programs ensures that gaming behaviors are addressed holistically within psychotic disorder care, promoting viable coping mechanisms and improved psychosocial outcomes.

Conclusion

Integrating a comprehensive GD care model within EIP programs is essential for early identification and intervention, preventing complications that may obscure the clinical presentation of psychosis. A patient-centered approach, embedded within routine care, aligns with recovery-oriented practices and supports individuals in achieving balanced, fulfilling lives.

There is an urgent need for GD screening and treatment models tailored to individuals with FEP. Effective interventions must address the unique cognitive, emotional, and social challenges of this population to ensure accurate identification and optimal management of GD. Developing such models will enhance individual outcomes while expanding our understanding of how behavioral addictions intersect with psychotic disorders.

Recognizing and addressing GD is not only essential for comprehensive care but also represents a cornerstone of modern psychiatry, ensuring that clinical practice remains responsive to the evolving realities of patients’ lives in an increasingly digital world.

Financial support

MHL is also supported by the Frederick Banting and Charles Best Canada Graduate Scholarship Doctoral Awards from the Canadian Institute of Health Research (FID-172598) and by Mitacs Grant (IT34510). The funders played no role in the redaction of this article, and we have no restrictions regarding the submission of this manuscript for publication.

Competing interests

The authors declare none.

Ethical standards

The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committee on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008.

References

Abdel-Baki, A, Ouellet-Plamondon, C and Malla, A (2012). Pharmacotherapy challenges in patients with first-episode psychosis. Journal of Affective Disorders 138, S3S14.10.1016/j.jad.2012.02.029CrossRefGoogle ScholarPubMed
Abdel-Baki, A, Ouellet-Plamondon, C, Salvat, É, Grar, K and Potvin, S (2017). Symptomatic and functional outcomes of substance use disorder persistence 2 years after admission to a first-episode psychosis program. Psychiatry Research 247, 113119.10.1016/j.psychres.2016.11.007CrossRefGoogle ScholarPubMed
Addington, J and Addington, D (2007). Patterns, predictors and impact of substance use in early psychosis: A longitudinal study. Acta Psychiatrica Scandinavica 115, 304309.10.1111/j.1600-0447.2006.00900.xCrossRefGoogle ScholarPubMed
Ahmed, GK, Abdalla, AA, Mohamed, AM, Mohamed, LA and Shamaa, HA (2022). Relation between internet gaming addiction and comorbid psychiatric disorders and emotion avoidance among adolescents: A cross-sectional study. Psychiatry Research 312, 114584.10.1016/j.psychres.2022.114584CrossRefGoogle ScholarPubMed
van Rooij, AJ PhD, Kuss, DJ, Griffiths, MD, Shorter, GW, Schoenmakers, TM and van de Mheen, D (2014). The (co-)occurrence of problematic video gaming, substance use, and psychosocial problems in adolescents. Journal of Behavioral Addictions 3, 157165.10.1556/JBA.3.2014.013CrossRefGoogle ScholarPubMed
Alameda, L, Golay, P, Baumann, P, Morandi, S, Ferrari, C, Conus, P and Bonsack, C (2016). Assertive outreach for “difficult to engage” patients: A useful tool for a subgroup of patients in specialized early psychosis intervention programs. Psychiatry Research 239, 212219.10.1016/j.psychres.2016.03.010CrossRefGoogle ScholarPubMed
Alvarez-Jimenez, M, Priede, A, Hetrick, SE, Bendall, S, Killackey, E, Parker, AG, McGorry, PD and Gleeson, JF (2012). Risk factors for relapse following treatment for first episode psychosis: A systematic review and meta-analysis of longitudinal studies. Schizophrenia Research 139, 116128.10.1016/j.schres.2012.05.007CrossRefGoogle ScholarPubMed
American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5, 5th Edn. Arlington, Va: American Psychiatric Association.Google Scholar
Angane, A, Keshari, P, Mane, A and Nayak, A (2021). Psychosis unmasked by gaming: A case series. Annals of Indian Psychiatry 5, 8992.10.4103/aip.aip_84_20CrossRefGoogle Scholar
Awad, A, Hogan, T, Voruganti, L and Heslegrave, R (1995). Patients’ subjective experiences on antipsychotic medications: Implications for outcome and quality of life. International Clinical Psychopharmacology 10, 123132.Google ScholarPubMed
Baker, A, Hiles, S, Thornton, L, Hides, L and Lubman, D (2012). A systematic review of psychological interventions for excessive alcohol consumption among people with psychotic disorders. Acta Psychiatrica Scandinavica 126, 243255.10.1111/j.1600-0447.2012.01885.xCrossRefGoogle ScholarPubMed
Barch, DM and Sheffield, JM (2014). Cognitive impairments in psychotic disorders: Common mechanisms and measurement. World Psychiatry 13, 224232.10.1002/wps.20145CrossRefGoogle ScholarPubMed
