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Penicillin allergy delabeling practices and barriers across SHEA research network US institutions: a cross-sectional survey

Published online by Cambridge University Press:  14 October 2025

Kap Sum Foong Open the ORCID record for Kap Sum Foong [Opens in a new window] ,
Rachel Erdil Open the ORCID record for Rachel Erdil [Opens in a new window] ,
Maureen Campion Open the ORCID record for Maureen Campion [Opens in a new window] ,
Shira Doron  and
Majd Alsoubani Open the ORCID record for Majd Alsoubani [Opens in a new window]
Kap Sum Foong*
Affiliation:
Division of Geographic Medicine & Infectious Disease, Tufts Medical Center, Boston, MA, USA
Rachel Erdil
Affiliation:
Division of Geographic Medicine & Infectious Disease, Tufts Medical Center, Boston, MA, USA
Maureen Campion
Affiliation:
Division of Geographic Medicine & Infectious Disease, Tufts Medical Center, Boston, MA, USA
Shira Doron
Affiliation:
Division of Geographic Medicine & Infectious Disease, Tufts Medical Center, Boston, MA, USA
Majd Alsoubani
Affiliation:
Division of Geographic Medicine & Infectious Disease, Tufts Medical Center, Boston, MA, USA
*
Corresponding author: Kap Sum Foong; Email: kapsum.foong@tuftsmedicine.org
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Abstract

We surveyed SHEA Research Network institutions in the U.S. to characterize penicillin allergy delabeling practices. Although most institutions reported active delabeling programs, we found substantial variability in these initiatives. Reported barriers included minimal electronic health record (EHR) integration and time constraints. Expanding non-allergist-led programs and EHR integration are critical to optimizing and advancing delabeling.

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Concise Communication
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Infection Control & Hospital Epidemiology , First View , pp. 1 - 4
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Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Shenoy, ES, Macy, E, Rowe, T, Blumenthal, KG. Evaluation and management of penicillin allergy: a review. Jama 2019;321:188–199 10.1001/jama.2018.19283CrossRefGoogle ScholarPubMed
Krah, NM, Jones, TW, Lake, J, Hersh, AL. The impact of antibiotic allergy labels on antibiotic exposure, clinical outcomes, and healthcare costs: a systematic review. Infect Control Hosp Epidemiol 2021;42:530–548 10.1017/ice.2020.1229CrossRefGoogle ScholarPubMed
Staicu, ML, Vyles, D, Shenoy, ES, et al. Penicillin allergy delabeling: a multidisciplinary opportunity. J Allergy Clin Immunol Pract 2020;8:2858–2868.e16 10.1016/j.jaip.2020.04.059CrossRefGoogle Scholar
Mancini, CM, Fu, X, Zhang, Y, et al. Penicillin allergy evaluation access: a national survey. Clin Infect Dis 2020;71:2972–2975 10.1093/cid/ciaa567CrossRefGoogle ScholarPubMed
Chow, TG, McDanel, DL, Turner, NA, Copaescu, AM. Nonallergist delabeling-should penicillin allergy delabeling only be performed by allergists? J Allergy Clin Immunol Pract 2025;13:1011–1017.e2 10.1016/j.jaip.2024.11.028CrossRefGoogle Scholar
Samarakoon, U, Accarino, J, Wurcel, AG, Jaggers, J, Judd, A, Blumenthal, KG. Penicillin allergy delabeling: opportunities for implementation and dissemination. Ann Allergy Asthma Immunol 2023;130:554–564 10.1016/j.anai.2022.12.023CrossRefGoogle ScholarPubMed
Powell, N, Elkhalifa, S, Guyer, A, Garcez, T, Sandoe, J, Zhou, L. Addressing the challenges of penicillin allergy delabeling with electronic health records and mobile applications. J Allergy Clin Immunol Pract 2023;11:414–421 10.1016/j.jaip.2022.10.037CrossRefGoogle ScholarPubMed
Dong, Y, Zembles, TN, Nimmer, M, Brousseau, DC, Vyles, D. A potential cost savings analysis of a penicillin de-labeling program. Front Allergy 2023;4:1101321 10.3389/falgy.2023.1101321CrossRefGoogle ScholarPubMed
Cooper, L, Harbour, J, Sneddon, J, Seaton, RA. Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge: a systematic review. JAC Antimicrob Resist 2021;3:dlaa123 10.1093/jacamr/dlaa123CrossRefGoogle Scholar
Staub, M, Nelson, GE, Byrge, K, et al. Impacts of risk-stratified inpatient penicillin allergy label delabeling on subsequent antimicrobial spectrum index and costs. Antimicrob Steward Healthc Epidemiol 2024;4:e160 10.1017/ash.2024.421CrossRefGoogle Scholar
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