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Pigs experimentally infected with Serpulina hyodysenteriae can be protected from developing swine dysentery by feeding them a highly digestible diet

Published online by Cambridge University Press:  15 May 2009

P. M. Siba ,
D. W. Pethick  and
D. J. Hampson
P. M. Siba
Affiliation:
School of Veterinary Studies, Murdoch University, Murdoch, Western Australia 6150, Australia
D. W. Pethick
Affiliation:
School of Veterinary Studies, Murdoch University, Murdoch, Western Australia 6150, Australia
D. J. Hampson*
Affiliation:
School of Veterinary Studies, Murdoch University, Murdoch, Western Australia 6150, Australia
*
* Corresponding author.
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Weaner pigs (n = 72) were fed 1 of 4 diets. These were based on either cooked rice and animal protein, cooked rice and lupin, wheat and lupin, or wheat and animal protein. Twenty-six of the pigs were slaughtered after 1 month. Those fed the highly digestible cooked rice and animal protein diet had drier colonic contents and faeces, lighter large intestines, and the contents of their large intestines had increased pH values and decreased total VFA concentrations. The other 46 pigs were orally challenged with broth cultures of Serpulina hyodysenteriae, and were monitored for faecal excretion of the spirochaetes, and for the development of swine dysentery (SD). None of 18 pigs fed the cooked rice and animal protein diet developed colonic changes or disease, whereas most pigs on the other diets developed mucohaemorrhagic colitis and dysentery. The reduced fermentation that occurred in the large intestines of pigs fed cooked rice and animal protein was associated with a subsequent failure of colonization by S. hyodysenteriae, and resultant protection against SD.

Information

Type
Research Article
Information
Epidemiology & Infection , Volume 116 , Issue 2 , April 1996 , pp. 207 - 216
Copyright
Copyright © Cambridge University Press 1996

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