Barrowclough, C, Haddock, G, Beardmore, R, Conrod, P, Craig, T, Davies, L, Dunn, G, Lewis, Sôn, Moring, J, Tarrier, N and Wykes, T (2009). Evaluating integrated MI and CBT for people with psychosis and substance misuse: Recruitment, retention and sample characteristics of the MIDAS trial. Addictive behaviors 34, 859866.10.1016/j.addbeh.2009.03.007CrossRefGoogle ScholarPubMed
Barrowclough, C, Haddock, G, Wykes, T, Beardmore, R, Conrod, P, Craig, T, Davies, L, Dunn, G, Eisner, E, Lewis, S, Moring, J, Steel, C and Tarrier, N (2010). Integrated motivational interviewing and cognitive behavioural therapy for people with psychosis and comorbid substance misuse: Randomised controlled trial. British Medical Journal 341, c6325.10.1136/bmj.c6325CrossRefGoogle ScholarPubMed
Blanchard, JJ, Brown, SA, Horan, WP and Sherwood, AR (2000). Substance use disorders in schizophrenia: Review, integration, and a proposed model. Clinical Psychology Review 20, 207234.10.1016/S0272-7358(99)00033-1CrossRefGoogle Scholar
Burleigh, TL, Griffiths, MD, Sumich, A, Stavropoulos, V and Kuss, DJ (2019). A systematic review of the co-occurrence of gaming disorder and other potentially addictive behaviors. Current Addiction Reports 6, 383401.10.1007/s40429-019-00279-7CrossRefGoogle Scholar
Cabeza-Ramírez, LJ, Rey-Carmona, FJ, del Carmen Cano-Vicente, M and Solano-Sánchez, MÁ. (2022). Analysis of the coexistence of gaming and viewing activities in twitch users and their relationship with pathological gaming: A multilayer perceptron approach. Scientific Reports 12, 7904.10.1038/s41598-022-11985-0CrossRefGoogle ScholarPubMed
Castro-Calvo, J, King, DL, Stein, DJ, Brand, M, Carmi, L, Chamberlain, SR, Demetrovics, Z, Fineberg, NA, Rumpf, HJ, Yücel, M, Achab, S, Ambekar, A, Bahar, N, Blaszczynski, A, Bowden-Jones, H, Carbonell, X, Chan, EML, Ko, CH, de Timary, P, Dufour, M, Grall-Bronnec, M, Lee, HK, Higuchi, S, Jimenez-Murcia, S, Király, O, Kuss, DJ, Long, J, Müller, A, Pallanti, S, Potenza, MN, Rahimi-Movaghar, A, Saunders, JB, Schimmenti, A, Lee, SY, Siste, K, Spritzer, DT, Starcevic, V, Weinstein, AM, Wölfling, K and Billieux, J (2021). Expert appraisal of criteria for assessing gaming disorder: An international Delphi study. Addiction 116, 24632475.10.1111/add.15411CrossRefGoogle ScholarPubMed
Chang, SM and Lin, SSJ (2019). Online gaming motive profiles in late adolescence and the related longitudinal development of stress, depression, and problematic internet use. Computers & Education 135, 123137.10.1016/j.compedu.2019.02.003CrossRefGoogle Scholar
Chang, YH, Chang, KC, Hou, WL, Lin, CY and Griffiths, MD (2021). Internet gaming as a coping method among schizophrenic patients facing psychological distress. Journal of Behavioral Addictions 9, 10221031.10.1556/2006.2020.00081CrossRefGoogle Scholar
Chang, CH, Chang, YC, Yang, L and Tzang, RF (2022). The comparative efficacy of treatments for children and young adults with internet addiction/Internet gaming disorder: An updated meta-analysis. International Journal of Environmental Research and Public Health 19, 2612. https://doi.org/10.3390/ijerph19052612.CrossRefGoogle Scholar
Chue, P (2006). The relationship between patient satisfaction and treatment outcomes in schizophrenia. Journal of Psychopharmacology 20, 3856.10.1177/1359786806071246CrossRefGoogle ScholarPubMed
Conus, P, Lambert, M, Cotton, S, Bonsack, C, McGorry, PD and Schimmelmann, BG (2010). Rate and predictors of service disengagement in an epidemiological first-episode psychosis cohort. Schizophrenia Research 118, 256263.10.1016/j.schres.2010.01.032CrossRefGoogle Scholar
Corbeil, O, Bérubé, FA, Artaud, L and Roy, MA (2021a). Detecting and treating comorbid disorders in first-episode psychosis: A lever for recovery. Santé mentale au Québec 46, 307330.10.7202/1088187arCrossRefGoogle ScholarPubMed
Corbeil, O, Corbeil, S, Dorval, M, Carmichael, PH, Giroux, I, Jacques, C, Demers, MF and Roy, MA (2021b). Problem gambling associated with aripiprazole: A nested case–control study in a first-episode psychosis program. CNS Drugs 35, 461468.10.1007/s40263-021-00801-4CrossRefGoogle Scholar
Correll, CU, Galling, B, Pawar, A, Krivko, A, Bonetto, C, Ruggeri, M, Craig, TJ, Nordentoft, M, Srihari, VH, Guloksuz, S, Hui, CLM, Chen, EYH, Valencia, M, Juarez, F, Robinson, DG, Schooler, NR, Brunette, MF, Mueser, KT, Rosenheck, RA, Marcy, P, Addington, J, Estroff, SE, Robinson, J, Penn, D, Severe, JB and Kane, JM (2018). Comparison of early intervention services vs treatment as usual for early-phase psychosis: A systematic review, meta-analysis, and meta-regression. JAMA Psychiatry 75, 555565.10.1001/jamapsychiatry.2018.0623CrossRefGoogle ScholarPubMed
Costa, S and Kuss, DJ (2019). Current diagnostic procedures and interventions for gaming disorders: A systematic review. Frontiers in Psychology 10, 578.10.3389/fpsyg.2019.00578CrossRefGoogle ScholarPubMed
D’Arcey, J, Collaton, J, Kozloff, N, Voineskos, AN, Kidd, SA and Foussias, G (2020). The use of text messaging to improve clinical engagement for individuals with psychosis: systematic review. JMIR Mental Health 7, e16993.10.2196/16993CrossRefGoogle ScholarPubMed
Day, JC, Bentall, RP, Roberts, C, Randall, F, Rogers, A, Cattell, D, Healy, D, Rae, P and Power, C (2005). Attitudes toward antipsychotic medication: The impact of clinical variables and relationships with health professionals. Archives of General Psychiatry 62, 717724.10.1001/archpsyc.62.7.717CrossRefGoogle ScholarPubMed
Di Forti, M, Sallis, H, Allegri, F, Trotta, A, Ferraro, L, Stilo, SA, Marconi, A, La Cascia, C, Reis Marques, T, Pariante, C, Dazzan, P, Mondelli, V, Paparelli, A, Kolliakou, A, Prata, D, Gaughran, F, David, AS, Morgan, C, Stahl, D, Khondoker, M, MacCabe, JH and Murray, RM (2014). Daily use, especially of high-potency cannabis, drives the earlier onset of psychosis in cannabis users. Schizophrenia Bulletin 40, 15091517.10.1093/schbul/sbt181CrossRefGoogle ScholarPubMed
Dixon, LB, Dickerson, F, Bellack, AS, Bennett, M, Dickinson, D, Goldberg, RW, Lehman, A, Tenhula, WN, Calmes, C, Pasillas, RM, Peer, J and Kreyenbuhl, J (2010). The 2009 schizophrenia PORT psychosocial treatment recommendations and summary statements. Schizophrenia Bulletin 36, 4870.10.1093/schbul/sbp115CrossRefGoogle ScholarPubMed
Donoghue, K, Doody, GA, Murray, RM, Jones, PB, Morgan, C, Dazzan, P, Hart, J, Mazzoncini, R and MacCabe, JH (2014). Cannabis use, gender and age of onset of schizophrenia: Data from the AESOP study. Psychiatry Research 215, 528532.10.1016/j.psychres.2013.12.038CrossRefGoogle ScholarPubMed
Doyle, R, Turner, N, Fanning, F, Brennan, D, Renwick, L, Lawlor, E and Clarke, M (2014). First-episode psychosis and disengagement from treatment: A systematic review. Psychiatric Services 65, 603611.10.1176/appi.ps.201200570CrossRefGoogle ScholarPubMed
Dufour, M, et al. (2023). Virtu-A : intervention manualisée pour les jeunes de 15 à 25 ans aux prises avec une utilisation problématique d’Internet - Version 2.0. Université du Québec à Montréal. Google Scholar
Finkelhor, D (2011). The internet, youth safety and the problem of “Juvenoia”. Crimes against children research center. Available at: http://www.unh.edu/ccrc/pdf/Juvenoia%20paper.pdf.Google Scholar
Foti, DJ, Kotov, R, Guey, LT and Bromet, EJ (2010). Cannabis use and the course of schizophrenia: 10-year follow-up after first hospitalization. American Journal of Psychiatry 167, 987993.10.1176/appi.ajp.2010.09020189CrossRefGoogle ScholarPubMed
Frank, AF and Gunderson, JG (1990). The role of the therapeutic alliance in the treatment of schizophrenia: Relationship to course and outcome. Archives of General Psychiatry 47, 228236.10.1001/archpsyc.1990.01810150028006CrossRefGoogle ScholarPubMed
Franz, L, Carter, T, Leiner, AS, Bergner, E, Thompson, NJ and Compton, MT (2010). Stigma and treatment delay in first-episode psychosis: A grounded theory study. Early Intervention in Psychiatry 4, 4756.10.1111/j.1751-7893.2009.00155.xCrossRefGoogle ScholarPubMed
Fruensgaard, K (1976). Withdrawal psychosis: A study of 30 consecutive cases. Acta Psychiatrica Scandinavica 53, 105118.10.1111/j.1600-0447.1976.tb00065.xCrossRefGoogle ScholarPubMed
Fusar-Poli, P, McGorry, PD and Kane, JM (2017a). Improving outcomes of first-episode psychosis: An overview. World Psychiatry 16, 251265.10.1002/wps.20446CrossRefGoogle ScholarPubMed
Fusar-Poli, P, Tantardini, M, De Simone, S, Ramella-Cravaro, V, Oliver, D, Kingdon, J, Kotlicka-Antczak, M, Valmaggia, L, Lee, J, Millan, MJ, Galderisi, S, Balottin, U, Ricca, V and McGuire, P (2017b). Deconstructing vulnerability for psychosis: Meta-analysis of environmental risk factors for psychosis in subjects at ultra high-risk. European Psychiatry 40, 6575.10.1016/j.eurpsy.2016.09.003CrossRefGoogle ScholarPubMed
Gaebel, W, Zäske, H and Baumann, AE (2006). The relationship between mental illness severity and stigma. Acta Psychiatrica Scandinavica 113, 4145.10.1111/j.1600-0447.2005.00716.xCrossRefGoogle Scholar
Galanis, C, Weber, N, Delfabbro, P, Billieux, J and King, D (2023). Gaming disorder and stigma-related judgements of gaming individuals: An online randomized controlled trial. Addiction 118, 16871698.10.1111/add.16211CrossRefGoogle ScholarPubMed
Gatto, EM and Aldinio, V (2019). Impulse control disorders in Parkinson’s disease. A brief and comprehensive review. Frontiers in Neurology 10, 351.10.3389/fneur.2019.00351CrossRefGoogle ScholarPubMed
Ghosh, P and Sarkhel, S (2018). Internet gaming addiction presenting as withdrawal psychosis: An unusual case report. Indian Journal of Private Psychiatry 12, 3437.10.5005/jp-journals-10067-0017CrossRefGoogle Scholar
Gitlin, MJ (2018). Antidepressants in bipolar depression: An enduring controversy. International Journal of Bipolar Disorders 6, 17.10.1186/s40345-018-0133-9CrossRefGoogle ScholarPubMed
González-Blanch, C, Gleeson, JF, Koval, P, Cotton, SM, McGorry, PD and Alvarez-Jimenez, M (2015). Social functioning trajectories of young first-episode psychosis patients with and without cannabis misuse: A 30-month follow-up study. PLoS One 10, e0122404.10.1371/journal.pone.0122404CrossRefGoogle ScholarPubMed
González-Bueso, V, Santamaría, JJ, Fernández, D, Merino, L, Montero, E and Ribas, J (2018). Association between internet gaming disorder or pathological video-game use and comorbid psychopathology: A comprehensive review. International Journal of Environmental Research and Public Health 15, 668.10.3390/ijerph15040668CrossRefGoogle ScholarPubMed
Gonzalez-Pinto, A, Alberich, S, Barbeito, S, Gutierrez, M, Vega, P, Ibanez, B, Haidar, MK, Vieta, E and Arango, C (2011). Cannabis and first-episode psychosis: Different long-term outcomes depending on continued or discontinued use. Schizophrenia Bulletin 37, 631639.10.1093/schbul/sbp126CrossRefGoogle ScholarPubMed
Granic, I, Lobel, A and Engels, RC (2014). The benefits of playing video games. American Psychologist 69, 66.10.1037/a0034857CrossRefGoogle ScholarPubMed
Greenfield, DN (2022). Clinical considerations in internet and video game addiction treatment. Child and Adolescent Psychiatric Clinics of North America 31, 99119.10.1016/j.chc.2021.09.003CrossRefGoogle ScholarPubMed
Hansen, HG, Speyer, H, Starzer, M, Albert, N, Hjorthøj, C, Eplov, LF and Nordentoft, M (2023). Clinical recovery among individuals with a first-episode schizophrenia an updated systematic review and meta-analysis. Schizophrenia Bulletin 49, 297308.10.1093/schbul/sbac103CrossRefGoogle ScholarPubMed
Harrison, I, Joyce, E, Mutsatsa, S, Hutton, S, Huddy, V, Kapasi, M and Barnes, TRE (2008). Naturalistic follow-up of co-morbid substance use in schizophrenia: The West London first-episode study. Psychological Medicine 38, 7988.10.1017/S0033291707000797CrossRefGoogle ScholarPubMed
Hartz, SM, Pato, CN, Medeiros, H, Cavazos-Rehg, P, Sobell, JL, Knowles, JA, Bierut, LJ and Pato, MT (2014). Comorbidity of severe psychotic disorders with measures of substance use. JAMA Psychiatry 71, 248254.10.1001/jamapsychiatry.2013.3726CrossRefGoogle ScholarPubMed
Hughes, ASR, Crlenjak, C, Hetrick, S, Nicoll, M, Elkins, K, Cementon, E and Leceister, S (2015). A matter of substance: working with substance use in early psychosis. Orygen, The National Centre of Excellence in Youth Mental Health.Google Scholar
Hunt, GE, Siegfried, N, Morley, K, Brooke-Sumner, C and Cleary, M (2019). Psychosocial interventions for people with both severe mental illness and substance misuse. Cochrane Database of Systematic Reviews, 12(12), CD001088. https://doi.org/10.1002/14651858.CD001088.pub4 Google ScholarPubMed
Huot-Lavoie, M, Corbeil, O, Béchard, L, Brodeur, S, Desmeules, C, Thériault, C, et al. (2024). First-episode psychosis and gaming disorder: Improving screening and patient’s recovery. In: 9th International Conference on Behavioral Addictions, Gibraltar: Journal of Behavioral Addictions.Google Scholar
Huot-Lavoie, M, Gabriel-Courval, M, Béchard, L, Corbeil, O, Brodeur, S, Massé, C, et al. (2023). Gaming disorder and psychotic disorders: A scoping review. Psychopathology, 56(4), 315323. https://doi.org/10.1159/000527143 CrossRefGoogle ScholarPubMed
Huot-Lavoie, M, Béchard, L, Corbeil, O, Roy, O, L’Heureux, S, Salvini, I, Lehoux, C, Essiambre, AM, Thériault, C, Brodeur, S, Demers, MF, Khazaal, Y and Roy, MA (2025). Lived experience of gaming disorder among people with psychotic disorders: Implications for tailored interventions and clinical management. Current Opinion in Psychiatry 38, 295301.10.1097/YCO.0000000000001013CrossRefGoogle ScholarPubMed
Huot-Lavoie, M, Desmeules, C, Corbeil, O, Béchard, L, Brodeur, S, Essiambre, AM, Thériault, C, Anderson, E, Bachand, L, Haider, ZAA, Abdel-Baki, A, Khazaal, Y, Giroux, I, Demers, MF and Roy, MA (2024). Impact of gaming disorder on first episode psychosis patients’ evolution: Protocol for a multicentered prospective study. Early Intervention in Psychiatry 18, 439445.10.1111/eip.13482CrossRefGoogle ScholarPubMed
Hygen, BW, Skalicka, V, Stenseng, F, Belsky, J, Steinsbekk, S and Wichstrom, L (2020). The co-occurrence between symptoms of internet gaming disorder and psychiatric disorders in childhood and adolescence: Prospective relations or common causes? Journal of Child Psychology and Psychiatry 61, 890898.10.1111/jcpp.13289CrossRefGoogle ScholarPubMed
Ip, EJ, Urbano, EPT, Caballero, J, Lau, WB, Clauson, KA, Torn, RA, Palisoc, AJL and Barnett, MJ (2021). The video gamer 500: Performance-enhancing drug use and internet gaming disorder among adult video gamers. Computers in Human Behavior 123, 106890.10.1016/j.chb.2021.106890CrossRefGoogle Scholar
Jeong, H, Yim, HW, Lee, SY, Lee, HK, Potenza, MN, Kwon, JH, Koo, HJ, Kweon, YS, Bhang, SY and Choi, JS (2018). Discordance between self-report and clinical diagnosis of internet gaming disorder in adolescents. Scientific Reports 8, 10084.10.1038/s41598-018-28478-8CrossRefGoogle ScholarPubMed
Ji, Y, Yin, MXC, Zhang, AY, Wong, DFK (2022). Risk and protective factors of internet gaming disorder among Chinese people: A meta-analysis. Australian & New Zealand Journal of Psychiatry 56, 332346.10.1177/00048674211025703CrossRefGoogle ScholarPubMed
Khazaal, Y, Billieux, J, Achab, S, Simon, O, Dufour, M and Benyamina, A (2024). Trouble du Jeu Vidéo: L’essentiel. RMS éditions. Auteur: Khazaal Yasser Billieux Joël Achab Sophia Simon Olivier Dufour Magali Benyamina Amine Potenza M. Éditeur: RMS Editions ISBN 9782880495411 Collection L’essentiel Nombre de pages 200 Parution 5 déc. 2024 Thème Psychiatrie Type de livre Ouvrage collectifGoogle Scholar
Kim, HS, Son, G, Roh, EB, Ahn, WY, Kim, J, Shin, SH, Chey, J and Choi, KH (2022). Prevalence of gaming disorder: A meta-analysis. Addictive Behaviors 126, 107183.10.1016/j.addbeh.2021.107183CrossRefGoogle ScholarPubMed
King, DL, Billieux, J, Carragher, N and Delfabbro, PH (2020a). Face validity evaluation of screening tools for gaming disorder: Scope, language, and overpathologizing issues. Journal of Behavioral Addictions 9, 113.10.1556/2006.2020.00001CrossRefGoogle ScholarPubMed
King, DL, Chamberlain, SR, Carragher, N, Billieux, J, Stein, D, Mueller, K, Potenza, MN, Rumpf, HJ, Saunders, J, Starcevic, V, Demetrovics, Z, Brand, M, Lee, HK, Spada, M, Lindenberg, K, Wu, AMS, Lemenager, T, Pallesen, S, Achab, S, Kyrios, M, Higuchi, S, Fineberg, NA and Delfabbro, PH (2020b). Screening and assessment tools for gaming disorder: A comprehensive systematic review. Clinical Psychology Review 77, 101831.10.1016/j.cpr.2020.101831CrossRefGoogle ScholarPubMed
King, DL, Delfabbro, PH, Wu, AMS, Doh, YY, Kuss, DJ, Pallesen, Såle, Mentzoni, R, Carragher, N, Sakuma, H (2017). Treatment of internet gaming disorder: An international systematic review and CONSORT evaluation. Clinical Psychology Review 54, 123133.10.1016/j.cpr.2017.04.002CrossRefGoogle ScholarPubMed
Laboratory NMHaSUP (2019). First-Episode Psychosis and Co-Occurring Substance Use Disorders. Publication. In: Administration SAaMHS (ed.). Rockville, MD.Google Scholar
Lacro, JP, Dunn, LB, Dolder, CR, Leckband, SG and Jeste, DV (2002). Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: A comprehensive review of recent literature. The Journal of Clinical Psychiatry 63, 15489.10.4088/JCP.v63n1007CrossRefGoogle ScholarPubMed
Lakhan, SE and Kirchgessner, A (2012). Prescription stimulants in individuals with and without attention deficit hyperactivity disorder: Misuse, cognitive impact, and adverse effects. Brain and Behavior 2, 661677.10.1002/brb3.78CrossRefGoogle ScholarPubMed
Lambert, M, Conus, P, Lubman, DI, Wade, D, Yuen, H, Moritz, S, Naber, D, McGorry, PD and Schimmelmann, BG (2005). The impact of substance use disorders on clinical outcome in 643 patients with first-episode psychosis. Acta Psychiatrica Scandinavica 112, 141148.10.1111/j.1600-0447.2005.00554.xCrossRefGoogle ScholarPubMed
Lampropoulou, P, Siomos, K, Floros, G and Christodoulou, N (2022). Effectiveness of available treatments for gaming disorders in children and adolescents: A systematic review. Cyberpsychology, Behavior, and Social Networking 25, 513.10.1089/cyber.2021.0067CrossRefGoogle ScholarPubMed
Lee, J, Bae, S, Kim, BN and Han, DH (2021). Impact of attention-deficit/hyperactivity disorder comorbidity on longitudinal course in internet gaming disorder: A 3-year clinical cohort study. Journal of Child Psychology and Psychiatry 62, 11101119.10.1111/jcpp.13380CrossRefGoogle ScholarPubMed
Lehoux, C, Lefebvre, AA, Maziade, M, Roy, MA and Gobeil, MH (2009). The five-factor structure of the PANSS: A critical review of its consistency across studies. Clinical Schizophrenia and Related Psychoses 3, 103110.10.3371/CSRP.3.2.5CrossRefGoogle Scholar
Lester, H, Marshall, M, Jones, P, Fowler, D, Amos, T, Khan, N and Birchwood, M (2011). Views of young people in early intervention services for first-episode psychosis in England. Psychiatric Services 62, 882887.10.1176/ps.62.8.pss6208_0882CrossRefGoogle ScholarPubMed
Linszen, D and van Amelsvoort, T (2007). Cannabis and psychosis: An update on course and biological plausible mechanisms. Current Opinion in Psychiatry 20, 116120.10.1097/YCO.0b013e32803577fbCrossRefGoogle ScholarPubMed
Malhi, G, Adams, D, Moss, B and Walter, G (2010). To medicate or not to medicate, when diagnosis is in question: Decision-making in first episode psychosis. Australasian Psychiatry 18, 230237.10.3109/10398560903358846CrossRefGoogle ScholarPubMed
Malla, A, Iyer, S, McGorry, P, Cannon, M, Coughlan, H, Singh, S, Jones, P and Joober, R (2016). From early intervention in psychosis to youth mental health reform: A review of the evolution and transformation of mental health services for young people. Social Psychiatry and Psychiatric Epidemiology 51, 319326.10.1007/s00127-015-1165-4CrossRefGoogle ScholarPubMed
Malla, A, Norman, R, Bechard-Evans, L, Schmitz, N, Manchanda, R and Cassidy, C (2008). Factors influencing relapse during a 2-year follow-up of first-episode psychosis in a specialized early intervention service. Psychological Medicine 38, 15851593.10.1017/S0033291707002656CrossRefGoogle Scholar
Marshall, M, Lewis, S, Lockwood, A, Drake, R, Jones, P and Croudace, T (2005). Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: A systematic review. Archives of General Psychiatry 62, 975983.10.1001/archpsyc.62.9.975CrossRefGoogle ScholarPubMed
Mascayano, F, van der Ven, E, Martinez-Ales, G, Henao, AR, Zambrano, J, Jones, N, Cabassa, LJ, Smith, TE, Yang, LH, Susser, E and Dixon, LB (2021). Disengagement from early intervention services for psychosis: A systematic review. Psychiatric Services 72, 4960.10.1176/appi.ps.201900375CrossRefGoogle ScholarPubMed
Mcevoy, JP, Johnson, J, Perkins, D, Lieberman, JA, Hamer, RM, Keefe, RS, Tohen, M, Glick, ID and Sharma, T (2006). Insight in first-episode psychosis. Psychological Medicine 36, 13851393.10.1017/S0033291706007793CrossRefGoogle ScholarPubMed
McFarlane, WR, Levin, B, Travis, L, Lucas, FL, Lynch, S, Verdi, M, Williams, D, Adelsheim, S, Calkins, R, Carter, CS, Cornblatt, B, Taylor, SF, Auther, AM, McFarland, B, Melton, R, Migliorati, M, Niendam, T, Ragland, JD, Sale, T, Salvador, M and Spring, E (2015). Clinical and functional outcomes after 2 years in the early detection and intervention for the prevention of psychosis multisite effectiveness trial. Schizophrenia Bulletin 41, 3043.10.1093/schbul/sbu108CrossRefGoogle ScholarPubMed
Miller, R, Ream, G, McCormack, J, Gunduz-Bruce, H, Sevy, S and Robinson, D (2009). A prospective study of cannabis use as a risk factor for non-adherence and treatment dropout in first-episode schizophrenia. Schizophrenia Research 113, 138144.10.1016/j.schres.2009.04.018CrossRefGoogle ScholarPubMed
Mueser, KT and Gingerich, S (2013). Treatment of co-occurring psychotic and substance use disorders. Social Work in Public Health 28, 424439.10.1080/19371918.2013.774676CrossRefGoogle ScholarPubMed
Müller, SM, Wegmann, E, Oelker, A, Stark, R, Müller, A, Montag, C, Wölfling, K, Rumpf, HJ, and Brand, M (2022). Assessment of criteria for specific internet-use disorders (ACSID-11): Introduction of a new screening instrument capturing ICD-11 criteria for gaming disorder and other potential internet-use disorders. Journal of Behavioral Addictions 11, 427450.Google ScholarPubMed
O’Brien, A, Fahmy, R and Singh, SP (2009). Disengagement from mental health services. A literature review. Social Psychiatry and Psychiatric Epidemiology 44, 558568.10.1007/s00127-008-0476-0CrossRefGoogle ScholarPubMed
Orygen TNCoEiYMH (2016). Early psychosis guidelines writing group and EPPIC national support program, Australian clinical guidelines for early psychosis.Google Scholar
Paik, A, Oh, D and Kim, D (2014). A case of withdrawal psychosis from internet addiction disorder. Psychiatry Investigation 11, 207209.10.4306/pi.2014.11.2.207CrossRefGoogle ScholarPubMed
Parellada, M, Boada, L, Fraguas, D, Reig, S, Castro-Fornieles, J, Moreno, D, Gonzalez-Pinto, A, Otero, S, Rapado-Castro, M, Graell, M, Baeza, I and Arango, C (2011). Trait and state attributes of insight in first episodes of early-onset schizophrenia and other psychoses: A 2-year longitudinal study. Schizophrenia Bulletin 37, 3851.10.1093/schbul/sbq109CrossRefGoogle ScholarPubMed
Paschke, K, Austermann, MI and Thomasius, R (2020). Assessing ICD-11 gaming disorder in adolescent gamers: Development and validation of the gaming disorder scale for adolescents (GADIS-A). Journal of Clinical Medicine 9, 993. https://doi.org/10.3390/jcm9040993 CrossRefGoogle ScholarPubMed
Perkins, DO, Gu, H, Boteva, K and Lieberman, JA (2005). Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: A critical review and meta-analysis. American Journal of Psychiatry 162, 17851804.10.1176/appi.ajp.162.10.1785CrossRefGoogle ScholarPubMed
Perugi, G, Vannucchi, G, Bedani, F and Favaretto, E (2017). Use of stimulants in bipolar disorder. Current Psychiatry Reports 19, 19.10.1007/s11920-017-0758-xCrossRefGoogle ScholarPubMed
Quiles, C and Verdoux, H (2023). Benefits of video games for people with schizophrenia: A literature review. Current Opinion in Psychiatry 36, 184193.10.1097/YCO.0000000000000867CrossRefGoogle ScholarPubMed
Raneri, PC, Montag, C, Rozgonjuk, D, Satel, J and Pontes, HM (2022). The role of microtransactions in internet gaming disorder and gambling disorder: A preregistered systematic review. Addictive Behaviors Reports 15, 100415.10.1016/j.abrep.2022.100415CrossRefGoogle ScholarPubMed
Ream, GL, Elliott, LC and Dunlap, E (2011). Playing video games while using or feeling the effects of substances: Associations with substance use problems. International Journal of Environmental Research and Public Health 8, 39793998.10.3390/ijerph8103979CrossRefGoogle ScholarPubMed
Ricci, V, De Berardis, D, Maina, G and Martinotti, G (2023). Internet gaming disorders and early onset psychosis in young people: A case study and clinical observations. International Journal of Environmental Research and Public Health 20, 3920.10.3390/ijerph20053920CrossRefGoogle Scholar
Richard, J, Temcheff, CE and Derevensky, JL (2020). Gaming disorder across the lifespan: A scoping review of longitudinal studies. Current Addiction Reports 7, 561587.10.1007/s40429-020-00339-3CrossRefGoogle Scholar
Ridgely, MS, Goldman, HH and Willenbring, M (1990). Barriers to the care of persons with dual diagnoses: Organizational and financing issues. Schizophrenia Bulletin 16, 123132.10.1093/schbul/16.1.123CrossRefGoogle Scholar
Rizzo, A, Della Villa, L and Crisi, A (2015). Can the problematic internet use evolve in a pre-psychotic state? A single case study with the Wartegg. Computers in Human Behavior 51, 532538.10.1016/j.chb.2015.04.063CrossRefGoogle Scholar
Robinson, DG, Woerner, MG, McMeniman, M, Mendelowitz, A and Bilder, RM (2004). Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder. American Journal of Psychiatry 161, 473479.10.1176/appi.ajp.161.3.473CrossRefGoogle ScholarPubMed
Roy, MA, Achim, AM, Vallières, C, Labbé, A, Mérette, C, Maziade, M, Demers, MF, and Bouchard, RH (2015). Comorbidity between anxiety disorders and recent-onset psychotic disorders. Schizophrenia Research 166, 353354.10.1016/j.schres.2015.04.041CrossRefGoogle ScholarPubMed
Roy, MA, Cellard, C, Côté, ME, Demers, MF, Lehoux, C, Menear, M, Morin, MH, Péloquin, S and Vigneault, L (2024). Modèle intégré d’une approche de soins axée sur le rétablissement. Le Journal de l’AMPQ. (Hiver)Google Scholar
Rygaard Hjorthoj, C, Baker, A, Fohlmann, A and Nordentoft, M (2014). Intervention efficacy in trials targeting cannabis use disorders in patients with comorbid psychosis systematic review and meta-analysis. Current Pharmaceutical Design 20, 22052211.10.2174/13816128113199990431CrossRefGoogle ScholarPubMed
Sara, GE, Burgess, PM, Malhi, GS, Whiteford, HA and Hall, WC (2014). Stimulant and other substance use disorders in schizophrenia: Prevalence, correlates and impacts in a population sample. Australian & New Zealand Journal of Psychiatry 48, 10361047.10.1177/0004867414533838CrossRefGoogle Scholar
Schneider, LA, King, DL and Delfabbro, PH (2018). Maladaptive coping styles in adolescents with internet gaming disorder symptoms. International Journal of Mental Health and Addiction 16, 905916. https://api.semanticscholar.org/CorpusID:34458030 10.1007/s11469-017-9756-9CrossRefGoogle Scholar
Seeman, P (2015). Parkinson’s disease treatment may cause impulse-control disorder via dopamine D3 receptors. Synapse 69, 183189.10.1002/syn.21805CrossRefGoogle ScholarPubMed
Słyk, S, Zarzycki, M, Grudzień, K, Majewski, G, Jasny, M and Domitrz, I (2023). The Prevalence and Outlook of Doping in Electronic Sports (Esports): An original study and review of the overlooked medical challenges. Cureus 15, e48490.Google ScholarPubMed
sociaux MdlSedS (2017). Cadre de référence : Programmes d’interventions pour premiers épisodes psychotiques (PPEP). In: Québec Gd (ed.).Google Scholar
Sorbara, F, Liraud, F, Assens, F, Abalan, F and Verdoux, H (2003). Substance use and the course of early psychosis: A 2-year follow-up of first-admitted subjects. European Psychiatry 18, 133136.10.1016/S0924-9338(03)00027-0CrossRefGoogle ScholarPubMed
Stavely, H (2013). Eppic model & service implementation. Orygen Youth Health Research Centre.Google Scholar
Stevens, MW, King, DL, Dorstyn, D and Delfabbro, PH (2019). Cognitive–behavioral therapy for internet gaming disorder: A systematic review and meta-analysis. Clinical Psychology & Psychotherapy 26, 191203.10.1002/cpp.2341CrossRefGoogle ScholarPubMed
Stowkowy, J, Addington, D, Liu, L, Hollowell, B and Addington, J (2012). Predictors of disengagement from treatment in an early psychosis program. Schizophrenia Research 136, 712.10.1016/j.schres.2012.01.027CrossRefGoogle Scholar
Tait, L, Birchwood, M and Trower, P (2003). Predicting engagement with services for psychosis: Insight, symptoms and recovery style. British Journal of Psychiatry 182, 123128.10.1192/bjp.182.2.123CrossRefGoogle ScholarPubMed
Taquet, P and Hautekeete, M (2013). Prise en charge TCC d’une addiction aux jeux vidéo: l’expérience de jeu contribue à la thérapie. Journal de Thérapie Comportementale et Cognitive 23, 102112.10.1016/j.jtcc.2013.06.001CrossRefGoogle Scholar
Thoma, P and Daum, I (2013). Comorbid substance use disorder in schizophrenia: A selective overview of neurobiological and cognitive underpinnings. Psychiatry and Clinical Neurosciences 67, 367383.10.1111/pcn.12072CrossRefGoogle ScholarPubMed
Thompson, JL, Urban, N, Slifstein, M, Xu, X, Kegeles, LS, Girgis, RR, Beckerman, Y, Harkavy-Friedman, JM, Gil, R and Abi-Dargham, A (2013). Striatal dopamine release in schizophrenia comorbid with substance dependence. Molecular Psychiatry 18, 909915.10.1038/mp.2012.109CrossRefGoogle ScholarPubMed
Torres-Rodríguez, A, Griffiths, MD, Carbonell, X and Oberst, U (2018). Treatment efficacy of a specialized psychotherapy program for internet gaming disorder. Journal of Behavioral Addictions 7, 939952.10.1556/2006.7.2018.111CrossRefGoogle ScholarPubMed
Trifilieff, P and Martinez, D (2014). Blunted dopamine release as a biomarker for vulnerability for substance use disorders. Biological Psychiatry 76, 45.10.1016/j.biopsych.2014.04.017CrossRefGoogle ScholarPubMed
van der Schyff, EL, Amon, KL, Ridout, B, Forsyth, R, Campbell, AJ (2023). Mental health help-seeking behavior of male video game players: An online survey. Cyberpsychology, Behavior, and Social Networking 26, 717723.10.1089/cyber.2023.0035CrossRefGoogle ScholarPubMed
Van Dorn, RA, Swanson, JW, Elbogen, EB and Swartz, MS (2005). A comparison of stigmatizing attitudes toward persons with schizophrenia in four stakeholder groups: Perceived likelihood of violence and desire for social distance. Psychiatry 68, 152163.10.1521/psyc.2005.68.2.152CrossRefGoogle ScholarPubMed
Vanden Abeele, MMP (2020). Digital wellbeing as a dynamic construct. Communication Theory 31, 932955.10.1093/ct/qtaa024CrossRefGoogle Scholar
Vignapiano, A, Monaco, F, Panarello, E, Landi, S, Di Gruttola, B, Malvone, R, Martiadis, V, Raffone, F, Marenna, A, Pontillo, M, Di Stefano, V, D’Angelo, M, Steardo, L Jr. and Corrivetti, G (2025). Digital interventions for the rehabilitation of first-episode psychosis: An integrated perspective. Brain Sciences 15, 80. https://doi.org/10.3390/brainsci15010080 CrossRefGoogle ScholarPubMed
Volkow, ND (2009). Substance use disorders in schizophrenia--clinical implications of comorbidity. Schizophr Bull 35(3) 469472. https://doi.org/10.1093/schbul/sbp016 CrossRefGoogle ScholarPubMed
von der Heiden, JM, Braun, B, Müller, KW and Egloff, B (2019). The association between video gaming and psychological functioning. Frontiers in Psychology 10, 1731. https://doi.org/10.3389/fpsyg.2019.01731 CrossRefGoogle ScholarPubMed
Wade, D, Harrigan, S, Edwards, J, Burgess, PM, Whelan, G and McGorry, PD (2006). Substance misuse in first-episode psychosis: 15-month prospective follow-up study. British Journal of Psychiatry 189, 229234.10.1192/bjp.bp.105.017236CrossRefGoogle ScholarPubMed
Wade, D, Harrigan, S, McGorry, PD, Burgess, PM and Whelan, G (2007a). Impact of severity of substance use disorder on symptomatic and functional outcome in young individuals with first-episode psychosis. Journal of Clinical Psychiatry 68, 767.10.4088/JCP.v68n0517CrossRefGoogle Scholar
World Health Organization (WHO) (2019). International Classification of Diseases, Eleventh Revision (ICD-11), World Health Organization (WHO) 2019. https://icd.who.int/browse11 Google Scholar
Williams, BD, Lee, K, Ewah, SO and Neelam, K (2024). Aripiprazole and other third-generation antipsychotics as a risk factor for impulse control disorders: A systematic review and meta-analysis. Journal of Clinical Psychopharmacology 44, 3948.10.1097/JCP.0000000000001773CrossRefGoogle ScholarPubMed
Wisdom, JP, Manuel, JI and Drake, RE (2011). Substance use disorder among people with first-episode psychosis: A systematic review of course and treatment. Psychiatric Services 62, 10071012.10.1176/ps.62.9.pss6209_1007CrossRefGoogle Scholar
Xu, LX, Wu, LL, Geng, XM, Wang, ZL, Guo, XY, Song, KR, Liu, GQ, Deng, LY, Zhang, JT and Potenza, MN (2021). A review of psychological interventions for internet addiction. Psychiatry Research 302, 114016.10.1016/j.psychres.2021.114016CrossRefGoogle ScholarPubMed
Yakovenko, I, Clark, CM, Hodgins, DC and Goghari, VM (2016). A qualitative analysis of the effects of a comorbid disordered gambling diagnosis with schizophrenia. Schizophrenia Research 171, 5055.10.1016/j.schres.2015.12.008CrossRefGoogle ScholarPubMed
Zajac, K, Ginley, MK and Chang, R (2020). Treatments of internet gaming disorder: A systematic review of the evidence. Expert Review of Neurotherapeutics 20, 8593.10.1080/14737175.2020.1671824CrossRefGoogle ScholarPubMed
Zajac, K, Ginley, MK, Chang, R and Petry, NM (2017). Treatments for internet gaming disorder and internet addiction: A systematic review. Psychology of Addictive Behaviors 31, 979.10.1037/adb0000315CrossRefGoogle ScholarPubMed
Zanelli, J, Mollon, J, Sandin, S, Morgan, C, Dazzan, P, Pilecka, I, Reis Marques, T, David, AS, Morgan, K, Fearon, P, Doody, GA, Jones, PB, Murray, RM and Reichenberg, A (2019). Cognitive change in schizophrenia and other psychoses in the decade following the first episode. Am J Psychiatry 176, 811819.10.1176/appi.ajp.2019.18091088CrossRefGoogle ScholarPubMed
Zhang, L, Luo, T, Hao, W, Cao, Y, Yuan, M and Liao, Y (2022). Gaming disorder symptom questionnaire: The development and validation of a screening tool for ICD-11 gaming disorder in adolescents. Front Psychiatry 13, 848157.10.3389/fpsyt.2022.848157CrossRefGoogle ScholarPubMed
Zhang, TH, Li, HJ, Stone, WS, Woodberry, KA, Seidman, LJ, Tang, YY, Guo, Q, Zhuo, KM, Qian, ZY, Cui, HR, Zhu, YK, Jiang, LJ, Chow, A, Tang, YX, Li, CB, Jiang, KD, Yi, ZH, Xiao, ZP, Wang, JJ and van Amelsvoort, T (2015). Neuropsychological impairment in Prodromal, first-episode, and chronic psychosis: Assessing RBANS performance. PLoS One 10, e0125784.10.1371/journal.pone.0125784CrossRefGoogle ScholarPubMed